PDB: 1500 件ウェブページステータス検索Chemie searchBIRD

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3JB9	Cryo-EM structure of the yeast spliceosome at 3.6 angstrom resolution 分子名称: ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Yan, C, Hang, J, Wan, R, Huang, M, Wong, C, Shi, Y. 登録日 2015-08-09 公開日 2015-09-23 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of a yeast spliceosome at 3.6-angstrom resolution Science, 349, 2015
5WSG	Cryo-EM structure of the Catalytic Step II spliceosome (C* complex) at 4.0 angstrom resolution 分子名称: 3'-exon-intron, 3'-intron-lariat, 5'-exon, ... 著者 Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y. 登録日 2016-12-07 公開日 2017-01-25 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structure of a yeast step II catalytically activated spliceosome Science, 355, 2017
5YLZ	Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6 angstrom 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. 登録日 2017-10-20 公開日 2018-07-18 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae Cell, 171, 2017
5MQ0	Structure of a spliceosome remodeled for exon ligation 分子名称: 3'-EXON OF UBC4 PRE-MRNA, BOUND BY PRP22 HELICASE, 5'-EXON OF UBC4 PRE-MRNA, ... 著者 Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. 登録日 2016-12-19 公開日 2017-01-18 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (4.17 Å) 主引用文献 Structure of a spliceosome remodelled for exon ligation. Nature, 542, 2017
6AH0	The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... 著者 Zhan, X, Yan, C, Zhang, X, Shi, Y. 登録日 2018-08-15 公開日 2018-11-14 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (5.7 Å) 主引用文献 Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell Res., 28, 2018
5MPS	Structure of a spliceosome remodeled for exon ligation 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, MAGNESIUM ION, ... 著者 Fica, S.M, Oubridge, C, Galej, W.P, Wilkinson, M.E, Newman, A.J, Bai, X.-C, Nagai, K. 登録日 2016-12-18 公開日 2017-01-18 最終更新日 2020-10-07 実験手法 ELECTRON MICROSCOPY (3.85 Å) 主引用文献 Structure of a spliceosome remodelled for exon ligation. Nature, 542, 2017
5Y88	Cryo-EM structure of the intron-lariat spliceosome ready for disassembly from S.cerevisiae at 3.5 angstrom 分子名称: GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, Intron lariat, ... 著者 Wan, R, Yan, C, Bai, R, Lei, J, Shi, Y. 登録日 2017-08-20 公開日 2018-08-01 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Structure of an Intron Lariat Spliceosome from Saccharomyces cerevisiae Cell(Cambridge,Mass.), 171, 2017
5LJ3	Structure of the core of the yeast spliceosome immediately after branching 分子名称: CEF1, CLF1, CWC15, ... 著者 Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K. 登録日 2016-07-17 公開日 2016-08-03 最終更新日 2019-10-23 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structure of the spliceosome immediately after branching. Nature, 537, 2016
5ZWM	Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom (tri-snRNP and U2 snRNP Part) 分子名称: 13 kDa ribonucleoprotein-associated protein, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, ... 著者 Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y. 登録日 2018-05-16 公開日 2018-08-29 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
5LJ5	Overall structure of the yeast spliceosome immediately after branching. 分子名称: CWC15, CWC22, Exon 1 (5' exon) of UBC4 pre-mRNA, ... 著者 Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K. 登録日 2016-07-17 公開日 2016-08-31 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structure of the spliceosome immediately after branching. Nature, 537, 2016
5ZWO	Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom 分子名称: 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... 著者 Bai, R, Wan, R, Yan, C, Shi, Y. 登録日 2018-05-16 公開日 2018-08-29 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
4CDO	Crystal structure of PQBP1 bound to spliceosomal U5-15kD 分子名称: THIOREDOXIN-LIKE PROTEIN 4A, POLYGLUTAMINE-BINDING PROTEIN 著者 Mizuguchi, M, Obita, T, Serita, T, Kojima, R, Nabeshima, Y, Okazawa, H. 登録日 2013-11-05 公開日 2014-04-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Mutations in the Pqbp1 Gene Prevent its Interaction with the Spliceosomal Protein U5-15Kd. Nat.Commun., 5, 2014
5LQW	yeast activated spliceosome 分子名称: Pre-mRNA leakage protein 1, Pre-mRNA-processing protein 45, Pre-mRNA-splicing factor 8, ... 著者 Rauhut, R, Luehrmann, R. 登録日 2016-08-17 公開日 2016-10-05 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Molecular architecture of the Saccharomyces cerevisiae activated spliceosome Science, 6306, 2016
5GMK	Cryo-EM structure of the Catalytic Step I spliceosome (C complex) at 3.4 angstrom resolution 分子名称: 5'-Exon, 5'-Splicing Site, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Wan, R, Yan, C, Bai, R, Huang, G, Shi, Y. 登録日 2016-07-14 公開日 2016-08-17 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Structure of a yeast catalytic step I spliceosome at 3.4 angstrom resolution Science, 353, 2016
1E7K	Crystal structure of the spliceosomal 15.5kD protein bound to a U4 snRNA fragment 分子名称: 15.5 KD RNA BINDING PROTEIN, RNA (5'-R(*GP*CP*CP*AP*AP*UP*GP*AP*GP*GP*UP*UP*UP* AP*UP*CP*CP*GP*AP*GP*G*C(-3') 著者 Vidovic, I, Nottrott, S, Harthmuth, K, Luhrmann, R, Ficner, R. 登録日 2000-08-29 公開日 2001-02-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal Structure of the Spliceosomal 15.5Kd Protein Bound to a U4 Snrna Fragment Mol.Cell, 6, 2000
5GM6	Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cold sensitive U2 snRNA suppressor 1, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y. 登録日 2016-07-12 公開日 2016-09-21 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of a yeast activated spliceosome at 3.5 angstrom resolution Science, 353, 2016
5GAN	The overall structure of the yeast spliceosomal U4/U6.U5 tri-snRNP at 3.7 Angstrom 分子名称: 13 kDa ribonucleoprotein-associated protein, GUANOSINE-5'-TRIPHOSPHATE, Pre-mRNA-processing factor 31, ... 著者 Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K. 登録日 2015-12-15 公開日 2016-01-27 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution. Nature, 530, 2016
7B9V	Yeast C complex spliceosome at 2.8 Angstrom resolution with Prp18/Slu7 bound 分子名称: 5' exon of UBC4 mRNA, BJ4_G0027490.mRNA.1.CDS.1, BJ4_G0054360.mRNA.1.CDS.1, ... 著者 Wilkinson, M.E, Fica, S.M, Galej, W.P, Nagai, K. 登録日 2020-12-14 公開日 2021-03-10 最終更新日 2021-04-14 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Structural basis for conformational equilibrium of the catalytic spliceosome. Mol.Cell, 81, 2021
5ZYA	SF3b spliceosomal complex bound to E7107 分子名称: PHD finger-like domain-containing protein 5A, POTASSIUM ION, Splicing factor 3B subunit 1, ... 著者 Finci, L.I, Larsen, N.A. 登録日 2018-05-23 公開日 2018-06-20 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.95 Å) 主引用文献 The cryo-EM structure of the SF3b spliceosome complex bound to a splicing modulator reveals a pre-mRNA substrate competitive mechanism of action Genes Dev., 32, 2018
4NHO	Structure of the spliceosomal DEAD-box protein Prp28 分子名称: 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GLYCEROL, MERCURY (II) ION, ... 著者 Moehlmann, S, Neumann, P, Ficner, R. 登録日 2013-11-05 公開日 2014-06-18 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural and functional analysis of the human spliceosomal DEAD-box helicase Prp28. Acta Crystallogr.,Sect.D, 70, 2014
6MX6	The Prp8 intein of Cryptococcus neoformans 分子名称: Pre-mRNA-processing-splicing factor 8 著者 Li, Z, Li, H. 登録日 2018-10-30 公開日 2019-10-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.749 Å) 主引用文献 Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing. Plos Biol., 17, 2019
6OWU	THE PRP8 INTEIN OF CRYPTOCOCCUS NEOFORMANS in complex with Zn2+ 分子名称: PRP8 protein, ZINC ION 著者 Li, Z, Li, H. 登録日 2019-05-11 公開日 2019-10-23 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing. Plos Biol., 17, 2019
2VRD	THE STRUCTURE OF THE ZINC FINGER FROM THE HUMAN SPLICEOSOMAL PROTEIN U1C 分子名称: U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C, ZINC ION 著者 Muto, Y, Pomeranz-Krummel, D, Oubridge, C, Hernandez, H, Robinson, C, Neuhaus, D, Nagai, K. 登録日 2008-03-31 公開日 2008-04-08 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The Structure and Biochemical Properties of the Human Spliceosomal Protein U1C J.Mol.Biol., 341, 2004
1LPW	Solution structure of the yeast spliceosomal U2 snRNA-intron branch site helix featuring a conserved pseudouridine 分子名称: 5'-R(*GP*GP*UP*GP*(PSU)P*AP*GP*UP*A)-3', 5'-R(*UP*AP*CP*UP*AP*AP*CP*AP*CP*C)-3' 著者 Newby, M.I, Greenbaum, N.L. 登録日 2002-05-08 公開日 2002-11-27 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Sculpting of the Spliceosomal Branch Site Recognition Motif by a Conserved Pseudouridine Nat.Struct.Biol., 12, 2002
5O9Z	Cryo-EM structure of a pre-catalytic human spliceosome primed for activation (B complex) 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, Homo sapiens RNA, U6 small nuclear 1 (RNU6-1), ... 著者 Bertram, K, Kastner, B. 登録日 2017-06-20 公開日 2017-08-16 最終更新日 2018-10-24 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation. Cell, 170, 2017

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