8P7U
 
 | | The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: A case study on Bacterial Phosphotriesterase Variants and complexes | | 分子名称: | 1-ethyl-1-methyl-cyclohexane, FORMIC ACID, GLYCEROL, ... | | 著者 | Dym, O, Aggarwal, N, Ashani, Y, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Sussman, J.L. | | 登録日 | 2023-05-31 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.
Acta Crystallogr D Struct Biol, 79, 2023
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8P7R
 | | The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: A case study on Bacterial Phosphotriesterase Variants and complexes | | 分子名称: | 1-ethyl-1-methyl-cyclohexane, FORMIC ACID, GLYCEROL, ... | | 著者 | Dym, O, Aggarwal, N, Ashani, Y, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Sussman, J.L. | | 登録日 | 2023-05-30 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.
Acta Crystallogr D Struct Biol, 79, 2023
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8P7T
 | | The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: A case study on Bacterial Phosphotriesterase Variants and complexes | | 分子名称: | 1-ethyl-1-methyl-cyclohexane, FORMIC ACID, GLYCEROL, ... | | 著者 | Dym, O, Aggarwal, N, Ashani, Y, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Sussman, J.L. | | 登録日 | 2023-05-31 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.
Acta Crystallogr D Struct Biol, 79, 2023
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8P7M
 | | The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: A case study on Bacterial Phosphotriesterase Variants and complexes | | 分子名称: | FORMIC ACID, GLYCEROL, METHYLPHOSPHONIC ACID ESTER GROUP, ... | | 著者 | Dym, O, Aggarwal, N, Ashani, Y, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Sussman, J.L. | | 登録日 | 2023-05-30 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.
Acta Crystallogr D Struct Biol, 79, 2023
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8P7H
 | | The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: A case study on Bacterial Phosphotriesterase Variants and complexes | | 分子名称: | 1,2-ETHANEDIOL, 2-methylidene-1,3-dioxane-4,4-diol, FORMIC ACID, ... | | 著者 | Dym, O, Aggarwal, N, Ashani, Y, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Sussman, J.L. | | 登録日 | 2023-05-30 | | 公開日 | 2023-10-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.774 Å) | | 主引用文献 | The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.
Acta Crystallogr D Struct Biol, 79, 2023
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8P7F
 | | The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: A case study on Bacterial Phosphotriesterase Variants and complexes | | 分子名称: | Parathion hydrolase, ZINC ION | | 著者 | Dym, O, Aggarwal, N, Ashani, Y, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Sussman, J.L. | | 登録日 | 2023-05-30 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.
Acta Crystallogr D Struct Biol, 79, 2023
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6BH7
 | | Phosphotriesterase variant R18+254S | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... | | 著者 | Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. | | 登録日 | 2017-10-30 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Phosphotriesterase variant R18+254S
To Be Published
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6BHK
 | | Phosphotriesterase variant R18deltaL7 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Phosphotriesterase, ZINC ION | | 著者 | Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. | | 登録日 | 2017-10-30 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Phosphotriesterase variant R18deltaL7
To Be Published
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8BRW
 | | Escherichia coli methionyl-tRNA synthetase mutant L13C,I297C | | 分子名称: | Methionine--tRNA ligase, ZINC ION | | 著者 | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | | 登録日 | 2022-11-24 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments.
Protein Sci., 32, 2023
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8BRX
 | | Escherichia coli methionyl-tRNA synthetase mutant L13C,I297C complexed with beta-3-methionine | | 分子名称: | (3R)-3-amino-5-(methylsulfanyl)pentanoic acid, CITRIC ACID, Methionine--tRNA ligase, ... | | 著者 | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | | 登録日 | 2022-11-24 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments.
Protein Sci., 32, 2023
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8BRV
 | | Escherichia coli methionyl-tRNA synthetase mutant L13M,I297C complexed with beta3-methionine. | | 分子名称: | (3R)-3-amino-5-(methylsulfanyl)pentanoic acid, CITRIC ACID, Methionine--tRNA ligase, ... | | 著者 | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | | 登録日 | 2022-11-24 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments.
Protein Sci., 32, 2023
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8BRU
 | | Escherichia coli methionyl-tRNA synthetase mutant L13M,I297C | | 分子名称: | CITRIC ACID, Methionine--tRNA ligase, ZINC ION | | 著者 | Schmitt, E, Mechulam, Y, Nigro, G, Opuu, V, Lazennec-Schurdevin, C, Simonson, T. | | 登録日 | 2022-11-24 | | 公開日 | 2023-08-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Redesigning methionyl-tRNA synthetase for beta-methionine activity with adaptive landscape flattening and experiments.
Protein Sci., 32, 2023
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6RXJ
 | | Crystal structure of CobB wt in complex with H4K16-Acetyl peptide | | 分子名称: | Histone H4, NAD-dependent protein deacylase, ZINC ION | | 著者 | Spinck, M, Gasper, R, Neumann, H. | | 登録日 | 2019-06-08 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Evolved, Selective Erasers of Distinct Lysine Acylations.
Angew.Chem.Int.Ed.Engl., 59, 2020
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8AIT
 | | Crystal structure of cutinase PbauzCut from Pseudomonas bauzanensis | | 分子名称: | Cutinase, SULFATE ION | | 著者 | Zahn, M, Allen, M.D, Pickford, A.R, McGeehan, J.E. | | 登録日 | 2022-07-27 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.24 Å) | | 主引用文献 | Concentration-Dependent Inhibition of Mesophilic PETases on Poly(ethylene terephthalate) Can Be Eliminated by Enzyme Engineering.
ChemSusChem, 16, 2023
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8PF0
 | | Diubiquitin-derived artificial binding protein (Affilin) variant Af1 specific to oncofetal fibronectin | | 分子名称: | Affilin variant Af1 (77405), COPPER (II) ION, IMIDAZOLE | | 著者 | Parthier, C, Katzschmann, A, Fiedler, E, Haupts, U, Reimann, A. | | 登録日 | 2023-06-15 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Ubiquitin-derived artificial binding proteins targeting oncofetal fibronectin reveal scaffold plasticity by beta-strand slippage
to be published
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8AIR
 | | Crystal structure of cutinase RgCutII from Rhizobacter gummiphilus | | 分子名称: | ACETATE ION, RgCutII | | 著者 | Zahn, M, Allen, M.D, Pickford, A.R, McGeehan, J.E. | | 登録日 | 2022-07-27 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.08 Å) | | 主引用文献 | Concentration-Dependent Inhibition of Mesophilic PETases on Poly(ethylene terephthalate) Can Be Eliminated by Enzyme Engineering.
ChemSusChem, 16, 2023
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8PEQ
 | | Complex of diubiquitin-derived artificial binding protein (Affilin) variant Af2 with its target oncofetal fibronectin (fragment 7B8) | | 分子名称: | Affilin variant Af2, Fibronectin, SULFATE ION | | 著者 | Parthier, C, Katzschmann, A, Fiedler, E, Haupts, U, Reimann, A. | | 登録日 | 2023-06-14 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Ubiquitin-derived artificial binding proteins targeting oncofetal fibronectin reveal scaffold plasticity by beta-strand slippage
to be published
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6RXM
 | | Crystal structure of CobB Ac2 (A76G, I131C, V162G) in complex with H4K16-Acetyl peptide | | 分子名称: | Histone H4, NAD-dependent protein deacylase, ZINC ION | | 著者 | Spinck, M, Gasper, R, Neumann, H. | | 登録日 | 2019-06-08 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Evolved, Selective Erasers of Distinct Lysine Acylations.
Angew.Chem.Int.Ed.Engl., 59, 2020
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8P4G
 | | Crystal structure of a multicopper oxidase 3F3 variant from Pyrobaculum aerophilum | | 分子名称: | CHLORIDE ION, COPPER (II) ION, Multicopper oxidase | | 著者 | Borges, P.T, Brissos, V, Frazao, C, Martins, L.O. | | 登録日 | 2023-05-21 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | | 主引用文献 | Flexible active-site loops fine-tune substrate specificity of hyperthermophilic metallo-oxidases.
J.Biol.Inorg.Chem., 29, 2024
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7UJJ
 | | Stx2a and DARPin complex | | 分子名称: | 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, DARPin, ... | | 著者 | Jiang, M, Zhang, J. | | 登録日 | 2022-03-30 | | 公開日 | 2023-04-12 | | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | | 主引用文献 | A Multi-Specific DARPin Potently Neutralizes Shiga Toxin 2 via Simultaneous Modulation of Both Toxin Subunits.
Bioengineering (Basel), 9, 2022
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8P7K
 | | The impact of molecular variants, crystallization conditions and space group on structure-ligand complexes: A case study on Bacterial Phosphotriesterase Variants and complexes | | 分子名称: | (2~{R})-2-methylpentanedioic acid, FORMIC ACID, Parathion hydrolase, ... | | 著者 | Dym, O, Aggawal, N, Ashani, Y, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Sussman, J.L. | | 登録日 | 2023-05-30 | | 公開日 | 2023-06-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.929 Å) | | 主引用文献 | The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase.
Acta Crystallogr D Struct Biol, 79, 2023
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7TPS
 | | Crystal structure of ALPN-202 (engineered CD80 vIgD) in complex with PD-L1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Demonte, D.W, Maurer, M.F, Akutsu, M, Kimbung, Y.R, Logan, D.T, Walse, B. | | 登録日 | 2022-01-26 | | 公開日 | 2022-03-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | The engineered CD80 variant fusion therapeutic davoceticept combines checkpoint antagonism with conditional CD28 costimulation for anti-tumor immunity.
Nat Commun, 13, 2022
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7VCM
 | | crystal structure of GINKO1 | | 分子名称: | Green fluorescent protein,Potassium binding protein Kbp,Green fluorescent protein, POTASSIUM ION | | 著者 | Wen, Y, Campbell, R.E, Lemieux, M.J. | | 登録日 | 2021-09-03 | | 公開日 | 2022-07-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | A sensitive and specific genetically-encoded potassium ion biosensor for in vivo applications across the tree of life.
Plos Biol., 20, 2022
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6BHL
 | | Phosphotriesterase variant S5deltaL7 | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Phosphotriesterase, ... | | 著者 | Miton, C.M, Campbell, E.C, Jackson, C.J, Tokuriki, N. | | 登録日 | 2017-10-30 | | 公開日 | 2019-01-23 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Phosphotriesterase variant S5deltaL7
To Be Published
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8PN7
 | | Engineered glycolyl-CoA carboxylase (G20R variant) with bound CoA | | 分子名称: | 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Propionyl-CoA carboxylase alpha subunit, ... | | 著者 | Zarzycki, J, Marchal, D.G, Schulz, L, Prinz, S, Erb, T.J. | | 登録日 | 2023-06-30 | | 公開日 | 2023-11-29 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (2.03 Å) | | 主引用文献 | Machine Learning-Supported Enzyme Engineering toward Improved CO 2 -Fixation of Glycolyl-CoA Carboxylase.
Acs Synth Biol, 12, 2023
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