PDB: 2940 件ウェブページステータス検索Chemie searchBIRD

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4G9F	Crystal Structure of C12C TCR-HLAB2705-KK10-L6M 分子名称: Beta-2-microglobulin, Gag protein, HLA class I histocompatibility antigen, ... 著者 Gras, S, Wilmann, P.G, Rossjohn, J. 登録日 2012-07-23 公開日 2013-03-20 最終更新日 2020-04-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells. Immunity, 38, 2013
6DDR	Crystal Structure Analysis of the Epitope of an Anti-MICA Antibody 分子名称: Anti-MICA Fab fragment heavy chain clone 13A9, Anti-MICA Fab fragment light chain clone 13A9, GLYCEROL, ... 著者 Matsumoto, M.L. 登録日 2018-05-10 公開日 2018-10-24 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies. MAbs, 11, 2019
8Y74	Crystal structure of 9-mer peptide from H9N2 avian influenza virus in complex with BF2*0201 分子名称: Beta-2-microglobulin, MHC class I alpha chain 2, Polymerase basic protein 2 著者 Jia, Y.S, Ma, M.L. 登録日 2024-02-03 公開日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Revealing novel and conservative T-cell epitopes with MHC B2 restriction on H9N2 avian influenza virus (AIV). J.Biol.Chem., 300, 2024
1R3J	potassium channel KcsA-Fab complex in high concentration of Tl+ 分子名称: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... 著者 Zhou, Y, MacKinnon, R. 登録日 2003-10-02 公開日 2003-11-25 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates J.Mol.Biol., 333, 2003
6DCV	Crystal structure of human anti-tau antibody CBTAU-27.1 分子名称: GLYCEROL, Light chain of CBTAU27.1 Fab, heavy chain of CBTAU-27.1 Fab 著者 Zhu, X, Zhang, H, Wilson, I.A. 登録日 2018-05-08 公開日 2018-06-06 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities. Acta Neuropathol Commun, 6, 2018
1RJY	Mhc Class I Natural Mutant H-2Kbm8 Heavy Chain Complexed With beta-2 Microglobulin and Herpes Simplex Virus Glycoprotein B Peptide 分子名称: Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ... 著者 Miley, M.J, Messaoudi, I, Nikolich-Zugich, J, Fremont, D.H. 登録日 2003-11-20 公開日 2004-12-14 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis for the Restoration of TCR Recognition of an MHC Allelic Variant by Peptide Secondary Anchor Substitution J.Exp.Med., 200, 2004
6P4B	HyHEL10 fab variant HyHEL10-4x (heavy chain mutations L4F, Y33H, S56N, and Y58F) bound to hen egg lysozyme variant HEL2x-flex (mutations R21Q, R73E, C76S, and C94S) 分子名称: CHLORIDE ION, HyHEL10 Fab heavy chain, HyHEL10 Fab light chain, ... 著者 Langley, D.B, Christ, D. 登録日 2019-05-27 公開日 2020-05-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens. Proc.Natl.Acad.Sci.USA, 117, 2020
1NDG	Crystal structure of Fab fragment of antibody HyHEL-8 complexed with its antigen lysozyme 分子名称: ACETIC ACID, Lysozyme C, antibody kappa light chain, ... 著者 Mariuzza, R.A, Li, Y, Li, H, Yang, F, Smith-Gill, S.J. 登録日 2002-12-09 公開日 2003-06-03 最終更新日 2021-10-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray snapshots of the maturation of an antibody response to a protein antigen Nat.Struct.Biol., 10, 2003
3VFM	crystal structure of HLA B*3508 LPEP155A, HLA mutant Ala155 分子名称: Beta-2-microglobulin, LPEP peptide from EBV, LPEPLPQGQLTAY, ... 著者 Liu, Y.C, Rossjohn, J, Gras, S. 登録日 2012-01-10 公開日 2012-03-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule. J.Biol.Chem., 287, 2012
2AKR	Structural basis of sulfatide presentation by mouse CD1d 分子名称: (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Zajonc, D.M, Halder, R, Wu, D, Maricic, I, Roy, K, Wong, C.-H, Kumar, V, Wilson, I.A. 登録日 2005-08-03 公開日 2005-12-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity J.Exp.Med., 202, 2005
1FNE	HISTOCOMPATIBILITY ANTIGEN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (MHC CLASS II I-EK, ALPHA CHAIN), ... 著者 Miley, M.J, Nelson, C.A, Fremont, D.H. 登録日 2000-08-21 公開日 2001-03-07 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional consequences of altering a peptide MHC anchor residue. J.Immunol., 166, 2001
1T1Z	Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-6A 分子名称: Beta-2-microglobulin, GAG PEPTIDE, HLA class I histocompatibility antigen, ... 著者 Martinez-Hackert, E, Anikeeva, N, Kalams, S.A, Walker, B.D, Hendrickson, W.A, Sykulev, Y. 登録日 2004-04-19 公開日 2005-09-06 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J.Biol.Chem., 281, 2006
6U3M	DQ2-P.fluor-alpha1a 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha1a peptide, ... 著者 Petersen, J, Rossjohn, J. 登録日 2019-08-22 公開日 2019-12-18 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease. Nat.Struct.Mol.Biol., 27, 2020
4WI2	Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc (wild-type) 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region 著者 Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. 登録日 2014-09-25 公開日 2015-09-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice To Be Published
4WI7	Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation H435A 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region 著者 Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. 登録日 2014-09-25 公開日 2015-09-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice To Be Published
7SIH	Crystal Structure of HLA B*3503 in complex with NPDIVIYQY, an 9-mer epitope from HIV-I 分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... 著者 Gras, S, Lobos, C.A, Chatzileontiadou, D.S.M. 登録日 2021-10-14 公開日 2022-11-23 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular insights into the HLA-B35 molecules' classification associated with HIV control. Immunol.Cell.Biol., 102, 2024
7SIS	SARS-CoV-2 Spike-derived peptide S976-984 (VLNDILSRL) presented by HLA-A*02:01 分子名称: ACETATE ION, Beta-2-microglobulin, CADMIUM ION, ... 著者 Szeto, C, Gras, S. 登録日 2021-10-14 公開日 2022-11-23 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific Curr Res Struct Biol, 2024
7KGT	Crystal Structure of HLA-A*0201 in complex with SARS-CoV-2 N226-234 分子名称: ACETATE ION, Beta-2-microglobulin, CADMIUM ION, ... 著者 Szeto, C, Chatzileontiadou, D.S.M, Riboldi-Tunnicliffe, A, Gras, S. 登録日 2020-10-18 公開日 2021-01-20 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The presentation of SARS-CoV-2 peptides by the common HLA-A*02:01 molecule. Iscience, 24, 2021
6ULK	Molecular basis for tumor infiltrating TCR recognition of hotspot KRAS-G12D mutation 分子名称: Beta-2-microglobulin, GLY-ALA-ASP-GLY-VAL-GLY-LYS-SER-ALA-LEU, HLA class I antigen 著者 Sun, P.D, Sim, M.J.W. 登録日 2019-10-08 公開日 2020-05-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 High-affinity oligoclonal TCRs define effective adoptive T cell therapy targeting mutant KRAS-G12D. Proc.Natl.Acad.Sci.USA, 117, 2020
6UJ7	Crystal structure of HLA-B*07:02 with R140Q mutant IDH2 peptide 分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ... 著者 Miller, M.S, Thirawatananond, P, Gabelli, S.B. 登録日 2019-10-02 公開日 2021-05-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens. Nat Commun, 12, 2021
1WBX	CRYSTAL STRUCTURES OF MURINE MHC CLASS I H-2 Db AND Kb MOLECULES IN COMPLEX WITH CTL EPITOPES FROM INFLUENZA A VIRUS: IMPLICATIONS FOR TCR REPERTOIRE SELECTION AND IMMUNODOMINANCE 分子名称: BETA-2MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, ... 著者 Meijers, R, Lai, C, Yang, Y, Liu, J, Zhong, W, Wang, J, Reinherz, E.L. 登録日 2004-11-05 公開日 2005-01-19 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance J.Mol.Biol., 345, 2005
3O3B	Human Class I MHC HLA-A2 in complex with the Peptidomimetic ELA-1.1 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Borbulevych, O.Y, Baker, B.M. 登録日 2010-07-23 公開日 2010-12-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structures of HLA-A*0201 complexed with Melan-A/MART-1(26(27L)-35) peptidomimetics reveal conformational heterogeneity and highlight degeneracy of T cell recognition. J.Med.Chem., 53, 2010
6ATF	HLA-DRB1*1402 in complex with Vimentin59-71 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Scally, S.W, Ting, Y.T, Rossjohn, J. 登録日 2017-08-29 公開日 2017-09-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis. Ann. Rheum. Dis., 76, 2017
5U6Q	Structure of human MR1-3-F-SA in complex with human MAIT A-F7 TCR 分子名称: 3-methanoyl-2-oxidanyl-benzoic acid, ACETATE ION, Beta-2-microglobulin, ... 著者 Keller, A.N, Rossjohn, J. 登録日 2016-12-08 公開日 2017-02-08 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells. Nat. Immunol., 18, 2017
1ORS	X-ray structure of the KvAP potassium channel voltage sensor in complex with an Fab 分子名称: 33H1 Fab heavy chain, 33H1 Fab light chain, potassium channel 著者 Jiang, Y, Lee, A, Chen, J, Ruta, V, Cadene, M, Chait, B.T, MacKinnon, R. 登録日 2003-03-14 公開日 2003-05-06 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 X-ray structure of a voltage-dependent K+ channel Nature, 423, 2003

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