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8PQW
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BU of 8pqw by Molmil
Cytoplasmic dynein-1 motor domain bound to dynactin-p150glued and LIS1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ...
著者Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P.
登録日2023-07-12
公開日2024-03-27
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
8PR2
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BU of 8pr2 by Molmil
Cytoplasmic dynein-1 heavy chain bound to JIP3-LZI
分子名称: C-Jun-amino-terminal kinase-interacting protein 3, Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, ...
著者Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P.
登録日2023-07-12
公開日2024-03-27
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Molecular mechanism of dynein-dynactin complex assembly by LIS1.
Science, 383, 2024
7KZM
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BU of 7kzm by Molmil
Outer dynein arm bound to doublet microtubules from C. reinhardtii
分子名称: DC1, DC2, Dynein 11 kDa light chain, ...
著者Walton, T, Wu, H, Brown, A.B.
登録日2020-12-10
公開日2021-01-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (7.5 Å)
主引用文献Structure of a microtubule-bound axonemal dynein.
Nat Commun, 12, 2021
7KZN
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BU of 7kzn by Molmil
Outer dynein arm core subcomplex from C. reinhardtii
分子名称: DC1, DC2, Dynein 11 kDa light chain, ...
著者Walton, T, Wu, H, Brown, A.B.
登録日2020-12-10
公開日2021-01-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure of a microtubule-bound axonemal dynein.
Nat Commun, 12, 2021
7KZO
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BU of 7kzo by Molmil
Outer dynein arm docking complex bound to doublet microtubules from C. reinhardtii
分子名称: Dynein gamma chain, flagellar outer arm, GUANOSINE-5'-DIPHOSPHATE, ...
著者Walton, T, Wu, H, Brown, A.B.
登録日2020-12-10
公開日2021-01-20
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of a microtubule-bound axonemal dynein.
Nat Commun, 12, 2021
7KEK
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BU of 7kek by Molmil
Structure of the free outer-arm dynein in pre-parallel state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein alpha heavy chain, ...
著者Rao, Q, Zhang, K.
登録日2020-10-11
公開日2021-09-29
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Structures of outer-arm dynein array on microtubule doublet reveal a motor coordination mechanism.
Nat.Struct.Mol.Biol., 28, 2021
7MI3
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BU of 7mi3 by Molmil
Signal subtracted reconstruction of AAA2, AAA3, and AAA4 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 4
分子名称: (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ...
著者Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M.
登録日2021-04-16
公開日2021-05-26
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
7MI6
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BU of 7mi6 by Molmil
Yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound, Model 1
分子名称: (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ...
著者Santarossa, C.C, Urnavicius, L, Coudray, N, Ekeirt, D.C, Bhabha, G, Kapoor, T.M.
登録日2021-04-16
公開日2021-05-26
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
7MI1
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BU of 7mi1 by Molmil
X-ray structure of yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound (compound 20)
分子名称: Chimera protein of Dynein and Endolysin
著者Santarossa, C.C, Ekiert, D.C, Bhabha, G, Kapoor, T.M.
登録日2021-04-16
公開日2021-05-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (4.5 Å)
主引用文献Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
7MI8
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BU of 7mi8 by Molmil
Signal subtracted reconstruction of AAA5 and AAA6 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 5
分子名称: Fusion protein of Dynein and Endolysin
著者Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M.
登録日2021-04-16
公開日2021-05-26
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
7MGM
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BU of 7mgm by Molmil
Structure of yeast cytoplasmic dynein with AAA3 Walker B mutation bound to Lis1
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Lahiri, I, Reimer, J.M, Leschziner, A.E.
登録日2021-04-12
公開日2022-01-19
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structural basis for cytoplasmic dynein-1 regulation by Lis1.
Elife, 11, 2022
7MOQ
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BU of 7moq by Molmil
The structure of the Tetrahymena thermophila outer dynein arm on doublet microtubule
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Docking complex 1 protein, ...
著者Kubo, S, Yang, S.K, Ichikawa, M, Bui, K.H.
登録日2021-05-03
公開日2021-07-14
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (8 Å)
主引用文献Remodeling and activation mechanisms of outer arm dyneins revealed by cryo-EM.
Embo Rep., 22, 2021
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件を2024-10-16に公開中

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