1EK2
| CRYSTAL STRUCTURE OF MURINE SOLUBLE EPOXIDE HYDROLASE COMPLEXED WITH CDU INHIBITOR | 分子名称: | EPOXIDE HYDROLASE, N-CYCLOHEXYL-N'-DECYLUREA | 著者 | Argiriadi, M.A, Morisseau, C, Goodrow, M.H, Dowdy, D.L, Hammock, B.D, Christianson, D.W. | 登録日 | 2000-03-06 | 公開日 | 2000-05-31 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activation. J.Biol.Chem., 275, 2000
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4BA7
| Crystal Structure of Ancestral Thioredoxin Relative to Last Bacteria Common Ancestor (LBCA) from the Precambrian Period | 分子名称: | 1,2-ETHANEDIOL, LBCA THIOREDOXIN | 著者 | Gavira, J.A, Ingles-Prieto, A, Ibarra-Molero, B, Sanchez-Ruiz, J.M. | 登録日 | 2012-09-12 | 公開日 | 2013-08-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Conservation of Protein Structure Over Four Billion Years Structure, 21, 2013
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7MNJ
| Crystal structure of the N-terminal domain of NUP358/RanBP2 (residues 145-673) | 分子名称: | E3 SUMO-protein ligase RanBP2 | 著者 | Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Patke, A, Dasso, M, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. | 登録日 | 2021-05-01 | 公開日 | 2022-06-15 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
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7MNR
| Crystal Structure of the ZnF3 of Nucleoporin NUP358/RanBP2 in complex with Ran-GDP | 分子名称: | E3 SUMO-protein ligase RanBP2, GTP-binding nuclear protein Ran, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Bley, C.J, Nie, S, Mobbs, G.W, Petrovic, S, Gres, A.T, Liu, X, Mukherjee, S, Harvey, S, Huber, F.M, Lin, D.H, Brown, B, Tang, A.W, Rundlet, E.J, Correia, A.R, Chen, S, Regmi, S.G, Stevens, T.A, Jette, C.A, Dasso, M, Patke, A, Palazzo, A.F, Kossiakoff, A.A, Hoelz, A. | 登録日 | 2021-05-01 | 公開日 | 2022-06-15 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Architecture of the cytoplasmic face of the nuclear pore. Science, 376, 2022
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6QPS
| Structural characterization of a mannuronic acid specific polysaccharide family 6 lyase enzyme from human gut microbiota | 分子名称: | ACETATE ION, CALCIUM ION, Polysaccharide Lyase Family 6 | 著者 | Fredslund, F, Stender, E.G.P, Svensson, B, Welner, D.H. | 登録日 | 2019-02-14 | 公開日 | 2019-09-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.287 Å) | 主引用文献 | Structural and functional aspects of mannuronic acid-specific PL6 alginate lyase from the human gut microbeBacteroides cellulosilyticus. J.Biol.Chem., 294, 2019
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7PGM
| HHIP-C in complex with heparin | 分子名称: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-3)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Hedgehog-interacting protein | 著者 | Griffiths, S.C, Schwab, R.A, El Omari, K, Bishop, B, Iverson, E.J, Malinuskas, T, Dubey, R, Qian, M, Covey, D.F, Gilbert, R.J.C, Rohatgi, R, Siebold, C. | 登録日 | 2021-08-14 | 公開日 | 2021-12-15 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Hedgehog-Interacting Protein is a multimodal antagonist of Hedgehog signalling. Nat Commun, 12, 2021
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6WPN
| Crystal structure of a putative oligosaccharide periplasmic-binding protein from Synechococcus sp. MITs9220 | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Substrate-binding protein | 著者 | Ford, B.A, Michie, K.A, Paulsen, I.T, Mabbutt, B.C, Shah, B.S. | 登録日 | 2020-04-27 | 公開日 | 2021-05-12 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Novel functional insights into a modified sugar-binding protein from Synechococcus MITS9220. Sci Rep, 12, 2022
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4KQZ
| structure of the receptor binding domain (RBD) of MERS-CoV spike | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, S protein | 著者 | Lu, G, Hu, Y, Wang, Q, Qi, J, Gao, F, Li, Y, Zhang, Y, Zhang, W, Yuan, Y, Bao, J, Zhang, B, Shi, Y, Yan, J, Gao, G.F. | 登録日 | 2013-05-15 | 公開日 | 2013-07-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.514 Å) | 主引用文献 | Molecular basis of binding between novel human coronavirus MERS-CoV and its receptor CD26. Nature, 500, 2013
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5LGJ
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8BPG
| FcMR binding at subunit Fcu3 of IgM pentamer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ... | 著者 | Chen, Q, Rosenthal, P, Tolar, P. | 登録日 | 2022-11-16 | 公開日 | 2023-04-12 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis for Fc receptor recognition of immunoglobulin M. Nat.Struct.Mol.Biol., 30, 2023
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6QKZ
| Full length GluA1/2-gamma8 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6-nitro-2,3-bis(oxidanylidene)-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide, ... | 著者 | Herguedas, B, Garcia-Nafria, J, Greger, I.G. | 登録日 | 2019-01-30 | 公開日 | 2019-03-27 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (6.3 Å) | 主引用文献 | Architecture of the heteromeric GluA1/2 AMPA receptor in complex with the auxiliary subunit TARP gamma 8. Science, 364, 2019
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8BPF
| FcMR binding at subunit Fcu1 of IgM pentamer | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ... | 著者 | Chen, Q, Rosenthal, P, Tolar, P. | 登録日 | 2022-11-16 | 公開日 | 2023-04-12 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis for Fc receptor recognition of immunoglobulin M. Nat.Struct.Mol.Biol., 30, 2023
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8BPE
| 8:1 binding of FcMR on IgM pentameric core | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ... | 著者 | Chen, Q, Rosenthal, P, Tolar, P. | 登録日 | 2022-11-16 | 公開日 | 2023-04-12 | 最終更新日 | 2023-07-26 | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | 主引用文献 | Structural basis for Fc receptor recognition of immunoglobulin M. Nat.Struct.Mol.Biol., 30, 2023
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6X5S
| Human Alpha-1,6-fucosyltransferase (FUT8) bound to GDP and A3'-Asn | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A3'-Asn, Alpha-(1,6)-fucosyltransferase, ... | 著者 | Kadirvelraj, R, Wood, Z.A. | 登録日 | 2020-05-26 | 公開日 | 2020-10-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Characterizing human alpha-1,6-fucosyltransferase (FUT8) substrate specificity and structural similarities with related fucosyltransferases. J.Biol.Chem., 295, 2020
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1E9Y
| Crystal structure of Helicobacter pylori urease in complex with acetohydroxamic acid | 分子名称: | ACETOHYDROXAMIC ACID, NICKEL (II) ION, UREASE SUBUNIT ALPHA, ... | 著者 | Ha, N.-C, Oh, S.-T, Oh, B.-H. | 登録日 | 2000-11-01 | 公開日 | 2001-11-01 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Supramolecular Assembly and Acid Resistance of Helicobacter Pylori Urease Nat.Struct.Biol., 8, 2001
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7OR0
| Cryo-EM structure of the human TRPA1 ion channel in complex with the antagonist 3-60, conformation 2 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Grieben, M, Pike, A.C.W, Saward, B.G, Wang, D, Mukhopadhyay, S.M.M, Moreira, T, Chalk, R, MacLean, E.M, Marsden, B.D, Burgess-Brown, N.A, Bountra, C, Schofield, C.J, Carpenter, E.P. | 登録日 | 2021-06-04 | 公開日 | 2022-06-22 | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | 主引用文献 | Cryo-EM structure of the human TRPA1 ion channel in complex with the antagonist 3-60 To Be Published
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4KGM
| Bacterial tRNA(HIS) Guanylyltransferase (Thg1)-Like Protein in complex with ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... | 著者 | Hyde, S.J, Rao, B.S, Eckenroth, B.E, Jackman, J.E, Doublie, S. | 登録日 | 2013-04-29 | 公開日 | 2013-08-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.361 Å) | 主引用文献 | Structural Studies of a Bacterial tRNA(HIS) Guanylyltransferase (Thg1)-Like Protein, with Nucleotide in the Activation and Nucleotidyl Transfer Sites. Plos One, 8, 2013
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1EF0
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5W78
| Human acyloxyacyl hydrolase (AOAH), proteolytically processed | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acyloxyacyl hydrolase, CALCIUM ION, ... | 著者 | Gorelik, A, Illes, K, Nagar, B. | 登録日 | 2017-06-19 | 公開日 | 2018-01-03 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.271 Å) | 主引用文献 | Crystal structure of the mammalian lipopolysaccharide detoxifier. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1EQP
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5WRY
| Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor | 分子名称: | N-[(3R)-1-(cyclopropylmethyl)pyrrolidin-3-yl]-5-[(2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl)methyl]-2-fluorobenzamide, Poly [ADP-ribose] polymerase 1 | 著者 | Cao, R, Wang, Y.L, Zhou, J, Huang, N, Xu, B.L. | 登録日 | 2016-12-04 | 公開日 | 2017-01-25 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor To Be Published
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5W9J
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1EED
| X-ray crystallographic analysis of inhibition of endothiapepsin by cyclohexyl renin inhibitors | 分子名称: | (2S)-2-[[(3S,4S)-5-cyclohexyl-4-[[(4S,5S)-5-[(2-methylpropan-2-yl)oxycarbonylamino]-4-oxidanyl-6-phenyl-hexanoyl]amino]-3-oxidanyl-pentanoyl]amino]-4-methyl-pentanoic acid, ENDOTHIAPEPSIN | 著者 | Blundell, T.L, Frazao, C, Cooper, J.B. | 登録日 | 1992-06-15 | 公開日 | 1994-01-31 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray crystallographic analysis of inhibition of endothiapepsin by cyclohexyl renin inhibitors. Biochemistry, 31, 1992
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1RER
| Crystal structure of the homotrimer of fusion glycoprotein E1 from Semliki Forest Virus. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-beta-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Gibbons, D.L, Vaney, M.C, Roussel, A, Vigouroux, A, Reilly, B, Kielian, M, Rey, F.A. | 登録日 | 2003-11-07 | 公開日 | 2004-01-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Conformational change and protein-protein interactions of the fusion protein of Semliki Forest virus. Nature, 427, 2004
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5W9P
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