PDB: 95574 件ウェブページステータス検索Chemie searchBIRD

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2BYR	CRYSTAL STRUCTURE OF ACHBP FROM APLYSIA CALIFORNICA in complex with methyllycaconitine 分子名称: ACETYLCHOLINE-BINDING PROTEIN, METHYLLYCACONITINE 著者 Hansen, S.B, Sulzenbacher, G, Huxford, T, Marchot, P, Taylor, P, Bourne, Y. 登録日 2005-08-03 公開日 2005-10-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations. Embo J., 24, 2005
1O1R	Structure of FPT bound to GGPP 分子名称: GERANYLGERANYL DIPHOSPHATE, Protein farnesyltransferase alpha subunit, Protein farnesyltransferase beta subunit, ... 著者 Turek-Etienne, T.C, Strickland, C.L, Distefano, M.D. 登録日 2003-01-14 公開日 2003-05-06 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Biochemical and Structural Studies with Prenyl Diphosphate Analogues Provide Insights into Isoprenoid Recognition by Protein Farnesyl Transferase Biochemistry, 42, 2003
1NTZ	Crystal Structure of Mitochondrial Cytochrome bc1 Complex Bound with Ubiquinone 分子名称: Cytochrome b, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Gao, X, Wen, X, Esser, L, Quinn, B, Yu, L, Yu, C.-A, Xia, D. 登録日 2003-01-30 公開日 2003-10-07 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site Biochemistry, 42, 2003
6TT3	Crystal structure of 'Res_S2 mutant human Angiotensin-1 converting enzyme N-domain in complex with SG6. 分子名称: (2~{S})-1-[(2~{S})-2-[[(1~{S})-1-[(2~{S})-1-[(2~{S})-2-azanyl-4-oxidanyl-4-oxidanylidene-butanoyl]pyrrolidin-2-yl]-2-oxidanyl-2-oxidanylidene-ethyl]amino]propanoyl]pyrrolidine-2-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cozier, G.E, Acharya, K.R. 登録日 2019-12-23 公開日 2020-04-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 ACE-domain selectivity extends beyond direct interacting residues at the active site. Biochem.J., 477, 2020
1O34	Elaborate Manifold of Short Hydrogen Bond Arrays Mediating Binding of Active Site-Directed Serine Protease Inhibitors 分子名称: 2-{5-[AMINO(IMINIO)METHYL]-1H-BENZIMIDAZOL-2-YL}PYRIDIN-3-OLATE, BETA-TRYPSIN, CALCIUM ION, ... 著者 Katz, B.A, Elrod, K, Verner, E, Mackman, R.L, Luong, C, Shrader, W.D, Sendzik, M, Spencer, J.R, Sprengeler, P.A, Kolesnikov, A, Tai, V.W, Hui, H.C, Breitenbucher, J.G, Allen, D, Janc, J.W. 登録日 2003-03-06 公開日 2003-09-02 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Elaborate manifold of short hydrogen bond arrays mediating binding of active site-directed serine protease inhibitors. J.Mol.Biol., 329, 2003
8IG4	Crystal structure of SARS-Cov-2 main protease in complex with GC376 分子名称: Non-structural protein 11, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide 著者 Zhou, X.L, Zhang, J, Li, J. 登録日 2023-02-20 公開日 2024-03-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376. J.Mol.Biol., 436, 2024
8IG6	Crystal structure of MERS main protease in complex with GC376 分子名称: N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide, ORF1a 著者 Lin, C, Zhang, J, Li, J. 登録日 2023-02-20 公開日 2024-03-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376. J.Mol.Biol., 436, 2024
8IGA	Crystal structure of SARS-Cov-2 main protease K90R mutant in complex with GC376 分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide 著者 Wang, J, Zhang, J, Li, J. 登録日 2023-02-20 公開日 2024-03-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.63 Å) 主引用文献 Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376. J.Mol.Biol., 436, 2024
6TT1	Crystal structure of 'Res_S2 mutant human Angiotensin-1 converting enzyme N-domain in complex with 33RE. 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cozier, G.E, Acharya, K.R. 登録日 2019-12-23 公開日 2020-04-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 ACE-domain selectivity extends beyond direct interacting residues at the active site. Biochem.J., 477, 2020
8IG7	Crystal structure of SARS-Cov-2 main protease G15S mutant in complex with GC376 分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide 著者 Zeng, P, Zhang, J, Li, J. 登録日 2023-02-20 公開日 2024-03-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376. J.Mol.Biol., 436, 2024
8IG5	Crystal structure of SARS main protease in complex with GC376 分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide 著者 Lin, C, Zhang, J, Li, J. 登録日 2023-02-20 公開日 2024-03-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376. J.Mol.Biol., 436, 2024
1NTK	Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Antimycin A1 分子名称: Cytochrome b, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Gao, X, Wen, X, Esser, L, Quinn, B, Yu, L, Yu, C.-A, Xia, D. 登録日 2003-01-30 公開日 2003-10-07 最終更新日 2016-03-16 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site Biochemistry, 42, 2003
8IG9	Crystal structure of SARS-Cov-2 main protease M49I mutant in complex with GC376 分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide 著者 Zou, X.F, Zhang, J, Li, J. 登録日 2023-02-20 公開日 2024-03-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376. J.Mol.Biol., 436, 2024
8IG8	Crystal structure of SARS-Cov-2 main protease S46F mutant in complex with GC376 分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide 著者 Zeng, X.Y, Zhang, J, Li, J. 登録日 2023-02-20 公開日 2024-03-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376. J.Mol.Biol., 436, 2024
8IGB	Crystal structure of SARS-Cov-2 main protease P132H mutant in complex with GC376 分子名称: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide 著者 Li, W.W, Zhang, J, Li, J. 登録日 2023-02-20 公開日 2024-03-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Structural Basis for Coronaviral Main Proteases Inhibition by the 3CLpro Inhibitor GC376. J.Mol.Biol., 436, 2024
1O05	Apo form of human mitochondrial aldehyde dehydrogenase 分子名称: Aldehyde dehydrogenase, SODIUM ION 著者 Hurley, T.D, Perez-Miller, S, Breen, H. 登録日 2003-02-20 公開日 2003-03-04 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Order and disorder in mitochondrial aldehyde dehydrogenase Chem.Biol.Interact., 130-132, 2001
1NMB	THE STRUCTURE OF A COMPLEX BETWEEN THE NC10 ANTIBODY AND INFLUENZA VIRUS NEURAMINIDASE AND COMPARISON WITH THE OVERLAPPING BINDING SITE OF THE NC41 ANTIBODY 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, FAB NC10, ... 著者 Malby, R.L, Tulip, W.R, Colman, P.M. 登録日 1995-01-17 公開日 1995-09-15 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The structure of a complex between the NC10 antibody and influenza virus neuraminidase and comparison with the overlapping binding site of the NC41 antibody Structure, 2, 1994
2VCM	Isopenicillin N synthase with substrate analogue AsMCOV 分子名称: FE (II) ION, ISOPENICILLIN N SYNTHETASE, N^6^-[(1R,2S)-1-({[(1R)-1-carboxy-2-methylpropyl]oxy}carbonyl)-2-sulfanylpropyl]-6-oxo-L-lysine, ... 著者 Ge, W, Clifton, I.J, Adlington, R.M, Baldwin, J.E, Rutledge, P.J. 登録日 2007-09-25 公開日 2008-11-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural Studies on the Reaction of Isopenicillin N Synthase with a Sterically Demanding Depsipeptide Substrate Analogue. Chembiochem, 10, 2009
6TT4	Crystal structure of 'Res_S2 mutant human Angiotensin-1 converting enzyme N-domain in complex with omapatrilat. 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Cozier, G.E, Acharya, K.R. 登録日 2019-12-23 公開日 2020-04-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 ACE-domain selectivity extends beyond direct interacting residues at the active site. Biochem.J., 477, 2020
8RZX	Solution structure of a parallel stranded G-quadruplex formed in ORAI1 promoter 分子名称: DNA (5'-D(*TP*GP*GP*GP*CP*GP*GP*GP*GP*CP*AP*CP*AP*GP*GP*TP*GP*GP*GP*CP*GP*GP*GP*G)-3') 著者 Jana, J, Weisz, K. 登録日 2024-02-13 公開日 2024-08-21 最終更新日 2024-09-11 実験手法 SOLUTION NMR 主引用文献 Remodeling Ca 2+ dynamics by targeting a promising E-box containing G-quadruplex at ORAI1 promoter in triple-negative breast cancer. Cell Calcium, 123, 2024
8RD6	the C-terminal domain of TonB protein from Salmonella enterica. 分子名称: Protein TonB 著者 Iwai, H, Ciragan, A, Oeemig, J.S. 登録日 2023-12-07 公開日 2024-01-17 実験手法 SOLUTION NMR 主引用文献 The 100-protein NMR spectra dataset: A resource for biomolecular NMR data analysis. Sci Data, 11, 2024
2VLI	Structure of Deinococcus radiodurans tunicamycin resistance protein 分子名称: ANTIBIOTIC RESISTANCE PROTEIN, CADMIUM ION, CHLORIDE ION 著者 Macedo, S, Kapp, U, Leiros, I, Hall, D.R, Mitchell, E. 登録日 2008-01-15 公開日 2008-06-17 最終更新日 2019-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure of Deinococcus Radiodurans Tunicamycin-Resistance Protein (Tmrd), a Phosphotransferase. Acta Crystallogr.,Sect.F, 64, 2008
2VE1	Isopenicillin N synthase with substrate analogue AsMCOV (oxygen exposed 1min 20bar) 分子名称: FE (II) ION, ISOPENICILLIN N SYNTHETASE, N^6^-[(1R,2S)-1-({[(1R)-1-carboxy-2-methylpropyl]oxy}carbonyl)-2-sulfanylpropyl]-6-oxo-L-lysine, ... 著者 Ge, W, Clifton, I.J, Adlington, R.M, Baldwin, J.E, Rutledge, P.J. 登録日 2007-10-15 公開日 2008-11-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural Studies on the Reaction of Isopenicillin N Synthase with a Sterically Demanding Depsipeptide Substrate Analogue. Chembiochem, 10, 2009
8HST	The structure of rat beta-arrestin1 分子名称: Beta-arrestin-1 著者 Yun, Y, Yoon, H.J, Choi, Y, Lee, H.H. 登録日 2022-12-20 公開日 2023-07-19 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 GPCR targeting of E3 ubiquitin ligase MDM2 by inactive beta-arrestin. Proc.Natl.Acad.Sci.USA, 120, 2023
8HSV	The structure of rat beta-arrestin1 in complex with a rat Mdm2 peptide 分子名称: Beta-arrestin-1, SULFATE ION, peptide from E3 ubiquitin-protein ligase Mdm2 著者 Yun, Y, Yoon, H.J, Choi, Y, Lee, H.H. 登録日 2022-12-20 公開日 2023-07-19 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 GPCR targeting of E3 ubiquitin ligase MDM2 by inactive beta-arrestin. Proc.Natl.Acad.Sci.USA, 120, 2023

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