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6OXD
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BU of 6oxd by Molmil
Structure of Mycobacterium tuberculosis methylmalonyl-CoA mutase with adenosyl cobalamin
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, Itaconyl coenzyme A, ...
著者Purchal, M, Ruetz, M, Banerjee, R, Koutmos, M.
登録日2019-05-13
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair.
Science, 366, 2019
3BIC
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BU of 3bic by Molmil
Crystal structure of human methylmalonyl-CoA mutase
分子名称: CHLORIDE ION, Methylmalonyl-CoA mutase, mitochondrial precursor
著者Ugochukwu, E, Kochan, G, Pantic, N, Parizotto, E, Pilka, E.S, Pike, A.C.W, Gileadi, O, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A.M, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2007-11-30
公開日2007-12-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of the human GTPase MMAA and vitamin B12-dependent methylmalonyl-CoA mutase and insight into their complex formation.
J.Biol.Chem., 285, 2010
1REQ
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BU of 1req by Molmil
METHYLMALONYL-COA MUTASE
分子名称: COBALAMIN, DESULFO-COENZYME A, GLYCEROL, ...
著者Evans, P.R, Mancia, F.
登録日1996-01-19
公開日1997-01-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 A resolution.
Structure, 4, 1996
2XIJ
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BU of 2xij by Molmil
Crystal structure of human methylmalonyl-CoA mutase in complex with adenosylcobalamin
分子名称: 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-DEOXYADENOSINE, ...
著者Yue, W.W, Froese, D.S, Kochan, G, Chaikuad, A, Krojer, T, Muniz, J, Vollmar, M, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U.
登録日2010-06-30
公開日2010-09-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the Human Gtpase Mmaa and Vitamin B12-Dependent Methylmalonyl-Coa Mutase and Insight Into Their Complex Formation.
J.Biol.Chem., 285, 2010
4XC7
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BU of 4xc7 by Molmil
Isobutyryl-CoA mutase fused with bound butyryl-CoA and without cobalamin or GDP (apo-IcmF)
分子名称: Butyryl Coenzyme A, Isobutyryl-CoA mutase fused, L(+)-TARTARIC ACID
著者Jost, M, Drennan, C.L.
登録日2014-12-17
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Visualization of a radical B12 enzyme with its G-protein chaperone.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XC6
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BU of 4xc6 by Molmil
Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, and Mg (holo-IcmF/GDP)
分子名称: 5'-DEOXYADENOSINE, ACETATE ION, COBALAMIN, ...
著者Jost, M, Drennan, C.L.
登録日2014-12-17
公開日2015-02-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Visualization of a radical B12 enzyme with its G-protein chaperone.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XC8
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BU of 4xc8 by Molmil
Isobutyryl-CoA mutase fused with bound butyryl-CoA, GDP, and Mg and without cobalamin (apo-IcmF/GDP)
分子名称: Butyryl Coenzyme A, GUANOSINE-5'-DIPHOSPHATE, Isobutyryl-CoA mutase fused, ...
著者Jost, M, Drennan, C.L.
登録日2014-12-17
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Visualization of a radical B12 enzyme with its G-protein chaperone.
Proc.Natl.Acad.Sci.USA, 112, 2015
2XIQ
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BU of 2xiq by Molmil
Crystal structure of human methylmalonyl-CoA mutase in complex with adenosylcobalamin and malonyl-CoA
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, MALONYL-COENZYME A, ...
著者Yue, W.W, Froese, D.S, Kochan, G, Chaikuad, A, Krojer, T, Muniz, J, Ugochukwu, E, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U.
登録日2010-06-30
公開日2010-09-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the Human Gtpase Mmaa and Vitamin B12-Dependent Methylmalonyl-Coa Mutase and Insight Into Their Complex Formation.
J.Biol.Chem., 285, 2010
5CJW
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BU of 5cjw by Molmil
Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, Mg (holo-IcmF/GDP), and substrate pivalyl-coenzyme A
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jost, M, Drennan, C.L.
登録日2015-07-15
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases.
J.Biol.Chem., 290, 2015
5CJV
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BU of 5cjv by Molmil
Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, Mg (holo-IcmF/GDP), and substrate isovaleryl-coenzyme A
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jost, M, Drennan, C.L.
登録日2015-07-15
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases.
J.Biol.Chem., 290, 2015
5CJT
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BU of 5cjt by Molmil
Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, Mg (holo-IcmF/GDP), and substrate isobutyryl-coenzyme A
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jost, M, Drennan, C.L.
登録日2015-07-15
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases.
J.Biol.Chem., 290, 2015
5CJU
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BU of 5cju by Molmil
Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, Mg (holo-IcmF/GDP), and substrate n-butyryl-coenzyme A
分子名称: 5'-DEOXYADENOSINE, Butyryl Coenzyme A, COBALAMIN, ...
著者Jost, M, Drennan, C.L.
登録日2015-07-15
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases.
J.Biol.Chem., 290, 2015
8DYJ
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BU of 8dyj by Molmil
Crystal structure of human methylmalonyl-CoA mutase in complex with ADP and cob(II)alamin
分子名称: ADENOSINE-5'-DIPHOSPHATE, COBALAMIN, Methylmalonyl-CoA mutase, ...
著者Mascarenhas, R.N, Gouda, H, Banerjee, R.
登録日2022-08-04
公開日2023-07-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Bivalent molecular mimicry by ADP protects metal redox state and promotes coenzyme B 12 repair.
Proc.Natl.Acad.Sci.USA, 120, 2023
8DYL
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BU of 8dyl by Molmil
Crystal structure of human methylmalonyl-CoA mutase bound to aquocobalamin
分子名称: COBALAMIN, GLYCEROL, Methylmalonyl-CoA mutase, ...
著者Mascarenhas, R.N, Gouda, H, Banerjee, R.
登録日2022-08-04
公開日2023-07-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Bivalent molecular mimicry by ADP protects metal redox state and promotes coenzyme B 12 repair.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G3H
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BU of 8g3h by Molmil
Structure of cobalamin-dependent methionine synthase (MetH) in a resting state
分子名称: COBALAMIN, Methionine synthase, ZINC ION
著者Watkins, M.B, Ando, N.
登録日2023-02-07
公開日2023-06-28
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Conformational switching and flexibility in cobalamin-dependent methionine synthase studied by small-angle X-ray scattering and cryoelectron microscopy.
Proc.Natl.Acad.Sci.USA, 120, 2023
8STA
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BU of 8sta by Molmil
Isobutyryl-CoA mutase fused in the presence of GMPPCP
分子名称: Isobutyryl-CoA mutase fused
著者Vaccaro, F.A, Drennan, C.L.
登録日2023-05-09
公開日2023-08-09
最終更新日2023-09-13
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Structural insight into G-protein chaperone-mediated maturation of a bacterial adenosylcobalamin-dependent mutase.
J.Biol.Chem., 299, 2023
8SSC
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BU of 8ssc by Molmil
Full-Length Methionine synthase from Thermus thermophilus HB8
分子名称: Methionine synthase, POTASSIUM ION, SULFATE ION
著者Yamada, K, Mendoza, J, Koutmos, M.
登録日2023-05-08
公開日2023-10-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure of full-length cobalamin-dependent methionine synthase and cofactor loading captured in crystallo.
Nat Commun, 14, 2023
8SSL
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BU of 8ssl by Molmil
Isobutyryl-CoA mutase fused Q341A in the presence of GTP
分子名称: Fused isobutyryl-CoA mutase, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Vaccaro, F.A, Drennan, C.L.
登録日2023-05-08
公開日2024-05-08
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural insight into G-protein chaperone-mediated maturation of a bacterial adenosylcobalamin-dependent mutase.
J.Biol.Chem., 299, 2023
1OZ9
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BU of 1oz9 by Molmil
Crystal structure of AQ_1354, a hypothetical protein from Aquifex aeolicus
分子名称: Hypothetical protein AQ_1354
著者Oganesyan, V, Busso, D, Brandsen, J, Chen, S, Jancarik, J, Kim, R, Kim, S.H, Berkeley Structural Genomics Center (BSGC)
登録日2003-04-08
公開日2003-09-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.894 Å)
主引用文献Structure of the hypothetical protein AQ_1354 from Aquifex aeolicus.
Acta Crystallogr.,Sect.D, 59, 2003
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