PDB: 2906 件ウェブページステータス検索Chemie searchBIRD

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5HL7	The crystal structure of the large ribosomal subunit of Staphylococcus aureus in complex with lefamulin 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Eyal, Z, Matzov, D, Krupkin, M, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. 登録日 2016-01-14 公開日 2016-12-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.55 Å) 主引用文献 A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism. Sci Rep, 6, 2016
7PRT	Crystal structure of human heparanase in complex with covalent inhibitor CB678 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-alpha-D-arabino-hexopyranose-(1-4)-(2R,3S,5R,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexane-1-carboxylic acid, ... 著者 Wu, L, Armstrong, Z, Davies, G.J. 登録日 2021-09-22 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo. Proc.Natl.Acad.Sci.USA, 119, 2022
7PRB	Crystal structure of Burkholderia pseudomallei heparanase in complex with covalent inhibitor GR109 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-(2R,3S,5R,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexane-1-carboxylic acid, Glyco_hydro_44 domain-containing protein 著者 Wu, L, Armstrong, Z, Davies, G.J. 登録日 2021-09-21 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.31 Å) 主引用文献 Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo. Proc.Natl.Acad.Sci.USA, 119, 2022
7PSK	Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with covalent inhibitor GR109 分子名称: 2-acetamido-2-deoxy-6-O-sulfo-alpha-D-glucopyranose-(1-4)-(2R,3S,5R,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexane-1-carboxylic acid, Beta-glucuronidase 著者 Armstrong, Z, Wu, L, Davies, G.J. 登録日 2021-09-23 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.09 Å) 主引用文献 Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo. Proc.Natl.Acad.Sci.USA, 119, 2022
7PSJ	Crystal structure of beta-glucuronidase from Acidobacterium capsulatum in complex with covalent inhibitor VL166 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-(2R,3S,5R,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexane-1-carboxylic acid, Beta-glucuronidase 著者 Armstrong, Z, Wu, L, Davies, G.J. 登録日 2021-09-23 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo. Proc.Natl.Acad.Sci.USA, 119, 2022
7PR9	Crystal structure of Burkholderia pseudomallei heparanase in complex with covalent inhibitor VL166 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-(2R,3S,5R,6R)-2,3,4,5,6-pentakis(oxidanyl)cyclohexane-1-carboxylic acid, Glyco_hydro_44 domain-containing protein 著者 Wu, L, Armstrong, Z, Davies, G.J. 登録日 2021-09-21 公開日 2022-08-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.34 Å) 主引用文献 Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo. Proc.Natl.Acad.Sci.USA, 119, 2022
5J8A	Structure of the E coli 70S ribosome with the U1052G mutation in 16S rRNA bound to tigecycline 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... 著者 Cocozaki, A, Ferguson, A. 登録日 2016-04-07 公開日 2016-07-06 最終更新日 2016-08-03 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
5I4L	Crystal structure of Amicoumacin A bound to the yeast 80S ribosome 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Prokhorova, I.V, Yusupova, G, Yusupov, M. 登録日 2016-02-12 公開日 2016-06-22 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome. Sci Rep, 6, 2016
5JC9	Structure of the Escherichia coli ribosome with the U1052G mutation in the 16S rRNA 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... 著者 Cocozaki, A, Ferguson, A. 登録日 2016-04-14 公開日 2016-07-06 最終更新日 2016-08-03 実験手法 X-RAY DIFFRACTION (3.03 Å) 主引用文献 Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
5J7L	Structure of the 70S E coli ribosome with the U1052G mutation in the 16S rRNA bound to tetracycline 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... 著者 Cocozaki, A, Ferguson, A. 登録日 2016-04-06 公開日 2016-07-27 最終更新日 2018-08-15 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
5HCR	Crystal structure of antimicrobial peptide Oncocin 10wt bound to the Thermus thermophilus 70S ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. 登録日 2016-01-04 公開日 2016-04-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
7SBX	Structure of OC43 spike in complex with polyclonal Fab6 (Donor 1051) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... 著者 Bangaru, S, Antanasijevic, A, Ward, A. 登録日 2021-09-26 公開日 2022-05-04 最終更新日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural mapping of antibody landscapes to human betacoronavirus spike proteins. Sci Adv, 8, 2022
7SBY	Structure of OC43 spike in complex with polyclonal Fab7 (Donor 269) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... 著者 Bangaru, S, Antanasijevic, A, Ward, A. 登録日 2021-09-26 公開日 2022-05-04 最終更新日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural mapping of antibody landscapes to human betacoronavirus spike proteins. Sci Adv, 8, 2022
7SB3	Structure of OC43 spike in complex with polyclonal Fab1 (Donor 269) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... 著者 Ward, A, Bangaru, S, Antanasijevic, A. 登録日 2021-09-23 公開日 2022-05-04 最終更新日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural mapping of antibody landscapes to human betacoronavirus spike proteins. Sci Adv, 8, 2022
7SB4	Structure of OC43 spike in complex with polyclonal Fab2 (Donor 1412) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... 著者 Bangaru, S, Antanasijevic, A, Ward, A. 登録日 2021-09-23 公開日 2022-05-04 最終更新日 2022-05-18 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structural mapping of antibody landscapes to human betacoronavirus spike proteins. Sci Adv, 8, 2022
7SB5	Structure of OC43 spike in complex with polyclonal Fab3 (Donor 1412) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... 著者 Bangaru, S, Antanasijevic, A, Ward, A. 登録日 2021-09-23 公開日 2022-05-04 最終更新日 2022-05-18 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural mapping of antibody landscapes to human betacoronavirus spike proteins. Sci Adv, 8, 2022
7SBV	Structure of OC43 spike in complex with polyclonal Fab4 (Donor 269) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... 著者 Bangaru, S, Antanasijevic, A, Ward, A. 登録日 2021-09-26 公開日 2022-05-04 最終更新日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural mapping of antibody landscapes to human betacoronavirus spike proteins. Sci Adv, 8, 2022
7SBW	Structure of OC43 spike in complex with polyclonal Fab5 (Donor 1051) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Human polyclonal Fab model with polyalanine backbone - Heavy chain, ... 著者 Bangaru, S, Antanasijevic, A, Ward, A. 登録日 2021-09-26 公開日 2022-05-04 最終更新日 2022-05-18 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural mapping of antibody landscapes to human betacoronavirus spike proteins. Sci Adv, 8, 2022
5JVG	The large ribosomal subunit from Deinococcus radiodurans in complex with avilamycin 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 23S ribosomal RNA, 50S ribosomal protein L11, ... 著者 Krupkin, M, Wekselman, I, Matzov, D, Eyal, Z, Diskin Posner, Y, Rozenberg, H, Zimmerman, E, Bashan, A, Yonath, A. 登録日 2016-05-11 公開日 2016-11-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.428 Å) 主引用文献 Avilamycin and evernimicin induce structural changes in rProteins uL16 and CTC that enhance the inhibition of A-site tRNA binding. Proc.Natl.Acad.Sci.USA, 113, 2016
2RSK	RNA aptamer against prion protein in complex with the partial binding peptide 分子名称: RNA (5'-R(*GP*GP*AP*GP*GP*AP*GP*GP*AP*GP*GP*A)-3'), partial binding peptide of Major prion protein 著者 Mashima, T, Nishikawa, F, Kamatari, Y.O, Fujiwara, H, Nishikawa, S, Kuwata, K, Katahira, M. 登録日 2012-03-08 公開日 2013-02-13 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Anti-prion activity of an RNA aptamer and its structural basis Nucleic Acids Res., 41, 2013
5IB7	Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet, near-cognate tRNALys with U-G mismatch in the A-site and antibiotic paromomycin 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. 登録日 2016-02-22 公開日 2016-05-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix. Nucleic Acids Res., 44, 2016
2ON5	Structure of NaGST-2 分子名称: 1,2-ETHANEDIOL, GLUTATHIONE, Na Glutathione S-transferase 2 著者 Asojo, O.A, Ngamelue, M, Homma, H, Goud, G, Zhan, B, Hotez, P.J. 登録日 2007-01-23 公開日 2007-08-07 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray structures of Na-GST-1 and Na-GST-2 two glutathione s-transferase from the human hookworm Necator americanus Bmc Struct.Biol., 7, 2007
5HCQ	Crystal structure of antimicrobial peptide Oncocin d15-19 bound to the Thermus thermophilus 70S ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. 登録日 2016-01-04 公開日 2016-04-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.801 Å) 主引用文献 Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
2OM0	Structure of human insulin in presence of urea at pH 6.5 分子名称: CHLORIDE ION, Insulin A chain, Insulin B chain, ... 著者 Norrman, M, Schluckebier, G. 登録日 2007-01-20 公開日 2007-12-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH. Bmc Struct.Biol., 7, 2007
5J8B	Crystal structure of Elongation Factor 4 (EF-4/LepA) in complex with GDPCP bound to the Thermus thermophilus 70S ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... 著者 Gagnon, M.G, Lin, J, Steitz, T.A. 登録日 2016-04-07 公開日 2016-05-25 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Elongation factor 4 remodels the A-site tRNA on the ribosome. Proc.Natl.Acad.Sci.USA, 113, 2016

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