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6ZLE
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BU of 6zle by Molmil
Solution structure of unliganded MLKL executioner domain
分子名称: Mixed lineage kinase domain-like protein
著者Ruebbelke, M, Bauer, M, Nar, H, Zeeb, M.
登録日2020-06-30
公開日2020-12-16
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis.
Proc.Natl.Acad.Sci.USA, 117, 2020
6ZPR
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BU of 6zpr by Molmil
Solution structure of MLKL executioner domain in complex with a covalent inhibitor
分子名称: 7-(2-methoxyethoxymethyl)-1,3-dimethyl-purine-2,6-dione, Mixed lineage kinase domain-like protein,Mixed lineage kinase domain-like protein
著者Ruebbelke, M, Bauer, M, Hamilton, J, Binder, F, Nar, H, Zeeb, M.
登録日2020-07-09
公開日2020-12-16
最終更新日2021-01-06
実験手法SOLUTION NMR
主引用文献Locking mixed-lineage kinase domain-like protein in its auto-inhibited state prevents necroptosis.
Proc.Natl.Acad.Sci.USA, 117, 2020
8QAQ
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BU of 8qaq by Molmil
Conformations of macrocyclic peptides sampled by exact NOEs: models for cell-permeability. Conformation 1 of omphalotin A in apolar solvents.
分子名称: TRP-MVA-ILE-MVA-MVA-SAR-MVA-IML-SAR-VAL-IML-SAR
著者Ruedisser, S.H, Matabaro, E, Sonderegger, L, Guentert, P, Kuenzler, M, Gossert, A.D.
登録日2023-08-23
公開日2023-12-06
最終更新日2024-01-03
実験手法SOLUTION NMR
主引用文献Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability.
J.Am.Chem.Soc., 145, 2023
7BPP
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BU of 7bpp by Molmil
Solution NMR structure of NF5; de novo designed protein with a novel fold
分子名称: NF5
著者Kobayashi, N, Sugiki, T, Fujiwara, T, Minami, S, Koga, R, Chikenji, G, Koga, N.
登録日2020-03-23
公開日2021-03-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Exploration of novel alpha-beta-protein folds through de novo design
Nat.Struct.Mol.Biol., 2023
7BPN
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BU of 7bpn by Molmil
Solution NMR structure of NF7; de novo designed protein with a novel fold
分子名称: NF7
著者Kobayashi, N, Sugiki, T, Fujiwara, T, Minami, S, Koga, R, Chikenji, G, Koga, N.
登録日2020-03-23
公開日2021-03-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Exploration of novel alpha-beta-protein folds through de novo design
Nat.Struct.Mol.Biol., 2023
7BPL
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BU of 7bpl by Molmil
Solution NMR structure of NF1; de novo designed protein with a novel fold
分子名称: NF1
著者Kobayashi, N, Sugiki, T, Fujiwara, T, Minami, S, Koga, R, Chikenji, G, Koga, N.
登録日2020-03-23
公開日2021-03-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Exploration of novel alpha-beta-protein folds through de novo design
Nat.Struct.Mol.Biol., 2023
7BPM
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BU of 7bpm by Molmil
Solution NMR structure of NF2; de novo designed protein with a novel fold
分子名称: NF2
著者Kobayashi, N, Sugiki, T, Fujiwara, T, Minami, S, Koga, R, Chikenji, G, Koga, N.
登録日2020-03-23
公開日2021-03-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Exploration of novel alpha-beta-protein folds through de novo design
Nat.Struct.Mol.Biol., 2023
7BQD
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BU of 7bqd by Molmil
Solution NMR structure of NF8 (knot fold); de novo designed protein with a novel fold
分子名称: NF8
著者Kobayashi, N, Sugiki, T, Fujiwara, T, Minami, S, Koga, R, Chikenji, G, Koga, N.
登録日2020-03-24
公開日2021-03-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Exploration of novel alpha-beta-protein folds through de novo design
Nat.Struct.Mol.Biol., 2023
5NPN
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BU of 5npn by Molmil
Refined structure of cytotoxin I
分子名称: Cytotoxin 1
著者Dubinnyi, M.A, Dubovskii, P.V, Arseniev, A.S.
登録日2017-04-17
公開日2018-04-04
最終更新日2019-05-08
実験手法SOLUTION NMR
主引用文献Structural and Dynamic "Portraits" of Recombinant and Native Cytotoxin I from Naja oxiana: How Close Are They?
Biochemistry, 56, 2017
8P25
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BU of 8p25 by Molmil
Solution structure of a chimeric U2AF2 RRM2 / FUBP1 N-Box
分子名称: Splicing factor U2AF 65 kDa subunit,Far upstream element-binding protein 1
著者Hipp, C, Sattler, M.
登録日2023-05-14
公開日2023-07-26
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献FUBP1 is a general splicing factor facilitating 3' splice site recognition and splicing of long introns.
Mol.Cell, 83, 2023
6LLQ
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BU of 6llq by Molmil
Solution NMR structure of de novo Rossmann2x2 fold with most of the core mutated to valine, R2x2_VAL88
分子名称: VAL88
著者Kobayashi, N, Sugiki, T, Fujiwara, T, Koga, R, Yamamoto, M, Kosugi, T, Koga, N.
登録日2019-12-23
公開日2020-12-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Robust folding of a de novo designed ideal protein even with most of the core mutated to valine.
Proc.Natl.Acad.Sci.USA, 117, 2020
6LXF
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BU of 6lxf by Molmil
Aromatic interactions drive the coupled folding and binding of the intrinsically disordered Sesbania mosaic virus VPg protein.
分子名称: Polyprotein
著者Dixit, K, Karanth, N.M, Nair, S, Kumari, K, Chakrabarti, K.S, Savithri, H.S, Sarma, S.P.
登録日2020-02-11
公開日2021-01-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Aromatic Interactions Drive the Coupled Folding and Binding of the Intrinsically Disordered Sesbania mosaic Virus VPg Protein.
Biochemistry, 59, 2020
6MIE
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BU of 6mie by Molmil
Solution NMR structure of the KCNQ1 voltage-sensing domain
分子名称: Potassium voltage-gated channel subfamily KQT member 1
著者Taylor, K.C, Kuenze, G, Smith, J.A, Meiler, J, McFeeters, R.L, Sanders, C.R.
登録日2018-09-19
公開日2020-03-04
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state.
Elife, 9, 2020
6MK7
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BU of 6mk7 by Molmil
Solution structure of the large extracellular loop of FtsX in Streptococcus pneumoniae
分子名称: Cell division protein FtsX
著者Edmonds, K.A, Fu, Y, Wu, H, Rued, B.E, Bruce, K.E, Winkler, M.E, Giedroc, D.P.
登録日2018-09-25
公開日2019-02-13
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae.
MBio, 10, 2019
8B8S
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BU of 8b8s by Molmil
Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3
分子名称: Serine/arginine (SR)-type shuttling mRNA binding protein NPL3
著者Kachariya, N, Sattler, M, Keil, P, Strasser, K.
登録日2022-10-04
公開日2022-11-09
最終更新日2024-06-19
実験手法SOLUTION NMR, SOLUTION SCATTERING
主引用文献Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic Acids Res., 51, 2023
8T3H
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BU of 8t3h by Molmil
Solution NMR structure alpha-helix 3 of Cry10Aa protein
分子名称: Pesticidal crystal protein Cry10Aa peptide
著者Barra, J.B, Freitas, C.D.P, Rios, T.B, Maximiano, M.R, Fernandes, F.C, Amorim, G.C, Porto, W.F, Grossi-de-Sa, M.F, Franco, O.F, Liao, L.M.
登録日2023-06-07
公開日2024-06-12
実験手法SOLUTION NMR
主引用文献Alpha-helix 3 of Cry10Aa protein
To Be Published
6S3W
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BU of 6s3w by Molmil
Solution NMR Structure of TolAIII Bound to a Peptide Derived from the N-terminus of TolB
分子名称: Cell envelope integrity/translocation protein TolA, TolBp
著者Kleanthous, C, Redfield, C, Rajasekar, K, Holmes, P.
登録日2019-06-26
公開日2020-03-25
最終更新日2024-07-03
実験手法SOLUTION NMR
主引用文献The lipoprotein Pal stabilises the bacterial outer membrane during constriction by a mobilisation-and-capture mechanism.
Nat Commun, 11, 2020
8URV
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BU of 8urv by Molmil
Solution NMR structure of pro-IL-18
分子名称: Interleukin-18
著者Bonin, J.P, Aramini, J.M, Kay, L.E.
登録日2023-10-26
公開日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural transitions enable interleukin-18 maturation and signaling.
Immunity, 2024
8UXR
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BU of 8uxr by Molmil
TxVIIB,U-superfamily conotoxin
分子名称: Conotoxin Tx6.5
著者Raffaelli, T, Daly, N.
登録日2023-11-09
公開日2024-03-27
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural analysis of a U-superfamily conotoxin containing a mini-granulin fold: Insights into key features that distinguish between the ICK and granulin folds.
J.Biol.Chem., 300, 2024
6O6W
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BU of 6o6w by Molmil
Solution structure of human myeloid-derived growth factor
分子名称: Myeloid-derived growth factor
著者Bortnov, V, Tonelli, M, Lee, W, Markley, J.L, Mosher, D.F.
登録日2019-03-07
公開日2019-11-13
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution structure of human myeloid-derived growth factor suggests a conserved function in the endoplasmic reticulum.
Nat Commun, 10, 2019
6OQP
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BU of 6oqp by Molmil
U-AITx-Ate1
分子名称: SER-LYS-TRP-ILE-CYS-ALA-ASN-ARG-SER-VAL-CYS-PRO-ILE
著者Elnahriry, K.A, Wai, D.C.C, Norton, R.S.
登録日2019-04-28
公開日2019-07-31
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural and functional characterisation of a novel peptide from the Australian sea anemone Actinia tenebrosa.
Toxicon, 168, 2019
5U6H
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BU of 5u6h by Molmil
Solution structure of the zinc fingers 1 and 2 of MBNL1
分子名称: Muscleblind-like protein 1, ZINC ION
著者Phukan, P.D, Park, S, Martinez-Yamout, M.M, Zeeb, M, Dyson, H.J, Wright, P.E.
登録日2016-12-08
公開日2017-08-02
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.
Biochemistry, 56, 2017
7N99
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BU of 7n99 by Molmil
SDE2 SAP domain apo structure
分子名称: Isoform 2 of Replication stress response regulator SDE2
著者Paung, Y, Weinheimer, A.S, Rageul, J, Khan, A, Ho, B, Tong, M, Alphonse, S, Seeliger, M.A, Kim, H.
登録日2021-06-17
公開日2022-10-12
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Extended DNA-binding interfaces beyond the canonical SAP domain contribute to the function of replication stress regulator SDE2 at DNA replication forks.
J.Biol.Chem., 298, 2022
7NWJ
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BU of 7nwj by Molmil
Solution NMR structure of the N-terminal domain of CEP164 (1-109)
分子名称: Centrosomal protein of 164 kDa
著者van Breugel, M, Rutherford, T.J.
登録日2021-03-16
公開日2021-09-15
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies.
Structure, 30, 2022
5GVO
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BU of 5gvo by Molmil
Solution NMR structure of a new lasso peptide sphaericin
分子名称: Uncharacterized protein
著者Hemmi, H, Kodani, S, Inoue, Y, Suzuki, M, Dohra, H, Suzuki, T, Ohnishi-Kameyama, M.
登録日2016-09-06
公開日2017-04-05
実験手法SOLUTION NMR
主引用文献Sphaericin, a Lasso Peptide from the Rare Actinomycete Planomonospora sphaerica
Eur.J.Org.Chem., 2017

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件を2024-07-10に公開中

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