PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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4LBV	Identifying ligand binding hot spots in proteins using brominated fragments 分子名称: AMMONIUM ION, CHLORIDE ION, Elongation factor Tu-A, ... 著者 Groftehauge, M.K, Therkelsen, M, Taaning, R, Skrydstrup, T, Morth, J.P, Nissen, P. 登録日 2013-06-21 公開日 2013-09-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Identifying ligand-binding hot spots in proteins using brominated fragments. Acta Crystallogr.,Sect.F, 69, 2013
4EAN	1.75A resolution structure of indole bound beta-glycosidase (W33G) from sulfolobus solfataricus 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-galactosidase, CHLORIDE ION, ... 著者 Lovell, S, Battaile, K.P, Deckert, K, Brunner, L.C, Budiardjo, S.J, Karanicolas, J. 登録日 2012-03-22 公開日 2012-06-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Designing allosteric control into enzymes by chemical rescue of structure. J.Am.Chem.Soc., 134, 2012
4L4R	Structural Characterisation of the Apo-form of Human Lactate Dehydrogenase M Isozyme 分子名称: L-lactate dehydrogenase A chain 著者 Dempster, S, Harper, S, Moses, J.E, Dreveny, I. 登録日 2013-06-09 公開日 2014-04-30 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural characterization of the apo form and NADH binary complex of human lactate dehydrogenase. Acta Crystallogr.,Sect.D, 70, 2014
4LCL	Simvastatin Synthase (LOVD), from Aspergillus Terreus, LovD6 mutant (simh6208) 分子名称: ISOPROPYL ALCOHOL, Transesterase 著者 Gao, X, Sawaya, M.R, Yeates, T.O, Tang, Y. 登録日 2013-06-21 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 The role of distant mutations and allosteric regulation on LovD active site dynamics. Nat.Chem.Biol., 10, 2014
4L5T	Crystal structure of the tetrameric p202 HIN2 分子名称: Interferon-activable protein 202 著者 Yin, Q, Tian, Y, Wu, H. 登録日 2013-06-11 公開日 2013-07-31 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.405 Å) 主引用文献 Molecular Mechanism for p202-Mediated Specific Inhibition of AIM2 Inflammasome Activation. Cell Rep, 4, 2013
4KV3	Ubiquitin-like domain of the Mycobacterium tuberculosis type VII secretion system protein EccD1 as maltose-binding protein fusion 分子名称: Chimera fusion protein of ESX-1 secretion system protein eccD1 and Maltose-binding periplasmic protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose 著者 Korotkov, K.V, Evans, T.J. 登録日 2013-05-22 公開日 2014-04-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structures of EccB1 and EccD1 from the core complex of the mycobacterial ESX-1 type VII secretion system. Bmc Struct.Biol., 16, 2016
4KAH	Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 4-bromo-1H-pyrazole 分子名称: 4-bromo-1H-pyrazole, ADENOSINE, BROMIDE ION, ... 著者 Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) 登録日 2013-04-22 公開日 2013-05-22 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with 4-bromo-1H-pyrazole To be Published
4EGG	Computationally Designed Self-assembling tetrahedron protein, T310 分子名称: GLYCEROL, Putative acetyltransferase SACOL2570 著者 Sawaya, M.R, King, N.P, Sheffler, W, Baker, D, Yeates, T.O. 登録日 2012-03-30 公開日 2012-05-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Computational design of self-assembling protein nanomaterials with atomic level accuracy. Science, 336, 2012
4K9E	Crystal structure of KIT D4D5 fragment in complex with anti-Kit antibodies Fab79D 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Mast/stem cell growth factor receptor Kit, heavy chain, ... 著者 Resheynyak, A.V, Boggon, T.J, Lax, I, Schlessinger, J. 登録日 2013-04-19 公開日 2013-10-16 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal region. Proc.Natl.Acad.Sci.USA, 110, 2013
4EH3	Human p38 MAP kinase in complex with NP-F2 and RL87 分子名称: Mitogen-activated protein kinase 14, NARINGENIN, N~4~-cyclopropyl-2-phenylquinazoline-4,7-diamine 著者 Over, B, Gruetter, C, Waldmann, H, Rauh, D. 登録日 2012-04-02 公開日 2012-12-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Natural-product-derived fragments for fragment-based ligand discovery. Nat Chem, 5, 2012
4KA8	Structure of Organellar OligoPeptidase 分子名称: CHLORIDE ION, GLYCEROL, Oligopeptidase A, ... 著者 Berntsson, R.P.-A, Kmiec, B, Teixeira, P.F, Svensson, L.M, Bakali, A, Glaser, E, Stenmark, P. 登録日 2013-04-22 公開日 2013-09-18 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts. Proc. Natl. Acad. Sci. U.S.A., 110, 2013
4EHY	Crystal structure of LpxK from Aquifex aeolicus in complex with ADP/Mg2+ at 2.2 angstrom resolution 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... 著者 Emptage, R.P, Daughtry, K.D, Pemble IV, C.W, Raetz, C.R.H. 登録日 2012-04-04 公開日 2012-08-29 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.199 Å) 主引用文献 Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface. Proc.Natl.Acad.Sci.USA, 109, 2012
4EY8	Crystal structure of recombinant human acetylcholinesterase in complex with fasciculin-2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Acetylcholinesterase, Fasciculin-2, ... 著者 Cheung, J, Rudolph, M, Burshteyn, F, Cassidy, M, Gary, E, Love, J, Height, J, Franklin, M. 登録日 2012-05-01 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.5958 Å) 主引用文献 Structures of human acetylcholinesterase in complex with pharmacologically important ligands. J.Med.Chem., 55, 2012
4KBR	Crystal structure of mouse Ceramide-1-phosphate transfer protein (apo-form) 分子名称: Glycolipid transfer protein domain-containing protein 1, PHOSPHATE ION 著者 Simanshu, D.K, Brown, R.E, Patel, D.J. 登録日 2013-04-23 公開日 2013-07-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.547 Å) 主引用文献 Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500, 2013
4E4J	Crystal structure of arginine deiminase from Mycoplasma penetrans 分子名称: Arginine deiminase, CHLORIDE ION 著者 Benach, J, Gallego, P, Planell, R, Querol, E, Perez Pons, J.A, Reverter, D. 登録日 2012-03-13 公開日 2012-10-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural Characterization of the Enzymes Composing the Arginine Deiminase Pathway in Mycoplasma penetrans. Plos One, 7, 2012
4KGN	Crystal structure of a tRNA (cytidine(34)-2'-O)-methyltransferase bound to S-adenosyl homocysteine 分子名称: CHLORIDE ION, S-ADENOSYL-L-HOMOCYSTEINE, tRNA (cytidine(34)-2'-O)-methyltransferase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-04-29 公開日 2013-05-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of a TrmH family tRNA methyltransferase bound to S-adenosyl homocysteine To be Published
4KNA	Crystal structure of an N-succinylglutamate 5-semialdehyde dehydrogenase from Burkholderia thailandensis 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2013-05-09 公開日 2013-06-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of an N-succinylglutamate 5-semialdehyde dehydrogenase from Burkholderia thailandensis TO BE PUBLISHED
4KS2	Influenza Neuraminidase in complex with antiviral compound (3S,4R,5R)-4-(acetylamino)-3-carbamimidamido-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid 分子名称: (3S,4R,5R)-4-(acetylamino)-3-carbamimidamido-5-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, CALCIUM ION, Neuraminidase 著者 Kerry, P.S, Russell, R.J.M. 登録日 2013-05-17 公開日 2013-10-30 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.595 Å) 主引用文献 Structural basis for a class of nanomolar influenza A neuraminidase inhibitors. Sci Rep, 3, 2013
4KRL	Nanobody/VHH domain 7D12 in complex with domain III of the extracellular region of EGFR, pH 6.0 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ferguson, K.M, Schmitz, K.R. 登録日 2013-05-16 公開日 2013-08-28 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.849 Å) 主引用文献 Structural Evaluation of EGFR Inhibition Mechanisms for Nanobodies/VHH Domains. Structure, 21, 2013
4K5C	From DARPins to LoopDARPins: Novel LoopDARPin Design Allows the Selection of Low Picomolar Binders in a Single Round of Ribosome Display 分子名称: Loop Designed Ankyrin Repeat Protein Nran1_G06_C 著者 Schilling, J, Schoeppe, J, Plueckthun, A. 登録日 2013-04-14 公開日 2013-11-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 From DARPins to LoopDARPins: novel LoopDARPin design allows the selection of low picomolar binders in a single round of ribosome display J.Mol.Biol., 426, 2014
4K84	Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 16:0 ceramide-1-phosphate (16:0-C1P) 分子名称: (2S,3R,4E)-2-(hexadecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1 著者 Simanshu, D.K, Brown, R.E, Patel, D.J. 登録日 2013-04-17 公開日 2013-07-17 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.897 Å) 主引用文献 Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids. Nature, 500, 2013
4K91	Crystal structure of Penicillin-Binding Protein 5 (PBP5) from Pseudomonas aeruginosa in apo state 分子名称: D-ala-D-ala-carboxypeptidase, SUCCINIC ACID 著者 Smith, J, Toth, M, Vakulenko, S, Mobashery, S, Chen, Y. 登録日 2013-04-19 公開日 2013-09-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural analysis of the role of Pseudomonas aeruginosa penicillin-binding protein 5 in beta-lactam resistance. Antimicrob.Agents Chemother., 57, 2013
4KE5	HCV NS5B GT1B N316Y with GSK5852 分子名称: HCV Polymerase, [4-({[5-cyclopropyl-2-(4-fluorophenyl)-3-(methylcarbamoyl)-1-benzofuran-6-yl](methylsulfonyl)amino}methyl)-2-fluorophenyl]boronic acid 著者 Williams, S.P, Kahler, K.M, Shotwell, J.B. 登録日 2013-04-25 公開日 2013-05-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase. J.Med.Chem., 57, 2014
4KGO	Crystal Structure of double Leucine to Methionine mutant human splunc1 lacking the secretion signal sequence 分子名称: BPI fold-containing family A member 1 著者 Betts, L, Walton, W.G. 登録日 2013-04-29 公開日 2013-09-25 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (3.194 Å) 主引用文献 Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways. Proc.Natl.Acad.Sci.USA, 110, 2013
4N45	Crystal structure of reduced form of thiolase from Clostridium acetobutylicum 分子名称: Acetyl-CoA acetyltransferase 著者 Kim, S, Ha, S.C, Ahn, J.W, Kim, E.J, Lim, J.H, Kim, K.J. 登録日 2013-10-08 公開日 2014-10-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structural insight into redox-switch regulatory mechanism of thiolase from the n-butanol synthesizing bacterium, Clostridium acetobutylicum to be published

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