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1LUJ
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Crystal Structure of the Beta-catenin/ICAT Complex
分子名称: Beta-catenin-interacting protein 1, Catenin beta-1
著者Graham, T.A, Clements, W.K, Kimelman, D, Xu, W.
登録日2002-05-22
公開日2002-10-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT.
Mol.Cell, 10, 2002
1XT9
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BU of 1xt9 by Molmil
Crystal Structure of Den1 in complex with Nedd8
分子名称: Neddylin, Sentrin-specific protease 8
著者Reverter, D, Wu, K, Erdene, T.G, Pan, Z.Q, Wilkinson, K.D, Lima, C.D.
登録日2004-10-21
公開日2004-12-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of a Complex between Nedd8 and the Ulp/Senp Protease Family Member Den1.
J.Mol.Biol., 345, 2005
2GRO
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BU of 2gro by Molmil
Crystal Structure of human RanGAP1-Ubc9-N85Q
分子名称: Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I
著者Yunus, A.A, Lima, C.D.
登録日2006-04-24
公開日2006-05-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
2GRN
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BU of 2grn by Molmil
Crystal Structure of human RanGAP1-Ubc9
分子名称: Ran GTPase-activating protein 1, Ubiquitin-conjugating enzyme E2 I
著者Yunus, A.A, Lima, C.D.
登録日2006-04-24
公開日2006-05-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Lysine activation and functional analysis of E2-mediated conjugation in the SUMO pathway.
Nat.Struct.Mol.Biol., 13, 2006
1MD0
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BU of 1md0 by Molmil
CRYSTAL STRUCTURE OF AN INHIBITED FRAGMENT OF Ets-1
分子名称: C-ets-1 protein
著者Garvie, C.W, Pufall, M.A, Graves, B.J, Wolberger, C.
登録日2002-08-06
公開日2002-12-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Analysis of the Autoinhibition of Ets-1 and Its Role in Protein Partnerships
J.Biol.Chem., 277, 2002
8C2E
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BU of 8c2e by Molmil
Structure of 14-3-3 sigma delta C with electrophilic peptide 4IEA-5
分子名称: 14-3-3 protein sigma, ARG-SER-ALA-SEP-CYS-PRO-SER-LEU, CHLORIDE ION, ...
著者van den Oetelaar, M.C.M, Ottmann, C.
登録日2022-12-22
公開日2023-11-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A simple method for developing lysine targeted covalent protein reagents.
Nat Commun, 14, 2023
8C2F
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BU of 8c2f by Molmil
Structure of 14-3-3 sigma delta C with electrophilic peptide 3MHR-5
分子名称: 14-3-3 protein sigma, ARG-ALA-HIS-SEP-CYS-PRO-ALA-SER-LEU-GLN, CHLORIDE ION, ...
著者van den Oetelaar, M.C.M, Ottmann, C.
登録日2022-12-22
公開日2023-11-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A simple method for developing lysine targeted covalent protein reagents.
Nat Commun, 14, 2023
7T3A
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BU of 7t3a by Molmil
GATOR1-RAG-RAGULATOR - Inhibitory Complex
分子名称: GATOR complex protein DEPDC5, GATOR complex protein NPRL2, GATOR complex protein NPRL3, ...
著者Egri, S.B, Shen, K.
登録日2021-12-07
公開日2022-04-06
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.
Mol.Cell, 82, 2022
7T3B
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BU of 7t3b by Molmil
GATOR1-RAG-RAGULATOR - GAP Complex
分子名称: ALUMINUM FLUORIDE, GATOR complex protein DEPDC5, GATOR complex protein NPRL2, ...
著者Egri, S.B, Shen, K.
登録日2021-12-07
公開日2022-04-06
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.
Mol.Cell, 82, 2022
8BZF
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BU of 8bzf by Molmil
FC-J acetonide stabilizer of 14-3-3 and ERalpha
分子名称: 14-3-3 protein sigma, ERalpha peptide, Fusicoccin J-acetonide, ...
著者Visser, E.J, Ottmann, C.
登録日2022-12-14
公開日2023-12-27
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Stabilization of the Estrogen receptor alpha - 14-3-3 interaction as a potential intervention strategy for endocrine resistance in breast cancer
To Be Published
7T3C
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BU of 7t3c by Molmil
GATOR1-RAG-RAGULATOR - Dual Complex
分子名称: ALUMINUM FLUORIDE, GATOR complex protein DEPDC5, GATOR complex protein NPRL2, ...
著者Egri, S.B, Shen, K.
登録日2021-12-07
公開日2022-04-06
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.
Mol.Cell, 82, 2022
6PEO
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BU of 6peo by Molmil
Cryo-EM structure of alpha-synuclein H50Q Narrow Fibril
分子名称: Alpha-synuclein
著者Boyer, D.R, Li, B, Sawaya, M.R, Jiang, L, Eisenberg, D.S.
登録日2019-06-20
公開日2019-11-27
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures of fibrils formed by alpha-synuclein hereditary disease mutant H50Q reveal new polymorphs.
Nat.Struct.Mol.Biol., 26, 2019
8BZC
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BU of 8bzc by Molmil
co-soaked stabilizers for ERa - 14-3-3 interaction (884_AZ244)
分子名称: 14-3-3 protein sigma, 2-(4-chloranylphenoxy)-2-methyl-~{N}-(2-sulfanylethyl)propanamide, 4-[(~{R})-azanyl(oxidanyl)methyl]-7-propan-2-yloxy-1-benzothiophene-2-carboximidamide, ...
著者Visser, E.J, Sijbesma, E, Ottmann, C.
登録日2022-12-14
公開日2023-12-27
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Linked-fragment stabilizers of 14-3-3 protein-protein interactions
To Be Published
8BZM
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BU of 8bzm by Molmil
FOXK1-ELF1-heterodimer bound to DNA
分子名称: DNA, ETS-related transcription factor Elf-1, Forkhead box protein K1, ...
著者Morgunova, E, Popov, A, Yin, Y, Taipale, J.
登録日2022-12-15
公開日2023-12-27
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献FOXK1-ELF1_heterodimer bound to DNA
To Be Published
8C28
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BU of 8c28 by Molmil
14-3-3 in complex with PyrinpS208pS242
分子名称: 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Pyrin
著者Lau, R, Ottmann, C, Hann, M.
登録日2022-12-21
公開日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献14-3-3/Pyrin complex
To Be Published
8C30
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BU of 8c30 by Molmil
Crystal structure of 14-3-3 in complex with PyrinpS242 and a protein/peptide interface fragment
分子名称: 14-3-3 protein sigma, 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, CALCIUM ION, ...
著者Lau, R, Ottmann, C.
登録日2022-12-23
公開日2024-01-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献14-3-3/Pyrin complex
To Be Published
8C2Y
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BU of 8c2y by Molmil
14-3-3 in complex with Pyrinp pS242
分子名称: 14-3-3 protein sigma, Pyrin pS242 peptide
著者Lau, R, Ottmann, C, Hann, M.
登録日2022-12-23
公開日2024-01-10
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献14-3-3/Pyrin complex
To Be Published
8EQG
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BU of 8eqg by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAA(DU)GGAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*DU*AP*AP*AP*TP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*AP*TP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2022-10-07
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EM9
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BU of 8em9 by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAGGAGAAGTAGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*GP*GP*AP*GP*AP*AP*GP*TP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*TP*AP*CP*TP*TP*CP*TP*CP*CP*TP*A)-3'), Transcription factor PU.1
著者Terrell, J.R, Poon, G.M.K.
登録日2022-09-27
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.341 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8COG
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BU of 8cog by Molmil
Human arginylated beta-actin
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ...
著者Pinto, C.S, Bakker, S.E, Suchenko, A, Hussain, H, Hatano, T, Sampath, K, Chinthalapudi, K, Mishima, M, Balasubramanian, M.
登録日2023-02-28
公開日2024-03-06
実験手法ELECTRON MICROSCOPY (3.499 Å)
主引用文献Structure and physiological investigation of human arginylated beta-actin
To Be Published
8EQK
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BU of 8eqk by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAACCGGAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2022-10-07
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EQL
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BU of 8eql by Molmil
Human PU.1 ETS-Domain (165-270) Q226E Mutant Bound to d(AATAACCGGAAGTGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*CP*CP*GP*GP*AP*AP*GP*TP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*AP*CP*TP*TP*CP*CP*GP*GP*TP*TP*AP*T)-3'), SODIUM ION, ...
著者Terrell, J.R, Poon, G.M.K.
登録日2022-10-07
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EJ6
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BU of 8ej6 by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAGAGGAATGGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*GP*AP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*TP*CP*TP*TP*AP*T)-3'), Transcription factor PU.1
著者Terrell, J.R, Poon, G.M.K.
登録日2022-09-16
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
8EKU
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BU of 8eku by Molmil
Human PU.1 ETS-Domain (165-270) Bound to d(AATAAATGGAATGGGG)
分子名称: DNA (5'-D(*AP*AP*TP*AP*AP*AP*TP*GP*GP*AP*AP*TP*GP*GP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*CP*CP*AP*TP*TP*CP*CP*AP*TP*TP*TP*AP*T)-3'), Transcription factor PU.1
著者Terrell, J.R, Poon, G.M.K.
登録日2022-09-22
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献DNA selection by the master transcription factor PU.1.
Cell Rep, 42, 2023
1J7V
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BU of 1j7v by Molmil
HUMAN IL-10 / IL-10R1 COMPLEX
分子名称: INTERLEUKIN-10, INTERLEUKIN-10 RECEPTOR ALPHA CHAIN
著者Josephson, K, Logsdon, N, Walter, M.R.
登録日2001-05-18
公開日2001-09-19
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the IL-10/IL-10R1 complex reveals a shared receptor binding site.
Immunity, 15, 2001

223532

件を2024-08-07に公開中

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