6FSH
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![BU of 6fsh by Molmil](/molmil-images/mine/6fsh) | Crystal structure of hybrid P450 OxyBtei(BC/FGvan) | 分子名称: | ACETATE ION, OxyB protein, POTASSIUM ION, ... | 著者 | Brieke, C, Tarnawski, M, Greule, A, Cryle, M.J. | 登録日 | 2018-02-19 | 公開日 | 2018-05-23 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Investigating Cytochrome P450 specificity during glycopeptide antibiotic biosynthesis through a homologue hybridization approach. J. Inorg. Biochem., 185, 2018
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1JPZ
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![BU of 1jpz by Molmil](/molmil-images/mine/1jpz) | Crystal structure of a complex of the heme domain of P450BM-3 with N-Palmitoylglycine | 分子名称: | BIFUNCTIONAL P-450:NADPH-P450 REDUCTASE, N-PALMITOYLGLYCINE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Haines, D.C, Tomchick, D.R, Machius, M, Peterson, J.A. | 登録日 | 2001-08-03 | 公開日 | 2001-11-09 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Pivotal role of water in the mechanism of P450BM-3. Biochemistry, 40, 2001
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1WIY
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![BU of 1wiy by Molmil](/molmil-images/mine/1wiy) | Crystal Structure Analysis of a 6-coordinated Cytochorome P450 from Thermus thermophilus HB8 | 分子名称: | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Kousumi, Y, Nakagawa, N, Kaneko, M, Yamamoto, H, Masui, R, Kuramitsu, S, Ueyama, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2004-05-28 | 公開日 | 2004-11-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure Analysis of Cytochrome P450 from Thermus thermophilus HB8 To be Published
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4UAX
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4KEW
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![BU of 4kew by Molmil](/molmil-images/mine/4kew) | structure of the A82F BM3 heme domain in complex with omeprazole | 分子名称: | 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Leys, D. | 登録日 | 2013-04-26 | 公開日 | 2013-07-10 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Key Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate Bias. J.Biol.Chem., 288, 2013
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2FDU
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![BU of 2fdu by Molmil](/molmil-images/mine/2fdu) | Microsomal P450 2A6 with the inhibitor N,N-Dimethyl(5-(pyridin-3-yl)furan-2-yl)methanamine bound | 分子名称: | Cytochrome P450 2A6, N,N-DIMETHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Yano, J.K, Stout, C.D, Johnson, E.F. | 登録日 | 2005-12-14 | 公開日 | 2006-11-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Synthetic Inhibitors of Cytochrome P-450 2A6: Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization. J.Med.Chem., 49, 2006
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8CKN
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3EJE
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![BU of 3eje by Molmil](/molmil-images/mine/3eje) | |
3EJD
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3EJB
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5WK9
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![BU of 5wk9 by Molmil](/molmil-images/mine/5wk9) | R186AP450cam with CN and camphor | 分子名称: | CAMPHOR, CYANIDE ION, Camphor 5-monooxygenase, ... | 著者 | Poulos, T.L, Batabyal, D. | 登録日 | 2017-07-24 | 公開日 | 2017-09-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.983 Å) | 主引用文献 | Effect of Redox Partner Binding on Cytochrome P450 Conformational Dynamics. J. Am. Chem. Soc., 139, 2017
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5WK7
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![BU of 5wk7 by Molmil](/molmil-images/mine/5wk7) | P450cam mutant R186A | 分子名称: | 5-EXO-HYDROXYCAMPHOR, Camphor 5-monooxygenase, POTASSIUM ION, ... | 著者 | Batabyal, D, Poulos, T.L. | 登録日 | 2017-07-24 | 公開日 | 2017-09-06 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.983 Å) | 主引用文献 | Effect of Redox Partner Binding on Cytochrome P450 Conformational Dynamics. J. Am. Chem. Soc., 139, 2017
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8HGT
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2C7X
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![BU of 2c7x by Molmil](/molmil-images/mine/2c7x) | Crystal structure of narbomycin-bound cytochrome P450 PikC (CYP107L1) | 分子名称: | CYTOCHROME P450 MONOOXYGENASE, NARBOMYCIN, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Sherman, D.H, Li, S, Yermalitskaya, L.V, Kim, Y, Smith, J.A, Waterman, M.R, Podust, L.M. | 登録日 | 2005-11-29 | 公開日 | 2006-07-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | The Structural Basis for Substrate Anchoring, Active Site Selectivity, and Product Formation by P450 Pikc from Streptomyces Venezuelae. J.Biol.Chem., 281, 2006
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6KZS
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![BU of 6kzs by Molmil](/molmil-images/mine/6kzs) | Crystal structure of cytochrome P450mel 107F1 in complex with heme and imidazole | 分子名称: | Cytochrome P-450, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Hou, X.D, Rao, Y.J, Icyishaka, P, Li, C.X, Lou, J.L. | 登録日 | 2019-09-25 | 公開日 | 2020-09-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Crystallization and X-ray analysis of cytochrome P450mel 107F1 with biaryl coupling reactivity To Be Published
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6KZT
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![BU of 6kzt by Molmil](/molmil-images/mine/6kzt) | Crystal structure of cytochrome P450mel 107F1 with biaryl coupling reactivity | 分子名称: | Cytochrome P-450, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Hou, X.D, Rao, Y.J, Icyishaka, P, Li, C.X, Lou, J.L. | 登録日 | 2019-09-25 | 公開日 | 2020-09-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Crystallization and X-ray analysis of cytochrome P450mel 107F1 with biaryl coupling reactivity To Be Published
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6MI0
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![BU of 6mi0 by Molmil](/molmil-images/mine/6mi0) | Crystal structure of the P450 domain of the CYP51-ferredoxin fusion protein from Methylococcus capsulatus, ligand-free state | 分子名称: | Cytochrome P450 51, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Hargrove, T, Wawrzak, Z, Lamb, D.C, Lepesheva, G.I. | 登録日 | 2018-09-18 | 公開日 | 2019-07-10 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Concerning P450 evolution: Structural Analyses Support Bacterial Origin of Sterol 14 alpha-Demethylases. Mol.Biol.Evol., 2020
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4FIA
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![BU of 4fia by Molmil](/molmil-images/mine/4fia) | Crystal Structure of Human CYP46A1 P450 with bicalutamide Bound | 分子名称: | Cholesterol 24-hydroxylase, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Stout, C.D, Pikuleva, I.A, Mast, N. | 登録日 | 2012-06-08 | 公開日 | 2013-01-09 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Binding of a cyano- and fluoro-containing drug bicalutamide to cytochrome P450 46A1: unusual features and spectral response. J.Biol.Chem., 288, 2013
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7SNM
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2VZM
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3ABB
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![BU of 3abb by Molmil](/molmil-images/mine/3abb) | Crystal structure of CYP105D6 | 分子名称: | Cytochrome P450 hydroxylase, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Xu, L.H, Fushinobu, S, Takamatsu, S, Wakagi, T, Ikeda, H, Shoun, H. | 登録日 | 2009-12-04 | 公開日 | 2010-04-07 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Regio- and stereospecificity of filipin hydroxylation sites revealed by crystal structures of cytochrome P450 105P1 and 105D6 from Streptomyces avermitilis J.Biol.Chem., 285, 2010
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1T2B
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![BU of 1t2b by Molmil](/molmil-images/mine/1t2b) | Crystal Structure of cytochrome P450cin complexed with its substrate 1,8-cineole | 分子名称: | 1,3,3-TRIMETHYL-2-OXABICYCLO[2.2.2]OCTANE, P450cin, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Meharenna, Y.T, Li, H, Hawkes, D.B, Pearson, A.G, De Voss, J, Poulos, T.L. | 登録日 | 2004-04-20 | 公開日 | 2005-04-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structure of P450cin in a complex with its substrate, 1,8-cineole, a close structural homologue to D-camphor, the substrate for P450cam Biochemistry, 43, 2004
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5IUZ
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![BU of 5iuz by Molmil](/molmil-images/mine/5iuz) | STRUCTURE OF P450 2B4 F202W MUTANT (CYMAL-5) | 分子名称: | 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B4, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Jang, H.-H, Halpert, J.R, Shah, M.B. | 登録日 | 2016-03-18 | 公開日 | 2016-06-08 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry. Biophys.Chem., 216, 2016
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6L1B
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3ZSN
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![BU of 3zsn by Molmil](/molmil-images/mine/3zsn) | Structure of the mixed-function P450 MycG F286A mutant in complex with mycinamicin IV | 分子名称: | BENZAMIDINE, GLYCEROL, MYCINAMICIN IV, ... | 著者 | Li, S, Kells, P.M, Rutaganira, F.U, Anzai, Y, Kato, F, Sherman, D.H, Podust, L.M. | 登録日 | 2011-06-29 | 公開日 | 2012-05-09 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Substrate Recognition by the Multifunctional Cytochrome P450 Mycg in Mycinamicin Hydroxylation and Epoxidation Reactions. J.Biol.Chem., 287, 2012
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