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4O6I
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BU of 4o6i by Molmil
2.0A crystal structure of Lymphocytic Choriomeningitis Virus Nucleoprotein C-terminal Domain
分子名称: IMIDAZOLE, MAGNESIUM ION, Nucleoprotein, ...
著者West, B.R, Hastie, K.M, Saphire, E.O.
登録日2013-12-20
公開日2014-06-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the LCMV nucleoprotein provides a template for understanding arenavirus replication and immunosuppression.
Acta Crystallogr.,Sect.D, 70, 2014
4O72
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Crystal structure of the first bromodomain of human BRD4 in complex with NU7441
分子名称: 1,2-ETHANEDIOL, 8-(dibenzo[b,d]thiophen-4-yl)-2-(morpholin-4-yl)-4H-chromen-4-one, Bromodomain-containing protein 4, ...
著者Zhu, J.-Y, Ember, S.W, Watts, C, Schonbrunn, E.
登録日2013-12-24
公開日2014-03-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Acetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase Inhibitors.
Acs Chem.Biol., 9, 2014
3UGE
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BU of 3uge by Molmil
Silver Metallated Pseudomonas aeruginosa Azurin at 1.70 A
分子名称: Azurin, SILVER ION
著者Panzner, M.J, Billinovich, S.M, Parker, J.A, Bladholm, E, Berry, S.M, Ziegler, C.J, Leeper, T.C.
登録日2011-11-02
公開日2012-11-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Silver Metallation of Pseudomonas aeruginosa Azurin
To be Published
5DIG
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BU of 5dig by Molmil
Crystal Structure of the ER-alpha Ligand-binding Domain in complex with a trifluoromethyl-substituted A-CD ring estrogen derivative (1S,3aR,5S,7aS)-5-[4-hydroxy-2-(trifluoromethyl)phenyl]-7a-methyloctahydro-1H-inden-1-ol
分子名称: (1S,3aR,5S,7aS)-5-[4-hydroxy-2-(trifluoromethyl)phenyl]-7a-methyloctahydro-1H-inden-1-ol, Estrogen receptor, Nuclear receptor coactivator 2
著者Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W.
登録日2015-09-01
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Predictive features of ligand-specific signaling through the estrogen receptor.
Mol.Syst.Biol., 12, 2016
1MAA
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BU of 1maa by Molmil
MOUSE ACETYLCHOLINESTERASE CATALYTIC DOMAIN, GLYCOSYLATED PROTEIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ...
著者Bourne, Y, Taylor, P, Bougis, P.E, Marchot, P.
登録日1998-11-04
公開日1999-04-20
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of mouse acetylcholinesterase. A peripheral site-occluding loop in a tetrameric assembly.
J.Biol.Chem., 274, 1999
6D5F
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BU of 6d5f by Molmil
Cryo-EM reconstruction of membrane-enveloped filamentous virus SFV1 (Sulfolobus filamentous virus 1)
分子名称: DNA (336-MER), Fimbrial protein
著者Wang, F, Osinski, T, Liu, Y, Krupovic, M, Prangishvili, D, Egelman, E.H.
登録日2018-04-19
公開日2018-08-29
最終更新日2020-01-08
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural conservation in a membrane-enveloped filamentous virus infecting a hyperthermophilic acidophile.
Nat Commun, 9, 2018
5CZ8
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BU of 5cz8 by Molmil
Yeast 20S proteasome beta5-L(-49)S-K33A mutant in complex with Carfilzomib
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-07-31
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5D0Z
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BU of 5d0z by Molmil
Yeast 20S proteasome beta5-T1S mutant in complex with Carfilzomib
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
著者Huber, E.M, Groll, M.
登録日2015-08-03
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
3UKA
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BU of 3uka by Molmil
CRYSTAL STRUCTURE OF UDP-galactopyranose mutase from Aspergillus fumigatus
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, UDP-galactopyranose mutase
著者Van Straaten, K.E, Sanders, D.A.R.
登録日2011-11-09
公開日2012-02-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structural Insight into the Unique Substrate Binding Mechanism and Flavin Redox State of UDP-galactopyranose Mutase from Aspergillus fumigatus.
J.Biol.Chem., 287, 2012
6DAT
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BU of 6dat by Molmil
ETS1 in complex with synthetic SRR mimic
分子名称: Protein C-ets-1, SULFATE ION, serine-rich region (SRR) peptide
著者Perez-Borrajero, C, Okon, M, Lin, C.S, Scheu, K, Murphy, M.E.P, Graves, B.J, McIntosh, L.P.
登録日2018-05-02
公開日2019-01-16
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.35002637 Å)
主引用文献The Biophysical Basis for Phosphorylation-Enhanced DNA-Binding Autoinhibition of the ETS1 Transcription Factor.
J. Mol. Biol., 431, 2019
5D0T
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BU of 5d0t by Molmil
Yeast 20S proteasome beta5-D166N mutant in complex with MG132
分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(benzyloxy)carbonyl]-L-leucyl-N-[(2S)-1-hydroxy-4-methylpentan-2-yl]-L-leucinamide, ...
著者Huber, E.M, Groll, M.
登録日2015-08-03
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
3USQ
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BU of 3usq by Molmil
Structure of D159S/Y194F glycogenin mutant truncated at residue 270
分子名称: CHLORIDE ION, GLYCEROL, Glycogenin-1
著者Issoglio, F.M, Carrizo, M.E, Romero, J.M, Curtino, J.A.
登録日2011-11-23
公開日2011-12-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Mechanisms of monomeric and dimeric glycogenin autoglucosylation.
J.Biol.Chem., 287, 2012
4OOW
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BU of 4oow by Molmil
HCV NS5B polymerase with a fragment of quercetagetin
分子名称: CATECHOL, RNA-directed RNA polymerase
著者Guichou, J.F, Ahmed-Belkacem, A, Rozenn, B, Nazim, N, Hernandez, E, Pallier, C, Pawlotsky, J.M.
登録日2014-02-04
公開日2014-12-17
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Inhibition of RNA binding to hepatitis C virus RNA-dependent RNA polymerase: a new mechanism for antiviral intervention.
Nucleic Acids Res., 42, 2014
1M5Y
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BU of 1m5y by Molmil
Crystallographic Structure of SurA, a Molecular Chaperone that Facilitates Outer Membrane Porin Folding
分子名称: Survival protein surA
著者Bitto, E, McKay, D.B.
登録日2002-07-10
公開日2002-11-08
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystallographic Structure of SurA, a Molecular Chaperone that Facilitates Folding of Outer Membrane Porins
Structure, 10, 2002
5DBL
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BU of 5dbl by Molmil
Crystal structure of the Staphylococcus aureus SasG E1-G52 Y625W mutant
分子名称: Surface protein G
著者Whelan, F, Potts, J.R.
登録日2015-08-21
公開日2016-09-28
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Disorder drives cooperative folding in a multidomain protein.
Proc.Natl.Acad.Sci.USA, 113, 2016
5DCD
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BU of 5dcd by Molmil
Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase regulated (Tyrosine)
分子名称: MANGANESE (II) ION, Phospho-2-dehydro-3-deoxyheptonate aldolase, SULFATE ION, ...
著者Heyes, L.C, Parker, E.
登録日2015-08-24
公開日2016-08-24
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Structure of Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase regulated and complexed with PEP at 2.05 Angstroms
To Be Published
6Z7O
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BU of 6z7o by Molmil
Crystal structure of Thioredoxin T from Drosophila melanogaster
分子名称: Thioredoxin-T, ZINC ION
著者Freier, R, Aragon, E, Baginski, B, Pluta, R, Martin-Malpartida, P, Torner, C, Gonzaez, C, Macias, M.
登録日2020-05-31
公開日2020-10-21
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Structures of the germline-specific Deadhead and thioredoxin T proteins from Drosophila melanogaster reveal unique features among thioredoxins.
Iucrj, 8, 2021
4OVP
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BU of 4ovp by Molmil
CRYSTAL STRUCTURE OF A TRAP PERIPLASMIC SOLUTE BINDING PROTEIN FROM SULFITOBACTER sp. NAS-14.1, TARGET EFI-510292, WITH BOUND ALPHA-D-MANURONATE
分子名称: C4-dicarboxylate transport system substrate-binding protein, alpha-D-mannopyranuronic acid
著者Vetting, M.W, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Stead, M, Attonito, J.D, Scott Glenn, A, Chowdhury, S, Evans, B, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI)
登録日2013-12-11
公開日2014-01-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes.
Biochemistry, 54, 2015
3UGB
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BU of 3ugb by Molmil
UbcH5c~Ubiquitin Conjugate
分子名称: GLYCEROL, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D3
著者Page, R.C, Pruneda, J.N, Klevit, R.E, Misra, S.
登録日2011-11-02
公開日2012-05-16
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural insights into the conformation and oligomerization of E2~ubiquitin conjugates.
Biochemistry, 51, 2012
4OY9
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BU of 4oy9 by Molmil
Crystal structure of human P-Cadherin EC1-EC2 in closed conformation
分子名称: CALCIUM ION, Cadherin-3
著者Dalle Vedove, A, Lucarelli, A.P, Nardone, V, Matino, A, Parisini, E.
登録日2014-02-11
公開日2015-04-01
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献The X-ray structure of human P-cadherin EC1-EC2 in a closed conformation provides insight into the type I cadherin dimerization pathway.
Acta Crystallogr.,Sect.F, 71, 2015
3UJZ
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BU of 3ujz by Molmil
Crystal structure of enterohemorrhagic E. coli StcE
分子名称: Metalloprotease stcE, ZINC ION
著者Yu, A.C.Y, Strynadka, N.C.J.
登録日2011-11-08
公開日2012-05-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Insight into the Bacterial Mucinase StcE Essential to Adhesion and Immune Evasion during Enterohemorrhagic E. coli Infection.
Structure, 20, 2012
5DDK
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BU of 5ddk by Molmil
Succinyl-CoA:acetate CoA-transferase (AarCH6-N347A) in complex with CoA
分子名称: Acetyl-CoA hydrolase, CHLORIDE ION, COENZYME A, ...
著者Kappock, T.J, Mullins, E.A, Murphy, J.R.
登録日2015-08-25
公開日2016-05-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.127 Å)
主引用文献Functional Dissection of the Bipartite Active Site of the Class I Coenzyme A (CoA)-Transferase Succinyl-CoA:Acetate CoA-Transferase.
Front Chem, 4, 2016
4O7A
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BU of 4o7a by Molmil
Crystal structure of the first bromodomain of human BRD4 in complex with SB-409514
分子名称: 1,2-ETHANEDIOL, 3-[(3-chloro-4-hydroxyphenyl)amino]-4-(3-chlorophenyl)-1H-pyrrole-2,5-dione, Bromodomain-containing protein 4
著者Ember, S.W, Zhu, J.-Y, Watts, C, Schonbrunn, E.
登録日2013-12-24
公開日2014-03-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.34 Å)
主引用文献Acetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase Inhibitors.
Acs Chem.Biol., 9, 2014
5CZ7
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BU of 5cz7 by Molmil
Yeast 20S proteasome beta5-T1A beta5-K81R double mutant in complex with Bortezomib, propeptide expressed in cis
分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ...
著者Huber, E.M, Groll, M.
登録日2015-07-31
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5D0X
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BU of 5d0x by Molmil
Yeast 20S proteasome beta5-T1S mutant in complex with Bortezomib
分子名称: CHLORIDE ION, MAGNESIUM ION, N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE, ...
著者Huber, E.M, Groll, M.
登録日2015-08-03
公開日2016-03-23
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016

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