2KIE
A PH domain within OCRL bridges clathrin mediated membrane trafficking to phosphoinositide metabolis
Summary for 2KIE
| Entry DOI | 10.2210/pdb2kie/pdb |
| NMR Information | BMRB: 16271 |
| Descriptor | Inositol polyphosphate 5-phosphatase OCRL-1 (1 entity in total) |
| Functional Keywords | ocrl, inpp5b, ph, clathrin, endocytosis, alternative splicing, cataract, disease mutation, hydrolase |
| Biological source | Homo sapiens (human) |
| Cellular location | Endosome: Q01968 |
| Total number of polymer chains | 1 |
| Total formula weight | 13869.88 |
| Authors | Mao, Y.,Balkin, D.M.,Zoncu, R.,Erdmann, K.,Tomasini, L.,Hu, F.,Jin, M.M.,Hodsdon, M.E.,De Camilli, P. (deposition date: 2009-05-03, release date: 2009-07-21, Last modification date: 2022-03-16) |
| Primary citation | Mao, Y.,Balkin, D.M.,Zoncu, R.,Erdmann, K.S.,Tomasini, L.,Hu, F.,Jin, M.M.,Hodsdon, M.E.,De Camilli, P. A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism Embo J., 28:1831-1842, 2009 Cited by PubMed: 19536138DOI: 10.1038/emboj.2009.155 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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