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4IEA
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14-3-3 isoform sigma in complex with a phosphorylated C-RAF peptide
分子名称: 14-3-3 protein sigma, RAF proto-oncogene serine/threonine-protein kinase
著者Molzan, M, Ottmann, C.
登録日2012-12-13
公開日2013-09-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Stabilization of Physical RAF/14-3-3 Interaction by Cotylenin A as Treatment Strategy for RAS Mutant Cancers.
Acs Chem.Biol., 8, 2013
4IOF
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BU of 4iof by Molmil
Crystal structure analysis of Fab-bound human Insulin Degrading Enzyme (IDE)
分子名称: Fab-bound IDE, heavy chain, light chain, ...
著者McCord, L.A, Liang, W.G, Hoey, R, Dowdell, E, Koide, A, Koide, S, Tang, W.J.
登録日2013-01-07
公開日2013-07-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.353 Å)
主引用文献Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme.
Proc.Natl.Acad.Sci.USA, 110, 2013
4IOS
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BU of 4ios by Molmil
Structure of phage TP901-1 RBP (ORF49) in complex with nanobody 11.
分子名称: BPP, GLYCEROL, Llama nanobody 11
著者Desmyter, A, Farenc, C, Mahony, J, Spinelli, S, Bebeacua, C, Blangy, S, Veesler, D, van Sinderen, D, Cambillau, C.
登録日2013-01-08
公開日2013-03-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Viral infection modulation and neutralization by camelid nanobodies
Proc.Natl.Acad.Sci.USA, 110, 2013
2MUG
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BU of 2mug by Molmil
Protective cellular immunity against P. falciparum malaria merozoite is associated with a different P7 and P8 residue orientation in the MHC-peptide-TCR complex
分子名称: Serine-repeat antigen protein
著者Patarroyo, M, Salazar, L, Cifuentes, G, Lozano, J, Delgado, G, Rivera, Z, Rosas, J, Vargas, L.
登録日2014-09-09
公開日2014-10-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Protective cellular immunity against P. falciparum malaria merozoites is associated with a different P7 and P8 residue orientation in the MHC-peptide-TCR complex.
Biochimie, 88, 2006
6VSB
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BU of 6vsb by Molmil
Prefusion 2019-nCoV spike glycoprotein with a single receptor-binding domain up
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Wrapp, D, Wang, N, Corbett, K.S, Goldsmith, J.A, Hsieh, C, Abiona, O, Graham, B.S, McLellan, J.S.
登録日2020-02-10
公開日2020-02-26
最終更新日2021-01-27
実験手法ELECTRON MICROSCOPY (3.46 Å)
主引用文献Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.
Science, 367, 2020
3OC5
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Crystal Structure of the vibrio cholerae secreted colonization factor TcpF
分子名称: Toxin coregulated pilus biosynthesis protein F
著者Craig, L, Kolappan, S, Yuen, A.S.W.
登録日2010-08-09
公開日2011-04-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of the Vibrio cholerae Colonization Factor TcpF and Identification of a Functional Immunogenic Site.
J.Mol.Biol., 409, 2011
3OC8
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Crystal Structure of the C-terminal Domain of the Vibrio cholerae soluble colonization factor TcpF
分子名称: 1,4-DIETHYLENE DIOXIDE, GLYCEROL, SULFATE ION, ...
著者Craig, L, Kolappan, S, Yuen, A.S.W.
登録日2010-08-09
公開日2011-04-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the Vibrio cholerae Colonization Factor TcpF and Identification of a Functional Immunogenic Site.
J.Mol.Biol., 409, 2011
4UX8
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RET recognition of GDNF-GFRalpha1 ligand by a composite binding site promotes membrane-proximal self-association
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF FAMILY RECEPTOR ALPHA-1, ...
著者Goodman, K, Kjaer, S, Beuron, F, Knowles, P, Nawrotek, A, Burns, E, Purkiss, A, George, R, Santoro, M, Morris, E.P, McDonald, N.Q.
登録日2014-08-19
公開日2014-10-01
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (24 Å)
主引用文献Ret Recognition of Gdnf-Gfralpha1 Ligand by a Composite Binding Site Promotes Membrane-Proximal Self-Association.
Cell Rep., 8, 2014
4V86
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Structure-function Analysis of Receptor-binding in Adeno-Associated Virus Serotype 6 (AAV-6)
分子名称: Capsid protein VP1
著者Xie, Q.
登録日2011-09-13
公開日2014-07-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.003 Å)
主引用文献Structure-function analysis of receptor-binding in adeno-associated virus serotype 6 (AAV-6).
Virology, 420, 2011
1TCR
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BU of 1tcr by Molmil
MURINE T-CELL ANTIGEN RECEPTOR 2C CLONE
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Garcia, K.C, Degano, M, Stanfield, R.L, Wilson, I.A.
登録日1996-09-12
公開日1997-03-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex.
Science, 274, 1996
1T2J
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BU of 1t2j by Molmil
Crystal structure of a Human VH domain
分子名称: DI(HYDROXYETHYL)ETHER, M12-Variable Heavy domain
著者Gaur, R.K, Fischer, R, Hoffmann, K.M.V.
登録日2004-04-21
公開日2005-05-03
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of a human VH domain at 1.5 angstrom
To be Published
5HCG
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BU of 5hcg by Molmil
CRYSTAL STRUCTURE OF FREE-CODV.
分子名称: CODV heavy-chain, CODV light chain
著者Vallee, F, Dupuy, A, Rak, A.
登録日2016-01-04
公開日2016-03-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献CODV-Ig, a universal bispecific tetravalent and multifunctional immunoglobulin format for medical applications.
Mabs, 8, 2016
5V8O
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BU of 5v8o by Molmil
Discovery of a high affinity inhibitor of cGAS
分子名称: 5-phenyltetrazolo[1,5-a]pyrimidin-7-ol, Cyclic GMP-AMP synthase, ZINC ION
著者Hall, J.
登録日2017-03-22
公開日2017-09-27
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay.
PLoS ONE, 12, 2017
8A58
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BU of 8a58 by Molmil
X-ray structure of TRIM21 RING E3 ligase in complex with E2 enzyme Ube2W
分子名称: E3 ubiquitin-protein ligase TRIM21, Ubiquitin-conjugating enzyme E2 W, ZINC ION
著者James, L.C, Kiss, L.
登録日2022-06-14
公開日2023-04-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates.
Nat Commun, 14, 2023
3T1P
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BU of 3t1p by Molmil
Crystal structure of an alpha-1-antitrypsin trimer
分子名称: Alpha-1-antitrypsin
著者Huntington, J.A, Yamasaki, M.
登録日2011-07-22
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Molecular basis of alpha 1-antitrypsin deficiency revealed by the structure of a domain-swapped trimer.
EMBO Rep., 12, 2011
3S96
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BU of 3s96 by Molmil
Crystal structure of 3B5H10
分子名称: 3B5H10 FAB heavy chain, 3B5H10 FAB light chain
著者Weisgraber, K, Peters-Libeu, C, Rutenber, E, Newhouse, Y, Finkbeiner, S.
登録日2011-05-31
公開日2012-02-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure.
J.Mol.Biol., 421, 2012
3VI4
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BU of 3vi4 by Molmil
Crystal structure of alpha5beta1 integrin headpiece in complex with RGD peptide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Nagae, M, Nogi, T, Takagi, J.
登録日2011-09-21
公開日2012-02-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of alpha5beta1 integrin ectodomain: Atomic details of the fibronectin receptor
J.Cell Biol., 197, 2012
3VI3
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BU of 3vi3 by Molmil
Crystal structure of alpha5beta1 integrin headpiece (ligand-free form)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Nagae, M, Nogi, T, Takagi, J.
登録日2011-09-21
公開日2012-02-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of alpha5beta1 integrin ectodomain: Atomic details of the fibronectin receptor
J.Cell Biol., 197, 2012
8TTN
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BU of 8ttn by Molmil
PHF1-Phosphomimetic Tau Filaments (Full-length, Cofactor-Free 0N4R Tau S396E, S400E, T403E, S404E)
分子名称: Microtubule-associated protein tau
著者El Mammeri, N, Dregni, A.J, Duan, P, Hong, M.
登録日2023-08-14
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Structures of AT8 and PHF1 phosphomimetic tau: Insights into the posttranslational modification code of tau aggregation.
Proc.Natl.Acad.Sci.USA, 121, 2024
8TTL
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BU of 8ttl by Molmil
AT8-Phosphomimetic Tau Filaments (Full-length, Cofactor-Free 0N4R Tau S202E, T205E, S208E)
分子名称: Microtubule-associated protein tau
著者El Mammeri, N, Dregni, A.J, Duan, P, Hong, M.
登録日2023-08-14
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structures of AT8 and PHF1 phosphomimetic tau: Insights into the posttranslational modification code of tau aggregation.
Proc.Natl.Acad.Sci.USA, 121, 2024
8UKV
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BU of 8ukv by Molmil
Crystal structure of nanobody/VHH domain of 34E5 in complex with the extracellular region of the epidermal growth factor variant III (EGFRvIII)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
著者Stayrook, S.E, Ferguson, K.M, Bagchi, A.
登録日2023-10-15
公開日2024-06-19
最終更新日2024-07-03
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Structural insights into the role and targeting of EGFRvIII.
Structure, 2024
1DKK
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BOBWHITE QUAIL LYSOZYME WITH NITRATE
分子名称: LYSOZYME, NITRATE ION
著者Jeffrey, P.D, Sheriff, S.
登録日1996-01-10
公開日1996-07-11
最終更新日2018-04-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Refined structures of bobwhite quail lysozyme uncomplexed and complexed with the HyHEL-5 Fab fragment.
Proteins, 26, 1996
1DKJ
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BOBWHITE QUAIL LYSOZYME
分子名称: LYSOZYME
著者Jeffrey, P.D, Sheriff, S.
登録日1996-01-10
公開日1996-07-11
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Refined structures of bobwhite quail lysozyme uncomplexed and complexed with the HyHEL-5 Fab fragment.
Proteins, 26, 1996
2LHV
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BU of 2lhv by Molmil
Mucin sequence based on MUC2 Mucin glycoprotein tandem repeat
分子名称: MUC2 Mucin Domain Peptide
著者Borgert, A, Heimburg-Molinaro, J, Lasanajak, Y, Ju, T, Liu, M, Thompson, P, Ragupathi, G, Barany, G, Cummings, R, Smith, D, Live, D.
登録日2011-08-18
公開日2012-04-04
最終更新日2012-06-27
実験手法SOLUTION NMR
主引用文献Deciphering structural elements of mucin glycoprotein recognition.
Acs Chem.Biol., 7, 2012
1JYI
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CONCANAVALIN A/12-MER PEPTIDE COMPLEX
分子名称: 12-mer peptide, CALCIUM ION, Concanavalin-Br, ...
著者Jain, D, Kaur, K.J, Sundaravadivel, B, Salunke, D.M.
登録日2001-09-12
公開日2002-09-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural and Functional Consequences of Peptide-carbohydrate Mimicry. Crystal Structure of a Carbohydrate-mimicking Peptide Bound to Concanavalin A.
J.Biol.Chem., 275, 2000

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