PDB: 125 件ウェブページステータス検索Chemie searchBIRD

---

5FVE	Crystal Structure of Helicobacter pylori beta clamp in complex with 3, 4-Difluorobenzamide 分子名称: 3,4-difluorobenzamide, DNA POLYMERASE III SUBUNIT BETA 著者 Pandey, P, Gourinath, S. 登録日 2016-02-05 公開日 2017-02-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Screening of E. coli beta-clamp Inhibitors Revealed that Few Inhibit Helicobacter pylori More Effectively: Structural and Functional Characterization. Antibiotics (Basel), 7, 2018
3D1G	Structure of a small molecule inhibitor bound to a DNA sliding clamp 分子名称: DNA polymerase III subunit beta, [(5R)-5-(2,3-dibromo-5-ethoxy-4-hydroxybenzyl)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]acetic acid 著者 Georgescu, R.E, Yurieva, O, Seung-Sup, K, Kuriyan, J, Kong, X.-P, O'Donnell, M. 登録日 2008-05-05 公開日 2008-07-29 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp. Proc.Natl.Acad.Sci.Usa, 105, 2008
5AH4	The sliding clamp of Mycobacterium smegmatis in complex with a natural product. 分子名称: CYCLOHEXYL GRISELIMYCIN, DNA POLYMERASE III SUBUNIT BETA, SODIUM ION 著者 Lukat, P, Kling, A, Heinz, D.W, Mueller, R. 登録日 2015-02-04 公開日 2015-06-03 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.313 Å) 主引用文献 Antibiotics. Targeting Dnan for Tuberculosis Therapy Using Novel Griselimycins. Science, 348, 2015
5G48	H.pylori Beta clamp in complex with Diflunisal 分子名称: 5-(2,4-DIFLUOROPHENYL)-2-HYDROXY-BENZOIC ACID, DNA POLYMERASE III SUBUNIT BETA 著者 Pandey, P, Gourinath, S. 登録日 2016-05-06 公開日 2017-06-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Targeting the beta-clamp in Helicobacter pylori with FDA-approved drugs reveals micromolar inhibition by diflunisal. FEBS Lett., 591, 2017
8GIZ	E. coli clamp loader with open clamp 分子名称: Beta sliding clamp, DNA polymerase III subunit delta, DNA polymerase III subunit delta', ... 著者 Oakley, A.J, Xu, Z.-Q, Dixon, N.E. 登録日 2023-03-14 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Structural characterisation of the complete cycle of sliding clamp loading in E. coli To Be Published
8GIY	E. coli clamp loader with closed clamp 分子名称: Beta sliding clamp, DNA polymerase III subunit delta, DNA polymerase III subunit delta', ... 著者 Oakley, A.J, Xu, Z.-Q, Dixon, N.E. 登録日 2023-03-14 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural characterisation of the complete cycle of sliding clamp loading in E. coli To Be Published
8GJ1	E. coli clamp loader with open clamp on primed template DNA (form 2) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Beta sliding clamp, DNA polymerase III subunit delta, ... 著者 Oakley, A.J, Xu, Z.-Q, Dixon, N.E. 登録日 2023-03-14 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural characterisation of the complete cycle of sliding clamp loading in E. coli To Be Published
8GJ2	E. coli clamp loader with closed clamp on primed template DNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, Beta sliding clamp, DNA polymerase III subunit delta, ... 著者 Oakley, A.J, Xu, Z.-Q, Dixon, N.E. 登録日 2023-03-14 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural characterisation of the complete cycle of sliding clamp loading in E. coli To Be Published
8GJ0	E. coli clamp loader with open clamp on primed template DNA (form 1) 分子名称: ADENOSINE-5'-DIPHOSPHATE, Beta sliding clamp, DNA polymerase III subunit delta, ... 著者 Oakley, A.J, Xu, Z.-Q, Dixon, N.E. 登録日 2023-03-14 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural characterisation of the complete cycle of sliding clamp loading in E. coli To Be Published
4N95	E. coli sliding clamp in complex with 5-chloroindoline-2,3-dione 分子名称: 5-chloro-1H-indole-2,3-dione, CALCIUM ION, CHLORIDE ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-10-19 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
4N94	E. coli sliding clamp in complex with 3,4-difluorobenzamide 分子名称: 1,2-ETHANEDIOL, 3,4-difluorobenzamide, CALCIUM ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-10-19 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
4N98	E. coli sliding clamp in complex with 4'-fluorobiphenyl-4-carboxylic acid 分子名称: 4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID, CALCIUM ION, CHLORIDE ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-10-19 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
6E8D	Crystal structure of the Bacillus subtilis sliding clamp-MutL complex. 分子名称: Beta sliding clamp,DNA mismatch repair protein MutL, GLYCEROL 著者 Guarne, A, Almawi, A.W. 登録日 2018-07-28 公開日 2019-05-01 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.34 Å) 主引用文献 Binding of the regulatory domain of MutL to the sliding beta-clamp is species specific. Nucleic Acids Res., 47, 2019
6E8E	Crystal structure of the Escherichia coli sliding clamp-MutL complex. 分子名称: Beta sliding clamp,DNA mismatch repair protein MutL, GLYCEROL, SULFATE ION 著者 Guarne, A, Almawi, A.W. 登録日 2018-07-28 公開日 2019-05-01 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Binding of the regulatory domain of MutL to the sliding beta-clamp is species specific. Nucleic Acids Res., 47, 2019
4N9A	E. coli sliding clamp in complex with (R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid 分子名称: (1R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid, CALCIUM ION, CHLORIDE ION, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-10-19 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
4N97	E. coli sliding clamp in complex with 5-nitroindole 分子名称: 5-nitro-1H-indole, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-10-19 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
4N99	E. coli sliding clamp in complex with 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-7-carboxylic acid 分子名称: 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-7-carboxylic acid, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Yin, Z, Oakley, A.J. 登録日 2013-10-19 公開日 2013-11-06 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach. J.Med.Chem., 57, 2014
6FVL	DNA polymerase sliding clamp from Escherichia coli with bound P7 peptide 分子名称: Beta sliding clamp, GLYCEROL, P7 peptide, ... 著者 Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D. 登録日 2018-03-04 公開日 2019-04-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.975 Å) 主引用文献 Peptide Interactions on Bacterial Sliding Clamps. Acs Infect Dis., 2019
6FVN	DNA polymerase sliding clamp from Mycobacterium tuberculosis with bound P7 peptide 分子名称: Beta sliding clamp, P7 peptide 著者 Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D. 登録日 2018-03-04 公開日 2019-04-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.142 Å) 主引用文献 Peptide Interactions on Bacterial Sliding Clamps. Acs Infect Dis., 2019
6FVO	Mutant DNA polymerase sliding clamp from Mycobacterium tuberculosis with bound P7 peptide 分子名称: Beta sliding clamp, CALCIUM ION, P7 peptide 著者 Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D. 登録日 2018-03-04 公開日 2019-04-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.689 Å) 主引用文献 Peptide Interactions on Bacterial Sliding Clamps. Acs Infect Dis., 2019
6FVM	Mutant DNA polymerase sliding clamp from Escherichia coli with bound P7 peptide 分子名称: Beta sliding clamp, CALCIUM ION, GLYCEROL, ... 著者 Martiel, I, Andre, C, Olieric, V, Guichard, G, Burnouf, D. 登録日 2018-03-04 公開日 2019-04-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.631 Å) 主引用文献 Peptide Interactions on Bacterial Sliding Clamps. Acs Infect Dis., 2019
6AMS	Crystal structure of the DNA polymerase III subunit beta from Pseudomonas aeruginosa 分子名称: Beta sliding clamp, PHOSPHATE ION 著者 McGrath, A.E, Oakley, A.J. 登録日 2017-08-11 公開日 2017-11-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.39 Å) 主引用文献 Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens. J. Struct. Biol., 204, 2018
6AP4	Crystal structure of the DNA polymerase III subunit beta from Acinetobacter baumannii 分子名称: DNA polymerase III subunit beta, MAGNESIUM ION 著者 McGrath, A.E, Oakley, A.J. 登録日 2017-08-16 公開日 2017-12-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Crystal structures and biochemical characterization of DNA sliding clamps from three Gram-negative bacterial pathogens. J. Struct. Biol., 204, 2018
3Q4K	Structure of a small peptide ligand bound to E.coli DNA sliding clamp 分子名称: DNA polymerase III subunit beta, peptide ligand 著者 Wolff, P, Olieric, V, Briand, J.P, Chaloin, O, Dejaegere, A, Dumas, P, Ennifar, E, Guichard, G, Wagner, J, Burnouf, D. 登録日 2010-12-23 公開日 2011-12-28 最終更新日 2013-03-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-based design of short peptide ligands binding onto the E. coli processivity ring. J.Med.Chem., 54, 2011
3Q4L	Structure of a small peptide ligand bound to E.coli DNA sliding clamp 分子名称: DNA polymerase III subunit beta, SODIUM ION, peptide ligand 著者 Wolff, P, Olieric, V, Briand, J.P, Chaloin, O, Dejaegere, A, Dumas, P, Ennifar, E, Guichard, G, Wagner, J, Burnouf, D. 登録日 2010-12-23 公開日 2011-12-28 最終更新日 2013-03-20 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-based design of short peptide ligands binding onto the E. coli processivity ring. J.Med.Chem., 54, 2011

<12345>