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1GX5
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Hepatitis C Virus RNA Polymerase in Complex with GTP and Manganese
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
著者Bressanelli, S, Rey, F.A.
登録日2002-03-27
公開日2002-04-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides
J.Virol., 76, 2002
3CJ0
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments
分子名称: 4-[(5-bromopyridin-2-yl)amino]-4-oxobutanoic acid, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CIZ
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with small molecule fragments
分子名称: 2-amino-5-bromobenzoic acid, RNA-directed RNA polymerase, ZINC ION
著者Hendle, j.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ3
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-bromo-2-{[(2R)-2-(2-chlorobenzyl)pyrrolidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ2
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}aniline, NICKEL (II) ION, RNA-directed RNA polymerase
著者Kissinger, c.
登録日2008-03-12
公開日2008-04-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ4
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: 4-[(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)amino]-4-oxobutanoic acid, NICKEL (II) ION, RNA-directed RNA polymerase
著者Antonysamy, s.s.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
3CJ5
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Crystal structure of hepatitis c virus rna-dependent rna polymerase ns5b in complex with optimized small molecule fragments
分子名称: N-(4-bromo-2-{[(3R,5S)-3,5-dimethylpiperidin-1-yl]carbonyl}phenyl)-4-morpholin-4-yl-4-oxobutanamide, RNA-directed RNA polymerase
著者Hendle, j.
登録日2008-03-12
公開日2008-04-15
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Fragment-based discovery of hepatitis C virus NS5b RNA polymerase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
1EF4
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SOLUTION STRUCTURE OF THE ESSENTIAL RNA POLYMERASE SUBUNIT RPB10 FROM METHANOBACTERIUM THERMOAUTOTROPHICUM
分子名称: DNA-DIRECTED RNA POLYMERASE, ZINC ION
著者Mackereth, C.D, Arrowsmith, C.H, Edwards, A.M, Mcintosh, L.P, Northeast Structural Genomics Consortium (NESG)
登録日2000-02-07
公開日2000-06-14
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Zinc-bundle structure of the essential RNA polymerase subunit RPB10 from Methanobacterium thermoautotrophicum.
Proc.Natl.Acad.Sci.USA, 97, 2000
1QUV
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CRYSTAL STRUCTURE OF THE RNA DIRECTED RNA POLYMERASE OF HEPATITIS C VIRUS
分子名称: PROTEIN (RNA-DIRECTED RNA POLYMERASE)
著者Ago, H, Miyano, M, Adachi, T, Habuka, N.
登録日1999-07-04
公開日1999-11-05
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus.
Structure Fold.Des., 7, 1999
3IHQ
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BU of 3ihq by Molmil
Crystal Structure of Reduced C10S Spx in Complex with the Alpha C-terminal Domain of RNA Polymeras
分子名称: DNA-directed RNA polymerase subunit alpha, IMIDAZOLE, Regulatory protein spx
著者Newberry, K.J, Brennan, R.G.
登録日2009-07-30
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Promoter recognition by a complex of Spx and the C-terminal domain of the RNA polymerase alpha subunit.
Plos One, 5, 2010
2RF4
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Crystal structure of the RNA Polymerase I subcomplex A14/43
分子名称: DNA-directed RNA polymerase I subunit RPA4
著者Geiger, S.R, Kuhn, C.D, Cramer, P.
登録日2007-09-28
公開日2008-01-15
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Functional architecture of RNA polymerase I.
Cell(Cambridge,Mass.), 131, 2007
3K4G
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Crystal structure of E. coli RNA polymerase alpha subunit C-terminal domain
分子名称: DNA-directed RNA polymerase subunit alpha, SODIUM ION
著者Lara-Gonzalez, S, Birktoft, J, Lawson, C.L.
登録日2009-10-05
公開日2010-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure of the Escherichia coli RNA polymerase alpha subunit C-terminal domain.
Acta Crystallogr.,Sect.D, 66, 2010
3N4M
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E. coli RNA polymerase alpha subunit C-terminal domain in complex with CAP and DNA
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DI(HYDROXYETHYL)ETHER, ...
著者Lara-Gonzalez, S, Birktoft, J.J, Lawson, C.L.
登録日2010-05-21
公開日2011-05-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.987 Å)
主引用文献The RNA Polymerase alpha Subunit Recognizes the DNA Shape of the Upstream Promoter Element.
Biochemistry, 59, 2020
2PO4
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X-ray crystal structure of polymerase domain of the bacteriophage N4 virion RNA polymerase
分子名称: Virion RNA polymerase
著者Murakami, K.S, Davydova, E.K, Rothman-Denes, L.B.
登録日2007-04-25
公開日2008-04-01
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray crystal structure of polymerase domain of the bacteriophage N4 virion RNA polymerase
Proc.Natl.Acad.Sci.USA, 15, 2008
2MAX
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BU of 2max by Molmil
NMR structure of the RNA polymerase alpha subunit C-terminal domain from Helicobacter pylori
分子名称: DNA-directed RNA polymerase subunit alpha
著者Borin, B.N, Krezel, A.M.
登録日2013-07-21
公開日2014-03-12
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Helicobacter pylori RNA polymerase alpha-subunit C-terminal domain shows features unique to -proteobacteria and binds NikR/DNA complexes.
Protein Sci., 23, 2014
2J7U
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Dengue virus NS5 RNA dependent RNA polymerase domain
分子名称: CHLORIDE ION, MAGNESIUM ION, RNA DEPENDENT RNA POLYMERASE, ...
著者Yap, T.L, Xu, T, Chen, Y.L, Malet, H, Egloff, M.P, Canard, B, Vasudevan, S.G, Lescar, J.
登録日2006-10-17
公開日2007-03-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
1GO3
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Structure of an archeal homolog of the eukaryotic RNA polymerase II RPB4/RPB7 complex
分子名称: DNA-DIRECTED RNA POLYMERASE SUBUNIT E, DNA-DIRECTED RNA POLYMERASE SUBUNIT F
著者Todone, F, Brick, P, Werner, F, Weinzierl, R.O.J, Onesti, S.
登録日2001-10-17
公開日2001-12-07
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of an Archaeal Homolog of the Eukaryotic RNA Polymerase II Rpb4/Rpb7 Complex
Mol.Cell, 8, 2001
4BOC
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Structure of mitochondrial RNA polymerase elongation complex
分子名称: 5'-D(*CP*AP*TP*GP*GP*GP*GP*TP*AP*AP*TP*TP*AP*TP *TP*TP*CP*GP*AP*CP*GP*CP*CP*AP*GP*AP*CP*G)-3', 5'-D(*CP*GP*TP*CP*TP*GP*GP*CP*GP*TP*GP*CP*GP*CP *GP*CP*CP*GP*CP*TP*AP*CP*CP*CP*CP*AP*TP*G)-3', 5'-R(*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP)-3', ...
著者Schwinghammer, K, Cheung, A, Morozov, Y, Agaronyan, K, Temiakov, D, Cramer, P.
登録日2013-05-18
公開日2013-09-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of Human Mitochondrial RNA Polymerase Elongation Complex
Nat.Struct.Mol.Biol., 20, 2013
2LO6
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Structure of Nrd1 CID bound to phosphorylated RNAP II CTD
分子名称: DNA-directed RNA polymerase II subunit RPB1, Protein NRD1
著者Kubicek, K, Cerna, H, Pasulka, J, Holub, P, Hrossova, D, Loehr, F, Hofr, C, Vanacova, S, Stefl, R.
登録日2012-01-17
公開日2012-12-26
実験手法SOLUTION NMR
主引用文献Serine phosphorylation and proline isomerization in RNAP II CTD control recruitment of Nrd1.
Genes Dev., 26, 2012
2M4K
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Solution structure of the delta subunit of RNA polymerase from Bacillus subtilis
分子名称: DNA-directed RNA polymerase subunit delta
著者Papouskova, V, Novacek, J, Kaderavek, P, Zidek, L, Rabatinova, A, Sanderova, H, Krasny, L, Sklenar, V.
登録日2013-02-07
公開日2013-10-09
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Study of the Partially Disordered Full-Length delta Subunit of RNA Polymerase from Bacillus subtilis.
Chembiochem, 14, 2013
2LT1
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Solution NMR structure of the 72-residue N-terminal domain of Myxococcus xanthus CarD
分子名称: CarD protein
著者Jimenez, M.A, Padmanabhan, S.
登録日2012-05-10
公開日2013-11-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure-Function Dissection of Myxococcus xanthus CarD N-Terminal Domain, a Defining Member of the CarD_CdnL_TRCF Family of RNA Polymerase Interacting Proteins.
Plos One, 10
7ZWD
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Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
著者Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
登録日2022-05-19
公開日2022-11-30
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7ZX7
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Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
著者Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
登録日2022-05-20
公開日2022-11-30
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
7ZX8
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Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC)
分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ...
著者Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P.
登録日2022-05-20
公開日2022-12-07
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.
Nat.Struct.Mol.Biol., 29, 2022
2IJF
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Crystal Structure of the Poliovirus RNA-Dependent RNA Polymerase Fidelity Mutant 3Dpol G64S
分子名称: RNA-directed RNA polymerase
著者Marcotte, L.L, Gohara, D.G, Filman, D.J, Hogle, J.M.
登録日2006-09-29
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of poliovirus 3CD: virally-encoded protease and precursor to the RNA-dependent RNA polymerase.
J.Virol., 81, 2007

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