PDB: 107 件ウェブページステータス検索Chemie searchBIRD

---

4JAR	Crystal structure of mycobacterium tuberculosis pks11 in complex with polyketide intermediates and evidence that it synthesize ALKYLPYRONES 分子名称: Alpha-pyrone synthesis polyketide synthase-like Pks11 著者 Gokulan, K, Sacchettini, J.C, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) 登録日 2013-02-19 公開日 2013-04-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones. J.Biol.Chem., 288, 2013
3VS9	Crystal structure of type III PKS ArsC mutant 分子名称: SODIUM ION, TETRAETHYLENE GLYCOL, Type III polyketide synthase 著者 Satou, R, Miyanaga, A, Ozawa, H, Funa, N, Miyazono, K, Tanokura, M, Ohnishi, Y, Horinouchi, S. 登録日 2012-04-23 公開日 2013-04-24 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Structural basis for cyclization specificity of two Azotobacter type III polyketide synthases: a single amino acid substitution reverses their cyclization specificity J.Biol.Chem., 288, 2013
8B35	Chalcone synthase from Hordeum vulgare complexed with CoA and naringenin 分子名称: COENZYME A, Chalcone synthase 2, NARINGENIN 著者 Zhang, L, Groves, M.R. 登録日 2022-09-15 公開日 2023-09-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Engineering a Plant Polyketide Synthase for the Biosynthesis of Methylated Flavonoids. J.Agric.Food Chem., 72, 2024
8B3C	Chalcone synthase from Hordeum vulgare complexed with CoA and eriodictyol 分子名称: (2S)-2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE, COENZYME A, Chalcone synthase 2 著者 Zhang, L, Groves, M.R. 登録日 2022-09-16 公開日 2023-09-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Engineering a Plant Polyketide Synthase for the Biosynthesis of Methylated Flavonoids. J.Agric.Food Chem., 72, 2024
6L73	Quinolone synthase (AmQNS) from Aegle marmelos Correa 分子名称: Type III polyketide synthase 著者 Mallika, V, Abhinav, K.V, Soniya, E.V. 登録日 2019-10-30 公開日 2020-11-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Quinolone synthase from Aegle marmelos Correa, Dimer To Be Published
3EUT	X-ray crystal structure of a type III pentaketide synthase from Neurospora crassa 分子名称: Putative uncharacterized protein, icosanoic acid 著者 Zhang, H, Brunzelle, J.S, Nair, S.K. 登録日 2008-10-10 公開日 2008-11-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Distinct Structural Elements Dictate the Specificity of the Type III Pentaketide Synthase from Neurospora crassa. Chem.Biol., 15, 2008
1D6I	CHALCONE SYNTHASE (H303Q MUTANT) 分子名称: CHALCONE SYNTHASE, SULFATE ION 著者 Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P. 登録日 1999-10-13 公開日 2000-02-03 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. Biochemistry, 39, 2000
1XET	Crystal structure of stilbene synthase from Pinus sylvestris, complexed with methylmalonyl CoA 分子名称: 3-(1H-INDOL-3-YL)-2-OXOPROPANOIC ACID, Dihydropinosylvin synthase, METHYLMALONYL-COENZYME A 著者 Ng, S.H, Chirgadze, D, Spiteller, D, Li, T.L, Spencer, J.B, Blundell, T.L. 登録日 2004-09-12 公開日 2006-04-11 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of stilbene synthase from Pinus sylvestris, complexed with methylmalonyl CoA To be Published
3AWK	Crystal structure of the polyketide synthase 1 from huperzia serrata 分子名称: Chalcone synthase-like polyketide synthase, GLYCEROL, SULFATE ION 著者 Morita, H, Kondo, S, Kato, R, Sugio, S, Kohno, T, Abe, I. 登録日 2011-03-23 公開日 2011-08-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase. Proc.Natl.Acad.Sci.USA, 108, 2011
3OIT	Crystal structure of curcuminoid synthase CUS from Oryza sativa 分子名称: Os07g0271500 protein 著者 Miyazono, K, Um, J, Imai, F.L, Katsuyama, Y, Ohnishi, Y, Horinouchi, S, Tanokura, M. 登録日 2010-08-19 公開日 2010-10-20 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of curcuminoid synthase CUS from Oryza sativa Proteins, 79, 2011
1U0W	An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: 18xCHS+resveratrol Structure 分子名称: Chalcone synthase 2, RESVERATROL 著者 Austin, M.B, Bowman, M.E, Ferrer, J.-L, Schroder, J, Noel, J.P. 登録日 2004-07-14 公開日 2004-10-12 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases Chem.Biol., 11, 2004
3WY0	The I375W mutant of CsyB complexed with CoA-SH 分子名称: COENZYME A, Putative uncharacterized protein csyB 著者 Mori, T, Yang, D, Matsui, T, Morita, H, Fujii, I, Abe, I. 登録日 2014-08-13 公開日 2015-01-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Structural basis for the formation of acylalkylpyrones from two beta-ketoacyl units by the fungal type III polyketide synthase CsyB. J.Biol.Chem., 290, 2015
6DXA	Crystal structure of chalcone synthase from Pinus sylvestris 分子名称: Chalcone synthase 著者 Liou, G, Chiang, Y.C, Wang, Y, Weng, J.K. 登録日 2018-06-28 公開日 2018-10-17 最終更新日 2019-11-27 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Mechanistic basis for the evolution of chalcone synthase catalytic cysteine reactivity in land plants. J. Biol. Chem., 293, 2018
4JAO	Crystal Structure of Mycobacterium tuberculosis PKS11 Reveals Intermediates in the Synthesis of Methyl-branched Alkylpyrones 分子名称: (2S)-2-methylheptadecan-1-ol, Alpha-pyrone synthesis polyketide synthase-like Pks11, PALMITIC ACID 著者 Gokulan, K, Sacchettini, J.C, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB) 登録日 2013-02-18 公開日 2013-04-24 最終更新日 2013-11-27 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones. J.Biol.Chem., 288, 2013
1EE0	2-PYRONE SYNTHASE COMPLEXED WITH ACETOACETYL-COA 分子名称: 2-PYRONE SYNTHASE, ACETOACETYL-COENZYME A 著者 Jez, J.M, Austin, M.B, Ferrer, J, Bowmann, M.E, Schroeder, J, Noel, J.P. 登録日 2000-01-28 公開日 2001-01-31 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural control of polyketide formation in plant-specific polyketide synthases. Chem.Biol., 7, 2000
7W6G	TKS-L190G mutant from Cannabis sativa in complex with lauroyl-CoA 分子名称: 3,5,7-trioxododecanoyl-CoA synthase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Nakashima, Y, Lee, Y.E, Morita, H. 登録日 2021-12-01 公開日 2022-02-02 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Dual Engineering of Olivetolic Acid Cyclase and Tetraketide Synthase to Generate Longer Alkyl-Chain Olivetolic Acid Analogs. Org.Lett., 24, 2022
1QLV	Pyrone synthase (PYS) from Gerbera hybrida 分子名称: PYRONE SYNTHASE 著者 Ferrer, J.-L, Jez, J.M, Bowman, M.E, Schroder, J, Noel, J.P. 登録日 1999-09-16 公開日 2000-09-24 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Pyrone Synthase (Pys) from Gerbera Hybrida To be Published
3EUQ	X-ray structural of a type III pentaketide synthase from Neurospora crassa 分子名称: HEXAETHYLENE GLYCOL, Putative uncharacterized protein 著者 Zhang, H, Brunzelle, J.S, Nair, S.K. 登録日 2008-10-10 公開日 2008-11-11 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Distinct Structural Elements Dictate the Specificity of the Type III Pentaketide Synthase from Neurospora crassa. Chem.Biol., 15, 2008
5UC5	Chalcone synthase from Malus domestica 分子名称: CHS2 chalcone synthase 著者 Stewart Jr, C.E, Noel, J.P. 登録日 2016-12-21 公開日 2017-12-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.102 Å) 主引用文献 Molecular architectures of benzoic acid-specific type III polyketide synthases. Acta Crystallogr D Struct Biol, 73, 2017
1U0U	An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: Pine stilbene synthase structure 分子名称: Dihydropinosylvin synthase 著者 Austin, M.B, Bowman, M.E, Ferrer, J.-L, Schroder, J, Noel, J.P. 登録日 2004-07-14 公開日 2004-10-12 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases Chem.Biol., 11, 2004
8V8N	Switchgrass Chalcone Synthase C170S 分子名称: Chalcone synthase, GLYCEROL 著者 Lewis, J.A, Kang, C. 登録日 2023-12-05 公開日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Structural and Interactional Analysis of the Flavonoid Pathway Proteins: Chalcone Synthase, Chalcone Isomerase and Chalcone Isomerase-like Protein Int J Mol Sci, 25, 2024
1D6H	CHALONE SYNTHASE (N336A MUTANT COMPLEXED WITH COA) 分子名称: CHALCONE SYNTHASE, COENZYME A, SULFATE ION 著者 Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P. 登録日 1999-10-13 公開日 2000-02-03 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase. Biochemistry, 39, 2000
7FFH	Diarylpentanoid-producing polyketide synthase (N199L mutant) 分子名称: Type III polyketide synthase 著者 Morita, H, Wong, C.P, Liu, Q, Takeshi, K, Lee, Y, Nakashima, Y. 登録日 2021-07-23 公開日 2022-01-19 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood. Nat Commun, 13, 2022
3AWJ	Crystal structure of the Huperzia serrata polyketide synthase 1 complexed with CoA-SH 分子名称: COENZYME A, Chalcone synthase-like polyketide synthase, SULFATE ION 著者 Morita, H, Kondo, S, Kato, R, Sugio, S, Kohno, T, Abe, I. 登録日 2011-03-23 公開日 2011-08-31 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Synthesis of unnatural alkaloid scaffolds by exploiting plant polyketide synthase. Proc.Natl.Acad.Sci.USA, 108, 2011
5WX4	Alkylquinolone synthase from Evodia rutaecarpa 分子名称: alkylquinolone synthase 著者 Matsui, T, Kodama, T, Tadakoshi, T, Morita, H. 登録日 2017-01-06 公開日 2017-04-26 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.203 Å) 主引用文献 2-Alkylquinolone alkaloid biosynthesis in the medicinal plant Evodia rutaecarpa involves collaboration of two novel type III polyketide synthases J. Biol. Chem., 292, 2017

<12345>