PDB: 66478 件ウェブページステータス検索Chemie searchBIRD

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3LOK	Drug resistant cSrc kinase domain in complex with covalent inhibitor PD168393 分子名称: N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE, Proto-oncogene tyrosine-protein kinase Src 著者 Gruetter, C, Rode, H.B, Rauh, D. 登録日 2010-02-04 公開日 2010-12-22 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Characterization of irreversible kinase inhibitors by directly detecting covalent bond formation: a tool for dissecting kinase drug resistance Chembiochem, 11, 2010
3L7P	Crystal structure of SMU.1657c, Putative nitrogen regulatory protein PII from streptococcus mutans 分子名称: Putative nitrogen regulatory protein PII 著者 Fan, X.-X, Wang, K.-T, Su, X.-D. 登録日 2009-12-29 公開日 2010-12-29 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of SMU.1657c, Putative nitrogen regulatory protein PII from streptococcus mutans To be Published
3KHP	Crystal structure of a possible dehydrogenase from Mycobacterium tuberculosis at 2.3A resolution 分子名称: CHLORIDE ION, L(+)-TARTARIC ACID, MaoC family protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID), Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2009-10-30 公開日 2009-12-01 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Increasing the structural coverage of tuberculosis drug targets. Tuberculosis (Edinb), 95, 2015
3KM6	Crystal Structure of the Human GST Pi C47S/Y108V Double Mutant in Complex with the Ethacrynic Acid-Glutathione Conjugate 分子名称: CALCIUM ION, ETHACRYNIC ACID, GLUTATHIONE, ... 著者 Parker, L.J. 登録日 2009-11-10 公開日 2010-03-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Diuretic drug binding to human glutathione transferase P1-1: potential role of Cys-101 revealed in the double mutant C47S/Y108V. J.Mol.Recognit., 24
3KOB	DTD from Plasmodium falciparum in complex with D-Glutamic acid 分子名称: D-GLUTAMIC ACID, D-tyrosyl-tRNA(Tyr) deacylase 著者 Manickam, Y, Bhatt, T.K, Sharma, A. 登録日 2009-11-13 公開日 2009-12-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase J.Biol.Chem., 285, 2010
3KEK	Crystal Structure of Human MMP-13 complexed with a (pyridin-4-yl)-2H-tetrazole compound 分子名称: CALCIUM ION, Collagenase 3, ZINC ION, ... 著者 Shieh, H.-S, Collins, B, Schnute, M.E. 登録日 2009-10-26 公開日 2010-11-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Discovery of (pyridin-4-yl)-2H-tetrazole as a novel scaffold to identify highly selective matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis. Bioorg.Med.Chem.Lett., 20, 2009
3KHC	Crystal Structure of Escherichia coli AlkB in complex with ssDNA containing a 1-methylguanine lesion 分子名称: 2-OXOGLUTARIC ACID, Alpha-ketoglutarate-dependent dioxygenase alkB, COBALT (II) ION, ... 著者 Hollis, T, Holland, P.J. 登録日 2009-10-30 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and mutational analysis of Escherichia coli AlkB provides insight into substrate specificity and DNA damage searching. Plos One, 5, 2010
3KOC	DTD from Plasmodium falciparum in complex with D-Histidine 分子名称: D-HISTIDINE, D-tyrosyl-tRNA(Tyr) deacylase 著者 Manickam, Y, Bhatt, T.K, Sharma, A. 登録日 2009-11-13 公開日 2009-12-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 Ligand-bound Structures Provide Atomic Snapshots for the Catalytic Mechanism of D-Amino Acid Deacylase J.Biol.Chem., 285, 2010
3I0J	Crystal structure of GTB C80S/C196S/C209S + H antigen 分子名称: ABO glycosyltransferase, alpha-L-fucopyranose-(1-2)-hexyl beta-D-galactopyranoside 著者 Schuman, B, Persson, M, Landry, R.C, Polakowski, R, Weadge, J.T, Seto, N.O.L, Borisova, S, Palcic, M.M, Evans, S.V. 登録日 2009-06-25 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Cysteine-to-serine mutants dramatically reorder the active site of human ABO(H) blood group B glycosyltransferase without affecting activity: structural insights into cooperative substrate binding. J.Mol.Biol., 402, 2010
3I1C	Crystal Structure of a Novel Engineered Diels-Alderase: DA_20_00_A74I 分子名称: Diisopropyl-fluorophosphatase, GLYCEROL 著者 Lambert, A.R, Stoddard, B.L. 登録日 2009-06-26 公開日 2009-08-18 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction. Science, 329, 2010
3I5W	Crystal structure of human alpha-defensin 5 (mutant R13H) 分子名称: CHLORIDE ION, CITRATE ANION, Defensin-5 著者 Pazgier, M, Lu, W. 登録日 2009-07-06 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Selective arginines are important for the antibacterial activity and host cell interaction of human alpha-defensin 5 Febs Lett., 583, 2009
3IHZ	Crystal structure of the FK506 binding domain of Plasmodium vivax FKBP35 in complex with FK506 分子名称: 70 kDa peptidylprolyl isomerase, putative, 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN 著者 Qureshi, I.A, Alag, R, Yoon, H.S, Lescar, J. 登録日 2009-07-31 公開日 2010-06-16 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 NMR and crystallographic structures of the FK506 binding domain of human malarial parasite Plasmodium vivax FKBP35 Protein Sci., 19, 2010
3IWY	Crystal structure of human MDM2 complexed with D-peptide (12 residues) 分子名称: D-peptide inhibitor, E3 ubiquitin-protein ligase Mdm2 著者 Pazgier, M, Lu, W. 登録日 2009-09-03 公開日 2010-04-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 D-peptide inhibitors of the p53-MDM2 interaction for targeted molecular therapy of malignant neoplasms. Proc.Natl.Acad.Sci.USA, 398, 2010
3GJP	Crystal structure of mutant coiled coil GCN4 leucine zipper 分子名称: General control protein GCN4 著者 Honnappa, S, Steinmetz, M.O. 登録日 2009-03-09 公開日 2010-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Molecular basis of coiled-coil oligomerization-state specificity Proc.Natl.Acad.Sci.USA, 107, 2010
3GNU	Toxin fold as basis for microbial attack and plant defense 分子名称: 25 kDa protein elicitor, CHLORIDE ION, GUANIDINE 著者 Ottmann, C, Luberacki, B, Kuefner, I, Koch, W, Brunner, F, Weyand, M, Mattinen, L, Pirhonen, M, Anderluh, G, Seitz, H.U, Nuernberger, T, Oecking, C. 登録日 2009-03-18 公開日 2009-06-09 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A common toxin fold mediates microbial attack and plant defense Proc.Natl.Acad.Sci.USA, 106, 2009
3LO1	Crystal structure of human alpha-defensin 1 (Y16A mutant) 分子名称: 2-(2-METHOXYETHOXY)ETHANOL, AZIDE ION, Neutrophil defensin 1 著者 Pazgier, M, Lu, W. 登録日 2010-02-03 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010
3LOG	Crystal structure of MbtI from Mycobacterium tuberculosis 分子名称: CARBONATE ION, GLYCEROL, Isochorismate synthase/isochorismate-pyruvate lyase mbtI, ... 著者 Bulloch, E.M.M, Lott, J.S, Baker, E.N, Johnston, J.M. 登録日 2010-02-03 公開日 2011-02-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Inhibition studies of Mycobacterium tuberculosis salicylate synthase (MbtI). Chemmedchem, 5, 2010
3LNZ	Crystal structure of human MDM2 with a 12-mer peptide inhibitor PMI (N8A mutant) 分子名称: 12-mer peptide inhibitor, CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2 著者 Pazgier, M, Lu, W. 登録日 2010-02-03 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Systematic mutational analysis of peptide inhibition of the p53-MDM2/MDMX interactions. J.Mol.Biol., 398, 2010
3LOE	Crystal structure of human alpha-defensin 1 (F28A mutant) 分子名称: GLYCEROL, Neutrophil defensin 1, SULFATE ION 著者 Pazgier, M, Lu, W. 登録日 2010-02-03 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285, 2010
3L7O	Crystal structure of Ribose-5-phosphate isomerase A from streptococcus mutans UA159 分子名称: Ribose-5-phosphate isomerase A 著者 Fan, X.X, Wang, K.T, Su, X.D. 登録日 2009-12-29 公開日 2011-01-05 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of Ribose-5-phosphate isomerase A from streptococcus mutans UA159 TO BE PUBLISHED
3H1G	Crystal structure of Chey mutant T84A of helicobacter pylori 分子名称: Chemotaxis protein cheY homolog, MAGNESIUM ION, SULFATE ION 著者 Lam, K.H, Ling, T.K, Au, S.W. 登録日 2009-04-12 公開日 2010-03-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of activated CheY1 from Helicobacter pylori. J.Bacteriol., 192, 2010
3LA2	Crystal structure of NtcA in complex with 2-oxoglutarate 分子名称: 2-OXOGLUTARIC ACID, Global nitrogen regulator 著者 Zhao, M.X, Jiang, Y.L, He, Y.X, Chen, Y.F, Teng, Y.B, Chen, Y.X, Zhang, C.C, Zhou, C.Z. 登録日 2010-01-06 公開日 2010-07-14 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for the allosteric control of the global transcription factor NtcA by the nitrogen starvation signal 2-oxoglutarate. Proc.Natl.Acad.Sci.USA, 107, 2010
3GRR	Crystal Structure of the complex between S-Adenosyl Homocysteine and Methanocaldococcus jannaschi Dim1. 分子名称: Dimethyladenosine transferase, S-ADENOSYL-L-HOMOCYSTEINE 著者 Scarsdale, J.N, Musayev, F.N, Rife, J.P. 登録日 2009-03-26 公開日 2010-03-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design. Biochemistry, 49, 2010
3GRV	Crystal Structure of the Complex between Adenosine and Methanocaldococcus jannaschi Dim1 分子名称: ADENOSINE, Dimethyladenosine transferase, SULFATE ION 著者 Scarsdale, J.N, Musayev, F.N, Rife, J.P. 登録日 2009-03-26 公開日 2010-03-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design. Biochemistry, 49, 2010
3LA9	Crystal structure of the trimeric autotransporter adhesin head domain BpaA from Burkholderia pseudomallei, iodide phased 分子名称: Haemagglutinin family protein, IODIDE ION 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2010-01-06 公開日 2010-05-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure of a Burkholderia pseudomallei trimeric autotransporter adhesin head. Plos One, 5, 2010

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