PDB: 2832 件ウェブページステータス検索Chemie searchBIRD

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3E0C	Crystal Structure of DNA Damage-Binding protein 1(DDB1) 分子名称: DNA damage-binding protein 1 著者 Amaya, M.F, Xu, L, Hao, H, Bountra, C, Wickstroem, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) 登録日 2008-07-31 公開日 2008-09-16 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Structure and function of WD40 domain proteins. Protein Cell, 2, 2011
2CRX	STRUCTURE OF THE HOLLIDAY JUNCTION INTERMEDIATE IN CRE-LOXP SITE-SPECIFIC RECOMBINATION 分子名称: DNA 35-MER, PROTEIN (CRE RECOMBINASE) 著者 Gopaul, D.N, Guo, F, Vanduyne, G.D. 登録日 1998-06-19 公開日 1999-12-14 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the Holliday junction intermediate in Cre-loxP site-specific recombination. EMBO J., 17, 1998
7Z6O	X-Ray studies of Ku70/80 reveal the binding site for IP6 分子名称: DNA (5'-D(*GP*TP*TP*TP*TP*TP*AP*GP*TP*TP*TP*AP*T)-3'), DNA (5'-D(P*AP*AP*AP*TP*AP*AP*AP*CP*TP*AP*AP*AP*AP*AP*C)-3'), INOSITOL HEXAKISPHOSPHATE, ... 著者 Varela, P.F, Charbonnier, J.B. 登録日 2022-03-14 公開日 2023-08-30 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Structural and functional basis of inositol hexaphosphate stimulation of NHEJ through stabilization of Ku-XLF interaction. Nucleic Acids Res., 51, 2023
8JNE	The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome without the linker DNA binding 分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ... 著者 Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. 登録日 2023-06-06 公開日 2024-03-27 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4.68 Å) 主引用文献 Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
8JND	The cryo-EM structure of the nonameric RAD51 ring bound to the nucleosome with the linker DNA binding 分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ... 著者 Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. 登録日 2023-06-06 公開日 2024-03-27 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.66 Å) 主引用文献 Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
7D8T	MITF bHLHLZ complex with M-box DNA 分子名称: DNA (5'-D(*TP*GP*TP*AP*AP*CP*AP*TP*GP*TP*GP*TP*CP*CP*CP*C)-3'), DNA (5'-D(P*GP*GP*GP*AP*CP*AP*CP*AP*TP*GP*TP*TP*AP*CP*AP*G)-3'), Microphthalmia-associated transcription factor,Methionyl-tRNA synthetase beta subunit 著者 Guo, M, Fang, P, Wang, J. 登録日 2020-10-09 公開日 2021-10-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.201 Å) 主引用文献 A unique hyperdynamic dimer interface permits small molecule perturbation of the melanoma oncoprotein MITF for melanoma therapy. Cell Res., 33, 2023
3W03	XLF-XRCC4 complex 分子名称: DNA repair protein XRCC4, Non-homologous end-joining factor 1 著者 Wu, Q, Ochi, T, Matak-Vinkovic, D, Robinson, C.V, Chirgadze, D.Y, Blundell, T.L. 登録日 2012-10-17 公開日 2012-11-07 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (8.492 Å) 主引用文献 Non-homologous end-joining partners in a helical dance: structural studies of XLF-XRCC4 interactions Biochem.Soc.Trans., 39, 2011
2R9A	Crystal structure of human XLF 分子名称: Non-homologous end-joining factor 1 著者 Andres, S.N, Junop, M.S. 登録日 2007-09-12 公開日 2008-01-01 最終更新日 2017-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal Structure of Human XLF: A Twist in Nonhomologous DNA End-Joining Mol.Cell, 28
3RWR	Crystal structure of the human XRCC4-XLF complex 分子名称: DNA repair protein XRCC4, HEXATANTALUM DODECABROMIDE, Non-homologous end-joining factor 1 著者 Andres, S.N, Junop, M.S. 登録日 2011-05-09 公開日 2011-12-07 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.943 Å) 主引用文献 Structure of human XLF-XRCC4: assembly of a functional DNA repair complex To be Published
6PAI	Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to RBM39 and sulfonamide E7820 分子名称: 3-cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DDB1- and CUL4-associated factor 15, ... 著者 Volkov, O.A, Du, X. 登録日 2019-06-11 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural Basis and Kinetic Pathway of RBM39 Recruitment to DCAF15 by a Sulfonamide Molecular Glue E7820. Structure, 27, 2019
6CIL	PRE-REACTION COMPLEX, RAG1(E962Q)/2-INTACT/INTACT 12/23RSS COMPLEX IN MN2+ 分子名称: High mobility group protein B1, Intact 12RSS substrate forward strand, Intact 12RSS substrate reverse strand, ... 著者 Chuenchor, W, Chen, X, Kim, M.S, Gellert, M, Yang, W. 登録日 2018-02-24 公開日 2018-04-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.15 Å) 主引用文献 Cracking the DNA Code for V(D)J Recombination. Mol. Cell, 70, 2018
7ODX	Cyanophage S-2L Succinoaminodeoxyadenylate synthetase (PurZ) bound to dGMP and dATP as an energy donor 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, Succinoaminodeoxyadenylate synthetase (PurZ) 著者 Czernecki, D, Delarue, M. 登録日 2021-04-30 公開日 2021-09-01 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.69617081 Å) 主引用文献 Characterization of a triad of genes in cyanophage S-2L sufficient to replace adenine by 2-aminoadenine in bacterial DNA. Nat Commun, 12, 2021
5D2M	Complex between human SUMO2-RANGAP1, UBC9 and ZNF451 分子名称: 1,2-ETHANEDIOL, Ran GTPase-activating protein 1, SUMO-conjugating enzyme UBC9, ... 著者 Cappadocia, L, Lima, C.D. 登録日 2015-08-05 公開日 2015-11-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for catalytic activation by the human ZNF451 SUMO E3 ligase. Nat.Struct.Mol.Biol., 22, 2015
7PMK	S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation I) 分子名称: Cell division control protein 45,Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA helicase, ... 著者 Jenkyn-Bedford, M, Yeeles, J.T.P, Deegan, T.D. 登録日 2021-09-02 公開日 2021-11-10 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 A conserved mechanism for regulating replisome disassembly in eukaryotes. Nature, 600, 2021
7PMN	S. cerevisiae replisome-SCF(Dia2) complex bound to double-stranded DNA (conformation II) 分子名称: Cell division control protein 45,Cell division control protein 45, Chromosome segregation in meiosis protein 3, DNA polymerase alpha-binding protein, ... 著者 Jenkyn-Bedford, M, Yeeles, J.T.P, Deegan, T.D. 登録日 2021-09-02 公開日 2021-11-10 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 A conserved mechanism for regulating replisome disassembly in eukaryotes. Nature, 600, 2021
7BY1	Crystal structure of GCN5 PCAF N-terminal domain 分子名称: Histone acetyltransferase KAT2A, ZINC ION 著者 Hibi, R, Toma-Fukai, S, Shimizu, T. 登録日 2020-04-21 公開日 2020-08-26 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of GCN5 PCAF N-terminal domain reveals atypical ubiquitin ligase structure. J.Biol.Chem., 295, 2020
8A58	X-ray structure of TRIM21 RING E3 ligase in complex with E2 enzyme Ube2W 分子名称: E3 ubiquitin-protein ligase TRIM21, Ubiquitin-conjugating enzyme E2 W, ZINC ION 著者 James, L.C, Kiss, L. 登録日 2022-06-14 公開日 2023-04-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates. Nat Commun, 14, 2023
7V7C	CryoEM structure of DDB1-VprBP-Vpr-UNG2(94-313) complex 分子名称: DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1, Protein Vpr, ... 著者 Wang, D, Xu, J, Liu, Q, Xiang, Y. 登録日 2021-08-21 公開日 2022-08-31 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural insights into the HIV-1 Vpr mediated ubiquitination through the Cullin-RING E3 ubiquitin ligase To Be Published
5KGF	Structural model of 53BP1 bound to a ubiquitylated and methylated nucleosome, at 4.5 A resolution 分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B type 1-C/E/F/G/I, ... 著者 Wilson, M.D, Benlekbir, S, Sicheri, F, Rubinstein, J.L, Durocher, D. 登録日 2016-06-13 公開日 2016-07-27 最終更新日 2020-01-15 実験手法 ELECTRON MICROSCOPY (4.54 Å) 主引用文献 The structural basis of modified nucleosome recognition by 53BP1. Nature, 536, 2016
6DSZ	Crystal structure of DDB1 in complex with DET1- and DDB1-associated protein 1 (DDA1) 分子名称: DET1- and DDB1-associated protein 1, DNA damage-binding protein 1 著者 Shabek, N, Zheng, N. 登録日 2018-06-14 公開日 2018-12-12 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.093 Å) 主引用文献 Structural insights into DDA1 function as a core component of the CRL4-DDB1 ubiquitin ligase. Cell Discov, 4, 2018
6TTU	Ubiquitin Ligation to substrate by a cullin-RING E3 ligase at 3.7A resolution: NEDD8-CUL1-RBX1 N98R-SKP1-monomeric b-TRCP1dD-IkBa-UB~UBE2D2 分子名称: CYS-LYS-LYS-ALA-ARG-HIS-ASP-SEP-GLY, Cullin-1, E3 ubiquitin-protein ligase RBX1, ... 著者 Baek, K, Prabu, J.R, Schulman, B.A. 登録日 2019-12-30 公開日 2020-02-12 最終更新日 2020-03-04 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 NEDD8 nucleates a multivalent cullin-RING-UBE2D ubiquitin ligation assembly. Nature, 578, 2020
4WQO	Structure of VHL-EloB-EloC-Cul2 分子名称: Cullin-2, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2, ... 著者 Nguyen, H.C, Xiong, Y. 登録日 2014-10-22 公開日 2015-03-04 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Insights into Cullin-RING E3 Ubiquitin Ligase Recruitment: Structure of the VHL-EloBC-Cul2 Complex. Structure, 23, 2015
7V7B	CryoEM structure of DDB1-VprBP complex in ARM-up conformation 分子名称: DDB1- and CUL4-associated factor 1, DNA damage-binding protein 1 著者 Wang, D, Xu, J, Liu, Q, Xiang, Y. 登録日 2021-08-21 公開日 2022-08-31 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural insights into the HIV-1 Vpr mediated ubiquitination through the Cullin-RING E3 ubiquitin ligase To Be Published
8WQD	Local refinement of FEM1B bound with the C-degron of CCC89 分子名称: Coiled-coil domain-containing protein 89, Protein fem-1 homolog B 著者 Chen, X, Zhang, K, Xu, C. 登録日 2023-10-11 公開日 2024-04-03 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.55 Å) 主引用文献 Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024
8WQI	Local refinement of FEM1B bound with the C-degron of CUX1 分子名称: Protein CASP, Protein fem-1 homolog B 著者 Chen, X, Zhang, K, Xu, C. 登録日 2023-10-11 公開日 2024-04-03 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase. Nat Commun, 15, 2024

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