PDB: 493 件ウェブページステータス検索Chemie searchBIRD

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4DVX	Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with MAE-II-188 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-(4-chloro-3-fluorophenyl)-N'-{[(3R)-1-cyclopropylpyrrolidin-3-yl]methyl}ethanediamide, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2012-02-23 公開日 2013-02-27 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site. Plos One, 9, 2014
4DVS	Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with NBD-557 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-(4-bromophenyl)-N'-(2,2,6,6-tetramethylpiperidin-4-yl)ethanediamide, ... 著者 Kwon, Y.D, Kwong, P.D. 登録日 2012-02-23 公開日 2013-02-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structures of HIV-1 gp120 Envelope Glycoprotein in Complex with NBD Analogues That Target the CD4-Binding Site. Plos One, 9, 2014
4DKU	Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with NBD-09027 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 gp120 core, ... 著者 Kwon, Y.D, Debnath, A.K, Kwong, P.D. 登録日 2012-02-04 公開日 2013-03-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4902 Å) 主引用文献 Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study. Antimicrob. Agents Chemother., 58, 2014
4DKV	Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with NBD-10007 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 gp120 core, ... 著者 Kwon, Y.D, Debnath, A.K, Kwong, P.D. 登録日 2012-02-04 公開日 2013-03-20 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1847 Å) 主引用文献 Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study. Antimicrob. Agents Chemother., 58, 2014
4JDT	Crystal structure of chimeric germ-line precursor of NIH45-46 Fab in complex with gp120 of 93TH057 HIV-1 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... 著者 Scharf, L, Diskin, R, Bjorkman, P.J. 登録日 2013-02-25 公開日 2013-03-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.26 Å) 主引用文献 Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody. Proc.Natl.Acad.Sci.USA, 110, 2013
4JAN	crystal structure of broadly neutralizing antibody CH103 in complex with HIV-1 gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103, ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103, ... 著者 Zhou, T, Moquin, S, Zheng, A, Srivatsan, S, Kwong, P.D. 登録日 2013-02-18 公開日 2013-04-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature, 496, 2013
4JPJ	Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6 著者 Julien, J.-P, Jardine, J, Schief, W.R, Wilson, I.A. 登録日 2013-03-19 公開日 2013-04-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Rational HIV immunogen design to target specific germline B cell receptors. Science, 340, 2013
4JPK	Crystal structure of the germline-targeting HIV-1 gp120 engineered outer domain eOD-GT6 in complex with a putative VRC01 germline precursor Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Germline-targeting HIV-1 gp120 engineered outer domain, eOD-GT6, ... 著者 Julien, J.-P, Jardine, J, Schief, W.R, Wilson, I.A. 登録日 2013-03-19 公開日 2013-04-10 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Rational HIV immunogen design to target specific germline B cell receptors. Science, 340, 2013
4JPW	Crystal structure of broadly and potently neutralizing antibody 12a21 in complex with hiv-1 strain 93th057 gp120 mutant 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEAVY CHAIN OF ANTIBODY 12A21, ... 著者 Acharya, P, Luongo, T, Zhou, T, Kwong, P.D. 登録日 2013-03-19 公開日 2013-04-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.904 Å) 主引用文献 Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization. Cell(Cambridge,Mass.), 153, 2013
4JPV	Crystal structure of broadly and potently neutralizing antibody 3bnc117 in complex with hiv-1 gp120 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Zhou, T, Moquin, S, Kwong, P.D. 登録日 2013-03-19 公開日 2013-04-17 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.827 Å) 主引用文献 Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization. Cell(Cambridge,Mass.), 153, 2013
4JB9	Crystal structure of antibody VRC06 in complex with HIV-1 gp120 core 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, antibody VRC06 heavy chain, antibody VRC06 light chain, ... 著者 Kwon, Y.D, Zhou, T, Srivatsan, S, Kwong, P.D. 登録日 2013-02-19 公開日 2013-05-08 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization. Science, 340, 2013
4J6R	Crystal structure of broadly and potently neutralizing antibody VRC23 in complex with HIV-1 gp120 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, (R,R)-2,3-BUTANEDIOL, 1,2-ETHANEDIOL, ... 著者 Zhou, T, Moquin, S, Kwong, P.D. 登録日 2013-02-11 公開日 2013-05-08 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Delineating antibody recognition in polyclonal sera from patterns of HIV-1 isolate neutralization. Science, 340, 2013
4JKP	Restricting HIV-1 Pathways for Escape using Rationally-Designed Anti-HIV-1 Antibodies 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of antibody 45-46M2, Light chain of antibody 45-46M2, ... 著者 Diskin, R, Bjorkman, P.J. 登録日 2013-03-11 公開日 2013-05-15 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.82 Å) 主引用文献 Restricting HIV-1 pathways for escape using rationally designed anti-HIV-1 antibodies. J.Exp.Med., 210, 2013
4I53	Crystal structure of clade C1086 HIV-1 gp120 core in complex with DMJ-II-121 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FORMIC ACID, HIV-1 glycoprotein, ... 著者 Le-Khac, M, Hendrickson, W.A. 登録日 2012-11-28 公開日 2013-05-29 最終更新日 2021-05-26 実験手法 X-RAY DIFFRACTION (2.5002 Å) 主引用文献 Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization. ACS Med Chem Lett, 4, 2013
4JM2	Crystal Structure of PGT 135 Fab in Complex with gp120 Core Protein from HIV-1 Strain JR-FL Bound to CD4 and 17b Fab 分子名称: 17b Heavy chain, 17b Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kong, L, Wilson, I.A. 登録日 2013-03-13 公開日 2013-05-29 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nat.Struct.Mol.Biol., 20, 2013
4I54	Crystal structure of clade A/E 93TH057 HIV-1 gp120 H375S core in complex with DMJ-II-121 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HIV-1 glycoprotein, ... 著者 Le-Khac, M, Hendrickson, W.A. 登録日 2012-11-28 公開日 2013-05-29 最終更新日 2021-05-26 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-Based Design and Synthesis of an HIV-1 Entry Inhibitor Exploiting X-Ray and Thermodynamic Characterization. ACS Med Chem Lett, 4, 2013
4K0A	Crystal structure of CD4-mimetic miniprotein M48U7 in complex with HIV-1 YU2 gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-MIMETIC MINIPROTEIN M48U7, CITRATE ANION, ... 著者 Acharya, P, Kwong, P.D. 登録日 2013-04-03 公開日 2013-06-12 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 A Cocrystal Structure of gp120 and M48U1. Structure, 21, 2013
4JZZ	Crystal structure of CD4-mimetic miniprotein M48U1 in complex with HIV-1 YU2 gp120 in C2221 space group 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-MIMETIC MINIPROTEIN M48U1, CITRATE ANION, ... 著者 Acharya, P, Kwong, P.D. 登録日 2013-04-03 公開日 2013-06-12 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 A Cocrystal Structure of gp120 and M48U1. Structure, 21, 2013
4JZW	Crystal structure of CD4-mimetic miniprotein M48U1 in complex with HIV-1 YU2 gp120 in P212121 space group 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CD4-MIMETIC MINIPROTEIN M48U1, ... 著者 Acharya, P, Kwong, P.D. 登録日 2013-04-03 公開日 2013-06-12 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.784 Å) 主引用文献 Structural Basis for Highly Effective HIV-1 Neutralization by CD4-Mimetic Miniproteins Revealed by 1.5 A Cocrystal Structure of gp120 and M48U1. Structure, 21, 2013
4KA2	Crystal structure of CD4-mimetic miniprotein M48U12 in complex with HIV-1 YU2 gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 YU2 gp120, M48U12 著者 Acharya, P, Kwong, P.D. 登録日 2013-04-21 公開日 2013-06-19 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Interfacial Cavity Filling To Optimize CD4-Mimetic Miniprotein Interactions with HIV-1 Surface Glycoprotein. J.Med.Chem., 56, 2013
4LAJ	Crystal structure of HIV-1 YU2 envelope gp120 glycoprotein in complex with CD4-mimetic miniprotein, M48U1, and llama single-domain, broadly neutralizing, co-receptor binding site antibody, JM4 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-AMINOHEXANOIC ACID, ... 著者 Acharya, P, Luongo, T.S, Kwong, P.D. 登録日 2013-06-20 公開日 2013-08-14 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites. J.Virol., 87, 2013
4LSS	Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 clade A strain KER_2018_11 gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEAVY CHAIN OF ANTIBODY VRC01, ... 著者 Zhou, T, Moquin, S, Kwong, P.D. 登録日 2013-07-23 公開日 2013-08-21 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies. Immunity, 39, 2013
4LSQ	Crystal structure of broadly and potently neutralizing antibody VRC-CH31 in complex with HIV-1 clade A/E gp120 93TH057 with LOOP D and Loop V5 from clade A strain 3415_v1_c1 分子名称: (R,R)-2,3-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CADMIUM ION, ... 著者 Zhou, T, Moquin, S, Kwong, P.D. 登録日 2013-07-23 公開日 2013-08-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies. Immunity, 39, 2013
4LST	Crystal structure of broadly and potently neutralizing antibody VRC01 in complex with HIV-1 clade C strain ZM176.66 gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ENVELOPE GLYCOPROTEIN GP120 of HIV-1 clade C, HEAVY CHAIN OF ANTIBODY VRC01, ... 著者 Zhou, T, Moquin, S, Kwong, P.D. 登録日 2013-07-23 公開日 2013-08-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies. Immunity, 39, 2013
4LSV	Crystal structure of broadly and potently neutralizing antibody 3BNC117 in complex with HIV-1 clade C C1086 gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEAVY CHAIN OF ANTIBODY 3BNC117, IMIDAZOLE, ... 著者 Zhou, T, Moquin, S, Kwong, P.D. 登録日 2013-07-23 公開日 2013-08-21 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Multidonor Analysis Reveals Structural Elements, Genetic Determinants, and Maturation Pathway for HIV-1 Neutralization by VRC01-Class Antibodies. Immunity, 39, 2013

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