6QPG
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![BU of 6qpg by Molmil](/molmil-images/mine/6qpg) | Influenza A virus Polymerase Heterotrimer A/nt/60/1968(H3N2) in complex with Nanobody NB8205 | 分子名称: | Nanobody NB8205, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Fan, H.T, Keown, J.R, Fodor, E, Grimes, J.M. | 登録日 | 2019-02-13 | 公開日 | 2019-09-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | 主引用文献 | Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
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6KUR
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![BU of 6kur by Molmil](/molmil-images/mine/6kur) | Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B1) | 分子名称: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | 登録日 | 2019-09-02 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
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6KUK
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![BU of 6kuk by Molmil](/molmil-images/mine/6kuk) | Structure of influenza D virus polymerase bound to vRNA promoter in mode A conformation (class A1) | 分子名称: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | 登録日 | 2019-09-02 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
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6KUP
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![BU of 6kup by Molmil](/molmil-images/mine/6kup) | Structure of influenza D virus polymerase bound to vRNA promoter in Mode A conformation(Class A2) | 分子名称: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | 登録日 | 2019-09-02 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
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6KUV
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![BU of 6kuv by Molmil](/molmil-images/mine/6kuv) | Structure of influenza D virus polymerase bound to cRNA promoter in class 2 | 分子名称: | 3'-cRNA, 5'-cRNA, Polymerase 3, ... | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | 登録日 | 2019-09-02 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
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6KUT
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![BU of 6kut by Molmil](/molmil-images/mine/6kut) | Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B2) | 分子名称: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | 登録日 | 2019-09-02 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
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8R60
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![BU of 8r60 by Molmil](/molmil-images/mine/8r60) | 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2023-11-19 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.23 Å) | 主引用文献 | 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide To Be Published
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8R65
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![BU of 8r65 by Molmil](/molmil-images/mine/8r65) | 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(P*AP*GP*UP*AP*GP*AP*AP*AP*CP*AP*AP*GP*GP*CP*C)-3'), ... | 著者 | Keown, J.R, Carrique, L, Fodor, E, Grimes, J.M. | 登録日 | 2023-11-20 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.23 Å) | 主引用文献 | 1918 H1N1 Viral polymerase heterotrimer in complex with 4 repeat serine-5 phosphorylated PolII peptide with ordered PB2 C-terminal domains To Be Published
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6KUU
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![BU of 6kuu by Molmil](/molmil-images/mine/6kuu) | Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B3) | 分子名称: | 3'-vRNA, 5'-vRNA, Polymerase 3, ... | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | 登録日 | 2019-09-02 | 公開日 | 2019-12-11 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure of influenza D virus polymerase bound to vRNA promoter in Mode B conformation (Class B3) To Be Published
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7X6V
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![BU of 7x6v by Molmil](/molmil-images/mine/7x6v) | |
7Y38
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![BU of 7y38 by Molmil](/molmil-images/mine/7y38) | |
5MSG
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![BU of 5msg by Molmil](/molmil-images/mine/5msg) | |
4V0R
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![BU of 4v0r by Molmil](/molmil-images/mine/4v0r) | DENGUE VIRUS FULL LENGTH NS5 COMPLEXED WITH GTP AND SAH | 分子名称: | FORMIC ACID, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Zhao, Y, Soh, S, Zheng, J, Phoo, W.W, Swaminathan, K, Cornvik, T.C, Lim, S.P, Shi, P.-Y, Lescar, J, Vasudevan, S.G, Luo, D. | 登録日 | 2014-09-18 | 公開日 | 2015-01-28 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A Crystal Structure of the Dengue Virus Ns5 Protein Reveals a Novel Inter-Domain Interface Essential for Protein Flexibility and Virus Replication. Plos Pathog., 11, 2015
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7YER
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![BU of 7yer by Molmil](/molmil-images/mine/7yer) | |
7YET
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![BU of 7yet by Molmil](/molmil-images/mine/7yet) | The structure of EBOV L-VP35 in complex with suramin | 分子名称: | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Polymerase cofactor VP35, RNA-directed RNA polymerase L | 著者 | Shi, Y, Yuan, B, Peng, Q. | 登録日 | 2022-07-06 | 公開日 | 2022-10-05 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of the Ebola virus polymerase complex. Nature, 610, 2022
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6RR7
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![BU of 6rr7 by Molmil](/molmil-images/mine/6rr7) | Influenza A virus (A/NT/60/1968) polymerase Heterotrimer bound to 3'5' vRNA promoter and capped RNA primer | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-D(*(M7G))-R(P*AP*AP*UP*CP*U)-3'), ... | 著者 | Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | 登録日 | 2019-05-17 | 公開日 | 2019-09-04 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
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6QX3
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![BU of 6qx3 by Molmil](/molmil-images/mine/6qx3) | Influenza A virus (A/NT/60/1968) polymerase Hetermotrimer in complex with 3'5' cRNA promoter and Nb8205 | 分子名称: | Nb8205, Polymerase acidic protein, Polymerase basic protein 2, ... | 著者 | Carrique, L, Keown, J.R, Fan, H, Fodor, E, Grimes, J.M. | 登録日 | 2019-03-07 | 公開日 | 2019-09-04 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | 主引用文献 | Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
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2FQM
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![BU of 2fqm by Molmil](/molmil-images/mine/2fqm) | |
4W9S
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![BU of 4w9s by Molmil](/molmil-images/mine/4w9s) | 2-(4-(1H-tetrazol-5-yl)phenyl)-5-hydroxypyrimidin-4(3H)-one bound to influenza 2009 H1N1 endonuclease | 分子名称: | 5-hydroxy-2-[4-(1H-tetrazol-5-yl)phenyl]pyrimidin-4(3H)-one, MANGANESE (II) ION, Polymerase acidic protein, ... | 著者 | Bauman, J.D, Patel, D, Das, K, Arnold, E. | 登録日 | 2014-08-27 | 公開日 | 2014-10-01 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Phenyl Substituted 4-Hydroxypyridazin-3(2H)-ones and 5-Hydroxypyrimidin-4(3H)-ones: Inhibitors of Influenza A Endonuclease. J.Med.Chem., 57, 2014
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6T0W
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![BU of 6t0w by Molmil](/molmil-images/mine/6t0w) | Human Influenza B polymerase recycling complex | 分子名称: | Polymerase PB2, Polymerase acidic protein, RNA-directed RNA polymerase catalytic subunit, ... | 著者 | Wandzik, J.M, Kouba, T, Karuppasamy, M, Cusack, S. | 登録日 | 2019-10-03 | 公開日 | 2020-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
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5K5M
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![BU of 5k5m by Molmil](/molmil-images/mine/5k5m) | |
6SZV
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![BU of 6szv by Molmil](/molmil-images/mine/6szv) | Bat Influenza A polymerase elongation complex with incoming UTP analogue (core + endonuclease only) | 分子名称: | 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... | 著者 | Wandzik, J.M, Kouba, T, Cusack, S. | 登録日 | 2019-10-02 | 公開日 | 2020-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
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6T0V
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![BU of 6t0v by Molmil](/molmil-images/mine/6t0v) | Bat Influenza A polymerase elongation complex with incoming UTP analogue (complete polymerase) | 分子名称: | 3' vRNA, 5' vRNA, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, ... | 著者 | Wandzik, J.M, Kouba, T, Cusack, S. | 登録日 | 2019-10-03 | 公開日 | 2020-04-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase. Cell, 181, 2020
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6KV5
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![BU of 6kv5 by Molmil](/molmil-images/mine/6kv5) | Structure of influenza D virus apo polymerase | 分子名称: | Polymerase 3, Polymerase PB2, RNA-directed RNA polymerase catalytic subunit | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | 登録日 | 2019-09-03 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural insight into RNA synthesis by influenza D polymerase. Nat Microbiol, 4, 2019
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6XZG
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![BU of 6xzg by Molmil](/molmil-images/mine/6xzg) | Influenza C virus polymerase in complex with chicken ANP32A - Subclass 3 | 分子名称: | Influenza viral RNA (vRNA) promoter 47mer, LRRcap domain-containing protein, Polymerase acidic protein, ... | 著者 | Carrique, L, Keown, J.R, Fan, H, Grimes, J.M, Fodor, E. | 登録日 | 2020-02-04 | 公開日 | 2020-11-25 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Host ANP32A mediates the assembly of the influenza virus replicase. Nature, 587, 2020
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