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2ST1
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THE THREE-DIMENSIONAL STRUCTURE OF BACILLUS AMYLOLIQUEFACIENS SUBTILISIN AT 1.8 ANGSTROMS AND AN ANALYSIS OF THE STRUCTURAL CONSEQUENCES OF PEROXIDE INACTIVATION
分子名称: CALCIUM ION, SUBTILISIN BPN', SULFATE ION
著者Bott, R.
登録日1990-05-11
公開日1991-07-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The three-dimensional structure of Bacillus amyloliquefaciens subtilisin at 1.8 A and an analysis of the structural consequences of peroxide inactivation.
J.Biol.Chem., 263, 1988
2SHP
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TYROSINE PHOSPHATASE SHP-2
分子名称: DODECANE-TRIMETHYLAMINE, SHP-2
著者Hof, P, Pluskey, S, Dhe-Paganon, S, Eck, M.J, Shoelson, S.E.
登録日1997-12-01
公開日1999-02-16
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of the tyrosine phosphatase SHP-2.
Cell(Cambridge,Mass.), 92, 1998
2STW
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BU of 2stw by Molmil
SOLUTION NMR STRUCTURE OF THE HUMAN ETS1/DNA COMPLEX, RESTRAINED REGULARIZED MEAN STRUCTURE
分子名称: DNA (5'-D(*TP*CP*GP*AP*AP*CP*TP*TP*CP*CP*GP*GP*CP*TP*CP*GP*A)-3'), DNA (5'-D(*TP*CP*GP*AP*GP*CP*CP*GP*GP*AP*AP*GP*TP*TP*CP*GP*A)-3'), ETS1
著者Clore, G.M, Werner, M.H, Gronenborn, A.M.
登録日1996-08-05
公開日1997-03-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Correction of the NMR structure of the ETS1/DNA complex.
J.Biomol.NMR, 10, 1997
2UZ5
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BU of 2uz5 by Molmil
Solution structure of the fkbp-domain of Legionella pneumophila Mip
分子名称: MACROPHAGE INFECTIVITY POTENTIATOR
著者Ceymann, A, Horstmann, M, Ehses, P, Schweimer, K, Steinert, M, Kamphausen, T, Fischer, G, Hacker, J, Rosch, P, Faber, C.
登録日2007-04-25
公開日2007-06-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Domain Motions of the Mip Protein from Legionella Pneumophila
Biochemistry, 45, 2006
2UWN
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Crystal structure of Human Complement Factor H, SCR domains 6-8 (H402 risk variant), in complex with ligand.
分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ACETATE ION, CHLORIDE ION, ...
著者Prosser, B.E, Johnson, S, Roversi, P, Herbert, A.P, Blaum, B.S, Tyrrell, J, Jowitt, T.A, Clark, S.J, Terelli, E, Uhrin, D, Barlow, P.N, Sim, R.B, Day, A.J, Lea, S.M.
登録日2007-03-22
公開日2007-10-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for Complement Factor H Linked Age-Related Macular Degeneration.
J.Exp.Med., 204, 2007
2UUY
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BU of 2uuy by Molmil
Structure of a tick tryptase inhibitor in complex with bovine trypsin
分子名称: CALCIUM ION, CATIONIC TRYPSIN, CHLORIDE ION, ...
著者Siebold, C, Paesen, G.C, Harlos, K, Peacey, M.F, Nuttall, P.A, Stuart, D.I.
登録日2007-03-08
公開日2007-04-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献A Tick Protein with a Modified Kunitz Fold Inhibits Human Tryptase.
J.Mol.Biol., 368, 2007
4LMV
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BU of 4lmv by Molmil
Crystal structure of glutathione transferase GSTFuA2 from Phanerochaete chrysosporium
分子名称: ACETATE ION, CITRATE ANION, Glutathione transferase
著者Didierjean, C, Favier, F, Prosper, P.
登録日2013-07-11
公開日2014-05-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.204 Å)
主引用文献Diversification of fungal specific class a glutathione transferases in saprotrophic fungi.
Plos One, 8, 2013
5MQQ
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Transcriptional repressor AmtR of corynebacterium glutamicum
分子名称: AmtR protein, SULFATE ION
著者Sevvana, M, Hasselt, K, Muller, Y.A.
登録日2016-12-20
公開日2017-03-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.093 Å)
主引用文献Similarities in the structure of the transcriptional repressor AmtR in two different space groups suggest a model for the interaction with GlnK.
Acta Crystallogr F Struct Biol Commun, 73, 2017
4LDD
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BU of 4ldd by Molmil
Crystal Structure of Ebola virus VP40 Hexamer
分子名称: Matrix protein VP40
著者Bornholdt, Z.A, Ableson, D.M, Saphire, E.O.
登録日2013-06-24
公開日2013-08-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.498 Å)
主引用文献Structural Rearrangement of Ebola Virus VP40 Begets Multiple Functions in the Virus Life Cycle.
Cell(Cambridge,Mass.), 154, 2013
6AJD
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BU of 6ajd by Molmil
Crystal structure of a monometallic dihydropyrimidinase from Pseudomonas aeruginosa PAO1 reveals no lysine carbamylation within the active site
分子名称: D-hydantoinase/dihydropyrimidinase, ZINC ION
著者Huang, Y.H, Huang, C.Y.
登録日2018-08-27
公開日2018-10-24
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.223 Å)
主引用文献Crystal structures of monometallic dihydropyrimidinase and the human dihydroorotase domain K1556A mutant reveal no lysine carbamylation within the active site
Biochem. Biophys. Res. Commun., 505, 2018
3P90
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Crystal Structure Analysis of H207F Mutant of Human CLIC1
分子名称: Chloride intracellular channel protein 1
著者Cross, M.O, Fanucchi, S, Achilonu, I.A, Fernandes, M.A, Dirr, H.W.
登録日2010-10-15
公開日2010-11-03
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Role of individual histidines in the pH-dependent global stability of human chloride intracellular channel 1.
Biochemistry, 51, 2012
6ALD
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BU of 6ald by Molmil
RABBIT MUSCLE ALDOLASE A/FRUCTOSE-1,6-BISPHOSPHATE COMPLEX
分子名称: 1,6-FRUCTOSE DIPHOSPHATE (LINEAR FORM), FRUCTOSE-1,6-BIS(PHOSPHATE) ALDOLASE
著者Choi, K.H, Mazurkie, A.S, Morris, A.J, Utheza, D, Tolan, D.R, Allen, K.N.
登録日1998-12-23
公開日2000-01-05
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of a fructose-1,6-bis(phosphate) aldolase liganded to its natural substrate in a cleavage-defective mutant at 2.3 A(,).
Biochemistry, 38, 1999
6B84
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Crystal structure of Myotoxin II from Bothrops moojeni
分子名称: Basic phospholipase A2 homolog 2, SULFATE ION
著者Salvador, G.H.M, dos Santos, J.I, Fontes, M.R.M.
登録日2017-10-05
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献Structural evidence for a fatty acid-independent myotoxic mechanism for a phospholipase A2-like toxin.
Biochim Biophys Acta Proteins Proteom, 1866, 2018
6B80
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Crystal structure of myotoxin II from Bothrops moojeni complexed to myristic acid
分子名称: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Basic phospholipase A2 homolog 2, MYRISTIC ACID, ...
著者Salvador, G.H.M, dos Santos, J.I, Fontes, M.R.M.
登録日2017-10-05
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献Structural evidence for a fatty acid-independent myotoxic mechanism for a phospholipase A2-like toxin.
Biochim Biophys Acta Proteins Proteom, 1866, 2018
6B81
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Crystal structure of Myotoxin II from Bothrops moojeni complexed to Caprylic acid
分子名称: Basic phospholipase A2 homolog 2, OCTANOIC ACID (CAPRYLIC ACID), SULFATE ION
著者Salvador, G.H.M, dos Santos, J.I, Fontes, M.R.M.
登録日2017-10-05
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structural evidence for a fatty acid-independent myotoxic mechanism for a phospholipase A2-like toxin.
Biochim Biophys Acta Proteins Proteom, 1866, 2018
4E1G
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BU of 4e1g by Molmil
X-ray crystal structure of alpha-linolenic acid bound to the cyclooxygenase channel of cyclooxygenase-2
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Vecchio, A.J, Malkowski, M.G.
登録日2012-03-06
公開日2012-04-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Investigating Substrate Promiscuity in Cyclooxygenase-2: THE ROLE OF ARG-120 AND RESIDUES LINING THE HYDROPHOBIC GROOVE.
J.Biol.Chem., 287, 2012
4CBQ
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BU of 4cbq by Molmil
Crystal structure of the thioredoxin reductase from Entamoeba histolytica with auranofin Au(I) bound to Cys286
分子名称: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GOLD ION, ...
著者Parsonage, D, Kells, P.M, Hirata, K, Debnath, A, Poole, L.B, McKerrow, J.H, Reed, S.L, Podust, L.M.
登録日2013-10-16
公開日2014-11-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献X-Ray Structures of Thioredoxin and Thioredoxin Reductase from Entamoeba Histolytica and Prevailing Hypothesis of the Mechanism of Auranofin Action.
J.Struct.Biol., 194, 2016
6B83
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Crystal structure of Myotoxin II from Bothrops moojeni complexed to Caproic acid
分子名称: Basic phospholipase A2 homolog 2, HEXANOIC ACID, SULFATE ION
著者Salvador, G.H.M, dos Santos, J.I, Fontes, M.R.M.
登録日2017-10-05
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural evidence for a fatty acid-independent myotoxic mechanism for a phospholipase A2-like toxin.
Biochim Biophys Acta Proteins Proteom, 1866, 2018
5UJL
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Representative 1-conformer ensembles of K27-linked Ub2 from RDC data
分子名称: Ubiquitin
著者Castaneda, C.A, Fushman, D.
登録日2017-01-18
公開日2017-10-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Linkage via K27 Bestows Ubiquitin Chains with Unique Properties among Polyubiquitins.
Structure, 24, 2016
3PSG
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THE HIGH RESOLUTION CRYSTAL STRUCTURE OF PORCINE PEPSINOGEN
分子名称: PEPSINOGEN
著者Hartsuck, J.A, Koelsch, G, Remington, S.J.
登録日1991-09-03
公開日1993-01-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The high-resolution crystal structure of porcine pepsinogen.
Proteins, 13, 1992
3QE0
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A Galpha-i1 P-loop mutation prevents transition to the activated state
分子名称: GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-1, KB752 peptide, ...
著者Bosch, D.E, Willard, F.S, Kimple, A.J, Miley, M.J, Siderovski, D.P.
登録日2011-01-19
公開日2012-01-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A P-loop Mutation in Galpha Subunits Prevents Transition to the Active State: Implications for G-protein Signaling in Fungal Pathogenesis
Plos Pathog., 8, 2012
7SCT
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Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL16
分子名称: C-C motif chemokine 16, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-29
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
8XNG
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Cryo-EM structure of OSCA1.2-liposome-inside-out closed state
分子名称: Calcium permeable stress-gated cation channel 1
著者Zhang, Y, Han, Y.
登録日2023-12-29
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.56 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024
8YRU
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Crystal structure of D-amino acid transaminase from Haliscomenobacter hydrossis (apo form) after 15 sec of soaking with phenylhydrazine
分子名称: ACETATE ION, Aminotransferase class IV, [6-methyl-5-oxidanyl-4-[(2-phenylhydrazinyl)methyl]pyridin-3-yl]methyl dihydrogen phosphate
著者Matyuta, I.O, Bakunova, A.K, Minyaev, M.E, Popov, V.O, Boyko, K.M.
登録日2024-03-21
公開日2024-04-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of D-amino acid transaminase from Haliscomenobacter hydrossis (apo form) after 15 sec of soaking with phenylhydrazine
To Be Published
8XVZ
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Cryo-EM structure of OSCA3.1-2E(R611E-R619E)-closed/'desensitized' state
分子名称: CSC1-like protein ERD4
著者Zhang, Y, Han, Y.
登録日2024-01-15
公開日2024-04-10
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献Mechanical activation opens a lipid-lined pore in OSCA ion channels.
Nature, 628, 2024

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