PDB: 1957 件ウェブページステータス検索Chemie searchBIRD

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4XHA	Crystal structure of Thosea asigna virus RNA-dependent RNA polymerase (RdRP) complexed with Lu3+ 分子名称: GLYCEROL, LUTETIUM (III) ION, RNA-dependent RNA polymerase, ... 著者 Ferrero, D.S, Buxaderas, M, Rodriguez, J.F, Verdaguer, N. 登録日 2015-01-05 公開日 2015-11-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent Polymerases. Plos Pathog., 11, 2015
4XHI	Crystal structure of native Thosea asigna virus RNA-dependent RNA polymerase (RdRP) at 2.15 Angstrom resolution 分子名称: GLYCEROL, RNA-dependent RNA polymerase, SULFATE ION 著者 Ferrero, D.S, Buxaderas, M, Rodriguez, J.F, Verdaguer, N. 登録日 2015-01-05 公開日 2015-11-04 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The Structure of the RNA-Dependent RNA Polymerase of a Permutotetravirus Suggests a Link between Primer-Dependent and Primer-Independent Polymerases. Plos Pathog., 11, 2015
3UPF	Crystal structure of murine norovirus RNA-dependent RNA polymerase bound to NF023 分子名称: 8-({3-[({3-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)amino]benzoyl}amino)naphthalene-1,3,5-trisulfonic acid, RNA-dependent RNA polymerase, SULFATE ION 著者 Milani, M, Mastrangelo, E, Bolognesi, M. 登録日 2011-11-18 公開日 2012-05-02 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases. J.Mol.Biol., 419, 2012
4LQ9	Crystal structure of human norovirus RNA-dependent RNA-polymerase in complex with NAF2 分子名称: MAGNESIUM ION, RNA-dependent RNA-polymerase, naphthalene-1,5-disulfonic acid 著者 Milani, M, Tarantino, D, Mastrangelo, E, Croci, R. 登録日 2013-07-17 公開日 2014-02-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase. Antiviral Res., 102, 2014
4LQ3	Crystal structure of human norovirus RNA-dependent RNA-polymerase bound to the inhibitor PPNDS 分子名称: 3-[(E)-{4-formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]pyridin-2-yl}diazenyl]-7-nitronaphthalene-1,5-disulfonic acid, 5'-R(P*GP*G)-3', MAGNESIUM ION, ... 著者 Milani, M, Tarantino, D, Mastrangelo, E, Croci, R. 登録日 2013-07-17 公開日 2014-02-12 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase. Antiviral Res., 102, 2014
1WNE	Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with a template-primer RNA 分子名称: 5'-R(*CP*AP*UP*GP*GP*GP*CP*C)-3', 5'-R(*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2004-07-31 公開日 2004-08-31 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of Foot-and-Mouth Disease Virus RNA-dependent RNA Polymerase and Its Complex with a Template-Primer RNA J.Biol.Chem., 279, 2004
2PUS	Unprecedented activation mechanism of a non-canonical RNA-dependent RNA polymerase 分子名称: IBDV VP1 RNA-dependant RNA polymerase 著者 Garriga, D, Navarro, A, Querol-Audi, J, Abaitua, F, Rodriguez, J.F, Verdaguer, N. 登録日 2007-05-09 公開日 2007-11-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Activation mechanism of a noncanonical RNA-dependent RNA polymerase. Proc.Natl.Acad.Sci.Usa, 104, 2007
1S49	Crystal Structure of RNA-dependent RNA polymerase construct 1 (residues 71-679) from bovine viral diarrhea virus complexed with GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase 著者 Choi, K.H, Groarke, J.M, Young, D.C, Kuhn, R.J, Smith, J.L, Pevear, D.C, Rossmann, M.G. 登録日 2004-01-15 公開日 2004-04-06 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of the RNA-dependent RNA polymerase from bovine viral diarrhea virus establishes the role of GTP in de novo initiation. Proc.Natl.Acad.Sci.Usa, 101, 2004
4WFZ	Coxsackievirus B3 3Dpol RNA Dependent RNA Polymerase - NaCl Crystal Form 分子名称: RNA-directed RNA polymerase, SODIUM ION 著者 Peersen, O.B, McDonald, S.M. 登録日 2014-09-17 公開日 2014-10-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.803 Å) 主引用文献 Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases. J.Virol., 89, 2015
4WFX	Coxsackievirus B3 Polymerase - F232L Mutant - NaCl Crystal Form 分子名称: RNA-directed RNA polymerase, SODIUM ION 著者 Peersen, O.B, McDonald, S.M. 登録日 2014-09-17 公開日 2014-10-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.808 Å) 主引用文献 Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases. J.Virol., 89, 2015
2CKW	The 2.3 A resolution structure of the Sapporo virus RNA dependant RNA polymerase. 分子名称: RNA-DIRECTED RNA POLYMERASE 著者 Fullerton, S.W.B, Tucker, P.A, Rohayem, J, Coutard, B, Gebhardt, J, Gorbalenya, A, Canard, B. 登録日 2006-04-24 公開日 2006-11-29 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and Functional Characterization of Sapovirus RNA-Dependent RNA Polymerase. J.Virol., 81, 2007
2JL9	Structural explanation for the role of Mn in the activity of phi6 RNA- dependent RNA polymerase 分子名称: RNA-DIRECTED RNA POLYMERASE 著者 Poranen, M.M, Salgado, P.S, Koivunen, M.R.L, Wright, S, Bamford, D.H, Stuart, D.I, Grimes, J.M. 登録日 2008-09-05 公開日 2008-11-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Explanation for the Role of Mn2+ in the Activity of {Phi}6 RNA-Dependent RNA Polymerase. Nucleic Acids Res., 36, 2008
2IJF	Crystal Structure of the Poliovirus RNA-Dependent RNA Polymerase Fidelity Mutant 3Dpol G64S 分子名称: RNA-directed RNA polymerase 著者 Marcotte, L.L, Gohara, D.G, Filman, D.J, Hogle, J.M. 登録日 2006-09-29 公開日 2007-02-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of poliovirus 3CD: virally-encoded protease and precursor to the RNA-dependent RNA polymerase. J.Virol., 81, 2007
2EC0	RNA-dependent RNA polymerase of foot-and-mouth disease virus in complex with a template-primer RNA and ATP 分子名称: 5'-R(*GP*GP*GP*CP*CP*CP*A)-3', 5'-R(P*AP*UP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2007-02-09 公開日 2007-06-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
2D7S	Foot and Mouth Disease Virus RNA-dependent RNA polymerase in complex with VPg protein 分子名称: RNA-dependent RNA polymerase, VPg1 protein 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2005-11-29 公開日 2006-03-28 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structure of a protein primer-polymerase complex in the initiation of genome replication Embo J., 25, 2006
7W88	CryoEM structure of open form ZmRDR2 at 3.5 Angstroms resolution 分子名称: RNA-dependent RNA polymerase 著者 Du, X, Yang, Z, Du, J. 登録日 2021-12-07 公開日 2022-06-08 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of plant RNA-DEPENDENT RNA POLYMERASE 2, an enzyme involved in small interfering RNA production. Plant Cell, 34, 2022
7W84	CryoEM structure of apo form ZmRDR2 at 3.4 Angstroms resolution 分子名称: RNA-dependent RNA polymerase 著者 Du, X, Yang, Z, Du, J. 登録日 2021-12-07 公開日 2022-06-08 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of plant RNA-DEPENDENT RNA POLYMERASE 2, an enzyme involved in small interfering RNA production. Plant Cell, 34, 2022
7W82	Crystal structure of maize RDR2 分子名称: RNA-dependent RNA polymerase 著者 Du, X, Yang, Z, Du, J. 登録日 2021-12-07 公開日 2022-06-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of plant RNA-DEPENDENT RNA POLYMERASE 2, an enzyme involved in small interfering RNA production. Plant Cell, 34, 2022
4OOW	HCV NS5B polymerase with a fragment of quercetagetin 分子名称: CATECHOL, RNA-directed RNA polymerase 著者 Guichou, J.F, Ahmed-Belkacem, A, Rozenn, B, Nazim, N, Hernandez, E, Pallier, C, Pawlotsky, J.M. 登録日 2014-02-04 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Inhibition of RNA binding to hepatitis C virus RNA-dependent RNA polymerase: a new mechanism for antiviral intervention. Nucleic Acids Res., 42, 2014
8FPJ	Co-structure of the Human Metapneunomovirus RNA-dependent RNA polymerase with MRK-1 分子名称: 4-(2-aminopropan-2-yl)-N'-[4-(cyclopropyloxy)-3-methoxybenzoyl]-6-(4-fluorophenyl)pyridine-2-carbohydrazide, Phosphoprotein, RNA-directed RNA polymerase L 著者 Fischmann, T.O. 登録日 2023-01-04 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.74 Å) 主引用文献 Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases. Commun Biol, 6, 2023
6KWR	Crystal structure of enterovirus 71 polymerase elongation complex (ddCTP form) 分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, MAGNESIUM ION, RNA (31-MER), ... 著者 Shi, W, Gong, P. 登録日 2019-09-08 公開日 2019-12-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A nucleobase-binding pocket in a viral RNA-dependent RNA polymerase contributes to elongation complex stability. Nucleic Acids Res., 48, 2020
8FPI	Co-structure of the Respiratory Syncytial Virus RNA-dependent RNA polymerase with MRK-1 分子名称: 4-(2-aminopropan-2-yl)-N'-[4-(cyclopropyloxy)-3-methoxybenzoyl]-6-(4-fluorophenyl)pyridine-2-carbohydrazide, Phosphoprotein, RNA-directed RNA polymerase L 著者 Fischmann, T.O. 登録日 2023-01-04 公開日 2023-06-14 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.52 Å) 主引用文献 Conserved allosteric inhibitory site on the respiratory syncytial virus and human metapneumovirus RNA-dependent RNA polymerases. Commun Biol, 6, 2023
4WFY	Coxsackievirus B3 Polymerase - F232L Mutant - AmSO4 Crystal Form 分子名称: GLYCEROL, RNA-directed RNA polymerase, SULFATE ION 著者 Peersen, O.B, McDonald, S.M. 登録日 2014-09-17 公開日 2014-10-22 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases. J.Virol., 89, 2015
6LD2	Zika NS5 polymerase domain 分子名称: (1S,2S,4S,5R)-2,4-dimethoxy-5-thiophen-2-yl-cyclohexane-1-carboxylic acid, RNA-directed RNA polymerase NS5, ZINC ION 著者 El Sahili, A, Lescar, J. 登録日 2019-11-20 公開日 2020-08-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase. J.Virol., 94, 2020
6LD1	Zika NS5 polymerase domain 分子名称: 1,2-ETHANEDIOL, RNA-directed RNA polymerase NS5, ZINC ION 著者 El Sahili, A, Lescar, J. 登録日 2019-11-20 公開日 2020-08-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase. J.Virol., 94, 2020

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