6YPU
 
 | | Acinetobacter baumannii ribosome-amikacin complex - 30S subunit body | | 分子名称: | (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide, 16S ribosomal RNA, 30S ribosomal protein S11, ... | | 著者 | Nicholson, D, Edwards, T.A, O'Neill, A.J, Ranson, N.A. | | 登録日 | 2020-04-16 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of the 70S Ribosome from the Human Pathogen Acinetobacter baumannii in Complex with Clinically Relevant Antibiotics.
Structure, 28, 2020
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1WZZ
 | | Structure of endo-beta-1,4-glucanase CMCax from Acetobacter xylinum | | 分子名称: | Probable endoglucanase, SULFATE ION | | 著者 | Yasutake, Y, Kawano, S, Tajima, K, Yao, M, Satoh, Y, Munekata, M, Tanaka, I, Structural Genomics Consortium (SGC) | | 登録日 | 2005-03-10 | | 公開日 | 2006-03-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural characterization of the Acetobacter xylinum endo-beta-1,4-glucanase CMCax required for cellulose biosynthesis.
Proteins, 64, 2006
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3KJT
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1FQA
 | | STRUCTURE OF MALTOTETRAITOL BOUND TO OPEN-FORM MALTODEXTRIN BINDING PROTEIN IN P2(1)CRYSTAL FORM | | 分子名称: | MALTODEXTRIN-BINDING PROTEIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-sorbitol | | 著者 | Duan, X, Hall, J.A, Nikaido, H, Quiocho, F.A. | | 登録日 | 2000-09-04 | | 公開日 | 2001-03-14 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structures of the maltodextrin/maltose-binding protein complexed with reduced oligosaccharides: flexibility of tertiary structure and ligand binding.
J.Mol.Biol., 306, 2001
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3A3C
 | | Crystal structure of TIM40/MIA40 fusing MBP, C296S and C298S mutant | | 分子名称: | Maltose-binding periplasmic protein, LINKER, Mitochondrial intermembrane space import and assembly protein 40, ... | | 著者 | Kawano, S, Naoe, M, Momose, T, Watanabe, N, Endo, T. | | 登録日 | 2009-06-11 | | 公開日 | 2009-08-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural basis of yeast Tim40/Mia40 as an oxidative translocator in the mitochondrial intermembrane space.
Proc.Natl.Acad.Sci.USA, 106, 2009
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1FQC
 | | CRYSTAL STRUCTURE OF MALTOTRIOTOL BOUND TO CLOSED-FORM MALTODEXTRIN BINDING PROTEIN | | 分子名称: | MALTODEXTRIN-BINDING PROTEIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-D-glucose | | 著者 | Duan, X, Hall, J.A, Nikaido, H, Quiocho, F.A. | | 登録日 | 2000-09-04 | | 公開日 | 2001-03-14 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structures of the maltodextrin/maltose-binding protein complexed with reduced oligosaccharides: flexibility of tertiary structure and ligand binding.
J.Mol.Biol., 306, 2001
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3L2J
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3BJI
 | | Structural Basis of Promiscuous Guanine Nucleotide Exchange by the T-Cell Essential Vav1 | | 分子名称: | Proto-oncogene vav, Ras-related C3 botulinum toxin substrate 1 precursor, ZINC ION | | 著者 | Chrencik, J.E, Brooun, A, Kuhn, P, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) | | 登録日 | 2007-12-04 | | 公開日 | 2008-07-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1.
J.Mol.Biol., 380, 2008
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6PFO
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3J9P
 | | Structure of the TRPA1 ion channel determined by electron cryo-microscopy | | 分子名称: | Maltose-binding periplasmic protein, Transient receptor potential cation channel subfamily A member 1 chimera | | 著者 | Paulsen, C.E, Armache, J.-P, Gao, Y, Cheng, Y, Julius, D. | | 登録日 | 2015-02-14 | | 公開日 | 2015-04-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.24 Å) | | 主引用文献 | Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Nature, 520, 2015
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6YSN
 | | Human TRPC5 in complex with Pico145 (HC-608) | | 分子名称: | 7-[(4-chlorophenyl)methyl]-3-methyl-1-(3-oxidanylpropyl)-8-[3-(trifluoromethyloxy)phenoxy]purine-2,6-dione, Maltose/maltodextrin-binding periplasmic protein,Short transient receptor potential channel 5 | | 著者 | Wright, D.J, Johnson, R.M, Muench, S.P, Bon, R.S. | | 登録日 | 2020-04-22 | | 公開日 | 2020-12-02 | | 最終更新日 | 2020-12-09 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site.
Commun Biol, 3, 2020
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6PMI
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6ZHO
 | | Crystal structure of a CGRP receptor ectodomain heterodimer with bound high affinity inhibitor | | 分子名称: | Maltose/maltodextrin-binding periplasmic protein,Receptor activity-modifying protein 1,Calcitonin gene-related peptide type 1 receptor, TETRAETHYLENE GLYCOL, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | | 著者 | Southall, S.M. | | 登録日 | 2020-06-23 | | 公開日 | 2020-07-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-Based Drug Discovery ofN-((R)-3-(7-Methyl-1H-indazol-5-yl)-1-oxo-1-(((S)-1-oxo-3-(piperidin-4-yl)-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl)amino)propan-2-yl)-2'-oxo-1',2'-dihydrospiro[piperidine-4,4'-pyrido[2,3-d][1,3]oxazine]-1-carboxamide (HTL22562): A Calcitonin Gene-Related Peptide Receptor Antagonist for Acute Treatment of Migraine.
J.Med.Chem., 63, 2020
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6ZL6
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6ZLA
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6ZLK
 | | Equilibrium Structure of UDP-Glucuronic acid 4-epimerase from Bacillus cereus in complex with UDP-Glucuronic acid/UDP-Galacturonic acid and NAD | | 分子名称: | (2S,3R,4S,5R,6R)-6-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-oxane-2-carboxylic acid, Epimerase domain-containing protein, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | 著者 | Iacovino, L.G, Mattevi, A. | | 登録日 | 2020-06-30 | | 公開日 | 2020-07-29 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystallographic snapshots of UDP-glucuronic acid 4-epimerase ligand binding, rotation, and reduction.
J.Biol.Chem., 295, 2020
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1ZKB
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6QF7
 | | Crystal structures of the recombinant beta-Factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Coagulation factor XII, ... | | 著者 | Pathak, M, Mannal, R, Li, C, Bubacarr, G.K, Badraldin, K.H, Belviso, B.D, Camila, R.B, Dreveny, I, Fischer, P.M, Dekker, L.V, Oliva, M.L.V, Emsley, J. | | 登録日 | 2019-01-09 | | 公開日 | 2019-06-05 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (4 Å) | | 主引用文献 | Crystal structures of the recombinant beta-factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics.
Acta Crystallogr D Struct Biol, 75, 2019
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6Q62
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1ZN9
 | | Human Adenine Phosphoribosyltransferase in Apo and AMP Complexed Forms | | 分子名称: | ADENOSINE MONOPHOSPHATE, Adenine phosphoribosyltransferase | | 著者 | Iulek, J, Silva, M, Tomich, C.H.T.P, Thiemann, O.H. | | 登録日 | 2005-05-11 | | 公開日 | 2006-04-25 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural Complexes of Human Adenine Phosphoribosyltransferase Reveal Novel Features of the APRT Catalytic Mechanism
J.Biomol.Struct.Dyn., 25, 2008
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3KY9
 | | Autoinhibited Vav1 | | 分子名称: | Proto-oncogene vav, ZINC ION | | 著者 | Tomchick, D.R, Rosen, M.K, Machius, M, Yu, B. | | 登録日 | 2009-12-04 | | 公開日 | 2010-02-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.731 Å) | | 主引用文献 | Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1
Cell(Cambridge,Mass.), 140, 2010
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1FYC
 | | INNER LIPOYL DOMAIN FROM HUMAN PYRUVATE DEHYDROGENASE (PDH) COMPLEX, NMR, 1 STRUCTURE | | 分子名称: | DIHYDROLIPOAMIDE ACETYLTRANSFERASE (E2P) | | 著者 | Howard, M.J, Fuller, C, Broadhurst, R.W, Quinn, J, Yeaman, S.J, Perham, R.N. | | 登録日 | 1997-02-21 | | 公開日 | 1997-09-04 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Three-dimensional structure of the major autoantigen in primary biliary cirrhosis.
Gastroenterology, 115, 1998
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3AQS
 | | Crystal structure of RolR (NCGL1110) without ligand | | 分子名称: | Bacterial regulatory proteins, tetR family | | 著者 | Li, D.F, Zhang, N, Hou, Y.J, Liu, S.J, Wang, D.C. | | 登録日 | 2010-11-18 | | 公開日 | 2011-07-06 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Crystal structures of the transcriptional repressor RolR reveals a novel recognition mechanism between inducer and regulator.
Plos One, 6, 2011
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1GD6
 | | STRUCTURE OF THE BOMBYX MORI LYSOZYME | | 分子名称: | LYSOZYME | | 著者 | Matsuura, A, Aizawa, T, Yao, M, Kawano, K, Tanaka, I, Nitta, K. | | 登録日 | 2000-09-19 | | 公開日 | 2001-03-21 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural analysis of an insect lysozyme exhibiting catalytic efficiency at low temperatures.
Biochemistry, 41, 2002
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6QGD
 | | Structure of human Mcl-1 in complex with thienopyrimidine inhibitor | | 分子名称: | 2-[(6-ethyl-5-phenyl-thieno[2,3-d]pyrimidin-4-yl)amino]-3-oxidanyl-propanoic acid, Maltose-binding periplasmic protein,Induced myeloid leukemia cell differentiation protein Mcl-1, SODIUM ION, ... | | 著者 | Dokurno, P, Murray, J, Davidson, J, Chen, I, Davis, B, Graham, C.J, Harris, R, Jordan, A.M, Matassova, N, Pedder, C, Ray, S, Roughley, S, Smith, J, Walmsley, C, Wang, Y, Whitehead, N, Williamson, D.S, Casara, P, Le Diguarher, T, Hickman, J, Stark, J, Kotschy, A, Geneste, O, Hubbard, R.E. | | 登録日 | 2019-01-11 | | 公開日 | 2019-06-12 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Establishing Drug Discovery and Identification of Hit Series for the Anti-apoptotic Proteins, Bcl-2 and Mcl-1.
Acs Omega, 4, 2019
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