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1I31
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MU2 ADAPTIN SUBUNIT (AP50) OF AP2 CLATHRIN ADAPTOR, COMPLEXED WITH EGFR INTERNALIZATION PEPTIDE FYRALM AT 2.5 A RESOLUTION
分子名称: CLATHRIN COAT ASSEMBLY PROTEIN AP50, EPIDERMAL GROWTH FACTOR RECEPTOR
著者Modis, Y, Boll, W, Rapoport, I, Kirchhausen, T.
登録日2001-02-12
公開日2001-02-21
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献MU2 ADAPTIN SUBUNIT (AP50) OF AP2 CLATHRIN ADAPTOR, COMPLEXED WITH EGFR INTERNALIZATION PEPTIDE FYRALM AT 2.5 A RESOLUTION
To be Published
2V8S
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BU of 2v8s by Molmil
VTI1B HABC DOMAIN - EPSINR ENTH DOMAIN COMPLEX
分子名称: CLATHRIN INTERACTOR 1, GLYCEROL, VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B
著者Owen, D.J, McCoy, A.J, Collins, B.M, Miller, S.E.
登録日2007-08-14
公開日2007-11-27
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献A Snare-Adaptor Interaction is a New Mode of Cargo Recognition in Clathrin Coated Vesicles
Nature, 450, 2007
1W63
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AP1 clathrin adaptor core
分子名称: ADAPTER-RELATED PROTEIN COMPLEX 1 BETA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 GAMMA 1 SUBUNIT, ADAPTER-RELATED PROTEIN COMPLEX 1 SIGMA 1A SUBUNIT, ...
著者Heldwein, E, Macia, E, Wang, J, Yin, H.L, Kirchhausen, T, Harrison, S.C.
登録日2004-08-12
公開日2004-09-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal Structure of the Clathrin Adaptor Protein 1 Core
Proc.Natl.Acad.Sci.USA, 101, 2004
1N4C
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BU of 1n4c by Molmil
NMR Structure of the J-Domain and Clathrin Substrate Binding Domain of Bovine Auxilin
分子名称: Auxilin
著者Gruschus, J.M, Han, C.J, Greener, T, Greene, L.E, Ferretti, J.A, Eisenberg, E.
登録日2002-10-30
公開日2003-11-11
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the functional fragment of auxilin required for catalytic uncoating of clathrin-coated vesicles.
Biochemistry, 43, 2004
4P6Z
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BU of 4p6z by Molmil
Crystal structure of the human BST2 cytoplasmic domain and the HIV-1 Vpu cytoplasmic domain bound to the clathrin adaptor protein complex 1 (AP1) core
分子名称: AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, AP-1 complex subunit mu-1, ...
著者Jia, X, Xiong, Y.
登録日2014-03-25
公開日2014-05-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis of HIV-1 Vpu-mediated BST2 antagonism via hijacking of the clathrin adaptor protein complex 1.
Elife, 3, 2014
4HMY
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BU of 4hmy by Molmil
Structural basis for recruitment and activation of the AP-1 clathrin adaptor complex by Arf1
分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Ren, X, Farias, G.G, Canagarajah, B.J, Bonifacino, J.S, Hurley, J.H.
登録日2012-10-18
公開日2013-03-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (7 Å)
主引用文献Structural Basis for Recruitment and Activation of the AP-1 Clathrin Adaptor Complex by Arf1.
Cell(Cambridge,Mass.), 152, 2013
3ZYL
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BU of 3zyl by Molmil
Structure of a truncated CALM (PICALM) ANTH domain
分子名称: PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN
著者Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J.
登録日2011-08-23
公開日2011-12-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
Cell, 147, 2011
3ZYM
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Structure of CALM (PICALM) in complex with VAMP8
分子名称: GLYCEROL, PHOSPHATE ION, PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN, ...
著者Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J.
登録日2011-08-23
公開日2011-12-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
Cell, 147, 2011
3ZYK
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BU of 3zyk by Molmil
Structure of CALM (PICALM) ANTH domain
分子名称: PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN
著者Miller, S.E, Sahlender, D.A, Graham, S.C, Honing, S, Robinson, M.S, Peden, A.A, Owen, D.J.
登録日2011-08-23
公開日2011-12-07
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The molecular basis for the endocytosis of small R-SNAREs by the clathrin adaptor CALM.
Cell, 147, 2011
3H85
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Molecular basis for the association of PIPKI gamma-p90 with the clathrin adaptor AP-2
分子名称: AP-2 complex subunit mu-1, NICKEL (II) ION, Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
著者Vahedi-Faridi, A, Kahlfeldt, N, Schaefer, J.G, Haucke, V.
登録日2009-04-28
公開日2009-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis for association of PIPKI gamma-p90 with clathrin adaptor AP-2.
J.Biol.Chem., 285, 2010
7R4H
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BU of 7r4h by Molmil
phospho-STING binding to adaptor protein complex-1
分子名称: ADP-ribosylation factor 1, AP-1 complex subunit beta-1, AP-1 complex subunit gamma-1, ...
著者Xu, P, Ablasser, A.
登録日2022-02-08
公開日2022-09-14
最終更新日2022-11-09
実験手法ELECTRON MICROSCOPY (2.34 Å)
主引用文献Clathrin-associated AP-1 controls termination of STING signalling.
Nature, 610, 2022
2XA7
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AP2 clathrin adaptor core in active complex with cargo peptides
分子名称: ADAPTOR-RELATED PROTEIN COMPLEX 2, ALPHA 2 SUBUNIT, AP-2 COMPLEX SUBUNIT BETA, ...
著者Jackson, L.P, Kelly, B.T, McCoy, A.J, Evans, P.R, Owen, D.J.
登録日2010-03-29
公開日2010-07-21
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A Large Scale Conformational Change Couples Membrane Recruitment to Cargo Binding in the Ap2 Clathrin Adaptor Complex
Cell(Cambridge,Mass.), 141, 2010
3H1Z
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BU of 3h1z by Molmil
Molecular basis for the association of PIPKIgamma -p90 with the clathrin adaptor AP-2
分子名称: AP-2 complex subunit beta-1, Phosphatidylinositol-4-phosphate 5-kinase type-1 gamma
著者Vahedi-Faridi, A, Kahlfeldt, N, Schaefer, J.G, Krainer, G, Keller, S, Saenger, W, Krauss, M, Haucke, V.
登録日2009-04-14
公開日2009-11-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Molecular basis for association of PIPKI gamma-p90 with clathrin adaptor AP-2.
J.Biol.Chem., 285, 2010
2KIG
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A PH domain within OCRL bridges clathrin mediated membrane trafficking to phosphoinositide metabolism
分子名称: Inositol polyphosphate 5-phosphatase II isoform
著者Mao, Y, Hodsdon, M.E, De Camilli, P.
登録日2009-05-03
公開日2009-06-30
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism.
Embo J., 28, 2009
2KIE
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BU of 2kie by Molmil
A PH domain within OCRL bridges clathrin mediated membrane trafficking to phosphoinositide metabolis
分子名称: Inositol polyphosphate 5-phosphatase OCRL-1
著者Mao, Y, Balkin, D.M, Zoncu, R, Erdmann, K, Tomasini, L, Hu, F, Jin, M.M, Hodsdon, M.E, De Camilli, P.
登録日2009-05-03
公開日2009-07-21
最終更新日2022-03-16
実験手法SOLUTION NMR
主引用文献A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism
Embo J., 28, 2009
1W80
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BU of 1w80 by Molmil
Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, bound to 2 peptides from Synaptojanin170
分子名称: ADAPTER-RELATED PROTEIN COMPLEX 2 ALPHA 2 SUBUNIT, BENZAMIDINE, CARBONATE ION, ...
著者Ford, M.G.J, Praefcke, G.J.K, McMahon, H.T.
登録日2004-09-14
公開日2004-10-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Evolving Nature of the Ap2 Alpha-Appendage Hub During Clathrin-Coated Vesicle Endocytosis.
Embo J., 23, 2004
6YAF
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BU of 6yaf by Molmil
AP2 on a membrane containing tyrosine-based cargo peptide
分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
著者Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G.
登録日2020-03-12
公開日2020-07-29
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (9.1 Å)
主引用文献Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles.
Sci Adv, 6, 2020
7RWA
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AP2 bound to heparin and Tgn38 tyrosine cargo peptide
分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
著者Baker, R.W, Hollopeter, G, Partlow, E.A.
登録日2021-08-19
公開日2022-03-30
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization.
Nat.Struct.Mol.Biol., 29, 2022
7RWC
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BU of 7rwc by Molmil
AP2 bound to the APA domain of SGIP and heparin; partial signal subtraction and symmetry expansion
分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
著者Baker, R.W, Hollopeter, G, Partlow, E.A.
登録日2021-08-19
公開日2022-03-30
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization.
Nat.Struct.Mol.Biol., 29, 2022
7RW8
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AP2 bound to heparin in the closed conformation
分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
著者Baker, R.W, Hollopeter, G, Partlow, E.A.
登録日2021-08-19
公開日2022-03-30
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization.
Nat.Struct.Mol.Biol., 29, 2022
7RWB
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BU of 7rwb by Molmil
AP2 bound to the APA domain of SGIP in the presence of heparin
分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
著者Baker, R.W, Hollopeter, G, Partlow, E.A.
登録日2021-08-19
公開日2022-03-30
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization.
Nat.Struct.Mol.Biol., 29, 2022
7RW9
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AP2 bound to heparin in the bowl conformation
分子名称: AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
著者Baker, R.W, Hollopeter, G, Partlow, E.A.
登録日2021-08-19
公開日2022-03-30
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization.
Nat.Struct.Mol.Biol., 29, 2022
6YAE
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AP2 core in physiological buffer
分子名称: AP-2 complex subunit alpha, AP-2 complex subunit beta, AP-2 complex subunit mu, ...
著者Kane Dickson, V, Kovtun, O, Kelly, B.T, Owen, D.J, Briggs, J.A.G.
登録日2020-03-12
公開日2020-07-29
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles.
Sci Adv, 6, 2020
6RH6
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Solution structure and 1H, 13C and 15N chemical shift assignments for the complex of NECAP1 PHear domain with phosphorylated AP2 mu2 148-163
分子名称: AP-2 complex subunit mu, Adaptin ear-binding coat-associated protein 1
著者Owen, D.J, Neuhaus, D, Yang, J.-C, Herrmann, T.
登録日2019-04-18
公開日2019-09-04
実験手法SOLUTION NMR
主引用文献Temporal Ordering in Endocytic Clathrin-Coated Vesicle Formation via AP2 Phosphorylation.
Dev.Cell, 50, 2019
7ZX4
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Clathrin N-terminal domain in complex with a HURP phospho-peptide
分子名称: CHLORIDE ION, Clathrin heavy chain 1, Disks large-associated protein 5, ...
著者Kliche, J, Badgujar, D, Dobritzsch, D, Ivarsson, Y.
登録日2022-05-20
公開日2023-03-29
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.
Mol.Syst.Biol., 19, 2023

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