6I1O

Fab fragment of an antibody selective for wild-type alpha-1-antitrypsin

Summary for 6I1O

• Entry DOI: 10.2210/pdb6i1o/pdb
• Descriptor: FAB 2H2 heavy chain, FAB 2H2 light chain, SULFATE ION, ... (6 entities in total)
• Functional Keywords: antibody fragment, antitrypsin binding, diagnostic, monoclonal, protein binding, selective, wild-type, glu342, e342
• Biological source: Mus musculus; More
• Total number of polymer chains: 2
• Total formula weight: 47434.52

Authors

Laffranchi, M.,Elliston, E.L.K.,Miranda, E.,Perez, J.,Fra, A.,Lomas, D.A.,Irving, J.A. (deposition date: 2018-10-29, release date: 2019-11-20, Last modification date: 2024-01-24)

• Primary citation: Laffranchi, M.,Elliston, E.L.,Miranda, E.,Perez, J.,Ronzoni, R.,Jagger, A.M.,Heyer-Chauhan, N.,Brantly, M.L.,Fra, A.,Lomas, D.A.,Irving, J.A.; Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin.; JCI Insight, 5:-, 2020; PubMed: 32699193; DOI: 10.1172/jci.insight.135459

Experimental method

X-RAY DIFFRACTION (1.93 Å)