PDB: 97814 件ウェブページステータス検索Chemie searchBIRD

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8Q5I	Structure of Candida albicans 80S ribosome in complex with cephaeline 分子名称: 18S ribosomal RNA, 25S rRNA, 40S ribosomal protein S0, ... 著者 Kolosova, O, Zgadzay, Y, Stetsenko, A, Atamas, A, Guskov, A, Yusupov, M. 登録日 2023-08-09 公開日 2023-09-13 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (2.45 Å) 主引用文献 Structural characterization of cephaeline binding to the eukaryotic ribosome using Cryo-Electron Microscopy Biopolym Cell, 2023
8D74	Cryo-EM structure of human CNTF signaling complex: model containing the interaction core region 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ciliary neurotrophic factor, ... 著者 Zhou, Y, Franklin, M.C. 登録日 2022-06-07 公開日 2023-03-29 実験手法 ELECTRON MICROSCOPY (3.03 Å) 主引用文献 Structural insights into the assembly of gp130 family cytokine signaling complexes. Sci Adv, 9, 2023
6CE9	Insulin Receptor ectodomain in complex with two insulin molecules 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. 登録日 2018-02-11 公開日 2018-03-14 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
1B16	ALCOHOL DEHYDROGENASE FROM DROSOPHILA LEBANONENSIS TERNARY COMPLEX WITH NAD-3-PENTANONE 分子名称: NICOTINAMIDE ADENINE DINUCLEOTIDE 3-PENTANONE ADDUCT, PROTEIN (ALCOHOL DEHYDROGENASE) 著者 Benach, J, Atrian, S, Gonzalez-Duarte, R, Ladenstein, R. 登録日 1998-11-25 公開日 1999-11-29 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 The catalytic reaction and inhibition mechanism of Drosophila alcohol dehydrogenase: observation of an enzyme-bound NAD-ketone adduct at 1.4 A resolution by X-ray crystallography. J.Mol.Biol., 289, 1999
6CEB	Insulin Receptor ectodomain in complex with two insulin molecules - C1 symmetry 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. 登録日 2018-02-11 公開日 2018-03-14 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
3DRC	INVESTIGATION OF THE FUNCTIONAL ROLE OF TRYPTOPHAN-22 IN ESCHERICHIA COLI DIHYDROFOLATE REDUCTASE BY SITE-DIRECTED MUTAGENESIS 分子名称: CALCIUM ION, CHLORIDE ION, DIHYDROFOLATE REDUCTASE, ... 著者 Oatley, S.J, Kraut, J. 登録日 1992-09-22 公開日 1994-01-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Investigation of the functional role of tryptophan-22 in Escherichia coli dihydrofolate reductase by site-directed mutagenesis. Biochemistry, 30, 1991
6CE7	Insulin Receptor ectodomain in complex with one insulin molecule 分子名称: Insulin A chain, Insulin B chain, Insulin receptor, ... 著者 Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B. 登録日 2018-02-11 公開日 2018-03-14 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Nature, 556, 2018
6T9U	Bovine Trypsine in complex with the synthetic inhibitor (S)-3'-(N-(1-(4-(3-(tert-butyl)ureido)piperidin-1-yl)-3-(3-carbamimidoylphenyl)-1-oxopropan-2-yl)sulfamoyl)-[1,1'-biphenyl]-3-carboximidamide (MI-490) 分子名称: 1-~{tert}-butyl-3-[1-[(2~{S})-3-(3-carbamimidoylphenyl)-2-[[3-(3-carbamimidoylphenyl)phenyl]sulfonylamino]propanoyl]piperidin-4-yl]urea, CALCIUM ION, Cationic Trypsin, ... 著者 Mueller, J.M, Merkl, S, Keils, A, Pilgram, O, Steinmetzer, T. 登録日 2019-10-28 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.067509 Å) 主引用文献 Improving the selectivity of 3-amidinophenylalanine-derived matriptase inhibitors Eur.J.Med.Chem., 2022
8XT1	Cryo-EM structure of the human 39S mitoribosome with 5uM Tigecycline 分子名称: 16s rRNA, 39S ribosomal protein L22, mitochondrial, ... 著者 Li, X, Wang, M, Cheng, J. 登録日 2024-01-10 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
8XT3	Cryo-EM structure of the human 39S mitoribosome with 10uM Tigecycline 分子名称: 16s rRNA, 39S ribosomal protein L22, mitochondrial, ... 著者 Li, X, Wang, M, Cheng, J. 登録日 2024-01-10 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
5LH9	Amine transaminase crystal structure from an uncultivated Pseudomonas species in the PLP-bound (internal aldimine) form 分子名称: OMEGA TRANSAMINASE, PYRIDOXAL-5'-PHOSPHATE 著者 Reddem, E, Thunnissen, A.M.W.H. 登録日 2016-07-10 公開日 2017-03-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Explaining Operational Instability of Amine Transaminases: Substrate-Induced Inactivation Mechanism and Influence of Quaternary Structure on Enzyme-Cofactor Intermediate Stability. Acs Catalysis, 7, 2017
8XT0	Cryo-EM structure of the human 55S mitoribosome with 5um Tigecycline 分子名称: 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ... 著者 Li, X, Wang, M, Cheng, J. 登録日 2024-01-10 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
8XT2	Cryo-EM structure of the human 55S mitoribosome with 10uM Tigecycline 分子名称: 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ... 著者 Li, X, Wang, M, Cheng, J. 登録日 2024-01-10 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
8XE4	norbelladine 4'-O-methyltransferase complexed with Mg, SAH, and norbelladine 分子名称: GLYCEROL, MAGNESIUM ION, Norbelladine, ... 著者 Saw, Y.Y.H, Nakashima, Y, Morita, H. 登録日 2023-12-11 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases Acs Catalysis, 2024
6T9V	Bovine Trypsin in complex with the synthetic inhibitor (S)-3-(3-(4-(3-(tert-butyl)ureido)piperidin-1-yl)-2-((3'-fluoro-4'-(hydroxymethyl)-[1,1'-biphenyl])-3-sulfonamido)-3-oxopropyl)benzimidamide (MI-1904) 分子名称: 1-~{tert}-butyl-3-[1-[(2~{S})-3-(3-carbamimidoylphenyl)-2-[[3-[3-fluoranyl-4-(hydroxymethyl)phenyl]phenyl]sulfonylamino ]propanoyl]piperidin-4-yl]urea, CALCIUM ION, Cationic Trypsin, ... 著者 Merkl, S, Keils, A, Mueller, J.M, Pilgram, O, Steinmetzer, T. 登録日 2019-10-28 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.12642729 Å) 主引用文献 Improving the selectivity of 3-amidinophenylalanine-derived matriptase inhibitors Eur.J.Med.Chem., 2022
8XDT	O-methyltransferase from Lycoris longituba M52T variant complexed with Mg and SAH 分子名称: MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, norbelladine O-methyltransferase 著者 Saw, Y.Y.H, Nakashima, Y, Morita, H. 登録日 2023-12-11 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases Acs Catalysis, 2024
3ETW	Crystal Structure of bacterial adhesin FadA 分子名称: Adhesin A, THIOCYANATE ION 著者 Nithianantham, S, Xu, M, Wu, N, Shoham, M, Han, Y.W. 登録日 2008-10-08 公開日 2008-12-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of FadA Adhesin from Fusobacterium nucleatum Reveals a Novel Oligomerization Motif, the Leucine Chain. J.Biol.Chem., 284, 2009
8XE5	norbelladine 4'-O-methyltransferase complexed with Mg, SAH, and 3,4-dihydroxybenzaldehyde 分子名称: GLYCEROL, MAGNESIUM ION, Norbelladine 4'-O-methyltransferase, ... 著者 Saw, Y.Y.H, Nakashima, Y, Morita, H. 登録日 2023-12-11 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases Acs Catalysis, 2024
8XDR	O-methyltransferase from Lycoris aurea complexed with Mg, SAH, and 3,4-dihydroxybenzaldehyde 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MAGNESIUM ION, ... 著者 Saw, Y.Y.H, Nakashima, Y, Morita, H. 登録日 2023-12-11 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases Acs Catalysis, 2024
8XDO	O-methyltransferase from Lycoris longituba complexed with Mg and SAH 分子名称: GLYCEROL, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Saw, Y.Y.H, Nakashima, Y, Morita, H. 登録日 2023-12-11 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases Acs Catalysis, 2024
8XDQ	O-methyltransferase from Lycoris aurea complexed with Mg and SAH 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MAGNESIUM ION, ... 著者 Saw, Y.Y.H, Nakashima, Y, Morita, H. 登録日 2023-12-11 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases Acs Catalysis, 2024
8XDP	O-methyltransferase from Lycoris longituba complexed with Mg, SAH, and 3,4-dihydroxybenzaldehyde 分子名称: GLYCEROL, MAGNESIUM ION, Protocatechuic aldehyde, ... 著者 Saw, Y.Y.H, Nakashima, Y, Morita, H. 登録日 2023-12-11 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases Acs Catalysis, 2024
8XE3	norbelladine 4'-O-methyltransferase complexed with Mg and SAH 分子名称: GLYCEROL, MAGNESIUM ION, Norbelladine 4'-O-methyltransferase, ... 著者 Saw, Y.Y.H, Nakashima, Y, Morita, H. 登録日 2023-12-11 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases Acs Catalysis, 2024
8XE0	O-methyltransferase from Lycoris longituba M52W variant complexed with Mg, SAH, and 3,4-dihydroxybenzaldehyde 分子名称: MAGNESIUM ION, Protocatechuic aldehyde, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Saw, Y.Y.H, Nakashima, Y, Morita, H. 登録日 2023-12-11 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases Acs Catalysis, 2024
8XDU	O-methyltransferase from Lycoris longituba M52S variant complexed with Mg and SAH 分子名称: GLYCEROL, MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Saw, Y.Y.H, Nakashima, Y, Morita, H. 登録日 2023-12-11 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (1.92 Å) 主引用文献 Structure-Based Catalytic Mechanism of Amaryllidaceae O-Methyltransferases Acs Catalysis, 2024

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