PDB: 245663 件ウェブページステータス検索Chemie searchBIRD

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1IE7	PHOSPHATE INHIBITED BACILLUS PASTEURII UREASE CRYSTAL STRUCTURE 分子名称: NICKEL (II) ION, PHOSPHATE ION, UREASE ALPHA SUBUNIT, ... 著者 Benini, S, Rypniewski, W.R, Wilson, K.S, Ciurli, S, Mangani, S. 登録日 2001-04-09 公開日 2001-04-25 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structure-based rationalization of urease inhibition by phosphate: novel insights into the enzyme mechanism. J.Biol.Inorg.Chem., 6, 2001
7D9O	Crystal Structure of Recombinant Human Acetylcholinesterase in Complex with Compound 2 分子名称: (2R)-2-[[4-fluoranyl-1-[(4-fluorophenyl)methyl]piperidin-4-yl]methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase 著者 Liu, Q.F, Yin, W.C. 登録日 2020-10-14 公開日 2021-08-25 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate. J.Med.Chem., 64, 2021
7D9Q	Crystal Structure of Recombinant Human Acetylcholinesterase in Complex with Compound 7 分子名称: (2S)-2-[[4-fluoranyl-1-[(3-fluorophenyl)methyl]piperidin-4-yl]methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase 著者 Liu, Q.F, Yin, W.C. 登録日 2020-10-14 公開日 2021-08-25 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate. J.Med.Chem., 64, 2021
4HXD	Diversity of ubiquitin and ISG15 specificity amongst nairoviruses viral ovarian tumor domain proteases 分子名称: 1.7.6 3-bromanylpropan-1-amine, Polyubiquitin-C, RNA-directed RNA polymerase L, ... 著者 Capodagli, G.C, Pegan, S.D. 登録日 2012-11-09 公開日 2013-02-13 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Diversity of Ubiquitin and ISG15 Specificity among Nairoviruses' Viral Ovarian Tumor Domain Proteases. J.Virol., 87, 2013
1USQ	Complex of E. Coli DraE adhesin with Chloramphenicol 分子名称: 1,2-ETHANEDIOL, CHLORAMPHENICOL, DR HEMAGGLUTININ STRUCTURAL SUBUNIT, ... 著者 Anderson, K.L, Billington, J, Pettigrew, D, Cota, E, Roversi, P, Simpson, P, Chen, H.A, Urvil, P, Dumerle, L, Barlow, P, Medof, E, Smith, R.A.G, Nowicki, B, Le Bouguenec, C, Lea, S.M, Matthews, S. 登録日 2003-11-27 公開日 2004-08-31 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 High Resolution Studies of the Afa/Dr Adhesin Drae and its Interaction with Chloramphenicol J.Biol.Chem., 279, 2004
2NM2	Crystal structure of dihydroneopterin aldolase from S. aureus in complex with (1S,2R)-neopterin at 1.50 Angstrom resolution 分子名称: Dihydroneopterin aldolase, L-NEOPTERIN 著者 Blaszczyk, J, Ji, X, Yan, H. 登録日 2006-10-20 公開日 2007-09-04 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis for the aldolase and epimerase activities of Staphylococcus aureus dihydroneopterin aldolase. J.Mol.Biol., 368, 2007
3OPY	Crystal structure of Pichia pastoris phosphofructokinase in the T-state 分子名称: 6-phosphofructo-1-kinase alpha-subunit, 6-phosphofructo-1-kinase beta-subunit, 6-phosphofructo-1-kinase gamma-subunit, ... 著者 Strater, N, Marek, S, Kuettner, E.B, Kloos, M, Keim, A, Bruser, A, Kirchberger, J, Schoneberg, T. 登録日 2010-09-02 公開日 2010-10-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Molecular architecture and structural basis of allosteric regulation of eukaryotic phosphofructokinases. Faseb J., 25, 2011
3OUG	Crystal structure of cleaved L-aspartate-alpha-decarboxylase from Francisella tularensis 分子名称: Aspartate 1-decarboxylase, CHLORIDE ION, GLYCEROL 著者 Nocek, B, Gu, M, Papazisi, L, Anderson, W, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-09-14 公開日 2010-10-20 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Crystal structure of cleaved L-aspartate-alpha-decarboxylase from Francisella tularensis To be Published
2WIK	NONAGED FORM OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY TABUN ANALOGUE TA6 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... 著者 Carletti, E, Aurbek, N, Gillon, E, Loiodice, M, Nicolet, Y, Fontecilla, J, Masson, P, Thiermann, H, Nachon, F, Worek, F. 登録日 2009-05-12 公開日 2009-05-19 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure-activity analysis of aging and reactivation of human butyrylcholinesterase inhibited by analogues of tabun. Biochem. J., 421, 2009
4MN8	Crystal structure of flg22 in complex with the FLS2 and BAK1 ectodomains 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1, ... 著者 Chai, J, Sun, Y, Han, Z. 登録日 2013-09-10 公開日 2013-12-04 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.062 Å) 主引用文献 Structural basis for flg22-induced activation of the Arabidopsis FLS2-BAK1 immune complex. Science, 342, 2013
4IA3	Diastereotopic and Deuterium Effects in Gemini 分子名称: 21-NOR-9,10-SECOCHOLESTA-5,7,10(19)-TRIENE-1,3,25-TRIOL, 20-(4-HYDROXY-4-METHYLPENTYL)-, (1A,3B,5Z,7E), ... 著者 Maehr, H, Rochel, N, Suh, N, Uskokovic, M. 登録日 2012-12-06 公開日 2013-04-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Diastereotopic and deuterium effects in gemini. J.Med.Chem., 56, 2013
2NN1	Structure of inhibitor binding to Carbonic Anhydrase I 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[4-(AMINOSULFONYL)PHENYL]PROPANOIC ACID, Carbonic anhydrase 1, ... 著者 Christianson, D.W, Jude, K.M. 登録日 2006-10-23 公開日 2007-04-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Structural Analysis of Charge Discrimination in the Binding of Inhibitors to Human Carbonic Anhydrases I and II J.Am.Chem.Soc., 129, 2007
2A74	Human Complement Component C3c 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose, Complement Component C3c, GLYCEROL, ... 著者 Janssen, B.J.C, Huizinga, E.G, Raaijmakers, H.C.A, Roos, A, Daha, M.R, Nilsson-Ekdahl, K, Nilsson, B, Gros, P. 登録日 2005-07-04 公開日 2005-09-27 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of complement component C3 provide insights into the function and evolution of immunity. Nature, 437, 2005
2NP1	CRYSTAL STRUCTURE OF NITROPHORIN 1 FROM RHODNIUS PROLIXUS 分子名称: AMMONIUM ION, DIHYDROGENPHOSPHATE ION, NITROPHORIN 1, ... 著者 Weichsel, A, Montfort, W.R. 登録日 1998-01-19 公開日 1998-05-27 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of a nitric oxide transport protein from a blood-sucking insect. Nat.Struct.Biol., 5, 1998
3P9C	Crystal structure of perennial ryegrass LpOMT1 bound to SAH 分子名称: (2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, 1,2-ETHANEDIOL, ACETATE ION, ... 著者 Louie, G.V, Noel, J.P, Bowman, M.E. 登録日 2010-10-17 公開日 2011-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-Function Analyses of a Caffeic Acid O-Methyltransferase from Perennial Ryegrass Reveal the Molecular Basis for Substrate Preference. Plant Cell, 22, 2010
3P35	Polo-like kinase I Polo-box domain in complex with MQSpSPL phosphopeptide 分子名称: GLYCEROL, Serine/threonine-protein kinase PLK1, phosphopeptide 著者 Sledz, P, Hyvonen, M, Abell, C. 登録日 2010-10-04 公開日 2011-04-27 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 From crystal packing to molecular recognition: prediction and discovery of a binding site on the surface of polo-like kinase 1 Angew.Chem.Int.Ed.Engl., 50, 2011
7DGH	The co-crystal structure of SARS-CoV-2 main protease with peptidomimetic inhibitor N-((S)-3-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopiperidin-3-yl)propan-2-yl)amino)pentan-2-yl)amino)-1-oxobutan-2-yl)-2-naphthamide 分子名称: 3C-like proteinase, ~{N}-[(2~{S})-3-methyl-1-[[(2~{S})-4-methyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]naphthalene-2-carboxamide 著者 Shang, L.Q, Wang, H. 登録日 2020-11-11 公開日 2021-11-24 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.968 Å) 主引用文献 The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate. Eur.J.Med.Chem., 238, 2022
1B8W	DEFENSIN-LIKE PEPTIDE 1 分子名称: PROTEIN (DEFENSIN-LIKE PEPTIDE 1) 著者 Torres, A.M, Wang, X, Fletcher, J.I, Alewood, D, Alewood, P.F, Smith, R, Simpson, R.J, Nicholson, G.M, Sutherland, S.K, Gallagher, C.H, King, G.F, Kuchel, P.W. 登録日 1999-02-02 公開日 1999-09-15 最終更新日 2024-10-16 実験手法 SOLUTION NMR 主引用文献 Solution structure of a defensin-like peptide from platypus venom. Biochem.J., 341, 1999
7DGI	The co-crystal structure of SARS-CoV-2 main protease with peptidomimetic inhibitor N-((S)-3-methyl-1-(((S)-4-methyl-1-oxo-1-(((S)-1-oxo-3-((S)-2-oxopiperidin-3-yl)propan-2-yl)amino)pentan-2-yl)amino)-1-oxobutan-2-yl)-4-nitrobenzamide 分子名称: 3C-like proteinase, ~{N}-[(2~{S})-3-methyl-1-[[(2~{S})-4-methyl-1-oxidanylidene-1-[[(2~{S})-1-oxidanylidene-3-[(3~{S})-2-oxidanylidenepiperidin-3-yl]propan-2-yl]amino]pentan-2-yl]amino]-1-oxidanylidene-butan-2-yl]-4-nitro-benzamide 著者 Shang, L.Q, Wang, H. 登録日 2020-11-11 公開日 2021-11-24 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.898 Å) 主引用文献 The structure-based design of peptidomimetic inhibitors against SARS-CoV-2 3C like protease as Potent anti-viral drug candidate. Eur.J.Med.Chem., 238, 2022
3LJZ	Crystal Structure of Human MMP-13 complexed with an Amino-2-indanol compound 分子名称: (2R)-2-[4-(1,3-benzodioxol-5-yl)benzyl]-N~4~-hydroxy-N~1~-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]butanediamide, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Shieh, H.-S, Kiefer, J.R. 登録日 2010-01-26 公開日 2011-02-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure analysis reveals the flexibility of the ADAMTS-5 active site. Protein Sci., 20, 2011
6JGD	Crystal structure of barley exohydrolaseI W286Y mutant in complex with methyl 6-thio-beta-gentiobioside 分子名称: ACETATE ION, BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1, GLYCEROL, ... 著者 Luang, S, Streltsov, V.A, Hrmova, M. 登録日 2019-02-13 公開日 2020-08-19 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.13 Å) 主引用文献 The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases. Nat Commun, 13, 2022
6JGP	Crystal structure of barley exohydrolaseI W434H mutant in complex with methyl 6-thio-beta-gentiobioside. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO, ... 著者 Luang, S, Streltsov, V.A, Hrmova, M. 登録日 2019-02-14 公開日 2020-08-19 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 The evolutionary advantage of an aromatic clamp in plant family 3 glycoside exo-hydrolases. Nat Commun, 13, 2022
2AB0	Crystal Structure of E. coli protein YajL (ThiJ) 分子名称: YajL 著者 Wilson, M.A, Ringe, D, Petsko, G.A. 登録日 2005-07-14 公開日 2005-10-11 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 The Atomic Resolution Crystal Structure of the YajL (ThiJ) Protein from Escherichia coli: A Close Prokaryotic Homologue of the Parkinsonism-associated Protein DJ-1. J.Mol.Biol., 353, 2005
3ONF	Crystal structure of Lupinus luteus S-adenosyl-L-homocysteine hydrolase in complex with cordycepin 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3'-DEOXYADENOSINE, Adenosylhomocysteinase, ... 著者 Brzezinski, K, Jaskolski, M. 登録日 2010-08-28 公開日 2011-08-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus). Acta Crystallogr.,Sect.D, 68, 2012
2J5Y	Crystal structure of the GA module from F.magna 分子名称: PEPTOSTREPTOCOCCAL ALBUMIN-BINDING PROTEIN 著者 Lejon, S, Cramer, J.F, Nordberg, P.A, Lundqvist, T, Valegard, K. 登録日 2006-09-20 公開日 2007-06-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal Structure of a Bacterial Albumin-Binding Domain at 1.4A Resolution. FEBS Lett., 581, 2007

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