2QWN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qwn by Molmil](/molmil-images/mine/2qwn) | Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-386aa)R171C and bovine Auxilin (810-910aa)D876C in the ADP*Pi state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Heat shock cognate 71 kDa protein, MAGNESIUM ION, ... | 著者 | Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R. | 登録日 | 2007-08-10 | 公開日 | 2007-12-18 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of J cochaperone binding and regulation of Hsp70. Mol.Cell, 28, 2007
|
|
2QWR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qwr by Molmil](/molmil-images/mine/2qwr) | Crystal structure of disulfide-bond-crosslinked complex of bovine hsc70 (1-394aa)R171C and bovine Auxilin (810-910aa)D876C in the AMPPNP intact form | 分子名称: | ACETIC ACID, GLYCEROL, Heat shock cognate 71 kDa protein, ... | 著者 | Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R. | 登録日 | 2007-08-10 | 公開日 | 2007-12-18 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Structural basis of J cochaperone binding and regulation of Hsp70. Mol.Cell, 28, 2007
|
|
2R1X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2r1x by Molmil](/molmil-images/mine/2r1x) | Crystal structure of S25-2 Fab in complex with Kdo analogues | 分子名称: | 2,6-anhydro-3,5-dideoxy-D-ribo-oct-2-enonic acid-(4-8)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, Fab, antibody fragment (IgG1k), ... | 著者 | Brooks, C.L, Evans, S.V. | 登録日 | 2007-08-23 | 公開日 | 2008-12-30 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes. J.Mol.Biol., 377, 2008
|
|
2QST
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qst by Molmil](/molmil-images/mine/2qst) | |
2QT5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qt5 by Molmil](/molmil-images/mine/2qt5) | Crystal Structure of GRIP1 PDZ12 in Complex with the Fras1 Peptide | 分子名称: | (ASN)(ASN)(LEU)(GLN)(ASP)(GLY)(THR)(GLU)(VAL), 1,2-ETHANEDIOL, ACETIC ACID, ... | 著者 | Long, J, Wei, Z, Feng, W, Zhao, Y, Zhang, M. | 登録日 | 2007-08-01 | 公開日 | 2008-06-03 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Supramodular nature of GRIP1 revealed by the structure of its PDZ12 tandem in complex with the carboxyl tail of Fras1. J.Mol.Biol., 375, 2008
|
|
2QKF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qkf by Molmil](/molmil-images/mine/2qkf) | Crystal structure of 3-deoxy-d-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis | 分子名称: | 3-deoxy-D-manno-octulosonic acid 8- phosphate synthetase, CHLORIDE ION, GLYCEROL, ... | 著者 | Cochrane, F.C, Patchett, M.L, Jameson, G.B, Parker, E.J. | 登録日 | 2007-07-11 | 公開日 | 2008-07-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Re-Establishing a Metal-Binding Scaffold with Full Activity in the Metal-Independent Kdo8P Synthase from Neisseria Meningitidis To be Published
|
|
2R1W
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2r1w by Molmil](/molmil-images/mine/2r1w) | Crystal structure of S25-2 Fab in complex with Kdo analogues | 分子名称: | 3,4,5-trideoxy-alpha-D-erythro-oct-3-en-2-ulopyranosonic acid-(2-8)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, Fab, antibody fragment (IgG1k), ... | 著者 | Brooks, C.L, Evans, S.V. | 登録日 | 2007-08-23 | 公開日 | 2008-12-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes. J.Mol.Biol., 377, 2008
|
|
2QWM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qwm by Molmil](/molmil-images/mine/2qwm) | Crystal structure of bovine hsc70 (1-394aa)in the ADP*Vi state | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Heat shock cognate 71 kDa protein, ... | 著者 | Jiang, J, Maes, E.G, Wang, L, Taylor, A.B, Hinck, A.P, Lafer, E.M, Sousa, R. | 登録日 | 2007-08-10 | 公開日 | 2007-12-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Structural basis of J cochaperone binding and regulation of Hsp70. Mol.Cell, 28, 2007
|
|
2QXZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2qxz by Molmil](/molmil-images/mine/2qxz) | pectate lyase R236F from Xanthomonas campestris | 分子名称: | PHOSPHATE ION, pectate lyase II | 著者 | Garron, M.L, Shaya, D. | 登録日 | 2007-08-13 | 公開日 | 2008-03-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Improvement of the thermostability and activity of a pectate lyase by single amino acid substitutions, using a strategy based on melting-temperature-guided sequence alignment. Appl.Environ.Microbiol., 74, 2008
|
|
2R5B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2r5b by Molmil](/molmil-images/mine/2r5b) | Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7 | 分子名称: | HIV entry inhibitor PIE7, SULFATE ION, gp41 N-peptide | 著者 | VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S. | 登録日 | 2007-09-03 | 公開日 | 2007-10-02 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Potent D-peptide inhibitors of HIV-1 entry Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2R5D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2r5d by Molmil](/molmil-images/mine/2r5d) | Structure of the gp41 N-trimer in complex with the HIV entry inhibitor PIE7 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, HIV entry inhibitor PIE7, ... | 著者 | VanDemark, A.P, Welch, B, Heroux, A, Hill, C.P, Kay, M.S. | 登録日 | 2007-09-03 | 公開日 | 2007-10-02 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Potent D-peptide inhibitors of HIV-1 entry Proc.Natl.Acad.Sci.Usa, 104, 2007
|
|
2R8T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2r8t by Molmil](/molmil-images/mine/2r8t) | Crystal structure of the fructose 1,6-bisphosphatase GlpX from E.coli in the complex with fructose 1,6-bisphosphate | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase class II glpX, UNKNOWN ATOM OR ION | 著者 | Lunin, V.V, Skarina, T, Brown, G, Yakunin, A, Edwards, A.M, Savchenko, A. | 登録日 | 2007-09-11 | 公開日 | 2008-08-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the fructose 1,6-bisphosphatase GlpX
from E.coli in the complex with fructose 1,6-bisphosphate To be Published
|
|
2JIH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2jih by Molmil](/molmil-images/mine/2jih) | Crystal Structure of Human ADAMTS-1 catalytic Domain and Cysteine- Rich Domain (complex-form) | 分子名称: | (2S,3R)-N~4~-[(1S)-2,2-dimethyl-1-(methylcarbamoyl)propyl]-N~1~,2-dihydroxy-3-(2-methylpropyl)butanediamide, ADAMTS-1, CADMIUM ION, ... | 著者 | Gerhardt, S, Hassall, G, Hawtin, P, McCall, E, Flavell, L, Minshull, C, Hargreaves, D, Ting, A, Pauptit, R.A, Parker, A.E, Abbott, W.M. | 登録日 | 2007-06-28 | 公開日 | 2008-01-15 | 最終更新日 | 2019-04-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures of human ADAMTS-1 reveal a conserved catalytic domain and a disintegrin-like domain with a fold homologous to cysteine-rich domains. J. Mol. Biol., 373, 2007
|
|
2LKB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2lkb by Molmil](/molmil-images/mine/2lkb) | Evolutionary diversification of Mesobuthus alpha-scorpion toxins affecting sodium channels | 分子名称: | Neurotoxin MeuNaTx-5 | 著者 | Zhu, S, Peigneur, S, Gao, B, Lu, X, Cao, C, Tytgat, J. | 登録日 | 2011-10-09 | 公開日 | 2011-11-02 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Evolutionary diversification of Mesobuthus {alpha}-scorpion toxins affecting sodium channels Mol.Cell Proteomics, 2011
|
|
5KZ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kz7 by Molmil](/molmil-images/mine/5kz7) | Mark2 complex with 7-[(1S)-1-(4-fluorophenyl)ethyl]-5,5-dimethyl-2-(3-pyridylamino)pyrrolo[2,3-d]pyrimidin-6-one | 分子名称: | 7-[(1~{S})-1-(4-fluorophenyl)ethyl]-5,5-dimethyl-2-(pyridin-3-ylamino)pyrrolo[2,3-d]pyrimidin-6-one, Serine/threonine-protein kinase MARK2 | 著者 | Su, H.P, Munshi, S.K. | 登録日 | 2016-07-23 | 公開日 | 2017-05-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
|
|
5KVK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5kvk by Molmil](/molmil-images/mine/5kvk) | Crystal structure of the Competence-Damaged Protein (CinA) Superfamily Protein KP700603 from Klebsiella pneumoniae 700603 | 分子名称: | Protein KP700603 | 著者 | Stogios, P.J, Wawrzak, Z, Evdokimova, E, Di Leo, R, Grimshaw, S, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2016-07-14 | 公開日 | 2016-08-03 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | To be published To Be Published
|
|
7MLC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mlc by Molmil](/molmil-images/mine/7mlc) | PYL10 bound to the ABA pan-antagonist 4a | 分子名称: | 1-{2-[3,5-dicyclopropyl-4-(4-{[(quinoxaline-2-carbonyl)amino]methyl}-1H-1,2,3-triazol-1-yl)phenyl]acetamido}cyclohexane-1-carboxylic acid, Abscisic acid receptor PYL10, GLYCEROL | 著者 | Peterson, F.C, Vaidya, A.S, Volkman, B.F, Cutler, S.R. | 登録日 | 2021-04-28 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7OR3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7or3 by Molmil](/molmil-images/mine/7or3) | Ternary complex of 14-3-3 sigma, NotchpS1917 phosphopeptide, and WQ136 | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Centorrino, F, Wu, Q, Ottmann, C. | 登録日 | 2021-06-04 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A crystallography-based study of fragment extensions
into the 14-3-3 binding groove To Be Published
|
|
5L4R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5l4r by Molmil](/molmil-images/mine/5l4r) | X-ray structure of the adduct between thaumatin and cisplatin | 分子名称: | Cisplatin, GLYCEROL, L(+)-TARTARIC ACID, ... | 著者 | Russo Krauss, I, Ferraro, G, Merlino, A. | 登録日 | 2016-05-26 | 公開日 | 2016-12-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Cisplatin-Protein Interactions: Unexpected Drug Binding to N-Terminal Amine and Lysine Side Chains. Inorg.Chem., 55, 2016
|
|
7ORS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ors by Molmil](/molmil-images/mine/7ors) | Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ147 | 分子名称: | (4~{S})-~{N}-[(5-carbamimidoyl-3-phenyl-thiophen-2-yl)methyl]oxepane-4-carboxamide, 14-3-3 protein sigma, CHLORIDE ION, ... | 著者 | Centorrino, F, Wu, Q, Ottmann, C. | 登録日 | 2021-06-06 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A crystallography-based study of fragment extensions
into the 14-3-3 binding groove To Be Published
|
|
7ORG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7org by Molmil](/molmil-images/mine/7org) | Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ162 | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, Cyclin-dependent kinase inhibitor 1B, ... | 著者 | Centorrino, F, Wu, Q, Ottmann, C. | 登録日 | 2021-06-05 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A crystallography-based study of fragment extensions
into the 14-3-3 binding groove To Be Published
|
|
7MLD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7mld by Molmil](/molmil-images/mine/7mld) | PYL10 bound to the ABA pan-antagonist antabactin | 分子名称: | Abscisic acid receptor PYL10, CITRIC ACID, antabactin | 著者 | Peterson, F.C, Vaidya, A.S, Volkman, B.F, Cutler, S.R. | 登録日 | 2021-04-28 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Click-to-lead design of a picomolar ABA receptor antagonist with potent activity in vivo. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
7OR8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7or8 by Molmil](/molmil-images/mine/7or8) | Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ136 | 分子名称: | 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... | 著者 | Centorrino, F, Wu, Q, Ottmann, C. | 登録日 | 2021-06-04 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A crystallography-based study of fragment extensions
into the 14-3-3 binding groove To Be Published
|
|
7ORT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7ort by Molmil](/molmil-images/mine/7ort) | Ternary complex of 14-3-3 sigma, p27pT198 phosphopeptide, and WQ176 | 分子名称: | 14-3-3 protein sigma, CHLORIDE ION, Cyclin-dependent kinase inhibitor 1B, ... | 著者 | Centorrino, F, Wu, Q, Ottmann, C. | 登録日 | 2021-06-06 | 公開日 | 2022-06-22 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.33 Å) | 主引用文献 | A crystallography-based study of fragment extensions
into the 14-3-3 binding groove To Be Published
|
|
7OQW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7oqw by Molmil](/molmil-images/mine/7oqw) | |