PDB: 315 件ウェブページステータス検索Chemie searchBIRD

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7RRL	Alternate Crystal Form of Human Malate Dehydrogenase I 分子名称: Malate dehydrogenase, cytoplasmic 著者 McCue, W, Finzel, B.C. 登録日 2021-08-09 公開日 2022-02-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural Studies to Enable Drug Discovery Ph.D.Thesis,University of Minnesota, 2021
4ND3	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (l-lactic acid) and cofactor (b-nicotinamide adenine dinucleotide) 分子名称: (2S)-2-HYDROXYPROPANOIC ACID, GLYCEROL, Lactate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
4ND4	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (pyruvic acid) and cofactor (b-nicotinamide adenine dinucleotide) 分子名称: GLYCEROL, Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
4ND2	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (pyruvic acid) and cofactor analog (3-acetylpyridine adenine dinucleotide) 分子名称: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, GLYCEROL, Lactate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
4ND1	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with cofactor (b-nicotinamide adenine dinucleotide) and inhibitor (oxamic acid) 分子名称: GLYCEROL, Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
4ND5	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum 分子名称: Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
6IHD	Crystal structure of Malate dehydrogenase from Metallosphaera sedula 分子名称: 2-ETHOXYETHANOL, Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Lee, D, Kim, K.J. 登録日 2018-09-29 公開日 2019-02-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure and biochemical characterization of malate dehydrogenase from Metallosphaera sedula Biochem. Biophys. Res. Commun., 509, 2019
6IHE	Crystal structure of Malate dehydrogenase from Metallosphaera sedula 分子名称: 1,2-ETHANEDIOL, D-MALATE, DI(HYDROXYETHYL)ETHER, ... 著者 Lee, D, Kim, K.J. 登録日 2018-09-29 公開日 2019-02-06 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure and biochemical characterization of malate dehydrogenase from Metallosphaera sedula Biochem. Biophys. Res. Commun., 509, 2019
6K13	Crystal Structure Basis for BmLDH Complex 分子名称: L-lactate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID 著者 Long, Y, Shen, Z. 登録日 2019-05-09 公開日 2019-10-16 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Crystal structures ofBabesia microtilactate dehydrogenase BmLDH reveal a critical role for Arg99 in catalysis. Faseb J., 33, 2019
4LMR	Crystal structure of L-lactate dehydrogenase from Bacillus cereus ATCC 14579, NYSGRC Target 029452 分子名称: L-lactate dehydrogenase 1 著者 Malashkevich, V.N, Bonanno, J.B, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-07-10 公開日 2013-07-31 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Crystal structure of L-lactate dehydrogenase from Bacillus cereus ATCC 14579, NYSGRC Target 029452 To be Published
7EPM	human LDHC complexed with NAD+ and ethylamino acetic acid 分子名称: 2-(ethylamino)-2-oxidanylidene-ethanoic acid, L-lactate dehydrogenase C chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Yu, Y, Chen, Q. 登録日 2021-04-27 公開日 2022-03-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Identification of human LDHC4 as a potential target for anticancer drug discovery. Acta Pharm Sin B, 12, 2022
4LN1	CRYSTAL STRUCTURE OF L-lactate dehydrogenase from Bacillus cereus ATCC 14579 complexed with calcium, NYSGRC Target 029452 分子名称: CALCIUM ION, L-lactate dehydrogenase 1 著者 Malashkevich, V.N, Bonanno, J.B, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-07-11 公開日 2013-07-24 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of L-lactate dehydrogenase from Bacillus cereus ATCC 14579 complexed with calcium, NYSGRC Target 029452 To be Published
4UUO	Apo Trichomonas vaginalis malate dehydrogenase 分子名称: CYTOSOLIC MALATE DEHYDROGENASE 著者 Steindel, P.A, Chen, E.H, Theobald, D.L. 登録日 2014-07-29 公開日 2015-08-12 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.842 Å) 主引用文献 Gradual Neofunctionalization in the Convergent Evolution of Trichomonad Lactate and Malate Dehydrogenases. Protein Sci., 25, 2016
9LDT	DESIGN AND SYNTHESIS OF NEW ENZYMES BASED ON THE LACTATE DEHYDROGENASE FRAMEWORK 分子名称: LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID, ... 著者 Dunn, C.R, Holbrook, J.J, Muirhead, H. 登録日 1991-11-26 公開日 1993-10-31 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Design and synthesis of new enzymes based on the lactate dehydrogenase framework. Philos.Trans.R.Soc.London,Ser.B, 332, 1991
9LDB	DESIGN AND SYNTHESIS OF NEW ENZYMES BASED ON THE LACTATE DEHYDROGENASE FRAMEWORK 分子名称: LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, OXAMIC ACID, ... 著者 Dunn, C.R, Holbrook, J.J, Muirhead, H. 登録日 1991-11-26 公開日 1993-10-31 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Design and synthesis of new enzymes based on the lactate dehydrogenase framework. Philos.Trans.R.Soc.London,Ser.B, 332, 1991
4WLF	Crystal structure of L-malate bound MDH2 分子名称: (2S)-2-hydroxybutanedioic acid, Malate dehydrogenase, mitochondrial, ... 著者 Eo, Y.M, Han, B.G, Ahn, H.C. 登録日 2014-10-07 公開日 2015-11-25 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of L-malate bound MDH2 To Be Published
7P4G	Rabbit Muscle L-lactate dehydrogenase in complex with citrate 分子名称: CITRIC ACID, L-lactate dehydrogenase A chain 著者 Iacovino, L.G, Binda, C, Hochkoeppler, A. 登録日 2021-07-11 公開日 2022-05-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Allosteric transitions of rabbit skeletal muscle lactate dehydrogenase induced by pH-dependent dissociation of the tetrameric enzyme. Biochimie, 199, 2022
2ZQZ	R-state structure of allosteric L-lactate dehydrogenase from Lactobacillus casei 分子名称: L-lactate dehydrogenase, SULFATE ION 著者 Arai, K, Ishimitsu, T, Fushinobu, S, Uchikoba, H, Matsuzawa, H, Taguchi, H. 登録日 2008-08-22 公開日 2009-09-08 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Active and inactive state structures of unliganded Lactobacillus casei allosteric L-lactate dehydrogenase. Proteins, 78, 2010
9BK3	Crystal structure of Lactate dehydrogenase in complex with 4-((4-(1-methyl-1H-imidazole-2-carbonyl)phenyl)amino)-4-oxo-2-(4-(trifluoromethyl)phenyl)butanoic acid (R-enantiomer, orthorhombic P form) 分子名称: (2R)-4-[4-(1-methyl-1H-imidazole-2-carbonyl)anilino]-4-oxo-2-[4-(trifluoromethyl)phenyl]butanoic acid, CHLORIDE ION, L-lactate dehydrogenase A chain, ... 著者 Lovell, S, Cooper, A, Battaile, K.P, Sharma, H. 登録日 2024-04-26 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Synthesis and biological characterization of an orally bioavailable lactate dehydrogenase-A inhibitor against pancreatic cancer. Eur.J.Med.Chem., 275, 2024
8RS5	Crystal structure of Methanopyrus kandleri malate dehydrogenase mutant 4 分子名称: CHLORIDE ION, Malate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... 著者 Coquille, S, Engilberge, S, Madern, D. 登録日 2024-01-24 公開日 2024-07-10 最終更新日 2025-01-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Allostery and Evolution: A Molecular Journey Through the Structural and Dynamical Landscape of an Enzyme Super Family. Mol.Biol.Evol., 42, 2025
8RWL	Crystal structure of Methanopyrus kandleri malate dehydrogenase mutant 1 分子名称: CHLORIDE ION, GLYCEROL, Malate dehydrogenase, ... 著者 Coquille, S, Roche, J, Engilberge, S, Girard, E, Madern, D. 登録日 2024-02-05 公開日 2024-07-10 最終更新日 2025-01-29 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Allostery and Evolution: A Molecular Journey Through the Structural and Dynamical Landscape of an Enzyme Super Family. Mol.Biol.Evol., 42, 2025
9BK2	Crystal structure of Lactate dehydrogenase in complex with 4-((4-(1-methyl-1H-imidazole-2-carbonyl)phenyl)amino)-4-oxo-2-(4-(trifluoromethyl)phenyl)butanoic acid (S-enantiomer, monoclinic P form) 分子名称: (2S)-4-[4-(1-methyl-1H-imidazole-2-carbonyl)anilino]-4-oxo-2-[4-(trifluoromethyl)phenyl]butanoic acid, DIMETHYL SULFOXIDE, L-lactate dehydrogenase A chain, ... 著者 Lovell, S, Cooper, A, Battaile, K.P, Sharma, H. 登録日 2024-04-26 公開日 2024-07-10 最終更新日 2024-09-04 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Synthesis and biological characterization of an orally bioavailable lactate dehydrogenase-A inhibitor against pancreatic cancer. Eur.J.Med.Chem., 275, 2024
7RM9	Human Malate Dehydrogenase I (MDHI) 分子名称: MALONATE ION, Malate dehydrogenase, cytoplasmic 著者 McCue, W, Finzel, B.C. 登録日 2021-07-27 公開日 2022-01-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural Characterization of the Human Cytosolic Malate Dehydrogenase I. Acs Omega, 7, 2022
3DL2	Hexagonal structure of the LDH domain of Human Ubiquitin-conjugating Enzyme E2-like Isoform A 分子名称: PHOSPHATE ION, SODIUM ION, Ubiquitin-conjugating enzyme E2 variant 3 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Finerty Jr, P.J, Butler-Cole, C, Bountra, C, Wolkstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2008-06-26 公開日 2008-07-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Investigation Into the L-Lactate Dehydrogenase Domain of Human Ubiquitin-Conjugating Enzyme E2-Like Isoform A. To be Published
2PWZ	Crystal structure of the apo form of E.Coli malate dehydrogenase 分子名称: Malate dehydrogenase 著者 Soderberg, C.A.G, Clarke, T.A, Richardson, D.J, Hemmings, A.M. 登録日 2007-05-14 公開日 2007-05-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The X-ray crystal structure of the apo form of E.Coli malate dehydrogenase in space group C2 To be Published

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