7ZKB
| ABCB1 V978C mutant (mABCB1) in the inward facing state | 分子名称: | (4S,11S,18S)-4-[[(2,4-dinitrophenyl)disulfanyl]methyl]-11,18-dimethyl-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, (4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, ATP-dependent translocase ABCB1 | 著者 | Parey, K, Januliene, D, Gewering, T, Moeller, A. | 登録日 | 2022-04-12 | 公開日 | 2023-04-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Tracing the substrate translocation mechanism in P-glycoprotein. Elife, 12, 2024
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7ZK8
| ABCB1 L971C mutant (mABCB1) in the outward facing state bound to AAC | 分子名称: | (4~{S},11~{S},18~{S})-4,11-dimethyl-18-(sulfanylmethyl)-6,13,20-trithia-3,10,17,22,23,24-hexazatetracyclo[17.2.1.1^{5,8}.1^{12,15}]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione, ADENOSINE-5'-TRIPHOSPHATE, ATP-dependent translocase ABCB1, ... | 著者 | Parey, K, Januliene, D, Gewering, T, Moeller, A. | 登録日 | 2022-04-12 | 公開日 | 2023-04-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Tracing the substrate translocation mechanism in P-glycoprotein. Elife, 12, 2024
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8CAH
| Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2023-01-24 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
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8CAS
| Cryo-EM structure of native Otu2-bound ubiquitinated 48S initiation complex (partial) | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | 著者 | Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2023-01-24 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
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7Y48
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8I4B
| Cryo-EM structure of apo-form ABCC4 | 分子名称: | ATP-binding cassette sub-family C member 4 | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | 登録日 | 2023-01-19 | 公開日 | 2023-05-24 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | 主引用文献 | Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
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8I4A
| Cryo-EM structure of dipyridamole-bound ABCC4 | 分子名称: | 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, ATP-binding cassette sub-family C member 4 | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | 登録日 | 2023-01-19 | 公開日 | 2023-05-24 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
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8I4C
| Cryo-EM structure of U46619-bound ABCC4 | 分子名称: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ATP-binding cassette sub-family C member 4 | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | 登録日 | 2023-01-19 | 公開日 | 2023-05-24 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
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8J3Z
| Cryo-EM structure of ATP-U46619-bound ABCC4 | 分子名称: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 4, ... | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | 登録日 | 2023-04-18 | 公開日 | 2023-05-24 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | 主引用文献 | Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
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8J3W
| Cryo-EM structure of aspirin-bound ABCC4 | 分子名称: | 2-(ACETYLOXY)BENZOIC ACID, ATP-binding cassette sub-family C member 4 | 著者 | Chen, Y, Wang, L, Hou, W.T, Zhou, C.Z, Chen, Y, Li, Q. | 登録日 | 2023-04-18 | 公開日 | 2023-05-24 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Cryo-EM structure ofABCC4 Nat Cardiovasc Res, 2023
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8HW4
| Cryo-EM structure of dehydroepiandrosterone sulfate-bound human ABC transporter ABCC3 in nanodiscs | 分子名称: | 17-oxoandrost-5-en-3beta-yl hydrogen sulfate, ATP-binding cassette sub-family C member 3 | 著者 | Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z. | 登録日 | 2022-12-28 | 公開日 | 2023-06-07 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | 主引用文献 | Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket. Embo J., 42, 2023
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8HW2
| Cryo-EM structure of beta-estradiol 17-(beta-D-glucuronide)-bound human ABC transporter ABCC3 in nanodiscs | 分子名称: | ATP-binding cassette sub-family C member 3, Estradiol-17beta-glucuronide | 著者 | Wang, J, Wang, F.F, Chen, Y.X, Zhou, C.Z. | 登録日 | 2022-12-28 | 公開日 | 2023-06-07 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.65 Å) | 主引用文献 | Placing steroid hormones within the human ABCC3 transporter reveals a compatible amphiphilic substrate-binding pocket. Embo J., 42, 2023
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8HVH
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8I6O
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8I6R
| Cryo-EM structure of Pseudomonas aeruginosa FtsE(E163Q)X/EnvC complex with ATP in peptidisc | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | 著者 | Xu, X, Li, J, Luo, M. | 登録日 | 2023-01-29 | 公開日 | 2023-06-07 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Mechanistic insights into the regulation of cell wall hydrolysis by FtsEX and EnvC at the bacterial division site. Proc.Natl.Acad.Sci.USA, 120, 2023
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8I6S
| Cryo-EM structure of Pseudomonas aeruginosa FtsE(E163Q)X/EnvC complex with ATP in peptidisc | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Cell division ATP-binding protein FtsE, Cell division protein FtsX, ... | 著者 | Xu, X, Li, J, Luo, M. | 登録日 | 2023-01-29 | 公開日 | 2023-06-07 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Mechanistic insights into the regulation of cell wall hydrolysis by FtsEX and EnvC at the bacterial division site. Proc.Natl.Acad.Sci.USA, 120, 2023
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8I6Q
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7Y1J
| Structure of SUR2A in complex with Mg-ATP and repaglinide in the inward-facing conformation. | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 9, MAGNESIUM ION, ... | 著者 | Chen, L, Ding, D, Hou, T. | 登録日 | 2022-06-08 | 公開日 | 2023-06-14 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix. Nat Commun, 14, 2023
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7Y1L
| Structure of SUR2B in complex with Mg-ATP and repaglinide in the inward-facing conformation | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Isoform SUR2B of ATP-binding cassette sub-family C member 9, MAGNESIUM ION, ... | 著者 | Chen, L, Ding, D, Hou, T. | 登録日 | 2022-06-08 | 公開日 | 2023-06-14 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.73 Å) | 主引用文献 | The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix. Nat Commun, 14, 2023
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7Y1K
| Structure of SUR2A in complex with Mg-ATP, Mg-ADP and repaglinide in the inward-facing conformation | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP-binding cassette sub-family C member 9, ... | 著者 | Chen, L, Ding, D, Hou, T. | 登録日 | 2022-06-08 | 公開日 | 2023-06-14 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix. Nat Commun, 14, 2023
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7Y1M
| Structure of SUR2B in complex with Mg-ATP, Mg-ADP, and repaglinide in the inward-facing conformation | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isoform SUR2B of ATP-binding cassette sub-family C member 9, ... | 著者 | Chen, L, Ding, D, Hou, T. | 登録日 | 2022-06-08 | 公開日 | 2023-06-14 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.57 Å) | 主引用文献 | The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix. Nat Commun, 14, 2023
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7Y1N
| Structure of SUR2B in complex with Mg-ATP, Mg-ADP, and repaglinide in the partially occluded state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isoform SUR2B of ATP-binding cassette sub-family C member 9, ... | 著者 | Chen, L, Ding, D, Hou, T. | 登録日 | 2022-06-08 | 公開日 | 2023-06-14 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | 主引用文献 | The inhibition mechanism of the SUR2A-containing K ATP channel by a regulatory helix. Nat Commun, 14, 2023
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8IPT
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8IPS
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8IPR
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