1S63
 
 | | Human protein farnesyltransferase complexed with L-778,123 and FPP | | 分子名称: | 4-[(5-{[4-(3-CHLOROPHENYL)-3-OXOPIPERAZIN-1-YL]METHYL}-1H-IMIDAZOL-1-YL)METHYL]BENZONITRILE, FARNESYL DIPHOSPHATE, Protein farnesyltransferase beta subunit, ... | | 著者 | Long, S.B, Casey, P.J, Beese, L.S. | | 登録日 | 2004-01-22 | | 公開日 | 2004-07-27 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystallographic Analysis Reveals that Anticancer Clinical Candidate L-778,123 Inhibits Protein Farnesyltransferase and Geranylgeranyltransferase-I by Different Binding Modes.
Biochemistry, 43, 2004
|
|
1SA4
 | | human protein farnesyltransferase complexed with FPP and R115777 | | 分子名称: | 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE, FARNESYL DIPHOSPHATE, Protein farnesyltransferase beta subunit, ... | | 著者 | Reid, T.S, Beese, L.S. | | 登録日 | 2004-02-06 | | 公開日 | 2004-06-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structures of the Anticancer Clinical Candidates R115777 (Tipifarnib) and BMS-214662 Complexed with Protein Farnesyltransferase Suggest a Mechanism of FTI Selectivity.
Biochemistry, 43, 2004
|
|
1TJ4
 | | X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in complex with sucrose | | 分子名称: | MAGNESIUM ION, Sucrose-Phosphatase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | 著者 | Fieulaine, S, Lunn, J.E, Borel, F, Ferrer, J.-L. | | 登録日 | 2004-06-03 | | 公開日 | 2005-06-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell.
Plant Cell, 17, 2005
|
|
1TJ5
 | | X-Ray structure of the Sucrose-Phosphatase (SPP) from Synechocystis sp. PCC6803 in complex with sucrose and phosphate | | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, Sucrose-Phosphatase, ... | | 著者 | Fieulaine, S, Lunn, J.E, Borel, F, Ferrer, J.-L. | | 登録日 | 2004-06-03 | | 公開日 | 2005-06-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The structure of a cyanobacterial sucrose-phosphatase reveals the sugar tongs that release free sucrose in the cell.
Plant Cell, 17, 2005
|
|
1TN6
 | | Protein Farnesyltransferase Complexed with a Rap2a Peptide Substrate and a FPP Analog at 1.8A Resolution | | 分子名称: | ACETIC ACID, Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ... | | 著者 | Reid, T.S, Terry, K.L, Casey, P.J, Beese, L.S. | | 登録日 | 2004-06-11 | | 公開日 | 2004-11-02 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity
J.Mol.Biol., 343, 2004
|
|
1U45
 | | 8oxoguanine at the pre-insertion site of the polymerase active site | | 分子名称: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | | 著者 | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | | 登録日 | 2004-07-23 | | 公開日 | 2004-09-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
Nature, 431, 2004
|
|
1U47
 | | cytosine-8-Oxoguanine base pair at the polymerase active site | | 分子名称: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | | 著者 | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | | 登録日 | 2004-07-23 | | 公開日 | 2004-09-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
Nature, 431, 2004
|
|
1U48
 | | Extension of a cytosine-8-oxoguanine base pair | | 分子名称: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | | 著者 | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | | 登録日 | 2004-07-23 | | 公開日 | 2004-09-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
Nature, 431, 2004
|
|
1U49
 | | Adenine-8oxoguanine mismatch at the polymerase active site | | 分子名称: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | | 著者 | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | | 登録日 | 2004-07-23 | | 公開日 | 2004-09-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
Nature, 431, 2004
|
|
1U4B
 | | Extension of an adenine-8oxoguanine mismatch | | 分子名称: | DNA polymerase I, DNA primer strand, DNA template strand with 8-oxoguanine, ... | | 著者 | Hsu, G.W, Ober, M, Carell, T, Beese, L.S. | | 登録日 | 2004-07-23 | | 公開日 | 2004-09-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase.
Nature, 431, 2004
|
|
1UA0
 | | Aminofluorene DNA adduct at the pre-insertion site of a DNA polymerase | | 分子名称: | 2-AMINOFLUORENE, DNA polymerase I, DNA primer strand, ... | | 著者 | Hsu, G.W, Kiefer, J.R, Becherel, O.J, Fuchs, R.P.P, Beese, L.S. | | 登録日 | 2004-08-11 | | 公開日 | 2004-09-28 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Observing translesion synthesis of an aromatic amine DNA adduct by a high-fidelity DNA polymerase
J.Biol.Chem., 279, 2004
|
|
1UC2
 | | Hypothetical Extein Protein of PH1602 from Pyrococcus horikoshii | | 分子名称: | SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, hypothetical protein PH1602 | | 著者 | Okada, C, Maegawa, Y, Yao, M, Tanaka, I. | | 登録日 | 2003-04-08 | | 公開日 | 2004-05-04 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Crystal structure of an RtcB homolog protein (PH1602-extein protein) from Pyrococcus horikoshii reveals a novel fold
Proteins, 63, 2006
|
|
1V8X
 | | Crystal Structure of the Dioxygen-bound Heme Oxygenase from Corynebacterium diphtheriae | | 分子名称: | Heme oxygenase, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Unno, M, Matsui, T, Chu, G.C, Couture, M, Yoshida, T, Rousseau, D.L, Olson, J.S, Ikeda-Saito, M. | | 登録日 | 2004-01-15 | | 公開日 | 2004-05-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal Structure of the Dioxygen-bound Heme Oxygenase from Corynebacterium diphtheriae: IMPLICATIONS FOR HEME OXYGENASE FUNCTION.
J.Biol.Chem., 279, 2004
|
|
1X3W
 | | Structure of a peptide:N-glycanase-Rad23 complex | | 分子名称: | UV excision repair protein RAD23, ZINC ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... | | 著者 | Lee, J.-H, Choi, J.M, Lee, C, Yi, K.J, Cho, Y. | | 登録日 | 2005-05-11 | | 公開日 | 2005-06-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structure of a peptide:N-glycanase-Rad23 complex: insight into the deglycosylation for denatured glycoproteins.
Proc.Natl.Acad.Sci.Usa, 102, 2005
|
|
1X3Z
 | | Structure of a peptide:N-glycanase-Rad23 complex | | 分子名称: | UV excision repair protein RAD23, ZINC ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... | | 著者 | Lee, J.-H, Choi, J.M, Lee, C, Yi, K.J, Cho, Y. | | 登録日 | 2005-05-11 | | 公開日 | 2005-06-14 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structure of a peptide:N-glycanase-Rad23 complex: insight into the deglycosylation for denatured glycoproteins.
Proc.Natl.Acad.Sci.Usa, 102, 2005
|
|
1XC9
 | | Structure of a high-fidelity polymerase bound to a benzo[a]pyrene adduct that blocks replication | | 分子名称: | 1,2,3-TRIHYDROXY-1,2,3,4-TETRAHYDROBENZO[A]PYRENE, DNA polymerase I, DNA primer strand, ... | | 著者 | Hsu, G.W, Huang, X, Luneva, N.P, Geacintov, N.E, Beese, L.S. | | 登録日 | 2004-09-01 | | 公開日 | 2004-12-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of a High Fidelity DNA Polymerase Bound to a Benzo[a]pyrene Adduct That Blocks Replication
J.Biol.Chem., 280, 2005
|
|
1XLT
 | | Crystal structure of Transhydrogenase [(domain I)2:domain III] heterotrimer complex | | 分子名称: | NAD(P) transhydrogenase subunit alpha part 1, NAD(P) transhydrogenase subunit beta, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | | 著者 | Sundaresan, V, Chartron, J, Yamaguchi, M, Stout, C.D. | | 登録日 | 2004-09-30 | | 公開日 | 2005-04-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Conformational Diversity in NAD(H) and Transhydrogenase Nicotinamide Nucleotide Binding Domains
J.Mol.Biol., 346, 2005
|
|
1YLJ
 | | Atomic resolution structure of CTX-M-9 beta-lactamase | | 分子名称: | SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase CTX-M-9a | | 著者 | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-19 | | 公開日 | 2005-04-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (0.98 Å) | | 主引用文献 | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability.
J.Mol.Biol., 348, 2005
|
|
1YLP
 | | Atomic resolution structure of CTX-M-27 beta-lactamase | | 分子名称: | SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase CTX-M-27 | | 著者 | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-19 | | 公開日 | 2005-04-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability.
J.Mol.Biol., 348, 2005
|
|
1YLT
 | | Atomic resolution structure of CTX-M-14 beta-lactamase | | 分子名称: | SULFATE ION, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, beta-lactamase CTX-M-14 | | 著者 | Chen, Y, Delmas, J, Sirot, J, Shoichet, B, Bonnet, R. | | 登録日 | 2005-01-19 | | 公開日 | 2005-04-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Atomic Resolution Structures of CTX-M beta-Lactamases: Extended Spectrum Activities from Increased Mobility and Decreased Stability.
J.Mol.Biol., 348, 2005
|
|
1YNP
 | | aldo-keto reductase AKR11C1 from Bacillus halodurans (apo form) | | 分子名称: | GLYCEROL, SODIUM ION, SULFATE ION, ... | | 著者 | Marquardt, T, Kostrewa, D, Winkler, F.K, Li, X.D. | | 登録日 | 2005-01-25 | | 公開日 | 2005-12-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | High-resolution Crystal Structure of AKR11C1 from Bacillus halodurans: An NADPH-dependent 4-Hydroxy-2,3-trans-nonenal Reductase
J.Mol.Biol., 354, 2005
|
|
1YNQ
 | | aldo-keto reductase AKR11C1 from Bacillus halodurans (holo form) | | 分子名称: | GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SODIUM ION, ... | | 著者 | Marquardt, T, Kostrewa, D, Winkler, F.K, Li, X.D. | | 登録日 | 2005-01-25 | | 公開日 | 2005-12-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | High-resolution Crystal Structure of AKR11C1 from Bacillus halodurans: An NADPH-dependent 4-Hydroxy-2,3-trans-nonenal Reductase
J.Mol.Biol., 354, 2005
|
|
1ZS2
 | | Amylosucrase Mutant E328Q in a ternary complex with sucrose and maltoheptaose | | 分子名称: | alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, amylosucrase, ... | | 著者 | Skov, L.K, Mirza, O, Sprogoe, D, van der Veen, B.A, Remaud-Simeon, M, Albenne, C, Monsan, P, Gajhede, M. | | 登録日 | 2005-05-23 | | 公開日 | 2006-05-02 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Crystal structure of the Glu328Gln mutant of Neisseria polysaccharea amylosucrase in complex with sucrose and maltoheptaose
BIOCATAL.BIOTRANSFOR., 24, 2006
|
|
2ADD
 | | Crystal structure of fructan 1-exohydrolase IIa from Cichorium intybus in complex with sucrose | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, ... | | 著者 | Verhaest, M, Le Roy, K, De Ranter, C.J, Van Laere, A, Van den Ende, W, Rabijns, A. | | 登録日 | 2005-07-20 | | 公開日 | 2006-08-29 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Insights into the fine architecture of the active site of chicory fructan 1-exohydrolase: 1-kestose as substrate vs sucrose as inhibitor.
New Phytol, 174, 2007
|
|
2BE2
 | | Crystal structure of HIV-1 reverse transcriptase (RT) in complex with R221239 | | 分子名称: | 4-(3,5-DIMETHYLPHENOXY)-5-(FURAN-2-YLMETHYLSULFANYLMETHYL)-3-IODO-6-METHYLPYRIDIN-2(1H)-ONE, GLYCEROL, MANGANESE (II) ION, ... | | 著者 | Himmel, D.M, Das, K, Clark Jr, A.D, Hughes, S.H, Benjahad, A, Oumouch, S, Guillemont, J, Coupa, S, Poncelet, A, Csoka, I, Meyer, C, Andries, K, Nguyen, C.H, Grierson, D.S, Arnold, E. | | 登録日 | 2005-10-21 | | 公開日 | 2005-12-06 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Crystal Structures for HIV-1 Reverse Transcriptase in Complexes with Three Pyridinone Derivatives: A New Class of Non-Nucleoside Inhibitors Effective against a Broad Range of Drug-Resistant Strains.
J.Med.Chem., 48, 2005
|
|
