4G9F
| Crystal Structure of C12C TCR-HLAB2705-KK10-L6M | 分子名称: | Beta-2-microglobulin, Gag protein, HLA class I histocompatibility antigen, ... | 著者 | Gras, S, Wilmann, P.G, Rossjohn, J. | 登録日 | 2012-07-23 | 公開日 | 2013-03-20 | 最終更新日 | 2020-04-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells. Immunity, 38, 2013
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6DDR
| Crystal Structure Analysis of the Epitope of an Anti-MICA Antibody | 分子名称: | Anti-MICA Fab fragment heavy chain clone 13A9, Anti-MICA Fab fragment light chain clone 13A9, GLYCEROL, ... | 著者 | Matsumoto, M.L. | 登録日 | 2018-05-10 | 公開日 | 2018-10-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies. MAbs, 11, 2019
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8Y74
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1R3J
| potassium channel KcsA-Fab complex in high concentration of Tl+ | 分子名称: | Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, DIACYL GLYCEROL, ... | 著者 | Zhou, Y, MacKinnon, R. | 登録日 | 2003-10-02 | 公開日 | 2003-11-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The occupancy of ions in the K+ selectivity filter: Charge balance and coupling of ion binding to a protein conformational change underlie high conduction rates J.Mol.Biol., 333, 2003
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6DCV
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1RJY
| Mhc Class I Natural Mutant H-2Kbm8 Heavy Chain Complexed With beta-2 Microglobulin and Herpes Simplex Virus Glycoprotein B Peptide | 分子名称: | Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ... | 著者 | Miley, M.J, Messaoudi, I, Nikolich-Zugich, J, Fremont, D.H. | 登録日 | 2003-11-20 | 公開日 | 2004-12-14 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis for the Restoration of TCR Recognition of an MHC Allelic Variant by Peptide Secondary Anchor Substitution J.Exp.Med., 200, 2004
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6P4B
| HyHEL10 fab variant HyHEL10-4x (heavy chain mutations L4F, Y33H, S56N, and Y58F) bound to hen egg lysozyme variant HEL2x-flex (mutations R21Q, R73E, C76S, and C94S) | 分子名称: | CHLORIDE ION, HyHEL10 Fab heavy chain, HyHEL10 Fab light chain, ... | 著者 | Langley, D.B, Christ, D. | 登録日 | 2019-05-27 | 公開日 | 2020-05-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens. Proc.Natl.Acad.Sci.USA, 117, 2020
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1NDG
| Crystal structure of Fab fragment of antibody HyHEL-8 complexed with its antigen lysozyme | 分子名称: | ACETIC ACID, Lysozyme C, antibody kappa light chain, ... | 著者 | Mariuzza, R.A, Li, Y, Li, H, Yang, F, Smith-Gill, S.J. | 登録日 | 2002-12-09 | 公開日 | 2003-06-03 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | X-ray snapshots of the maturation of an antibody response to a protein antigen Nat.Struct.Biol., 10, 2003
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3VFM
| crystal structure of HLA B*3508 LPEP155A, HLA mutant Ala155 | 分子名称: | Beta-2-microglobulin, LPEP peptide from EBV, LPEPLPQGQLTAY, ... | 著者 | Liu, Y.C, Rossjohn, J, Gras, S. | 登録日 | 2012-01-10 | 公開日 | 2012-03-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule. J.Biol.Chem., 287, 2012
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2AKR
| Structural basis of sulfatide presentation by mouse CD1d | 分子名称: | (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Zajonc, D.M, Halder, R, Wu, D, Maricic, I, Roy, K, Wong, C.-H, Kumar, V, Wilson, I.A. | 登録日 | 2005-08-03 | 公開日 | 2005-12-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity J.Exp.Med., 202, 2005
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1FNE
| HISTOCOMPATIBILITY ANTIGEN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (MHC CLASS II I-EK, ALPHA CHAIN), ... | 著者 | Miley, M.J, Nelson, C.A, Fremont, D.H. | 登録日 | 2000-08-21 | 公開日 | 2001-03-07 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and functional consequences of altering a peptide MHC anchor residue. J.Immunol., 166, 2001
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1T1Z
| Structural basis for degenerate recognition of HIV peptide variants by cytotoxic lymphocyte, variant SL9-6A | 分子名称: | Beta-2-microglobulin, GAG PEPTIDE, HLA class I histocompatibility antigen, ... | 著者 | Martinez-Hackert, E, Anikeeva, N, Kalams, S.A, Walker, B.D, Hendrickson, W.A, Sykulev, Y. | 登録日 | 2004-04-19 | 公開日 | 2005-09-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Basis for Degenerate Recognition of Natural HIV Peptide Variants by Cytotoxic Lymphocytes. J.Biol.Chem., 281, 2006
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6U3M
| DQ2-P.fluor-alpha1a | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha1a peptide, ... | 著者 | Petersen, J, Rossjohn, J. | 登録日 | 2019-08-22 | 公開日 | 2019-12-18 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease. Nat.Struct.Mol.Biol., 27, 2020
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4WI2
| Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc (wild-type) | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | 著者 | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | 登録日 | 2014-09-25 | 公開日 | 2015-09-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice To Be Published
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4WI7
| Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation H435A | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region | 著者 | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | 登録日 | 2014-09-25 | 公開日 | 2015-09-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice To Be Published
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7SIH
| Crystal Structure of HLA B*3503 in complex with NPDIVIYQY, an 9-mer epitope from HIV-I | 分子名称: | Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ... | 著者 | Gras, S, Lobos, C.A, Chatzileontiadou, D.S.M. | 登録日 | 2021-10-14 | 公開日 | 2022-11-23 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular insights into the HLA-B35 molecules' classification associated with HIV control. Immunol.Cell.Biol., 102, 2024
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7SIS
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7KGT
| Crystal Structure of HLA-A*0201 in complex with SARS-CoV-2 N226-234 | 分子名称: | ACETATE ION, Beta-2-microglobulin, CADMIUM ION, ... | 著者 | Szeto, C, Chatzileontiadou, D.S.M, Riboldi-Tunnicliffe, A, Gras, S. | 登録日 | 2020-10-18 | 公開日 | 2021-01-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The presentation of SARS-CoV-2 peptides by the common HLA-A*02:01 molecule. Iscience, 24, 2021
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6ULK
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6UJ7
| Crystal structure of HLA-B*07:02 with R140Q mutant IDH2 peptide | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ... | 著者 | Miller, M.S, Thirawatananond, P, Gabelli, S.B. | 登録日 | 2019-10-02 | 公開日 | 2021-05-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural engineering of chimeric antigen receptors targeting HLA-restricted neoantigens. Nat Commun, 12, 2021
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1WBX
| CRYSTAL STRUCTURES OF MURINE MHC CLASS I H-2 Db AND Kb MOLECULES IN COMPLEX WITH CTL EPITOPES FROM INFLUENZA A VIRUS: IMPLICATIONS FOR TCR REPERTOIRE SELECTION AND IMMUNODOMINANCE | 分子名称: | BETA-2MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B ALPHA CHAIN, ... | 著者 | Meijers, R, Lai, C, Yang, Y, Liu, J, Zhong, W, Wang, J, Reinherz, E.L. | 登録日 | 2004-11-05 | 公開日 | 2005-01-19 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structures of Murine Mhc Class I H-2 D(B) and K(B) Molecules in Complex with Ctl Epitopes from Influenza a Virus: Implications for Tcr Repertoire Selection and Immunodominance J.Mol.Biol., 345, 2005
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3O3B
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6ATF
| HLA-DRB1*1402 in complex with Vimentin59-71 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Scally, S.W, Ting, Y.T, Rossjohn, J. | 登録日 | 2017-08-29 | 公開日 | 2017-09-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis. Ann. Rheum. Dis., 76, 2017
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5U6Q
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1ORS
| X-ray structure of the KvAP potassium channel voltage sensor in complex with an Fab | 分子名称: | 33H1 Fab heavy chain, 33H1 Fab light chain, potassium channel | 著者 | Jiang, Y, Lee, A, Chen, J, Ruta, V, Cadene, M, Chait, B.T, MacKinnon, R. | 登録日 | 2003-03-14 | 公開日 | 2003-05-06 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | X-ray structure of a voltage-dependent K+ channel Nature, 423, 2003
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