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6QPG
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BU of 6qpg by Molmil
Influenza A virus Polymerase Heterotrimer A/nt/60/1968(H3N2) in complex with Nanobody NB8205
分子名称: Nanobody NB8205, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Fan, H.T, Keown, J.R, Fodor, E, Grimes, J.M.
登録日2019-02-13
公開日2019-09-04
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
6KUR
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BU of 6kur by Molmil
Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B1)
分子名称: 3'-vRNA, 5'-vRNA, Polymerase 3, ...
著者Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
登録日2019-09-02
公開日2019-10-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
6KUK
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BU of 6kuk by Molmil
Structure of influenza D virus polymerase bound to vRNA promoter in mode A conformation (class A1)
分子名称: 3'-vRNA, 5'-vRNA, Polymerase 3, ...
著者Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
登録日2019-09-02
公開日2019-10-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
6KUP
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BU of 6kup by Molmil
Structure of influenza D virus polymerase bound to vRNA promoter in Mode A conformation(Class A2)
分子名称: 3'-vRNA, 5'-vRNA, Polymerase 3, ...
著者Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
登録日2019-09-02
公開日2019-10-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
6KUV
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BU of 6kuv by Molmil
Structure of influenza D virus polymerase bound to cRNA promoter in class 2
分子名称: 3'-cRNA, 5'-cRNA, Polymerase 3, ...
著者Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
登録日2019-09-02
公開日2019-10-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
6KUT
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BU of 6kut by Molmil
Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B2)
分子名称: 3'-vRNA, 5'-vRNA, Polymerase 3, ...
著者Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
登録日2019-09-02
公開日2019-10-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
8R60
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BU of 8r60 by Molmil
1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide
分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2023-11-19
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide
To Be Published
8R65
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BU of 8r65 by Molmil
1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains
分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ...
著者Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M.
登録日2023-11-20
公開日2024-03-27
実験手法ELECTRON MICROSCOPY (4.23 Å)
主引用文献1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains
To Be Published
6KUU
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BU of 6kuu by Molmil
Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B3)
分子名称: 3'-vRNA, 5'-vRNA, Polymerase 3, ...
著者Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
登録日2019-09-02
公開日2019-12-11
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B3)
To Be Published
7X6V
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BU of 7x6v by Molmil
lymphocytic choriomeningitis virus polymerase- Matrix Z Protein Complex (LCMV L-Z Complex)
分子名称: MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ...
著者Liu, L, Lou, Z.
登録日2022-03-08
公開日2023-09-13
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure basis for allosteric regulation of lymphocytic choriomeningitis virus polymerase function by Z matrix protein.
Protein Cell, 14, 2023
7Y38
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BU of 7y38 by Molmil
Molecular architecture of the chikungunya virus replication complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Protease nsP2, ...
著者Tan, Y.B, Luo, D.
登録日2022-06-10
公開日2022-12-14
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Molecular architecture of the Chikungunya virus replication complex.
Sci Adv, 8, 2022
5MSG
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BU of 5msg by Molmil
Influenza B polymerase bound to vRNA promoter and capped RNA primer
分子名称: PHOSPHATE ION, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Cusack, S, Guilligay, D.
登録日2017-01-04
公開日2017-02-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献An in vitro fluorescence based study of initiation of RNA synthesis by influenza B polymerase.
Nucleic Acids Res., 45, 2017
4V0R
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BU of 4v0r by Molmil
DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH GTP AND SAH
分子名称: FORMIC ACID, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Zhao, Y, Soh, S, Zheng, J, Phoo, W.W, Swaminathan, K, Cornvik, T.C, Lim, S.P, Shi, P.-Y, Lescar, J, Vasudevan, S.G, Luo, D.
登録日2014-09-18
公開日2015-01-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication.
Plos Pathog., 11, 2015
7YER
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BU of 7yer by Molmil
The structure of EBOV L-VP35 complex
分子名称: Polymerase cofactor VP35, RNA-directed RNA polymerase L, ZINC ION
著者Shi, Y, Yuan, B, Peng, Q.
登録日2022-07-06
公開日2022-10-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structure of the Ebola virus polymerase complex.
Nature, 610, 2022
7YET
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BU of 7yet by Molmil
The structure of EBOV L-VP35 in complex with suramin
分子名称: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Polymerase cofactor VP35, RNA-directed RNA polymerase L
著者Shi, Y, Yuan, B, Peng, Q.
登録日2022-07-06
公開日2022-10-05
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure of the Ebola virus polymerase complex.
Nature, 610, 2022
6RR7
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BU of 6rr7 by Molmil
Influenza A virus (A/NT/60/1968) polymerase Heterotrimer bound to 3'5' vRNA promoter and capped RNA primer
分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(M7G))-R(P*AP*AP*UP*CP*U)-3'), ...
著者Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M.
登録日2019-05-17
公開日2019-09-04
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.01 Å)
主引用文献Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
6QX3
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BU of 6qx3 by Molmil
Influenza A virus (A/NT/60/1968) polymerase Hetermotrimer in complex with 3'5' cRNA promoter and Nb8205
分子名称: Nb8205, Polymerase acidic protein, Polymerase basic protein 2, ...
著者Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M.
登録日2019-03-07
公開日2019-09-04
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.79 Å)
主引用文献Structures of influenza A virus RNA polymerase offer insight into viral genome replication.
Nature, 573, 2019
2FQM
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BU of 2fqm by Molmil
Crystal structure of the oligomerization domain of the phosphoprotein of vesicular stomatitis virus
分子名称: Phosphoprotein
著者Ding, H, Green, T.J, Lu, S, Luo, M.
登録日2006-01-18
公開日2006-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the oligomerization domain of the phosphoprotein of vesicular stomatitis virus
J.Virol., 80, 2006
4W9S
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BU of 4w9s by Molmil
2-(4-(1H-tetrazol-5-yl)phenyl)-5-hydroxypyrimidin-4(3H)-one bound to influenza 2009 H1N1 endonuclease
分子名称: 5-hydroxy-2-[4-(1H-tetrazol-5-yl)phenyl]pyrimidin-4(3H)-one, MANGANESE (II) ION, Polymerase acidic protein, ...
著者Bauman, J.D, Patel, D, Das, K, Arnold, E.
登録日2014-08-27
公開日2014-10-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Phenyl Substituted 4-Hydroxypyridazin-3(2H)-ones and 5-Hydroxypyrimidin-4(3H)-ones: Inhibitors of Influenza A Endonuclease.
J.Med.Chem., 57, 2014
6T0W
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BU of 6t0w by Molmil
Human Influenza B polymerase recycling complex
分子名称: Polymerase PB2, Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, ...
著者Wandzik, J.M, Kouba, T, Karuppasamy, M, Cusack, S.
登録日2019-10-03
公開日2020-04-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 181, 2020
5K5M
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BU of 5k5m by Molmil
Co-Crystal Structure of Dengue Virus Serotype 2 RNA Dependent RNA Polymerase with Compound 27
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-2,4-dimethoxy-N-[(3-methoxyphenyl)sulfonyl]benzamide, RNA Dependent RNA Polymerase, ...
著者Arora, R, Benson, T.E.
登録日2016-05-23
公開日2016-08-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling.
Plos Pathog., 12, 2016
6SZV
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BU of 6szv by Molmil
Bat Influenza A polymerase elongation complex with incoming UTP analogue (core + endonuclease only)
分子名称: 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ...
著者Wandzik, J.M, Kouba, T, Cusack, S.
登録日2019-10-02
公開日2020-04-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 181, 2020
6T0V
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BU of 6t0v by Molmil
Bat Influenza A polymerase elongation complex with incoming UTP analogue (complete polymerase)
分子名称: 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ...
著者Wandzik, J.M, Kouba, T, Cusack, S.
登録日2019-10-03
公開日2020-04-15
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Cell, 181, 2020
6KV5
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BU of 6kv5 by Molmil
Structure of influenza D virus apo polymerase
分子名称: Polymerase 3, Polymerase PB2, RNA-directed RNA polymerase catalytic subunit
著者Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y.
登録日2019-09-03
公開日2019-10-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural insight into RNA synthesis by influenza D polymerase.
Nat Microbiol, 4, 2019
6XZG
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BU of 6xzg by Molmil
Influenza C virus polymerase in complex with chicken ANP32A - Subclass 3
分子名称: Influenza viral RNA (vRNA) promoter 47mer, LRRcap domain-containing protein, Polymerase acidic protein, ...
著者Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E.
登録日2020-02-04
公開日2020-11-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Host ANP32A mediates the assembly of the influenza virus replicase.
Nature, 587, 2020

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件を2024-07-10に公開中

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