2FF1
Crystal structure of Trypanosoma vivax nucleoside hydrolase soaked with ImmucillinH
Summary for 2FF1
| Entry DOI | 10.2210/pdb2ff1/pdb |
| Related | 1HOZ 1HP0 1KIC 1KIE 1R4F 2MAS |
| Descriptor | IAG-nucleoside hydrolase, CALCIUM ION, 1,4-DIDEOXY-4-AZA-1-(S)-(9-DEAZAHYPOXANTHIN-9-YL)-D-RIBITOL, ... (4 entities in total) |
| Functional Keywords | rossmann fold, disordered loops, aromatic stacking, hydrolase |
| Biological source | Trypanosoma vivax |
| Total number of polymer chains | 2 |
| Total formula weight | 76050.63 |
| Authors | Versees, W.,Barlow, J.,Steyaert, J. (deposition date: 2005-12-18, release date: 2006-05-23, Last modification date: 2022-10-05) |
| Primary citation | Versees, W.,Barlow, J.,Steyaert, J. Transition-state Complex of the Purine-specific Nucleoside Hydrolase of T.vivax: Enzyme Conformational Changes and Implications for Catalysis. J.Mol.Biol., 359:331-346, 2006 Cited by PubMed: 16630632DOI: 10.1016/j.jmb.2006.03.026 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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