PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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7PP1	Crystal structure of the P2Y12 receptor in complex with the inverse agonist selatogrel. 分子名称: CHOLESTEROL, P2Y purinoceptor 12,Soluble cytochrome b562,P2Y purinoceptor 12, Selatogrel 著者 Mac Sweeney, A, Tidten-Luksch, N. 登録日 2021-09-13 公開日 2022-11-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Inverse agonist efficacy of selatogrel blunts constitutive P2Y12 receptor signaling by inducing the inactive receptor conformation. Biochem Pharmacol, 206, 2022
7PZO	mite allergen Der p 3 from Dermatophagoides pteronyssinus 分子名称: SULFATE ION, mite allergen Der p 3 著者 Timofeev, V.I, Shevtsov, M.B, Abramchik, Y.A, Mikheeva, O.O, Kostromina, M.A, Lykoshin, D.D, Zayats, E.A, Zavriev, S.K, Esipov, R.S, Kuranova, I.P. 登録日 2021-10-13 公開日 2022-11-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural plasticity and thermal stability of the histone-like protein from Spiroplasma melliferum are due to phenylalanine insertions into the conservative scaffold. J.Biomol.Struct.Dyn., 36, 2018
1PC9	Crystal Structure of BnSP-6, a Lys49-Phospholipase A2 分子名称: BnSP-6 著者 Magro, A.J, Soares, A.M, Giglio, J.R, Fontes, M.R.M. 登録日 2003-05-16 公開日 2004-06-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A(2): quaternary structure and inhibition mechanism insights. Biochem.Biophys.Res.Commun., 311, 2003
7Q7K	JAK2 in complex with 4-(2-amino-8-methoxyquinazolin-6-yl)phenol 分子名称: 4-(2-azanyl-8-methoxy-quinazolin-6-yl)phenol, Tyrosine-protein kinase JAK2 著者 Rowland, P. 登録日 2021-11-09 公開日 2022-02-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism. J.Med.Chem., 65, 2022
7Q7L	JAK2 in complex with 4-(2-amino-8-{[(2S)-1-hydroxypropan-2-yl]amino}quinazolin-6-yl)-5-ethyl-2-fluorophenol 分子名称: 4-[2-azanyl-8-[[(2~{S})-1-oxidanylpropan-2-yl]amino]quinazolin-6-yl]-5-ethyl-2-fluoranyl-phenol, GLYCEROL, Tyrosine-protein kinase JAK2 著者 Rowland, P. 登録日 2021-11-09 公開日 2022-02-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism. J.Med.Chem., 65, 2022
7Q7I	JAK2 in complex with 4-{8-methoxy-2-[(1-methyl-1H-pyrazol-4-yl)amino]quinazolin-6-yl}phenol 分子名称: 4-[8-methoxy-2-[(1-methylpyrazol-4-yl)amino]quinazolin-6-yl]phenol, Tyrosine-protein kinase JAK2 著者 Rowland, P. 登録日 2021-11-09 公開日 2022-02-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism. J.Med.Chem., 65, 2022
7Q7W	JAK2 in complex with 4-(2-{[5-(dimethylamino)pentyl]amino}-8-{[(2S)-1-hydroxypropan-2-yl]amino}quinazolin-6-yl)-5-ethyl-2-fluorophenol 分子名称: 4-[2-[5-(dimethylamino)pentylamino]-8-[[(2~{S})-1-oxidanylpropan-2-yl]amino]quinazolin-6-yl]-5-ethyl-2-fluoranyl-phenol, Tyrosine-protein kinase JAK2 著者 Rowland, P. 登録日 2021-11-09 公開日 2022-02-02 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism. J.Med.Chem., 65, 2022
5EPD	Crystal structure of Glycerol Trinitrate Reductase XdpB from Agrobacterium sp. R89-1 (Apo form) 分子名称: Glycerol trinitrate reductase 著者 Kolenko, P, Zahradnik, J, Zuskova, I, Cerny, J, Palyzova, A, Kyslikova, E, Schneider, B. 登録日 2015-11-11 公開日 2016-11-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The crystal structure of XdpB, the bacterial old yellow enzyme, in an FMN-free form. PLoS ONE, 13, 2018
5WOV	Solution NMR structure of cyclotide MCoTI-I 分子名称: Two inhibitor peptide topologies 2 著者 Schroeder, C.I, Kwon, S. 登録日 2017-08-03 公開日 2018-08-08 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Targeted Delivery of Cyclotides via Conjugation to a Nanobody. ACS Chem. Biol., 13, 2018
8IFM	Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 2 分子名称: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ... 著者 Zhang, J.T, Jia, N. 登録日 2023-02-18 公開日 2024-01-17 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (2.92 Å) 主引用文献 Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system. Nat.Chem.Biol., 20, 2024
5WOW	Solution NMR structure of cyclotide MCoTI-I 分子名称: Two inhibitor peptide topologies 2 著者 Schroeder, C.I, Kwon, S. 登録日 2017-08-03 公開日 2018-08-08 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Targeted Delivery of Cyclotides via Conjugation to a Nanobody. ACS Chem. Biol., 13, 2018
8IFL	Cryo-EM structure of tetrameric SPARTA gRNA-ssDNA target complex in state 1 分子名称: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ... 著者 Zhang, J.T, Jia, N. 登録日 2023-02-18 公開日 2024-01-17 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (3.11 Å) 主引用文献 Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system. Nat.Chem.Biol., 20, 2024
8IFK	Cryo-EM structure of monomeric SPARTA gRNA-ssDNA target complex 分子名称: MAGNESIUM ION, Piwi domain-containing protein, TIR domain-containing protein, ... 著者 Zhang, J.T, Jia, N. 登録日 2023-02-18 公開日 2024-01-17 最終更新日 2024-04-10 実験手法 ELECTRON MICROSCOPY (2.54 Å) 主引用文献 Target ssDNA activates the NADase activity of prokaryotic SPARTA immune system. Nat.Chem.Biol., 20, 2024
7KTS	Negative stain EM structure of the human SAGA coactivator complex (TRRAP, core, splicing module) 分子名称: Ataxin-7, Isoform 3 of Transcription factor SPT20 homolog, STAGA complex 65 subunit gamma, ... 著者 Herbst, D.A, Esbin, M.N, Nogales, E. 登録日 2020-11-24 公開日 2021-11-10 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (19.09 Å) 主引用文献 Structure of the human SAGA coactivator complex. Nat.Struct.Mol.Biol., 28, 2021
1L63	ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME 著者 Nicholson, H, Matthews, B.W. 登録日 1991-05-06 公開日 1991-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991
5MR2	Crystal structure of red abalone VERL repeat 2 with linker at 2.5 A resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Vitelline envelope sperm lysin receptor 著者 Sadat Al-Hosseini, H, Raj, I, Nishimura, K, De Sanctis, D, Jovine, L. 登録日 2016-12-21 公開日 2017-06-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis of Egg Coat-Sperm Recognition at Fertilization. Cell, 169, 2017
5M7N	Crystal structure of NtrX from Brucella abortus in complex with ATP processed with the CrystalDirect automated mounting and cryo-cooling technology 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Nitrogen assimilation regulatory protein 著者 Cornaciu, I, Fernandez, I, Hoffmann, G, Carrica, M.C, Goldbaum, F.A, Marquez, J.A. 登録日 2016-10-28 公開日 2017-01-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Three-Dimensional Structure of Full-Length NtrX, an Unusual Member of the NtrC Family of Response Regulators. J. Mol. Biol., 429, 2017
7LF8	Fab 6D12 bound to ApoL2 NTD 分子名称: Apolipoprotein L2, Fab 6D12 heavy chain, Fab 6D12 light chain, ... 著者 Ultsch, M, Kirchhofer, D. 登録日 2021-01-15 公開日 2021-08-04 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structures of the ApoL1 and ApoL2 N-terminal domains reveal a non-classical four-helix bundle motif. Commun Biol, 4, 2021
7RNT	CRYSTAL STRUCTURE OF THE TYR45TRP MUTANT OF RIBONUCLEASE T1 IN A COMPLEX WITH 2'-ADENYLIC ACID 分子名称: ADENOSINE-2'-MONOPHOSPHATE, CALCIUM ION, RIBONUCLEASE T1 著者 Koellner, G, Grunert, H.-P, Landt, O, Saenger, W. 登録日 1991-08-20 公開日 1993-01-15 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the Tyr45Trp mutant of ribonuclease T1 in a complex with 2'-adenylic acid. Eur.J.Biochem., 201, 1991
1L55	ANALYSIS OF THE INTERACTION BETWEEN CHARGED SIDE CHAINS AND THE ALPHA-HELIX DIPOLE USING DESIGNED THERMOSTABLE MUTANTS OF PHAGE T4 LYSOZYME 分子名称: BETA-MERCAPTOETHANOL, CHLORIDE ION, LYSOZYME 著者 Nicholson, H, Matthews, B.W. 登録日 1991-05-06 公開日 1991-10-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Analysis of the interaction between charged side chains and the alpha-helix dipole using designed thermostable mutants of phage T4 lysozyme. Biochemistry, 30, 1991
7R0S	Structure of a cytosolic sulfotransferase of Anopheles gambiae (AGAP001425) in complex with vanillin 分子名称: 4-hydroxy-3-methoxybenzaldehyde, AGAP001425-PA, CHLORIDE ION, ... 著者 Esposito Verza, A, Miggiano, R, Rizzi, R, Rossi, F. 登録日 2022-02-02 公開日 2022-08-10 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Biochemical and structural analysis of a cytosolic sulfotransferase of the malaria vector Anopheles gambiae overexpressed in the reproductive tissues. Curr Res Struct Biol, 4, 2022
5N83	Structure of the distal domain of mouse adenovirus 2 fibre, methylmercury chloride derivative 分子名称: Fiber, MERCURY (II) ION 著者 Singh, A.K, van Raaij, M.J. 登録日 2017-02-22 公開日 2018-03-14 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Structure and N-acetylglucosamine binding of the distal domain of mouse adenovirus 2 fibre. J. Gen. Virol., 99, 2018
5YW2	Crystal structure of Adenine phosphoribosyltransferase from Francisella tularensis. 分子名称: Adenine phosphoribosyltransferase, CHLORIDE ION, MAGNESIUM ION, ... 著者 Pavithra, G.C, Ramagopal, U.A. 登録日 2017-11-28 公開日 2018-01-03 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Crystal structures of APRT from Francisella tularensis - an N-H···N hydrogen bond imparts adenine specificity in adenine phosporibosyltransferases. FEBS J., 285, 2018
7SCY	Nuc147 bound to single BRCT 分子名称: DNA (147-MER), Histone H2A, Histone H2B type 1-J, ... 著者 Muthurajan, U.M, Rudolph, J.R. 登録日 2021-09-29 公開日 2022-01-12 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer. Mol.Cell, 81, 2021
7SCZ	Nuc147 bound to multiple BRCTs 分子名称: DNA (147-MER), Histone H2A, Histone H2B type 1-J, ... 著者 Muthurajan, U.M, Rudolph, J. 登録日 2021-09-29 公開日 2022-01-19 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer. Mol.Cell, 81, 2021

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