PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

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6DTZ	Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain, Y397F mutant 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, ... 著者 Salay, L.E, Chazin, W.J. 登録日 2018-06-18 公開日 2018-12-12 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Yeast require redox switching in DNA primase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6DU0	Crystal structure of eukaryotic DNA primase large subunit iron-sulfur cluster domain Y395L mutant 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, DNA primase large subunit, GLYCEROL, ... 著者 Salay, L.E, Chazin, W.J. 登録日 2018-06-18 公開日 2018-12-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Yeast require redox switching in DNA primase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1KDH	Binary Complex of Murine Terminal Deoxynucleotidyl Transferase with a Primer Single Stranded DNA 分子名称: 5'-D(P*(BRU)P*(BRU)P*(BRU)P*(BRU))-3', MAGNESIUM ION, SODIUM ION, ... 著者 Delarue, M, Boule, J.B, Lescar, J, Expert-Bezancon, N, Jourdan, N, Sukumar, N, Rougeon, F, Papanicolaou, C. 登録日 2001-11-13 公開日 2002-05-13 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structures of a template-independent DNA polymerase: murine terminal deoxynucleotidyltransferase. EMBO J., 21, 2002
3W34	Ternary complex of Thermus thermophilus HB8 uridine-cytidine kinase with substrates 分子名称: 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Uridine kinase 著者 Tomoike, F, Nakagawa, N, Masui, R, Kuramitsu, S. 登録日 2012-12-10 公開日 2013-12-11 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Structural and Biochemical Studies on the Reaction Mechanism of Uridine-Cytidine Kinase Protein J., 34, 2015
5J0R	Binary complex crystal structure of DNA polymerase Beta with C:A mismatch at the primer terminus 分子名称: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2016-03-28 公開日 2016-10-26 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J0X	Binary complex crystal structure of DNA polymerase Beta with T:G mismatch at the primer terminus 分子名称: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2016-03-28 公開日 2016-10-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J0O	Binary complex crystal structure of DNA polymerase Beta with A:A mismatch at the primer terminus 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*AP*AP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Batra, V.K, Wilson, S.H. 登録日 2016-03-28 公開日 2016-10-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J0W	Binary complex crystal structure of DNA polymerase Beta with T:C mismatch at the primer terminus 分子名称: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2016-03-28 公開日 2016-10-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
6S7D	Self-complementary duplex DNA containing an internucleoside phosphoroselenolate 分子名称: BARIUM ION, CHLORIDE ION, DNA (5'-D(*GP*(XCI)P*CP*CP*CP*GP*GP*GP*AP*C)-3'), ... 著者 Conlon, P.F, Steinhogl, J, Vyle, J.S, Hall, J.P. 登録日 2019-07-04 公開日 2019-11-06 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Solid-phase synthesis and structural characterisation of phosphoroselenolate-modified DNA: a backbone analogue which does not impose conformational bias and facilitates SAD X-ray crystallography. Chem Sci, 10, 2019
6LPB	Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short,Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Kobayashi, K, Shihoya, W, Nishizawa, T, Nureki, O. 登録日 2020-01-09 公開日 2020-03-11 最終更新日 2020-03-25 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein. Nat.Struct.Mol.Biol., 27, 2020
4PTF	Ternary crystal structure of yeast DNA polymerase epsilon with template G 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*AP*TP*CP*CP*TP*CP*CP*CP*CP*TP*AP*(DOC))-3', ... 著者 Jain, R, Rajashankar, K.R, Buku, A, Johnson, R.E, Prakash, L, Prakash, S, Aggarwal, A.K. 登録日 2014-03-10 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.809 Å) 主引用文献 Crystal Structure of Yeast DNA Polymerase epsilon Catalytic Domain. Plos One, 9, 2014
4XIU	Binary complex structure of Klenow fragment of Taq DNA polymerase I707L mutant with DNA containing TTT overhang 分子名称: DNA polymerase I, thermostable, MAGNESIUM ION, ... 著者 Wu, E.Y. 登録日 2015-01-07 公開日 2015-01-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A Conservative Isoleucine to Leucine Mutation Causes Major Rearrangements and Cold Sensitivity in KlenTaq1 DNA Polymerase. Biochemistry, 54, 2015
5Y7Y	Crystal structure of AhRR/ARNT complex 分子名称: Aryl hydrocarbon receptor nuclear translocator, Aryl hydrocarbon receptor repressor, GLYCEROL 著者 Sakurai, S, Shimizu, T, Ohto, U. 登録日 2017-08-18 公開日 2017-09-20 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The crystal structure of the AhRR-ARNT heterodimer reveals the structural basis of the repression of AhR-mediated transcription. J. Biol. Chem., 292, 2017
2RVH	NMR structure of eIF1 分子名称: Eukaryotic translation initiation factor eIF-1 著者 Nagata, T, Obayashi, E, Asano, K. 登録日 2015-10-16 公開日 2016-10-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5 Cell Rep, 18, 2017
6BEM	Ternary complex crystal structure of DNA polymerase Beta with S-isomer of beta-gamma-CHCL-dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 5'-O-[(R)-{[(R)-[(S)-chloro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]-2'-deoxycytidine, CHLORIDE ION, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2017-10-25 公開日 2018-10-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
6BEL	Ternary complex crystal structure of DNA polymerase Beta with R-isomer of beta-gamma-CHF-dCTP 分子名称: 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, 2'-deoxy-5'-O-[(R)-{[(R)-[(R)-fluoro(phosphono)methyl](hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]cytidine, CHLORIDE ION, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2017-10-25 公開日 2018-10-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.898 Å) 主引用文献 Mapping Functional Substrate-Enzyme Interactions in the pol beta Active Site through Chemical Biology: Structural Responses to Acidity Modification of Incoming dNTPs. Biochemistry, 57, 2018
3ARG	Ternary crystal structure of the mouse NKT TCR-CD1d-alpha-glucosylceramide(C20:2) 分子名称: (11E,14E)-N-[(2S,3S,4R)-1-(alpha-D-glucopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Wun, K.S, Rossjohn, J. 登録日 2010-11-27 公開日 2011-03-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells Immunity, 34, 2011
3ARB	Ternary crystal structure of the NKT TCR-CD1d-alpha-galactosylceramide analogue-OCH 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... 著者 Wun, K.S, Rossjohn, J. 登録日 2010-11-26 公開日 2011-03-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells Immunity, 34, 2011
3ARD	Ternary crystal structure of the mouse NKT TCR-CD1d-3'deoxy-alpha-galactosylceramide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, ... 著者 Wun, K.S, Rossjohn, J. 登録日 2010-11-27 公開日 2011-03-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells Immunity, 34, 2011
3ARE	Ternary crystal structure of the mouse NKT TCR-CD1d-4'deoxy-alpha-galactosylceramide 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... 著者 Wun, K.S, Rossjohn, J. 登録日 2010-11-27 公開日 2011-03-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells Immunity, 34, 2011
3ARF	Ternary crystal structure of the mouse NKT TCR-CD1d-C20:2 分子名称: (11Z,14E)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... 著者 Wun, K.S, Rossjohn, J. 登録日 2010-11-27 公開日 2011-03-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells Immunity, 34, 2011
6IPM	Binary Complex of Human DNA Polymerase Mu with MgdCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, ... 著者 Chang, Y.K, Wu, W.J, Tsai, M.D. 登録日 2018-11-03 公開日 2019-05-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
6IPL	Binary Complex of Human DNA Polymerase Mu with MgdATP 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MAGNESIUM ION, ... 著者 Chang, Y.K, Wu, W.J, Tsai, M.D. 登録日 2018-11-03 公開日 2019-05-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
6IPI	Binary Complex of Human DNA Polymerase Mu with MndCTP 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, ... 著者 Chang, Y.K, Wu, W.J, Tsai, M.D. 登録日 2018-11-03 公開日 2019-05-29 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141, 2019
4YD1	Ternary complex of human DNA Polymerase Mu with 2-nt gapped DNA substrate and an incoming nonhydrolyzable dUMPNPP 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, ... 著者 Moon, A.F, Gosavi, R.A, Kunkel, T.A, Pedersen, L.C, Bebenek, K. 登録日 2015-02-20 公開日 2015-08-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Creative template-dependent synthesis by human polymerase mu. Proc.Natl.Acad.Sci.USA, 112, 2015

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