8RS5

Crystal structure of Methanopyrus kandleri malate dehydrogenase mutant 4

Summary for 8RS5

• Entry DOI: 10.2210/pdb8rs5/pdb
• Descriptor: Malate dehydrogenase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: malate dehydrogenase, rossmann-like motif, nad(p)h binding site, oxidoreductase
• Biological source: Methanopyrus kandleri
• Total number of polymer chains: 2
• Total formula weight: 70981.17

Authors

Coquille, S.,Engilberge, S.,Madern, D. (deposition date: 2024-01-24, release date: 2024-07-10)

• Primary citation: Coquille, S.,Simoes Pereira, C.,Brochier-Armanet, C.,Roche, J.,Santoni, G.,Coquelle, N.,Girard, E.,Sterpone, F.,Madern, D.; Navigating the conformational landscape of an enzyme. Stabilization of a low populated conformer by evolutionary mutations triggers Allostery into a non-allosteric enzyme.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)