4ZH9
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5ANK
| Crystal structure of CDK2 in complex with 2,4,6-trioxo-1-phenyl- hexahydropyrimidine-5-carboxamide processed with the CrystalDirect automated mounting and cryo-cooling technology | 分子名称: | 2,4,6-TRIOXO-1-PHENYL-HEXAHYDROPYRIMIDINE-5-CARBOXAMIDE, CYCLIN-DEPENDENT KINASE 2 | 著者 | Zander, U, Hoffmann, G, Mathieu, M, Marquette, J.-P, Cornaciu, I, Cipriani, F, Marquez, J.A. | 登録日 | 2015-09-07 | 公開日 | 2016-04-13 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Automated Harvesting and Processing of Protein Crystals Through Laser Photoablation. Acta Crystallogr.,Sect.D, 72, 2016
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4RJ3
| CDK2 with EGFR inhibitor compound 8 | 分子名称: | 1-cyclopentyl-N-[2-(4-methoxypiperidin-1-yl)pyrimidin-4-yl]-1H-pyrrolo[3,2-c]pyridin-6-amine, ACETATE ION, Cyclin-dependent kinase 2 | 著者 | Eigenbrot, C, Yin, J. | 登録日 | 2014-10-08 | 公開日 | 2014-11-26 | 最終更新日 | 2015-01-14 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Discovery of Selective and Noncovalent Diaminopyrimidine-Based Inhibitors of Epidermal Growth Factor Receptor Containing the T790M Resistance Mutation. J.Med.Chem., 57, 2014
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5YV9
| Structure of CaMKK2 in complex with CKI-009 | 分子名称: | 5-chloro-2-methoxy-4[(1Z)-3-(4-methoxyphenyl)-3-oxoprop-1-en-1-yl]aminobenzoic acid, CHLORIDE ION, Calcium/calmodulin-dependent protein kinase kinase 2, ... | 著者 | Niwa, H, Handa, N, Yokoyama, S. | 登録日 | 2017-11-24 | 公開日 | 2018-12-05 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | Protein ligand interaction analysis against new CaMKK2 inhibitors by use of X-ray crystallography and the fragment molecular orbital (FMO) method. J.Mol.Graph.Model., 99, 2020
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4ZHD
| Siderocalin-mediated recognition and cellular uptake of actinides | 分子名称: | GLYCEROL, Neutrophil gelatinase-associated lipocalin, PLUTONIUM ION, ... | 著者 | Allred, B.E, Rupert, P.B, Gauny, S.S, An, D.D, Ralston, C.Y, Sturzbecher-Hoehne, M, Strong, R.K, Abergel, R.J. | 登録日 | 2015-04-24 | 公開日 | 2015-08-05 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides. Proc.Natl.Acad.Sci.USA, 112, 2015
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5AZR
| Crystal structure of aqua-cobalt(III) tetradehydrocorrin in the heme pocket of horse heart myoglobin | 分子名称: | (1R,19R) cobalt tetradehydrocorrin, (1S,19S) cobalt tetradehydrocorrin, GLYCEROL, ... | 著者 | Mizohata, E, Morita, Y, Oohora, K, Inoue, T, Hayashi, T. | 登録日 | 2015-10-21 | 公開日 | 2016-01-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Crystal Structures and Coordination Behavior of Aqua- and Cyano-Co(III) Tetradehydrocorrins in the Heme Pocket of Myoglobin Inorg.Chem., 55, 2016
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4ZHL
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4RAT
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6ROZ
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4ZES
| Blood dendritic cell antigen 2 (BDCA-2) complexed with methyl-mannoside | 分子名称: | C-type lectin domain family 4 member C, CALCIUM ION, MAGNESIUM ION, ... | 著者 | Jegouzo, S.A.F, Feinberg, H, Dungarwalla, T, Drickamer, K, Weis, W.I, Taylor, M.E. | 登録日 | 2015-04-20 | 公開日 | 2015-05-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | A Novel Mechanism for Binding of Galactose-terminated Glycans by the C-type Carbohydrate Recognition Domain in Blood Dendritic Cell Antigen 2. J.Biol.Chem., 290, 2015
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4RKF
| Drosophila melanogaster Rab3 bound to GMPPNP | 分子名称: | MAGNESIUM ION, PENTAETHYLENE GLYCOL, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Lardong, J.A, Driller, J.H, Depner, H, Weise, C, Petzoldt, A, Wahl, M.C, Sigrist, S.J, Loll, B. | 登録日 | 2014-10-13 | 公開日 | 2014-12-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structures of Drosophila melanogaster Rab2 and Rab3 bound to GMPPNP. Acta Crystallogr F Struct Biol Commun, 71, 2015
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6RP5
| Crystal structure of monocarboxylated hemoglobin from the sub-Antarctic fish Eleginops maclovinus | 分子名称: | CARBON MONOXIDE, DITHIONITE, Hemoglobin subunit alpha 1, ... | 著者 | Balasco, N, Vitagliano, L, Merlino, A, Verde, C, Mazzarella, L, Vergara, A. | 登録日 | 2019-05-13 | 公開日 | 2019-12-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | The unique structural features of carbonmonoxy hemoglobin from the sub-Antarctic fish Eleginops maclovinus. Sci Rep, 9, 2019
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6RQ4
| Inhibitor of ERK2 | 分子名称: | 6,6-dimethyl-2-[2-[(2-methylpyrazol-3-yl)amino]pyrimidin-4-yl]-5-(2-morpholin-4-ylethyl)thieno[2,3-c]pyrrol-4-one, Mitogen-activated protein kinase 1, SULFATE ION | 著者 | O'Reilly, M. | 登録日 | 2019-05-15 | 公開日 | 2019-12-04 | 最終更新日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Dual-Mechanism ERK1/2 Inhibitors Exploit a Distinct Binding Mode to Block Phosphorylation and Nuclear Accumulation of ERK1/2. Mol.Cancer Ther., 19, 2020
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6RQE
| CYP121 in complex with 3-acetylene dicyclotyrosine | 分子名称: | 3-acetylene dicyclotyrosine, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Poddar, H, Levy, C. | 登録日 | 2019-05-15 | 公開日 | 2020-04-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Structure-Activity Relationships ofcyclo(l-Tyrosyl-l-tyrosine) Derivatives Binding toMycobacterium tuberculosisCYP121: Iodinated Analogues Promote Shift to High-Spin Adduct. J.Med.Chem., 62, 2019
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6CH6
| Dehaloperoxidase B in complex with substrate 2,4-dimethoxyphenol | 分子名称: | 2,4-dimethoxyphenol, Dehaloperoxidase B, GLYCEROL, ... | 著者 | de Serrano, V.S, Carey, L.M, Ghiladi, R.A. | 登録日 | 2018-02-22 | 公開日 | 2019-01-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Peroxidase versus Peroxygenase Activity: Substrate Substituent Effects as Modulators of Enzyme Function in the Multifunctional Catalytic Globin Dehaloperoxidase. Biochemistry, 57, 2018
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5Z9J
| Identification of the functions of unusual cytochrome p450-like monooxygenases involved in microbial secondary metablism | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Putative P450-like enzyme, TRIS(HYDROXYETHYL)AMINOMETHANE | 著者 | Lu, M, Lin, L, Zhang, C, Chen, Y. | 登録日 | 2018-02-03 | 公開日 | 2019-02-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Riboflavin Is Directly Involved in the N-Dealkylation Catalyzed by Bacterial Cytochrome P450 Monooxygenases. Chembiochem, 2020
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4ROJ
| Crystal Structure of the VAV2 SH2 domain in complex with TXNIP phosphorylated peptide | 分子名称: | Guanine nucleotide exchange factor VAV2, Thioredoxin-interacting protein, UNKNOWN ATOM OR ION | 著者 | Liu, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2014-10-28 | 公開日 | 2014-12-10 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Crystal Structure of the VAV2 SH2 domain in complex with TXNIP phosphorylated peptide TO BE PUBLISHED
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5B1W
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8WDI
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4ZJ9
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4RLM
| Hen egg-white lysozyme solved from serial crystallography at a synchrotron source, data processed with CrystFEL | 分子名称: | Lysozyme C | 著者 | Botha, S, Nass, K, Barends, T, Kabsch, W, Latz, B, Dworkowski, F, Foucar, L, Panepucci, E, Wang, M, Shoeman, R, Schlichting, I, Doak, R.B. | 登録日 | 2014-10-17 | 公開日 | 2015-02-25 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Room-temperature serial crystallography at synchrotron X-ray sources using slowly flowing free-standing high-viscosity microstreams. Acta Crystallogr.,Sect.D, 71, 2015
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5B30
| H-Ras WT in complex with GppNHp (state 1) after structural transition by humidity control | 分子名称: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | 著者 | Kumasaka, T, Miyano, N, Baba, S, Matsumoto, S, Kataoka, T, Shima, F. | 登録日 | 2016-02-08 | 公開日 | 2016-06-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Molecular Mechanism for Conformational Dynamics of Ras-GTP Elucidated from In-Situ Structural Transition in Crystal Sci Rep, 6, 2016
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7VLJ
| Crystal structure of Entamoeba histolytica serine protease inhibitor, Histopin, in the cleaved conformation | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, POTASSIUM ION, ... | 著者 | Ali, M.F, Devi, S, Gourinath, S. | 登録日 | 2021-10-03 | 公開日 | 2021-11-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Crystal structure of Entamoeba histolytica serine protease inhibitor, Histopin, in the cleaved conformation To Be Published
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6RUG
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4ZHH
| Siderocalin-mediated recognition and cellular uptake of actinides | 分子名称: | CHLORIDE ION, GLYCEROL, N,N'-butane-1,4-diylbis[1-hydroxy-N-(3-{[(1-hydroxy-6-oxo-1,6-dihydropyridin-2-yl)carbonyl]amino}propyl)-6-oxo-1,6-dihydropyridine-2-carboxamide], ... | 著者 | Allred, B.E, Rupert, P.B, Gauny, S.S, An, D.D, Ralston, C.Y, Sturzbecher-Hoehne, M, Strong, R.K, Abergel, R.J. | 登録日 | 2015-04-24 | 公開日 | 2015-08-05 | 最終更新日 | 2015-09-02 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Siderocalin-mediated recognition, sensitization, and cellular uptake of actinides. Proc.Natl.Acad.Sci.USA, 112, 2015
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