PDB: 2832 件ウェブページステータス検索Chemie searchBIRD

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4WSN	Crystal structure of the COP9 signalosome, a P1 crystal form 分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... 著者 Bunker, R.D, Lingaraju, G.M, Thoma, N.H. 登録日 2014-10-28 公開日 2015-12-23 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (5.5 Å) 主引用文献 Cullin-RING ubiquitin E3 ligase regulation by the COP9 signalosome. Nature, 531, 2016
1U6G	Crystal Structure of The Cand1-Cul1-Roc1 Complex 分子名称: Cullin homolog 1, RING-box protein 1, TIP120 protein, ... 著者 Goldenberg, S.J, Shumway, S.D, Cascio, T.C, Garbutt, K.C, Liu, J, Xiong, Y, Zheng, N. 登録日 2004-07-29 公開日 2004-12-14 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the multisubunit cullin-dependent ubiquitin ligases Cell(Cambridge,Mass.), 119, 2004
6SRI	Structure of the Fanconi anaemia core complex 分子名称: Fanconi anaemia protein FANCL, Unassigned secondary structure elements (base region, proposed FANCC-FANC-E-FANCF), ... 著者 Shakeel, S, Rajendra, E, Alcon, P, He, S, Scheres, S.H.W, Passmore, L.A. 登録日 2019-09-05 公開日 2019-11-06 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structure of the Fanconi anaemia monoubiquitin ligase complex. Nature, 575, 2019
6S53	Crystal structure of TRIM21 RING domain in complex with an isopeptide-linked Ube2N~ubiquitin conjugate 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, ... 著者 Kiss, L, Boland, A, Neuhaus, D, James, L.C. 登録日 2019-06-30 公開日 2019-09-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases. Nat Commun, 10, 2019
1Z5S	Crystal structure of a complex between UBC9, SUMO-1, RANGAP1 and NUP358/RANBP2 分子名称: Ran GTPase-activating protein 1, Ran-binding protein 2, Ubiquitin-conjugating enzyme E2 I, ... 著者 Reverter, D, Lima, C.D. 登録日 2005-03-19 公開日 2005-06-07 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Insights into E3 ligase activity revealed by a SUMO-RanGAP1-Ubc9-Nup358 complex. Nature, 435, 2005
8JRN	Structure of E6AP-E6 complex in Att1 state 分子名称: Protein E6, Ubiquitin-protein ligase E3A, ZINC ION 著者 Wang, Z, Yu, X. 登録日 2023-06-17 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural insights into the functional mechanism of the ubiquitin ligase E6AP. Nat Commun, 15, 2024
8JRQ	Structure of E6AP-E6 complex in Det1 state 分子名称: Protein E6, Ubiquitin-protein ligase E3A, ZINC ION 著者 Wang, Z, Yu, X. 登録日 2023-06-17 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (4.15 Å) 主引用文献 Structural insights into the functional mechanism of the ubiquitin ligase E6AP. Nat Commun, 15, 2024
8JRO	Structure of E6AP-E6 complex in Att2 state 分子名称: Protein E6, Ubiquitin-protein ligase E3A, ZINC ION 著者 Wang, Z, Yu, X. 登録日 2023-06-17 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.01 Å) 主引用文献 Structural insights into the functional mechanism of the ubiquitin ligase E6AP. Nat Commun, 15, 2024
4PW7	structure of UHRF2-SRA in complex with a 5mC-containing DNA 分子名称: 5mC-containing DNA1, 5mC-containing DNA2, E3 ubiquitin-protein ligase UHRF2 著者 ZHou, T, Xiong, J, Wang, M, Yang, N, Wong, J, Zhu, B, Xu, R.M. 登録日 2014-03-19 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2. Mol.Cell, 54, 2014
6SRS	Structure of the Fanconi anaemia core subcomplex 分子名称: Fanconi anaemia protein FANCL, Unassigned secondary structure elements (central region, proposed FANCB-FAAP100), ... 著者 Shakeel, S, Rajendra, E, Alcon, P, He, S, Scheres, S.H.W, Passmore, L.A. 登録日 2019-09-05 公開日 2019-11-06 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Structure of the Fanconi anaemia monoubiquitin ligase complex. Nature, 575, 2019
4PW6	structure of UHRF2-SRA in complex with a 5hmC-containing DNA, complex II 分子名称: 5hmC-containing DNA1, 5hmC-containing DNA2, E3 ubiquitin-protein ligase UHRF2 著者 Zhou, T, Xiong, J, Wang, M, Yang, N, Wong, J, Zhu, B, Xu, R.M. 登録日 2014-03-18 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.789 Å) 主引用文献 Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2. Mol.Cell, 54, 2014
4PW5	structure of UHRF2-SRA in complex with a 5hmC-containing DNA, complex I 分子名称: 5hmC-containing DNA1, 5hmC-containing DNA2, E3 ubiquitin-protein ligase UHRF2 著者 ZHou, T, Xiong, J, Wang, M, Yang, N, Wong, J, Zhu, B, Xu, R.M. 登録日 2014-03-18 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.204 Å) 主引用文献 Structural Basis for Hydroxymethylcytosine Recognition by the SRA Domain of UHRF2. Mol.Cell, 54, 2014
6QC0	PCNA complex with Cdt2 C-terminal PIP-box peptide 分子名称: Denticleless protein homolog, Proliferating cell nuclear antigen 著者 Perrakis, A.P, von Castelmur, E. 登録日 2018-12-25 公開日 2019-01-23 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Direct binding of Cdt2 to PCNA is important for targeting the CRL4Cdt2E3 ligase activity to Cdt1. Life Sci Alliance, 1, 2018
4ZTD	Crystal Structure of Human PCNA in complex with a TRAIP peptide 分子名称: ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen 著者 Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A. 登録日 2015-05-14 公開日 2015-12-16 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress. J.Cell Biol., 212, 2016
7OIK	Mouse RNF213:UBE2L3 transthiolation intermediate, chemically stabilized 分子名称: ADENOSINE-5'-TRIPHOSPHATE, E3 ubiquitin-protein ligase RNF213, MAGNESIUM ION, ... 著者 Grabarczyk, D, Ahel, J, Clausen, T. 登録日 2021-05-11 公開日 2022-06-01 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 E3 ubiquitin ligase RNF213 employs a non-canonical zinc finger active site and is allosterically regulated by ATP To Be Published
1V66	Solution structure of human p53 binding domain of PIAS-1 分子名称: Protein inhibitor of activated STAT protein 1 著者 Okubo, S, Hara, F, Tsuchida, Y, Shimotakahara, S, Suzuki, S, Hatanaka, H, Yokoyama, S, Tanaka, H, Yasuda, H, Shindo, H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2003-11-27 公開日 2004-12-07 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 NMR structure of the N-terminal domain of SUMO ligase PIAS1 and its interaction with tumor suppressor p53 and A/T-rich DNA oligomers J.Biol.Chem., 279, 2004
8G66	Structure with SJ3149 分子名称: (3S)-3-{5-[(1,2-benzoxazol-3-yl)amino]-1-oxo-1,3-dihydro-2H-isoindol-2-yl}piperidine-2,6-dione, Casein kinase I isoform alpha, DNA damage-binding protein 1, ... 著者 Miller, D.J, Young, S.M, Fischer, M. 登録日 2023-02-14 公開日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Structure of ternary complex with molecular glue targeting CK1A for degradation by the CRL4CRBN ubiquitin ligase To Be Published
3DB3	Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 in complex with trimethylated histone H3-K9 peptide 分子名称: E3 ubiquitin-protein ligase UHRF1, Trimethylated histone H3-K9 peptide 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2008-05-30 公開日 2008-09-16 最終更新日 2012-04-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein. J.Biol.Chem., 286, 2011
6JXU	SUMO1 bound to SLS4-SIM peptide from ICP0 分子名称: Small ubiquitin-related modifier, viral protein 著者 Hembram, D.S.S, Negi, H, Shet, D, Das, R. 登録日 2019-04-25 公開日 2020-02-05 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The Viral SUMO-Targeted Ubiquitin Ligase ICP0 is Phosphorylated and Activated by Host Kinase Chk2. J.Mol.Biol., 432, 2020
3DB4	Crystal structure of the tandem tudor domains of the E3 ubiquitin-protein ligase UHRF1 分子名称: E3 ubiquitin-protein ligase UHRF1, SULFATE ION 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Dong, A, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2008-05-30 公開日 2008-09-16 最終更新日 2012-04-18 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Recognition of multivalent histone states associated with heterochromatin by UHRF1 protein. J.Biol.Chem., 286, 2011
3GCB	GAL6 (YEAST BLEOMYCIN HYDROLASE) MUTANT C73A/DELTAK454 分子名称: GAL6, GLYCEROL, SULFATE ION 著者 Joshua-Tor, L, Zheng, W, Johnston, S.A. 登録日 1998-02-27 公開日 1998-10-21 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell(Cambridge,Mass.), 93, 1998
6N13	UbcH7-Ub Complex with R0RBR Parkin and phosphoubiquitin 分子名称: E3 ubiquitin-protein ligase parkin, Ubiquitin-conjugating enzyme E2 L3, ZINC ION, ... 著者 Condos, T.E.C, Dunkerley, K.M, Freeman, E.A, Barber, K.R, Aguirre, J.D, Chaugule, V.K, Xiao, Y, Konermann, L, Walden, H, Shaw, G.S. 登録日 2018-11-08 公開日 2018-11-28 最終更新日 2020-01-08 実験手法 SOLUTION NMR 主引用文献 Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation. EMBO J., 37, 2018
5M88	Spliceosome component 分子名称: Core 著者 Moura, T.R, Pena, V. 登録日 2016-10-28 公開日 2018-02-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors. Mol. Cell, 69, 2018
5M89	Spliceosome component 分子名称: Spliceosome WD40 Sc 著者 Moura, T.R, Pena, V. 登録日 2016-10-28 公開日 2018-03-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.605 Å) 主引用文献 Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors. Mol. Cell, 69, 2018
5M8C	Spliceosome component 分子名称: Pre-mRNA-processing factor 19 著者 Moura, T.R, Pena, V. 登録日 2016-10-28 公開日 2018-02-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors. Mol. Cell, 69, 2018

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