PDB: 4050 件ウェブページステータス検索Chemie searchBIRD

---

1ES1	CRYSTAL STRUCTURE OF VAL61HIS MUTANT OF TRYPSIN-SOLUBILIZED FRAGMENT OF CYTOCHROME B5 分子名称: CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE 著者 Wu, J, Gan, J.-H, Xia, Z.-X, Wang, Y.-H, Wang, W.-H, Xue, L.-L, Xie, Y, Huang, Z.-X. 登録日 2000-04-07 公開日 2000-08-09 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of recombinant trypsin-solubilized fragment of cytochrome b(5) and the structural comparison with Val61His mutant. Proteins, 40, 2000
1HX2	SOLUTION STRUCTURE OF BSTI, A TRYPSIN INHIBITOR FROM BOMBINA BOMBINA. 分子名称: BSTI 著者 Rosengren, K.J, Daly, N.L, Scanlon, M.J, Craik, D.J. 登録日 2001-01-11 公開日 2001-01-24 最終更新日 2022-02-23 実験手法 SOLUTION NMR 主引用文献 Solution structure of BSTI: a new trypsin inhibitor from skin secretions of Bombina bombina. Biochemistry, 40, 2001
2AB9	Discovery, structural determination and processing of the precursor protein that produces the cyclic trypsin inhibitor SFTI-1 分子名称: pro-SFTI-1 著者 Mulvenna, J.P, Foley, F.M, Craik, D.J. 登録日 2005-07-15 公開日 2005-07-26 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 Discovery, structural determination and putative processing of the precursor protein that produces the cyclic trypsin inhibitor SFTI-1 J.Biol.Chem., 280, 2005
1LD5	STRUCTURE OF BPTI MUTANT A16V 分子名称: PANCREATIC TRYPSIN INHIBITOR 著者 Cierpicki, T, Otlewski, J. 登録日 2002-04-08 公開日 2002-09-11 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 NMR structures of two variants of bovine pancreatic trypsin inhibitor (BPTI) reveal unexpected influence of mutations on protein structure and stability. J.Mol.Biol., 321, 2002
1LD6	STRUCTURE OF BPTI_8A MUTANT 分子名称: PANCREATIC TRYPSIN INHIBITOR 著者 Cierpicki, T, Otlewski, J. 登録日 2002-04-08 公開日 2002-09-11 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 NMR structures of two variants of bovine pancreatic trypsin inhibitor (BPTI) reveal unexpected influence of mutations on protein structure and stability. J.Mol.Biol., 321, 2002
1PI2	REACTIVE SITES OF AN ANTICARCINOGENIC BOWMAN-BIRK PROTEINASE INHIBITOR ARE SIMILAR TO OTHER TRYPSIN INHIBITORS 分子名称: BOWMAN-BIRK INHIBITOR (PI-II) 著者 Chen, P, Rose, J, Wang, B.C. 登録日 1991-03-26 公開日 1992-04-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Reactive sites of an anticarcinogenic Bowman-Birk proteinase inhibitor are similar to other trypsin inhibitors. J.Biol.Chem., 267, 1992
1H34	Crystal structure of lima bean trypsin inhibitor 分子名称: BOWMAN-BIRK TYPE PROTEINASE INHIBITOR 著者 Debreczeni, J.E, Bunkoczi, G, Girmann, B, Sheldrick, G.M. 登録日 2002-08-21 公開日 2003-02-06 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 In-House Phase Determination of the Lima Bean Trypsin Inhibitor: A Low-Resolution Sulfur-Sad Case Acta Crystallogr.,Sect.D, 59, 2003
1B1U	CRYSTAL STRUCTURE OF THE BIFUNCTIONAL INHIBITOR RAGI 分子名称: PROTEIN (ALPHA-AMYLASE/TRYPSIN INHIBITOR RATI) 著者 Gourinath, S, Srinivasan, A, Singh, T.P. 登録日 1998-11-23 公開日 1998-12-02 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the bifunctional inhibitor of trypsin and alpha-amylase from ragi seeds at 2.2 A resolution. Acta Crystallogr.,Sect.D, 56, 2000
1C2A	CRYSTAL STRUCTURE OF BARLEY BBI 分子名称: BOWMAN-BIRK TRYPSIN INHIBITOR 著者 Song, H.K, Kim, Y.S, Yang, J.K, Moon, J, Lee, J.Y, Suh, S.W. 登録日 1999-07-23 公開日 1999-12-29 最終更新日 2022-12-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of a 16 kDa double-headed Bowman-Birk trypsin inhibitor from barley seeds at 1.9 A resolution. J.Mol.Biol., 293, 1999
1G6X	ULTRA HIGH RESOLUTION STRUCTURE OF BOVINE PANCREATIC TRYPSIN INHIBITOR (BPTI) MUTANT WITH ALTERED BINDING LOOP SEQUENCE 分子名称: 1,2-ETHANEDIOL, PANCREATIC TRYPSIN INHIBITOR, SULFATE ION 著者 Addlagatta, A, Czapinska, H, Krzywda, S, Otlewski, J, Jaskolski, M. 登録日 2000-11-08 公開日 2001-05-09 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (0.86 Å) 主引用文献 Ultrahigh-resolution structure of a BPTI mutant. Acta Crystallogr.,Sect.D, 57, 2001
1BPT	CREVICE-FORMING MUTANTS OF BPTI: CRYSTAL STRUCTURES OF F22A, Y23A, N43G, AND F45A 分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, PHOSPHATE ION 著者 Housset, D, Wlodawer, A, Tao, F, Fuchs, J, Woodward, C. 登録日 1991-12-11 公開日 1993-01-15 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crevice-forming mutants in the rigid core of bovine pancreatic trypsin inhibitor: crystal structures of F22A, Y23A, N43G, and F45A. Protein Sci., 2, 1993
6QU9	Fab fragment of an antibody that inhibits polymerisation of alpha-1-antitrypsin 分子名称: FAB 4B12 heavy chain, FAB 4B12 light chain, GLYCEROL, ... 著者 Jagger, A.M, Heyer-Chauhan, N, Lomas, D.A, Irving, J.A. 登録日 2019-02-26 公開日 2020-03-18 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The structural basis for Z alpha 1 -antitrypsin polymerization in the liver. Sci Adv, 6, 2020
8P4J	Alpha-1-antitrypsin - Sydney variant (G192C) 分子名称: Alpha-1-antitrypsin 著者 Kamuda, K, Lomas, D.A, Irving, J.A. 登録日 2023-05-22 公開日 2024-04-03 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate. Febs J., 291, 2024
8P4U	Alpha-1-antitrypsin - Sydney variant (G192C) 分子名称: Alpha-1-antitrypsin 著者 Kamuda, K, Lomas, D.A, Irving, J.A. 登録日 2023-05-23 公開日 2024-04-03 最終更新日 2024-07-17 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A novel pathological mutant reveals the role of torsional flexibility in the serpin breach in adoption of an aggregation-prone intermediate. Febs J., 291, 2024
8PI2	Native alpha-1-antitrypsin at 1.5 Angstrom (Cys232Ser) 分子名称: 1,2-ETHANEDIOL, Alpha-1-antitrypsin, DIMETHYL SULFOXIDE, ... 著者 Wang, M, Irving, J.A. 登録日 2023-06-20 公開日 2023-07-05 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Structural determinants of instability in alpha-1-antitrypsin To Be Published
6I1O	Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, FAB 2H2 heavy chain, FAB 2H2 light chain, ... 著者 Laffranchi, M, Elliston, E.L.K, Miranda, E, Perez, J, Fra, A, Lomas, D.A, Irving, J.A. 登録日 2018-10-29 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin. JCI Insight, 5, 2020
7AON	Crystal structure of CI2 double mutant L49I,I57V 分子名称: GLYCEROL, SULFATE ION, Subtilisin-chymotrypsin inhibitor-2A 著者 Olsen, J.G, Teilum, K, Hamborg, L, Roche, J.V. 登録日 2020-10-14 公開日 2020-12-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli. Commun Biol, 4, 2021
7A1H	Crystal structure of wild-type CI2 分子名称: SULFATE ION, Subtilisin-chymotrypsin inhibitor-2A 著者 Olsen, J.G, Teilum, K, Hamborg, L, Roche, J.V. 登録日 2020-08-13 公開日 2020-12-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli. Commun Biol, 4, 2021
7AOK	Crystal structure of CI2 mutant L49I 分子名称: SULFATE ION, Subtilisin-chymotrypsin inhibitor-2A 著者 Olsen, J.G, Teilum, K, Hamborg, L, Roche, J.V. 登録日 2020-10-14 公開日 2020-12-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Synergistic stabilization of a double mutant in chymotrypsin inhibitor 2 from a library screen in E. coli. Commun Biol, 4, 2021
4PYW	1.92 angstrom crystal structure of A1AT:TTAI ternary complex 分子名称: ACE-THR-THR-ALA-ILE-NH2, Alpha-1-antitrypsin, GLYCEROL 著者 Nyon, M.P, Day, J, Gooptu, B. 登録日 2014-03-28 公開日 2015-06-10 最終更新日 2022-08-24 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of alpha 1 -antitrypsin upon ligand binding. Protein Sci., 24, 2015
2SNV	THE REFINED STRUCTURE OF SINDBIS VIRUS CORE PROTEIN IN COMPARISON WITH OTHER CHYMOTRYPSIN-LIKE SERINE PROTEINASE STRUCTURES 分子名称: SINDBIS VIRUS COAT PROTEIN 著者 Tong, L, Rossmann, M.G. 登録日 1992-07-17 公開日 1993-10-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Refined structure of Sindbis virus core protein and comparison with other chymotrypsin-like serine proteinase structures. J.Mol.Biol., 230, 1993
1LVO	Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,4-DIETHYLENE DIOXIDE, Replicase, ... 著者 Anand, K, Palm, G.J, Mesters, J.R, Siddell, S.G, Ziebuhr, J, Hilgenfeld, R. 登録日 2002-05-29 公開日 2002-07-17 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Structure of coronavirus main proteinase reveals combination of a chymotrypsin fold with an extra alpha-helical domain. EMBO J., 21, 2002
2CI2	CRYSTAL AND MOLECULAR STRUCTURE OF THE SERINE PROTEINASE INHIBITOR CI-2 FROM BARLEY SEEDS 分子名称: CHYMOTRYPSIN INHIBITOR 2 著者 Mcphalen, C.A, James, M.N.G. 登録日 1988-09-05 公開日 1988-09-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal and molecular structure of the serine proteinase inhibitor CI-2 from barley seeds. Biochemistry, 26, 1987
6HSX	Thrombin in Complex with a D-Phe-Pro-diaminopyridine derivative 分子名称: (2~{S})-1-[(2~{R})-2-azanyl-3-phenyl-propanoyl]-~{N}-[[2,6-bis(azanyl)pyridin-4-yl]methyl]pyrrolidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... 著者 Ngo, K, Heine, A, Klebe, G. 登録日 2018-10-02 公開日 2019-10-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 Protein-Induced Change in Ligand Protonation during Trypsin and Thrombin Binding: Hint on Differences in Selectivity Determinants of Both Proteins? J.Med.Chem., 63, 2020
7JRX	Crystal structure of the R64F mutant of Bauhinia Bauhinioides complexed with Bovine Chymotrypsin 分子名称: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... 著者 Li, M, Wlodawer, A, Gustchina, A. 登録日 2020-08-13 公開日 2021-07-21 最終更新日 2021-08-11 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI. Acta Crystallogr D Struct Biol, 77, 2021

<20212223242526272829303132333435>