PDB: 82203 件ウェブページステータス検索Chemie searchBIRD

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8J0K	Crystal structure of human TFAP2A in complex with DNA 分子名称: DNA (5'-D(*CP*TP*GP*CP*CP*TP*CP*GP*GP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*CP*GP*AP*GP*GP*CP*AP*G)-3'), GLYCEROL, ... 著者 Liu, K, Xiao, Y.Q, Li, W.F, Min, J.R. 登録日 2023-04-11 公開日 2023-07-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors. Nucleic Acids Res., 51, 2023
8J0R	Structure of human TFAP2A in complex with DNA 分子名称: DI(HYDROXYETHYL)ETHER, DNA (5'-D(*CP*TP*GP*CP*CP*TP*CP*AP*GP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*CP*TP*GP*AP*GP*GP*CP*AP*G)-3'), ... 著者 Liu, K, Xiao, Y.Q, Li, W.F, Min, J.R. 登録日 2023-04-11 公開日 2023-07-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis for specific DNA sequence motif recognition by the TFAP2 transcription factors. Nucleic Acids Res., 51, 2023
4WF7	Crystal structures of trehalose synthase from Deinococcus radiodurans reveal that a closed conformation is involved in the intramolecular isomerization catalysis 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, MAGNESIUM ION, ... 著者 Wang, Y.L, Chow, S.Y, Lin, Y.T, Hsieh, Y.C, Lee, G.C, Liaw, S.H. 登録日 2014-09-13 公開日 2014-12-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structures of trehalose synthase from Deinococcus radiodurans reveal that a closed conformation is involved in catalysis of the intramolecular isomerization. Acta Crystallogr.,Sect.D, 70, 2014
7RWU	Crystal structure of Ni-bound RIDC1 variant in the presence of reductant 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, HEME C, ... 著者 Kakkis, A, Golub, E. 登録日 2021-08-20 公開日 2022-06-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Redox- and metal-directed structural diversification in designed metalloprotein assemblies. Chem.Commun.(Camb.), 58, 2022
4WHE	Crystal structure of E. coli phage shock protein A (PspA 1-144) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Phage shock protein A 著者 Parthier, C, Schoepfel, M, Stubbs, M.T, Osadnik, H, Brueser, T. 登録日 2014-09-22 公開日 2015-09-02 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 PspF-binding domain PspA1-144 and the PspAF complex: New insights into the coiled-coil-dependent regulation of AAA+ proteins. Mol.Microbiol., 98, 2015
5IGA	Crystal structure of a marine metagenome TRAP solute binding protein specific for aromatic acid ligands (Sorcerer II Global Ocean Sampling Expedition, unidentified microbe, locus tag GOS_1523157, Triple Surface Mutant K158A_K223A_K313A) in complex with co-purified parahydroxybenzoate 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, P-HYDROXYBENZOIC ACID, ... 著者 Vetting, M.W, Al Obaidi, N.F, Hogle, S.L, Dupont, C.L, Almo, S.C. 登録日 2016-02-27 公開日 2017-01-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Crystal structure of a marine metagenome TRAP solute binding protein specific for aromatic acid ligands (Sorcerer II Global Ocean Sampling Expedition, unidentified microbe, locus tag GOS_1523157, Triple Surface Mutant K158A_K223A_K313A) in complex with co-purified parahydroxybenzoate To be published
5INJ	Crystal Structure of Prenyltransferase PriB Ternary Complex with L-Tryptophan and Dimethylallyl thiolodiphosphate (DMSPP) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYLALLYL S-THIOLODIPHOSPHATE, Prenyltransferase, ... 著者 Cao, H, Elshahawi, S, Benach, J, Wasserman, S.R, Morisco, L.L, Koss, J.W, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) 登録日 2016-03-07 公開日 2016-05-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure and specificity of a permissive bacterial C-prenyltransferase. Nat. Chem. Biol., 13, 2017
5U3R	Human PPARdelta ligand-binding domain in complexed with specific agonist 2 分子名称: 6-[2-({[4-(furan-2-yl)benzene-1-carbonyl](propan-2-yl)amino}methyl)phenoxy]hexanoic acid, DI(HYDROXYETHYL)ETHER, Peroxisome proliferator-activated receptor delta, ... 著者 Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P. 登録日 2016-12-03 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
1PIF	PIG ALPHA-AMYLASE 分子名称: ALPHA-AMYLASE, CALCIUM ION, CHLORIDE ION 著者 Machius, M, Vertesy, L, Huber, R, Wiegand, G. 登録日 1996-06-15 公開日 1996-12-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Carbohydrate and protein-based inhibitors of porcine pancreatic alpha-amylase: structure analysis and comparison of their binding characteristics. J.Mol.Biol., 260, 1996
6FK3	Structure and function of aldehyde dehydrogenase from Thermus thermophilus: An enzyme with an evolutionarily-distinct C-terminal arm (Recombinant full-length protein in complex with propanal) 分子名称: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Aldehyde dehydrogenase, DI(HYDROXYETHYL)ETHER, ... 著者 Hayes, K.A, Noor, M.R, Djeghader, A, Soulimane, T. 登録日 2018-01-23 公開日 2018-09-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The quaternary structure of Thermus thermophilus aldehyde dehydrogenase is stabilized by an evolutionary distinct C-terminal arm extension. Sci Rep, 8, 2018
3DIB	Crystal structure of bovine pancreatic ribonuclease A variant (I106A) 分子名称: CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION 著者 Kurpiewska, K, Font, J, Ribo, M, Vilanova, M, Lewinski, K. 登録日 2008-06-20 公開日 2008-07-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability Proteins, 77, 2009
5U3S	Human PPARdelta ligand-binding domain in complexed with specific agonist 3 分子名称: 6-[2-({[4-(furan-3-yl)benzene-1-carbonyl](propan-2-yl)amino}methyl)phenoxy]hexanoic acid, DI(HYDROXYETHYL)ETHER, POTASSIUM ION, ... 著者 Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P. 登録日 2016-12-03 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3DIC	Crystal structure of bovine pancreatic ribonuclease A variant (V108A) 分子名称: CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION 著者 Kurpiewska, K, Font, J, Ribo, M, Vilanova, M, Lewinski, K. 登録日 2008-06-20 公開日 2008-07-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability Proteins, 77, 2009
7ZHD	Crystal structure of CtaZ in complex with Closthioamide 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SODIUM ION, Transcription activator effector binding, ... 著者 Gude, F, Molloy, E.M, Horch, T, Dell, M, Dunbar, K.L, Krabbe, J, Groll, M, Hertweck, C. 登録日 2022-04-06 公開日 2022-11-09 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 A Specialized Polythioamide-Binding Protein Confers Antibiotic Self-Resistance in Anaerobic Bacteria. Angew.Chem.Int.Ed.Engl., 61, 2022
4AQL	HUMAN GUANINE DEAMINASE IN COMPLEX WITH VALACYCLOVIR 分子名称: 2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate, GUANINE DEAMINASE, ZINC ION 著者 Welin, M, Egeblad, L, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nyman, T, Persson, C, Schuler, H, Thorsell, A.G, Tresaugues, L, Weigelt, J, Nordlund, P. 登録日 2012-04-18 公開日 2012-05-02 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Pan-Pathway Based Interaction Profiling of Fda-Approved Nucleoside and Nucleobase Analogs with Enzymes of the Human Nucleotide Metabolism. Plos One, 7, 2012
5U3T	Human PPARdelta ligand-binding domain in complexed with specific agonist 4 分子名称: 6-[2-({(propan-2-yl)[4-(thiophen-3-yl)benzene-1-carbonyl]amino}methyl)phenoxy]hexanoic acid, DI(HYDROXYETHYL)ETHER, Peroxisome proliferator-activated receptor delta, ... 著者 Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P. 登録日 2016-12-03 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3DI8	Crystal structure of bovine pancreatic ribonuclease A variant (V57A) 分子名称: CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION 著者 Kurpiewska, K, Font, J, Ribo, M, Vilanova, M, Lewinski, K. 登録日 2008-06-20 公開日 2008-07-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability Proteins, 77, 2009
3DH5	Crystal structure of bovine pancreatic ribonuclease A (wild-type) 分子名称: CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION 著者 Kurpiewska, K, Font, J, Ribo, M, Vilanova, M, Lewinski, K. 登録日 2008-06-17 公開日 2008-07-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability Proteins, 77, 2009
3DI7	Crystal structure of bovine pancreatic ribonuclease A variant (V54A) 分子名称: CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION 著者 Kurpiewska, K, Font, J, Ribo, M, Vilanova, M, Lewinski, K. 登録日 2008-06-20 公開日 2008-07-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability Proteins, 77, 2009
5U3Q	Human PPARdelta ligand-binding domain in complexed with specific agonist 1 分子名称: 6-(2-{[([1,1'-biphenyl]-4-carbonyl)(propan-2-yl)amino]methyl}phenoxy)hexanoic acid, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... 著者 Wu, C.-C, Baiga, T.J, Downes, M, La Clair, J.J, Atkins, A.R, Richard, S.B, Stockley-Noel, T.A, Bowman, M.E, Evans, R.M, Noel, J.P. 登録日 2016-12-03 公開日 2017-03-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
2B4B	SSAT+COA+BE-3-3-3, K26R mutant 分子名称: COENZYME A, Diamine acetyltransferase 1, N-ETHYL-N-[3-(PROPYLAMINO)PROPYL]PROPANE-1,3-DIAMINE 著者 Bewley, M.C, Graziano, V, Jiang, J.S, Matz, E, Studier, F.W, Pegg, A.P, Coleman, C.S, Flanagan, J.M, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2005-09-23 公開日 2006-01-17 最終更新日 2023-05-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target Proc.Natl.Acad.Sci.Usa, 103, 2006
5O3I	Human Brd2(BD2) mutant in complex with AL-tBu 分子名称: (2~{S})-1-[(2~{S})-2-oxidanylpropoxy]propan-2-ol, Bromodomain-containing protein 2, CHLORIDE ION, ... 著者 Chan, K.-H, Runcie, A.C, Ciulli, A. 登録日 2017-05-23 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Optimization of a "bump-and-hole" approach to allele-selective BET bromodomain inhibition. Chem Sci, 9, 2018
5VKD	Crystal structure of C-terminal domain of Ebola (Bundibugyo) nucleoprotein in complex with Fab fragment 分子名称: Fab Heavy Chain, Fab light chain, Nucleoprotein 著者 Radwanska, M.J, Derewenda, U, Kossiakoff, A, Derewenda, Z.S. 登録日 2017-04-21 公開日 2018-04-25 最終更新日 2022-11-16 実験手法 X-RAY DIFFRACTION (1.749 Å) 主引用文献 The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab. Acta Crystallogr D Struct Biol, 74, 2018
3GW5	Crystal structure of human renin complexed with a novel inhibitor 分子名称: (3R)-3-[(1S)-1-(3-chlorophenyl)-1-hydroxy-5-methoxypentyl]-N-{(1S)-2-cyclohexyl-1-[(methylamino)methyl]ethyl}piperidine-1-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Wu, Z, McKeever, B.M. 登録日 2009-03-31 公開日 2009-06-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Design and optimization of renin inhibitors: Orally bioavailable alkyl amines. Bioorg.Med.Chem.Lett., 19, 2009
3DI9	Crystal structure of bovine pancreatic ribonuclease A variant (I81A) 分子名称: CHLORIDE ION, Ribonuclease pancreatic, SULFATE ION 著者 Kurpiewska, K, Font, J, Ribo, M, Vilanova, M, Lewinski, K. 登録日 2008-06-20 公開日 2008-07-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 X-ray crystallographic studies of RNase A variants engineered at the most destabilizing positions of the main hydrophobic core: further insight into protein stability Proteins, 77, 2009

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