5UVL
 
 | | Serial Millisecond Crystallography of Membrane and Soluble Protein Micro-crystals using Synchrotron Radiation | | 分子名称: | CALCIUM ION, NITRATE ION, Proteinase K | | 著者 | Martin-Garcia, J.M, Conrad, C.E, Nelson, G, Stander, N, Zatsepin, N.A, Zook, J, Zhu, L, Geiger, J, Chun, E, Kissick, D, Hilgart, M.C, Ogata, C, Ishchenko, A, Nagaratnam, N, Roy-Chowdhury, S, Coe, J, Subramanian, G, Schaffer, A, James, D, Ketawala, G, Venugopalan, N, Xu, S, Corcoran, S, Ferguson, D, Weierstall, U, Spence, J.C.H, Cherezov, V, Fromme, P, Fischetti, R.F, Liu, W. | | 登録日 | 2017-02-20 | | 公開日 | 2017-05-24 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation.
IUCrJ, 4, 2017
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6E2N
 | | ASK1 kinase domain complex with inhibitor | | 分子名称: | Mitogen-activated protein kinase kinase kinase 5, N-[3-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)phenyl][3,4'-bipyridine]-2'-carboxamide | | 著者 | Lansdon, E.B. | | 登録日 | 2018-07-11 | | 公開日 | 2018-09-19 | | 最終更新日 | 2018-10-17 | | 実験手法 | X-RAY DIFFRACTION (2.098 Å) | | 主引用文献 | ASK1 contributes to fibrosis and dysfunction in models of kidney disease.
J. Clin. Invest., 128, 2018
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5V3J
 | | mouseZFP568-ZnF1-10 in complex with DNA | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (26-MER), MAGNESIUM ION, ... | | 著者 | Patel, A, Cheng, X. | | 登録日 | 2017-03-07 | | 公開日 | 2018-03-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.064 Å) | | 主引用文献 | DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins.
Cell, 173, 2018
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4ZFX
 | | Siderocalin-mediated recognition and cellular uptake of actinides | | 分子名称: | N,N',N''-[(3S,7S,11S)-2,6,10-trioxo-1,5,9-trioxacyclododecane-3,7,11-triyl]tris(2,3-dihydroxybenzamide), Neutrophil gelatinase-associated lipocalin, SULFATE ION, ... | | 著者 | Allred, B.E, Rupert, P.B, Gauny, S.S, An, D.D, Ralston, C.Y, Sturzbecher-Hoehne, M, Strong, R.K, Abergel, R.J. | | 登録日 | 2015-04-22 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides.
Proc.Natl.Acad.Sci.USA, 112, 2015
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6E2J
 | | Crystal structure of the heterocomplex between human keratin 1 coil 1B containing S233L mutation and wild-type human keratin 10 coil 1B | | 分子名称: | Keratin, type I cytoskeletal 10, type II cytoskeletal 1, ... | | 著者 | Eldirany, S.A, Lomakin, I.B, Bunick, C.G. | | 登録日 | 2018-07-11 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.386 Å) | | 主引用文献 | Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly.
Embo J., 38, 2019
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7SH5
 | | Crystal structure of CYP142A3 from Mycobacterium ulcerans bound to Cholest-4-en-3-one | | 分子名称: | (8ALPHA,9BETA)-CHOLEST-4-EN-3-ONE, ACETATE ION, Cytochrome P450 142A3, ... | | 著者 | Doherty, D.Z, Bell, S.G, Bruning, J. | | 登録日 | 2021-10-08 | | 公開日 | 2022-10-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | The Structures of the Steroid Binding CYP142 Cytochrome P450 Enzymes from Mycobacterium ulcerans and Mycobacterium marinum.
Acs Infect Dis., 8, 2022
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6E2O
 | | ASK1 kinase domain complex with inhibitor | | 分子名称: | 4-(4-cyclopropyl-1H-imidazol-1-yl)-N-[3-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)phenyl]pyridine-2-carboxamide, Mitogen-activated protein kinase kinase kinase 5 | | 著者 | Lansdon, E.B. | | 登録日 | 2018-07-11 | | 公開日 | 2018-09-19 | | 最終更新日 | 2018-10-17 | | 実験手法 | X-RAY DIFFRACTION (2.389 Å) | | 主引用文献 | ASK1 contributes to fibrosis and dysfunction in models of kidney disease.
J. Clin. Invest., 128, 2018
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4POL
 | | Crystal structures of thioredoxin with mesna at 2.8A resolution | | 分子名称: | 1-THIOETHANESULFONIC ACID, Thioredoxin | | 著者 | Sridhar, V, Chie-Leon, B, Badger, J, Nienaber, V.L, Hausheer, F.H. | | 登録日 | 2014-02-26 | | 公開日 | 2014-10-29 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | BNP7787 Forms Novel Covalent
Adducts on Human Thioredoxin
and Modulates Thioredoxin
Activity
J Pharmacol Clin Toxicol, 2, 2014
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4POU
 | | VHH-metal in Complex with RNase A | | 分子名称: | Ribonuclease pancreatic, VHH Antibody | | 著者 | Fanning, S.W, Walter, R, Horn, J.R. | | 登録日 | 2014-02-26 | | 公開日 | 2014-09-24 | | 最終更新日 | 2014-10-22 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural basis of an engineered dual-specific antibody: conformational diversity leads to a hypervariable loop metal-binding site.
Protein Eng.Des.Sel., 27, 2014
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8UCT
 | | Crystal structure of TcPINK1 in complex with PRT | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-{[3-(2H-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide, SULFATE ION, ... | | 著者 | Veyron, S, Rasool, S, Trempe, J.F. | | 登録日 | 2023-09-27 | | 公開日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.93 Å) | | 主引用文献 | Characterization of a new family of PINK1 inhibitors
To Be Published
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6EC0
 | | Crystal structure of the wild-type heterocomplex between coil 1B domains of human intermediate filament proteins keratin 1 (KRT1) and keratin 10 (KRT10) | | 分子名称: | CADMIUM ION, COBALT (II) ION, Keratin 1, ... | | 著者 | Eldirany, S.A, Lomakin, I.B, Bunick, C.G. | | 登録日 | 2018-08-07 | | 公開日 | 2019-05-15 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.983 Å) | | 主引用文献 | Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly.
Embo J., 38, 2019
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6RAA
 | | CLK1 Kinase domain with bound imidazopyridin inhibitor TP003 | | 分子名称: | 1,2-ETHANEDIOL, 4-[2-methyl-1-(4-methylpiperazin-1-yl)-1-oxidanylidene-propan-2-yl]-~{N}-(6-pyridin-4-ylimidazo[1,2-a]pyridin-2-yl)benzamide, Dual specificity protein kinase CLK1 | | 著者 | Schroeder, M, Arrowsmith, C, Knapp, S, Bountra, C, Edwards, A, Structural Genomics Consortium (SGC) | | 登録日 | 2019-04-05 | | 公開日 | 2019-04-24 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | CLK1 Kinase domain with bound imidazopyridin inhibitor TP003
To Be Published
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4ZAR
 | | Crystal Structure of Proteinase K from Engyodontium albuminhibited by METHOXYSUCCINYL-ALA-ALA-PRO-PHE-CHLOROMETHYL KETONE at 1.15 A resolution | | 分子名称: | CALCIUM ION, METHOXYSUCCINYL-ALA-ALA-PRO-PHE-CHLOROMETHYL KETONE, bound form, ... | | 著者 | Sawaya, M.R, Cascio, D, Collazo, M, Bond, C, Cohen, A, DeNicola, A, Eden, K, Jain, K, Leung, C, Lubock, N, McCormick, J, Rosinski, J, Spiegelman, L, Athar, Y, Tibrewal, N, Winter, J, Solomon, S. | | 登録日 | 2015-04-14 | | 公開日 | 2015-05-06 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Crystal Structure of Proteinase K from Engyodontium album inhibited by METHOXYSUCCINYL-ALA-ALA-PRO-PHE-CHLOROMETHYL KETONE at 1.15 A resolution
to be published
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4ZIX
 | | Structure of HEWL using Serial Femtosecond Crystallography of Soluble Proteins in Lipidic Cubic Phase | | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | | 著者 | Fromme, R, Ishchenko, A, Metz, M, Roy-Chowdhury, S, Basu, S, Boutet, S, Fromme, P, White, T.A, Barty, A, Spence, J.C.H, Weierstall, U, Liu, W, Cherezov, V. | | 登録日 | 2015-04-28 | | 公開日 | 2015-08-12 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Serial Femtosecond Crystallography of Soluble Proteins in Lipidic Cubic Phase
IUCrJ, 2, 2015
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5UND
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7S27
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7S29
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4PRQ
 | | CRYSTAL STRUCTURE OF HEN EGG-WHITE LYSOZYME IN COMPLEX WITH SCLX4 AT 1.72 A RESOLUTION | | 分子名称: | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, 25,26,27,28-tetrahydroxypentacyclo[19.3.1.1~3,7~.1~9,13~.1~15,19~]octacosa-1(25),3(28),4,6,9(27),10,12,15(26),16,18,21,23-dodecaene-5,11,17,23-tetrasulfonic acid, HEXAETHYLENE GLYCOL, ... | | 著者 | McGovern, R.E, McCarthy, A.A, Crowley, P.B. | | 登録日 | 2014-03-06 | | 公開日 | 2014-09-10 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Protein assembly mediated by sulfonatocalix[4]arene.
Chem.Commun.(Camb.), 50, 2014
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7S2C
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7S30
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7S33
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8UO7
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8UN4
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7S2W
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7S2A
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