PDB: 664 件ウェブページステータス検索Chemie searchBIRD

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7QP6	Structure of the human 48S initiation complex in open state (h48S AUG open) 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Yi, S.-H, Petrychenko, V, Schliep, J.E, Goyal, A, Linden, A, Chari, A, Urlaub, H, Stark, H, Rodnina, M.V, Adio, S, Fischer, N. 登録日 2022-01-03 公開日 2022-05-11 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Conformational rearrangements upon start codon recognition in human 48S translation initiation complex. Nucleic Acids Res., 50, 2022
8Y0X	Dormant ribosome with SERBP1 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Du, M, Zeng, F. 登録日 2024-01-23 公開日 2024-02-07 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes. Front Mol Biosci, 11, 2024
8Y0W	dormant ribosome with eIF5A, eEF2 and SERBP1 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Du, M, Zeng, F. 登録日 2024-01-23 公開日 2024-02-07 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Implication of Stm1 in the protection of eIF5A, eEF2 and tRNA through dormant ribosomes. Front Mol Biosci, 11, 2024
8XXN	Cryo-EM structure of the human 43S ribosome with PDCD4 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. 登録日 2024-01-18 公開日 2024-05-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
8XXL	Cryo-EM structure of the human 40S ribosome with PDCD4 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. 登録日 2024-01-18 公開日 2024-05-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
8XXM	Cryo-EM structure of the human 40S ribosome with PDCD4 and eIF3G 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ye, X, Huang, Z, Li, Y, Wang, M, Cheng, J. 登録日 2024-01-18 公開日 2024-05-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Human tumor suppressor PDCD4 directly interacts with ribosomes to repress translation. Cell Res., 34, 2024
8XSY	Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled) 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Li, X, Wang, M, Cheng, J. 登録日 2024-01-10 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
8XSX	Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Li, X, Wang, M, Cheng, J. 登録日 2024-01-10 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
8YOO	Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Li, X, Wang, M, Denk, T, Cheng, J. 登録日 2024-03-13 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
8XSZ	Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Li, X, Wang, M, Cheng, J. 登録日 2024-01-10 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
8YOP	Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline 分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... 著者 Li, X, Wang, M, Denk, T, Cheng, J. 登録日 2024-03-13 公開日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.2 Å) 主引用文献 Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
7QZ6	Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5-fluoroTrp 分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
7QZ8	Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp 分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
7QZ7	Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5,6,7-trifluoroTrp 分子名称: DAUNOMYCIN, Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
7QZ9	Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp 分子名称: Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
7QZ5	Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5-fluoroTrp 分子名称: Transcriptional regulator, PadR-like family 著者 Thunnissen, A.M.W.H. 登録日 2022-01-30 公開日 2022-11-23 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144, 2022
5LKS	Structure-function insights reveal the human ribosome as a cancer target for antibiotics 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... 著者 Myasnikov, A.G, Natchiar, S.K, Nebout, M, Hazemann, I, Imbert, V, Khatter, H, Peyron, J.-F, Klaholz, B.P. 登録日 2016-07-23 公開日 2017-04-26 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure-function insights reveal the human ribosome as a cancer target for antibiotics. Nat Commun, 7, 2016
6IP5	Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. 登録日 2018-11-02 公開日 2019-05-29 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 HCV IRES Captures an Actively Translating 80S Ribosome. Mol.Cell, 74, 2019
6IP8	Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. 登録日 2018-11-02 公開日 2019-05-29 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 HCV IRES Captures an Actively Translating 80S Ribosome. Mol.Cell, 74, 2019
6IP6	Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii) 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. 登録日 2018-11-02 公開日 2019-05-29 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 HCV IRES Captures an Actively Translating 80S Ribosome. Mol.Cell, 74, 2019
5AJ0	Cryo electron microscopy of actively translating human polysomes (POST state). 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Behrmann, E, Loerke, J, Budkevich, T.V, Yamamoto, K, Schmidt, A, Penczek, P.A, Vos, M.R, Burger, J, Mielke, T, Scheerer, P, Spahn, C.M.T. 登録日 2015-02-19 公開日 2015-05-20 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural Snapshots of Actively Translating Human Ribosomes Cell(Cambridge,Mass.), 161, 2015
6ZUO	Human RIO1(kd)-StHA late pre-40S particle, structural state A (pre 18S rRNA cleavage) 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Plassart, L, Shayan, R, Plisson-Chastang, C. 登録日 2020-07-23 公開日 2021-05-12 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The final step of 40S ribosomal subunit maturation is controlled by a dual key lock. Elife, 10, 2021
6ZV6	Human RIO1(kd)-StHA late pre-40S particle, structural state B (post 18S rRNA cleavage) 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Plassart, L, Shayan, R, Plisson-Chastang, C. 登録日 2020-07-24 公開日 2021-05-12 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 The final step of 40S ribosomal subunit maturation is controlled by a dual key lock. Elife, 10, 2021
6ZVH	EDF1-ribosome complex 分子名称: 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Best, K.M, Denk, T, Cheng, J, Thoms, M, Berninghausen, O, Beckmann, R. 登録日 2020-07-24 公開日 2020-08-19 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 EDF1 coordinates cellular responses to ribosome collisions. Elife, 9, 2020
6ZXE	Cryo-EM structure of a late human pre-40S ribosomal subunit - State F2 分子名称: 40S ribosomal protein S10, 40S ribosomal protein S11, 40S ribosomal protein S12, ... 著者 Ameismeier, M, Zemp, I, van den Heuvel, J, Thoms, M, Berninghausen, O, Kutay, U, Beckmann, R. 登録日 2020-07-29 公開日 2020-12-02 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural basis for the final steps of human 40S ribosome maturation. Nature, 587, 2020

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