6F5V
| Crystal structure of the prephenate aminotransferase from Arabidopsis thaliana | 分子名称: | Bifunctional aspartate aminotransferase and glutamate/aspartate-prephenate aminotransferase, CITRIC ACID, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Cobessi, D, Robin, A, Giustini, C, Graindorge, M, Matringe, M. | 登録日 | 2017-12-03 | 公開日 | 2019-03-13 | 最終更新日 | 2019-06-12 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Tyrosine metabolism: identification of a key residue in the acquisition of prephenate aminotransferase activity by 1 beta aspartate aminotransferase. Febs J., 286, 2019
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6F35
| Crystal structure of the aspartate aminotranferase from Rhizobium meliloti | 分子名称: | ACETATE ION, Aspartate aminotransferase B, GLYCEROL, ... | 著者 | Cobessi, D, Graindorge, M, Giustini, C, Matringe, M. | 登録日 | 2017-11-28 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Tyrosine metabolism: identification of a key residue in the acquisition of prephenate aminotransferase activity by 1 beta aspartate aminotransferase. Febs J., 286, 2019
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6S8W
| Aromatic aminotransferase AroH (Aro8) form Aspergillus fumigatus in complex with PLP (internal aldimine) | 分子名称: | Aromatic aminotransferase Aro8, putative, FORMIC ACID, ... | 著者 | Giardina, G, Mirco, D, Spizzichino, S, Zelante, T, Cutruzzola, F, Romani, L, Cellini, B. | 登録日 | 2019-07-10 | 公開日 | 2020-08-26 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of Aspergillus fumigatus AroH, an aromatic amino acid aminotransferase Proteins, 2021
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4WLH
| High resolution crystal structure of human kynurenine aminotransferase-I bound to PLP cofactor | 分子名称: | Kynurenine--oxoglutarate transaminase 1 | 著者 | Nadvi, N.A, Salam, N.K, Park, J, Akladios, F.N, Kapoor, V, Collyer, C.A, Gorrell, M.D, Church, W.B. | 登録日 | 2014-10-07 | 公開日 | 2014-12-03 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate. Protein Sci., 26, 2017
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6F77
| Crystal structure of the prephenate aminotransferase from Rhizobium meliloti | 分子名称: | Aspartate aminotransferase A, PYRIDOXAL-5'-PHOSPHATE | 著者 | Cobessi, D, Giustini, C, Graindorge, M, Matringe, M. | 登録日 | 2017-12-07 | 公開日 | 2019-03-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.794 Å) | 主引用文献 | Tyrosine metabolism: identification of a key residue in the acquisition of prephenate aminotransferase activity by 1 beta aspartate aminotransferase. Febs J., 286, 2019
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6T8P
| HKATII IN COMPLEX WITH LIGAND (2R)-N-benzyl-1-[6-methyl-5-(oxan-4-yl)-7-oxo-6H,7H-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2-carboxamide | 分子名称: | 1,2-ETHANEDIOL, 3,5-bis(fluoranyl)-~{N}-[5-[(2~{R})-2-(3-fluorophenyl)-3-methyl-butyl]-1,3,4-thiadiazol-2-yl]benzenesulfonamide, IODIDE ION, ... | 著者 | Blaesse, M, Venalainen, J. | 登録日 | 2019-10-24 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Discovery of sulfonamides and 9-oxo-2,8-diazaspiro[5,5]undecane-2-carboxamides as human kynurenine aminotransferase 2 (KAT2) inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
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6T3V
| Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with substrate analog - malic acid | 分子名称: | (2S)-2-hydroxybutanedioic acid, Aminotransferase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Rutkiewicz, M, Bujacz, A, Rum, J, Bujacz, G. | 登録日 | 2019-10-11 | 公開日 | 2020-11-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Structural Evidence of Active Site Adaptability towards Different Sized Substrates of Aromatic Amino Acid Aminotransferase from Psychrobacter Sp. B6. Materials, 14, 2021
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6T8Q
| HKATII IN COMPLEX WITH LIGAND (2R)-N-benzyl-1-[6-methyl-5-(oxan-4-yl)-7-oxo-6H,7H-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]pyrrolidine-2-carboxamide | 分子名称: | (2~{R})-1-[6-methyl-5-(oxan-4-yl)-7-oxidanylidene-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]-~{N}-(phenylmethyl)pyrrolidine-2-carboxamide, ACETATE ION, CADMIUM ION, ... | 著者 | Blaesse, M, Venalainen, J. | 登録日 | 2019-10-24 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Discovery of sulfonamides and 9-oxo-2,8-diazaspiro[5,5]undecane-2-carboxamides as human kynurenine aminotransferase 2 (KAT2) inhibitors. Bioorg.Med.Chem.Lett., 30, 2020
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7AAT
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4R2N
| Crystal structure of Rv3772 in complex with its substrate | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, PHENYLALANINE, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Nasir, N, Anant, A, Vyas, R, Biswal, B.K. | 登録日 | 2014-08-12 | 公開日 | 2015-08-12 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Crystal structures of Mycobacterium tuberculosis HspAT and ArAT reveal structural basis of their distinct substrate specificities Sci Rep, 6, 2016
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4RAE
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4R8D
| Crystal structure of Rv1600 encoded aminotransferase in complex with PLP-MES from Mycobacterium tuberculosis | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Histidinol-phosphate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Nasir, N, Anant, A, Vyas, R, Biswal, B.K. | 登録日 | 2014-09-01 | 公開日 | 2015-09-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of Rv1600 encoded aminotransferase in complex with PLP-MES from Mycobacterium tuberculosis To be Published
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4R5Z
| Crystal structure of Rv3772 encoded aminotransferase | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... | 著者 | Nasir, N, Anant, A, Vyas, R, Biswal, B.K. | 登録日 | 2014-08-22 | 公開日 | 2015-08-26 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal structures of Mycobacterium tuberculosis HspAT and ArAT reveal structural basis of their distinct substrate specificities Sci Rep, 6, 2016
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4RKD
| Psychrophilic aromatic amino acids aminotransferase from Psychrobacter sp. B6 cocrystalized with aspartic acid | 分子名称: | 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYLENE)-AMINO]-SUCCINIC ACID, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aromatic amino acid aminotransferase, ... | 著者 | Bujacz, A, Rutkiewicz-Krotewicz, M, Bujacz, G, Nowakowska-Sapota, K, Turkiewicz, M. | 登録日 | 2014-10-12 | 公開日 | 2015-03-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Crystal structure and enzymatic properties of a broad substrate-specificity psychrophilic aminotransferase from the Antarctic soil bacterium Psychrobacter sp. B6. Acta Crystallogr.,Sect.D, 71, 2015
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5BJ4
| THERMUS THERMOPHILUS ASPARTATE AMINOTRANSFERASE TETRA MUTANT 2 | 分子名称: | PHOSPHATE ION, PROTEIN (ASPARTATE AMINOTRANSFERASE), PYRIDOXAL-5'-PHOSPHATE | 著者 | Ura, H, Nakai, T, Kawaguchi, S.I, Miyahara, I, Hirotsu, K, Kuramitsu, S. | 登録日 | 1999-01-11 | 公開日 | 2003-09-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Substrate recognition mechanism of thermophilic dual-substrate enzyme J.BIOCHEM.(TOKYO), 130, 2001
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7POC
| An Irreversible, Promiscuous and Highly Thermostable Claisen-Condensation Biocatalyst Drives the Synthesis of Substituted Pyrroles | 分子名称: | 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase, PYRIDOXAL-5'-PHOSPHATE | 著者 | Basle, A, Ashley, B, Campopiano, D, Marles-Wright, J. | 登録日 | 2021-09-08 | 公開日 | 2022-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Versatile Chemo-Biocatalytic Cascade Driven by a Thermophilic and Irreversible C-C Bond-Forming alpha-Oxoamine Synthase. Acs Sustain Chem Eng, 11, 2023
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7POA
| An Irreversible, Promiscuous and Highly Thermostable Claisen-Condensation Biocatalyst Drives the Synthesis of Substituted Pyrroles | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Basle, A, Ashley, B, Campopiano, D, Marles-Wright, J. | 登録日 | 2021-09-08 | 公開日 | 2022-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Versatile Chemo-Biocatalytic Cascade Driven by a Thermophilic and Irreversible C-C Bond-Forming alpha-Oxoamine Synthase. Acs Sustain Chem Eng, 11, 2023
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7POB
| An Irreversible, Promiscuous and Highly Thermostable Claisen-Condensation Biocatalyst Drives the Synthesis of Substituted Pyrroles | 分子名称: | 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION | 著者 | Basle, A, Ashley, B, Campopiano, D, Marles-Wright, J. | 登録日 | 2021-09-08 | 公開日 | 2022-09-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Versatile Chemo-Biocatalytic Cascade Driven by a Thermophilic and Irreversible C-C Bond-Forming alpha-Oxoamine Synthase. Acs Sustain Chem Eng, 11, 2023
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1OXP
| ASPARTATE AMINOTRANSFERASE, H-ASP COMPLEX, CLOSED CONFORMATION | 分子名称: | 4'-DEOXY-4'-ACETYLYAMINO-PYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE | 著者 | Hohenester, E, Schirmer, T, Jansonius, J.N. | 登録日 | 1995-12-23 | 公開日 | 1996-06-10 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structures and solution studies of oxime adducts of mitochondrial aspartate aminotransferase. Eur.J.Biochem., 236, 1996
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8I7U
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1O4S
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8IYT
| Crystal Structure of Serine Palmitoyltransferase complexed with D-methylserine | 分子名称: | (2~{R})-2-methyl-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-3-oxidanyl-propanoic acid, 1,2-ETHANEDIOL, Serine palmitoyltransferase | 著者 | Takahashi, A, Murakami, T, Katayama, A, Miyahara, I, Kamiya, N, Ikushiro, H, Yano, T. | 登録日 | 2023-04-06 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of Serine Palmitoyltransferase from Sphingobacterium multivorum To Be Published
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8IYP
| Crystal structure of serine palmitoyltransferase soaked in 190 mM D-serine solution | 分子名称: | 1,2-ETHANEDIOL, Serine palmitoyltransferase, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE | 著者 | Takahashi, A, Murakami, T, Katayama, A, Miyahara, I, Kamiya, N, Ikushiro, H, Yano, T. | 登録日 | 2023-04-05 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | 主引用文献 | Crystal structure of Serine Palmitoyltransferase from Sphingobacterium multivorum To Be Published
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7RGB
| O2-, PLP-dependent desaturase Plu4 product-bound enzyme | 分子名称: | (2Z,4E)-5-carbamimidamido-2-iminopent-4-enoic acid, 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | 著者 | Hoffarth, E.R, Ryan, K.S. | 登録日 | 2021-07-14 | 公開日 | 2021-10-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A shared mechanistic pathway for pyridoxal phosphate-dependent arginine oxidases. Proc.Natl.Acad.Sci.USA, 118, 2021
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5DJ3
| Structure of the PLP-Dependent L-Arginine Hydroxylase MppP with D-Arginine Bound | 分子名称: | (E)-N~2~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-D-arginine, MAGNESIUM ION, PLP-Dependent L-Arginine Hydroxylase MppP | 著者 | Silvaggi, N.R, Han, L. | 登録日 | 2015-09-01 | 公開日 | 2015-11-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.227 Å) | 主引用文献 | Streptomyces wadayamensis MppP Is a Pyridoxal 5'-Phosphate-Dependent l-Arginine alpha-Deaminase, gamma-Hydroxylase in the Enduracididine Biosynthetic Pathway. Biochemistry, 54, 2015
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