PDB: 14265 件ウェブページステータス検索Chemie searchBIRD

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6USR	Telomerase Reverse Transcriptase ternary complex, TERT:DNA:dGpCpp 分子名称: DNA (5'-D(*GP*GP*TP*CP*AP*GP*GP*TP*CP*AP*GP*GP*TP*CP*A)-3'), DNA/RNA (5'-R(*CP*UP*GP*AP*CP*CP*UP*GP*AP*C)-D(P*CP*T)-R(P*GP*AP*C)-D(P*C)-3'), MAGNESIUM ION, ... 著者 Schaich, M.A, Freudenthal, B.D. 登録日 2019-10-28 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.93 Å) 主引用文献 Mechanisms of nucleotide selection by telomerase. Elife, 9, 2020
6PFV	Structure of S. venezuelae RisG-WhiG-c-di-GMP complex: orthorhombic crystal form 分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), AmfC protein, RNA polymerase sigma factor 著者 Schumacher, M.A. 登録日 2019-06-22 公開日 2019-11-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 c-di-GMP Arms an Anti-sigma to Control Progression of Multicellular Differentiation in Streptomyces. Mol.Cell, 77, 2020
5L9X	Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 60s 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ... 著者 Gao, Y, Yang, W. 登録日 2016-06-12 公開日 2016-06-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
6W7A	The crystal structure of the 2009/H1N1/California PA endonuclease mutant E119D bound to DNA oligomer TAGCAT (uncleaved, 5mM overnight DNA soak) 分子名称: DNA (5'-D(P*TP*AP*GP*CP*AP*T)-3'), GLYCEROL, MANGANESE (II) ION, ... 著者 Cuypers, M.G, Kumar, G, Webb, T, White, S.W. 登録日 2020-03-18 公開日 2021-02-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structural insights into the substrate specificity of the endonuclease activity of the influenza virus cap-snatching mechanism. Nucleic Acids Res., 49, 2021
1EAH	PV2L COMPLEXED WITH ANTIVIRAL AGENT SCH48973 分子名称: 1[2-CHLORO-4-METHOXY-PHENYL-OXYMETHYL]-4-[2,6-DICHLORO-PHENYL-OXYMETHYL]-BENZENE, MYRISTIC ACID, POLIOVIRUS TYPE 2 COAT PROTEINS VP1 TO VP4 著者 Lentz, K, Arnold, E. 登録日 1997-07-22 公開日 1998-09-16 最終更新日 2023-04-19 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structure of poliovirus type 2 Lansing complexed with antiviral agent SCH48973: comparison of the structural and biological properties of three poliovirus serotypes. Structure, 5, 1997
6ONO	Complex structure of WhiB1 and region 4 of SigA in C2221 space group 分子名称: DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, RNA polymerase sigma factor SigA, ... 著者 Wan, T, Li, S.R, Beltran, D.G, Schacht, A, Becker, D.C, Zhang, L.M. 登録日 2019-04-22 公開日 2019-11-27 最終更新日 2020-01-22 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structural basis of non-canonical transcriptional regulation by the sigma A-bound iron-sulfur protein WhiB1 in M. tuberculosis. Nucleic Acids Res., 48, 2020
8T7T	CryoEM structure of the HisRS-like domain of human GCN2 分子名称: eIF-2-alpha kinase GCN2 著者 Yin, J.Z, Keszei, A.F.A, Mazhab-Jafari, M.T, Sicheri, F. 登録日 2023-06-21 公開日 2024-03-13 最終更新日 2024-09-25 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 The HisRS-like domain of GCN2 is a pseudoenzyme that can bind uncharged tRNA. Structure, 32, 2024
5KFY	Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 4 degree 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... 著者 Gao, Y, Yang, W. 登録日 2016-06-12 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Capture of a third Mg2+ is essential for catalyzing DNA synthesis. Science, 352, 2016
6NE8	Solution Structure of the Thioredoxin-like Domain of Arabidopsis NCP (NUCLEAR CONTROL OF PEP ACTIVITY) 分子名称: Thioredoxin-like fold domain-containing protein MRL7L, chloroplastic 著者 Liu, J, Chen, M, Zhou, P. 登録日 2018-12-17 公開日 2019-12-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 NCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches. Nat Commun, 10, 2019
3PHU	OTU Domain of Crimean Congo Hemorrhagic Fever Virus 分子名称: GLYCEROL, RNA-directed RNA polymerase L 著者 Akutsu, M, Ye, Y, Virdee, S, Komander, D. 登録日 2010-11-04 公開日 2011-02-02 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains. Proc.Natl.Acad.Sci.USA, 108, 2011
4DTU	RB69 DNA Polymerase Ternary Complex with dGTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTM	RB69 DNA Polymerase Ternary Complex with dCTP Opposite an Abasic Site and ddG/dC as the Penultimate Base-pair 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTP	RB69 DNA Polymerase Ternary Complex with dGTP Opposite an Abasic Site and ddA/dT as the Penultimate Base-pair 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
8IBX	Structure of R2 with 3'UTR and DNA in unwinding state 分子名称: 3'UTR, DNA (60-MER), Reverse transcriptase-like protein, ... 著者 Deng, P, Tan, S, Wang, J, Liu, J.J. 登録日 2023-02-10 公開日 2023-09-20 実験手法 ELECTRON MICROSCOPY (3.74 Å) 主引用文献 Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon. Cell, 186, 2023
8IBW	Structure of R2 with 3'UTR and DNA in binding state 分子名称: 3'UTR, DNA (60-MER), Reverse transcriptase-like protein, ... 著者 Deng, P, Tan, S, Wang, J, Liu, J.J. 登録日 2023-02-10 公開日 2023-09-20 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon. Cell, 186, 2023
8IBZ	Structure of R2 with 5'ORF and 3'UTR 分子名称: 5ORF-linker-3UTR, Reverse transcriptase-like protein, ZINC ION 著者 Deng, P, Tan, S, Wang, J, Liu, J.J. 登録日 2023-02-10 公開日 2023-09-20 実験手法 ELECTRON MICROSCOPY (3.04 Å) 主引用文献 Structural RNA components supervise the sequential DNA cleavage in R2 retrotransposon. Cell, 186, 2023
4DTX	RB69 DNA Polymerase Ternary Complex with dTTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair 分子名称: CALCIUM ION, DNA polymerase, DNA primer, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTN	RB69 DNA Polymerase Ternary Complex with dATP Opposite an Abasic Site and ddA/dT as the Penultimate Base-pair 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
4DTS	RB69 DNA Polymerase Ternary Complex with dCTP Opposite an Abasic Site and ddC/dG as the Penultimate Base-pair 分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA polymerase, ... 著者 Xia, S, Wang, J, Konigsberg, W.H. 登録日 2012-02-21 公開日 2012-06-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Contribution of Partial Charge Interactions and Base Stacking to the Efficiency of Primer Extension at and beyond Abasic Sites in DNA. Biochemistry, 51, 2012
7ZY4	Crystal structure of human CstF77 in complex with hFip1 分子名称: Cleavage stimulation factor subunit 3, GLYCEROL, hFip1 著者 Muckenfuss, L.M, Jinek, M. 登録日 2022-05-23 公開日 2022-09-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3' end biogenesis. Elife, 11, 2022
5O1T	Solution structure of the RNA binding domain of Nrd1 分子名称: Protein NRD1 著者 Martinez-Lumbreras, S, Perez-Canadillas, J.M. 登録日 2017-05-19 公開日 2017-08-02 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 The structure of transcription termination factor Nrd1 reveals an original mode for GUAA recognition. Nucleic Acids Res., 45, 2017
4OR5	Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4 分子名称: AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ... 著者 Gu, J, Babayeva, N.D, Suwa, Y, Baranovskiy, A.G, Price, D.H, Tahirov, T.H. 登録日 2014-02-10 公開日 2014-04-16 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4. Cell Cycle, 13, 2014
8J9A	Solution structure of ABD3 (residues 453-561) of human MED15 isoform 2 分子名称: Mediator of RNA polymerase II transcription subunit 15 著者 Zhang, H, Li, Y. 登録日 2023-05-03 公開日 2024-05-08 実験手法 SOLUTION NMR 主引用文献 Solution structure of ABD3 (residues 453-561) of human MED15 isoform 2 To Be Published
5MG2	Crystal structure of the second bromodomain of human TAF1 in complex with BAY-299 chemical probe 分子名称: 1,2-ETHANEDIOL, 6-(3-oxidanylpropyl)-2-(1,3,6-trimethyl-2-oxidanylidene-benzimidazol-5-yl)benzo[de]isoquinoline-1,3-dione, Transcription initiation factor TFIID subunit 1 著者 Tallant, C, Bouche, L, Holton, S.J, Fedorov, O, Siejka, P, Picaud, S, Krojer, T, Srikannathasan, V, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hartung, I.V, Haendler, B, Muller, S, Huber, K.V.M, Structural Genomics Consortium (SGC) 登録日 2016-11-20 公開日 2017-05-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains. J. Med. Chem., 60, 2017
6XU2	Human karyopherin RanBP5 (isoform-3) 分子名称: Antipain, Importin-5, NICKEL (II) ION 著者 Swale, C, McCarthy, A.A, Berger, I, Bieniossek, C, Delmas, B, Ruigrok, R.W.H, Crepin, T. 登録日 2020-01-17 公開日 2020-04-22 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.834 Å) 主引用文献 X-ray Structure of the Human Karyopherin RanBP5, an Essential Factor for Influenza Polymerase Nuclear Trafficking. J.Mol.Biol., 432, 2020

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