PDB: 1371 件ウェブページステータス検索Chemie searchBIRD

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5Y5J	Time-resolved SFX structure of cytochrome P450nor: dark-2 data in the presence of NADH (resting state) 分子名称: GLYCEROL, NADP nitrous oxide-forming nitric oxide reductase, PROTOPORPHYRIN IX CONTAINING FE 著者 Tosha, T, Nomura, T, Nishida, T, Saeki, N, Okubayashi, K, Yamagiwa, R, Sugahara, M, Nakane, T, Yamashita, K, Hirata, K, Ueno, G, Kimura, T, Hisano, T, Muramoto, K, Sawai, H, Takeda, H, Mizohata, E, Yamashita, A, Kanematsu, Y, Takano, Y, Nango, E, Tanaka, R, Nureki, O, Ikemoto, Y, Murakami, H, Owada, S, Tono, K, Yabashi, M, Yamamoto, M, Ago, H, Iwata, S, Sugimoto, H, Shiro, Y, Kubo, M. 登録日 2017-08-09 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate. Nat Commun, 8, 2017
5YM3	CYP76AH1-4pi from salvia miltiorrhiza 分子名称: 4-PHENYL-1H-IMIDAZOLE, Ferruginol synthase, MANGANESE (II) ION, ... 著者 Chang, Z. 登録日 2017-10-20 公開日 2018-10-24 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.601 Å) 主引用文献 Crystal structure of CYP76AH1 in 4-PI-bound state from Salvia miltiorrhiza. Biochem.Biophys.Res.Commun., 511, 2019
5Y5G	Structure of cytochrome P450nor in NO-bound state: damaged by high-dose (5.7 MGy) X-ray 分子名称: GLYCEROL, NADP nitrous oxide-forming nitric oxide reductase, NITRIC OXIDE, ... 著者 Tosha, T, Nomura, T, Nishida, T, Ueno, G, Murakami, H, Yamashita, K, Hirata, K, Yamamoto, M, Ago, H, Sugimoto, H, Shiro, Y, Kubo, M. 登録日 2017-08-09 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.36 Å) 主引用文献 Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate. Nat Commun, 8, 2017
5Y5K	Time-resolved SFX structure of cytochrome P450nor : 20 ms after photo-irradiation of caged NO in the absence of NADH (NO-bound state), light data 分子名称: NADP nitrous oxide-forming nitric oxide reductase, NITRIC OXIDE, PROTOPORPHYRIN IX CONTAINING FE 著者 Tosha, T, Nomura, T, Nishida, T, Saeki, N, Okubayashi, K, Yamagiwa, R, Sugahara, M, Nakane, T, Yamashita, K, Hirata, K, Ueno, G, Kimura, T, Hisano, T, Muramoto, K, Sawai, H, Takeda, H, Mizohata, E, Yamashita, A, Kanematsu, Y, Takano, Y, Nango, E, Tanaka, R, Nureki, O, Ikemoto, Y, Murakami, H, Owada, S, Tono, K, Yabashi, M, Yamamoto, M, Ago, H, Iwata, S, Sugimoto, H, Shiro, Y, Kubo, M. 登録日 2017-08-09 公開日 2017-12-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate. Nat Commun, 8, 2017
5YSM	Crystal Structure Analysis of Rif16 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Li, F.W, Qi, F.F, Xiao, Y.L, Zhao, G.P, Li, S.Y. 登録日 2017-11-14 公開日 2018-07-04 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Deciphering the late steps of rifamycin biosynthesis. Nat Commun, 9, 2018
5YLW	CYP76AH1 from Salvia miltiorrhiza 分子名称: Ferruginol synthase, MANGANESE (II) ION, PROTOPORPHYRIN IX CONTAINING FE 著者 Chang, Z. 登録日 2017-10-20 公開日 2018-10-24 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 CYP76AH1 from Salvia miltiorrhiza To Be Published
5YQH	The crystal structure of CYP199A4 binding with 4-n-Propyl benzoic acid 分子名称: 4-methoxybenzamide, CHLORIDE ION, Cytochrome P450, ... 著者 Zhou, W, Zhang, T, Qiao, R, Bell, S, Coleman, T. 登録日 2017-11-06 公開日 2019-02-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The crystal structure of CYP199A4 binding with 4-n-Propyl benzoic acid To Be Published
5Z9J	Identification of the functions of unusual cytochrome p450-like monooxygenases involved in microbial secondary metablism 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Putative P450-like enzyme, TRIS(HYDROXYETHYL)AMINOMETHANE 著者 Lu, M, Lin, L, Zhang, C, Chen, Y. 登録日 2018-02-03 公開日 2019-02-06 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Riboflavin Is Directly Involved in the N-Dealkylation Catalyzed by Bacterial Cytochrome P450 Monooxygenases. Chembiochem, 2020
5ZLH	Crystal structure of Mn-ProtoporphyrinIX-reconstituted P450BM3 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, MANGANESE PROTOPORPHYRIN IX 著者 Omura, K, Aiba, Y, Onoda, H, Sugimoto, H, Shoji, O, Watanabe, Y. 登録日 2018-03-28 公開日 2018-08-15 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Reconstitution of full-length P450BM3 with an artificial metal complex by utilising the transpeptidase Sortase A. Chem. Commun. (Camb.), 54, 2018
5Z9I	Identification of the functions of unusual cytochrome p450-like monooxygenases involved in microbial secondary metablism 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Putative P450-like enzyme 著者 Lu, M, Lin, L, Zhang, C, Chen, Y. 登録日 2018-02-03 公開日 2019-02-06 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 Riboflavin Is Directly Involved in the N-Dealkylation Catalyzed by Bacterial Cytochrome P450 Monooxygenases. Chembiochem, 2020
5ZIS	Crystal structure of Mn-ProtoporphyrinIX-reconstituted P450BM3 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, MANGANESE PROTOPORPHYRIN IX 著者 Omura, K, Aiba, Y, Onoda, H, Sugimoto, H, Shoji, O, Watanabe, Y. 登録日 2018-03-17 公開日 2018-08-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Reconstitution of full-length P450BM3 with an artificial metal complex by utilising the transpeptidase Sortase A. Chem. Commun. (Camb.), 54, 2018
6A17	Crystal structure of CYP90B1 in complex with brassinazole 分子名称: (2R,3S)-4-(4-chlorophenyl)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)butan-2-ol, CHLORIDE ION, Cytochrome P450 90B1, ... 著者 Fujiyama, K, Hino, T, Kanadani, M, Mizutani, M, Nagano, S. 登録日 2018-06-06 公開日 2019-06-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.301 Å) 主引用文献 Structural insights into a key step of brassinosteroid biosynthesis and its inhibition. Nat.Plants, 5, 2019
6A15	Structure of CYP90B1 in complex with cholesterol 分子名称: CHLORIDE ION, CHOLESTEROL, Cytochrome P450 90B1, ... 著者 Fujiyama, K, Hino, T, Kanadani, M, Mizutani, M, Nagano, S. 登録日 2018-06-06 公開日 2019-06-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Structural insights into a key step of brassinosteroid biosynthesis and its inhibition. Nat.Plants, 5, 2019
6A7J	Testerone bound CYP154C4 from Streptomyces sp. ATCC 11861 分子名称: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE 著者 Lee, C.W, Lee, J.H. 登録日 2018-07-03 公開日 2019-01-16 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Characterization of two steroid hydroxylases from different Streptomyces spp. and their ligand-bound and -unbound crystal structures. Febs J., 286, 2019
3SWZ	Human Cytochrome P450 17A1 in complex with TOK-001 分子名称: (3alpha,8alpha)-17-(1H-benzimidazol-1-yl)androsta-5,16-dien-3-ol, PROTOPORPHYRIN IX CONTAINING FE, Steroid 17-alpha-hydroxylase/17,20 lyase 著者 DeVore, N.M, Scott, E.E. 登録日 2011-07-14 公開日 2012-01-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of cytochrome P450 17A1 with prostate cancer drugs abiraterone and TOK-001. Nature, 482, 2012
3T3Z	Human Cytochrome P450 2E1 in complex with pilocarpine 分子名称: (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one, Cytochrome P450 2E1, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Meneely, K.M, DeVore, N.M, Scott, E.E. 登録日 2011-07-25 公開日 2011-12-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine. Febs J., 279, 2012
3T3R	Human Cytochrome P450 2A6 in complex with Pilocarpine 分子名称: (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one, Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE 著者 DeVore, N.M, Scott, E.E. 登録日 2011-07-25 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine. Febs J., 279, 2012
3TDA	Competitive replacement of thioridazine by prinomastat in crystals of cytochrome P450 2D6 分子名称: Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, Prinomastat, ... 著者 Wang, A, Stout, C.D, Johnson, E.F. 登録日 2011-08-10 公開日 2012-08-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding. J.Biol.Chem., 290, 2015
3T3Q	Human Cytochrome P450 2A6 I208S/I300F/G301A/S369G in complex with Pilocarpine 分子名称: (3S,4R)-3-ethyl-4-[(1-methyl-1H-imidazol-5-yl)methyl]dihydrofuran-2(3H)-one, Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE 著者 DeVore, N.M, Scott, E.E. 登録日 2011-07-25 公開日 2011-12-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural comparison of cytochromes P450 2A6, 2A13, and 2E1 with pilocarpine. Febs J., 279, 2012
1ODO	1.85 A structure of CYP154A1 from Streptomyces coelicolor A3(2) 分子名称: 4-PHENYL-1H-IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE, PUTATIVE CYTOCHROME P450 154A1 著者 Podust, L.M, Kim, Y, Arase, M, Bach, H, Sherman, D.H, Lamb, D.C, Kelly, S.L, Waterman, M.R. 登録日 2003-02-19 公開日 2004-01-02 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Comparison of the 1.85 A Structure of Cyp154A1 from Streptomyces Coelicolor A3(2) with the Closely Related Cyp154C1 and Cyps from Antibiotic Biosynthetic Pathways. Protein Sci., 13, 2004
1NOO	CYTOCHROME P450-CAM COMPLEXED WITH 5-EXO-HYDROXYCAMPHOR 分子名称: 5-EXO-HYDROXYCAMPHOR, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE 著者 Li, H.Y, Poulos, T.L. 登録日 1995-12-02 公開日 1996-03-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal Structure of Cytochrome P450-Cam Complexed with its Catalytic Product, 5-Exo-Hydroxycamphor J.Am.Chem.Soc., 117, 1995
1O76	CYANIDE COMPLEX OF P450CAM FROM PSEUDOMONAS PUTIDA 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CAMPHOR, CYANIDE ION, ... 著者 Fedorov, R, Ghosh, D, Schlichting, I. 登録日 2002-10-23 公開日 2002-12-19 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structures of Cyanide Complexes of P450Cam and the Oxygenase Domain of Inducible Nitric Oxide Synthase-Structural Models of the Short-Lived Oxygen Complexes Arch.Biochem.Biophys., 409, 2003
1OG2	Structure of human cytochrome P450 CYP2C9 分子名称: CYTOCHROME P450 2C9, HEME C 著者 Williams, P.A, Cosme, J, Ward, A, Angove, H.C, Matak Vinkovic, D, Jhoti, H. 登録日 2003-04-23 公開日 2003-07-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of Human Cytochrome P450 2C9 with Bound Warfarin Nature, 424, 2003
1OG5	Structure of human cytochrome P450 CYP2C9 分子名称: CYTOCHROME P450 2C9, HEME C, S-WARFARIN 著者 Williams, P.A, Cosme, J, Ward, A, Angove, H.C, Matak Vinkovic, D, Jhoti, H. 登録日 2003-04-24 公開日 2003-07-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal Structure of Human Cytochrome P450 2C9 with Bound Warfarin Nature, 424, 2003
3TBG	Human cytochrome P450 2D6 with two thioridazines bound in active site 分子名称: 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, Cytochrome P450 2D6, GLYCEROL, ... 著者 Wang, A, Stout, C.D, Johnson, E.F. 登録日 2011-08-05 公開日 2012-08-08 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Contributions of Ionic Interactions and Protein Dynamics to Cytochrome P450 2D6 (CYP2D6) Substrate and Inhibitor Binding. J.Biol.Chem., 290, 2015

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