PDB: 2906 件ウェブページステータス検索Chemie searchBIRD

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6FE7	Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-356 分子名称: (4aS,8aR)-2-(1-{2-aminothieno[2,3-d]pyrimidin-4-yl}piperidin-4-yl)-4-(3,4- dimethoxyphenyl)-1,2,4a,5,8,8a-hexahydrophthalazin-1-one, 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Singh, A.K, Brown, D.G. 登録日 2017-12-29 公開日 2019-04-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 hPDE4D2 structure with inhibitor NPD-356 To be published
6FET	Crystal structure of human phosphodiesterase 4D2 catalytic domain with inhibitor NPD-1439 分子名称: 1,2-ETHANEDIOL, 1-(2-{4-[(4aS,8aR)-4-[3,4-bis(difluoromethoxy)phenyl]-1-oxo-1,2,4a,5,8,8a-hexahydrophthalazin-2-yl]piperidin-1-yl}-2-oxoethyl)-4,4-dimethylpiperidine-2,6-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Singh, A.K, Brown, D.G. 登録日 2018-01-03 公開日 2019-04-24 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 hPDE4D2 structure with inhibitor NPD-1439 To be published
6FTI	Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Programmed 80S Ribosome 分子名称: 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Braunger, K, Becker, T, Beckmann, R. 登録日 2018-02-22 公開日 2018-03-21 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum. Science, 360, 2018
1K73	Co-crystal Structure of Anisomycin Bound to the 50S Ribosomal Subunit 分子名称: 23S RRNA, 5S RRNA, ANISOMYCIN, ... 著者 Hansen, J, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A. 登録日 2001-10-18 公開日 2003-07-22 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit J.Mol.Biol., 330, 2003
1K8A	Co-crystal structure of Carbomycin A bound to the 50S ribosomal subunit of Haloarcula marismortui 分子名称: 23S RRNA, 5S RRNA, CADMIUM ION, ... 著者 Hansen, J.L, Ippolito, J.A, Ban, N, Nissen, P, Moore, P.B, Steitz, T. 登録日 2001-10-23 公開日 2002-07-19 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structures of four macrolide antibiotics bound to the large ribosomal subunit. Mol.Cell, 10, 2002
4BGU	1.50 A resolution structure of the malate dehydrogenase from Haloferax volcanii 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, CHLORIDE ION, ... 著者 Talon, R, Madern, D, Girard, E. 登録日 2013-03-28 公開日 2014-04-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.487 Å) 主引用文献 Insight Into Structural Evolution of Extremophilic Proteins To be Published
3OAA	Structure of the E.coli F1-ATP synthase inhibited by subunit Epsilon 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP synthase epsilon chain, ATP synthase gamma chain, ... 著者 Cingolani, G, Duncan, T.M. 登録日 2010-08-05 公開日 2011-05-25 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.26 Å) 主引用文献 Structural basis for inhibition of bacterial ATP synthase by subunit epsilon of the rotor stalk To be Published
4APZ	Structure of B. subtilis genomic dUTPase YncF in complex with dU, PPi and Mg in P1 分子名称: 2'-DEOXYURIDINE, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Garcia-Nafria, J, Timm, J, Harrison, C, Turkenburg, J.P, Wilson, K.S. 登録日 2012-04-11 公開日 2013-04-24 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Tying Down the Arm in Bacillus Dutpase: Structure and Mechanism Acta Crystallogr.,Sect.D, 69, 2013
1Q7Y	Crystal Structure of CCdAP-Puromycin bound at the Peptidyl transferase center of the 50S ribosomal subunit 分子名称: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ... 著者 Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A. 登録日 2003-08-20 公開日 2003-10-07 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural Insights Into Peptide Bond Formation Proc.Natl.Acad.Sci.USA, 99, 2002
1QVG	Structure of CCA oligonucleotide bound to the tRNA binding sites of the large ribosomal subunit of Haloarcula marismortui 分子名称: 23S ribosomal rna, 50S RIBOSOMAL PROTEIN L10E, 50S ribosomal protein L13P, ... 著者 Schmeing, T.M, Moore, P.B, Steitz, T.A. 登録日 2003-08-27 公開日 2003-11-11 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit RNA, 9, 2003
1Q86	Crystal structure of CCA-Phe-cap-biotin bound simultaneously at half occupancy to both the A-site and P-site of the the 50S ribosomal Subunit. 分子名称: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ... 著者 Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A. 登録日 2003-08-20 公開日 2003-10-07 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural insights into peptide bond formation. Proc.Natl.Acad.Sci.USA, 99, 2002
4AQY	Structure of ribosome-apramycin complexes 分子名称: 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... 著者 Matt, T, Ng, C.L, Lang, K, Sha, S.H, Akbergenov, R, Shcherbakov, D, Meyer, M, Duscha, S, Xie, J, Dubbaka, S.R, Perez-Fernandez, D, Vasella, A, Ramakrishnan, V, Schacht, J, Bottger, E.C. 登録日 2012-04-20 公開日 2012-07-18 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Dissociation of Antibacterial Activity and Aminoglycoside Ototoxicity in the 4-Monosubstituted 2-Deoxystreptamine Apramycin. Proc.Natl.Acad.Sci.USA, 109, 2012
4P6F	Crystal structure of the peptolide 12C bound to bacterial ribosome 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Fagan, C.E, Dunham, C.M. 登録日 2014-03-24 公開日 2014-10-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Macrolide-Peptide Conjugates as Probes of the Path of Travel of the Nascent Peptides through the Ribosome. Acs Chem.Biol., 9, 2014
4P70	Crystal Structure of Unmodified tRNA Proline (CGG) Bound to Codon CCG on the Ribosome 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Maehigashi, T, Dunkle, J.A, Dunham, C.M. 登録日 2014-03-25 公開日 2014-08-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.68 Å) 主引用文献 Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
4P99	Ca2+-stabilized adhesin helps an Antarctic bacterium reach out and bind ice 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... 著者 Guo, S, Vance, D.R.T, Campbell, R.L, Davies, P.L. 登録日 2014-04-02 公開日 2014-06-18 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Ca2+-stabilized adhesin helps an Antarctic bacterium reach out and bind ice. Biosci.Rep., 34, 2014
1Q81	Crystal Structure of minihelix with 3' puromycin bound to A-site of the 50S ribosomal subunit. 分子名称: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ... 著者 Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A. 登録日 2003-08-20 公開日 2003-10-07 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structural Insights into Peptide Bond Formation Proc.Natl.Acad.Sci.USA, 99, 2002
1QZV	Crystal structure of plant photosystem I 分子名称: CHLOROPHYLL A, IRON/SULFUR CLUSTER, PHYLLOQUINONE, ... 著者 Ben-Shem, A, Frolow, F, Nelson, N. 登録日 2003-09-18 公開日 2004-01-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (4.44 Å) 主引用文献 Crystal structure of plant photosystem I. Nature, 426, 2003
4AYG	Lactobacillus reuteri N-terminally truncated glucansucrase GTF180 in orthorhombic apo-form 分子名称: ACETIC ACID, CALCIUM ION, GLUCANSUCRASE, ... 著者 Pijning, T, Vujicic-Zagar, A, Kralj, S, Dijkhuizen, L, Dijkstra, B.W. 登録日 2012-06-21 公開日 2013-07-03 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Flexibility of Truncated and Full-Length Glucansucrase Gtf180 Enzymes from Lactobacillus Reuteri 180. FEBS J., 281, 2014
4B3S	Crystal structure of the 30S ribosome in complex with compound 37 分子名称: (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-4-O-benzyl-2-deoxy-alpha-D-glucopyranoside, 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Ng, C.L, Lang, K, Shcherbakov, D, Matt, T, Perez-Fernandez, D, Patak, R, Meyer, M, Duscha, S, Akbergenov, R, Boukari, H, Freihofer, P, Kudyba, I, Reddy, M.S.K, Nandurikar, R.S, Ramakrishnan, V, Vasella, A, Bottger, E.C. 登録日 2012-07-26 公開日 2013-08-07 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics Nat.Commun., 5, 2014
4NIA	Satellite Tobacco Mosaic Virus Refined at room temperature to 1.8 A Resolution using NCS Restraints 分子名称: Coat protein, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Larson, S.B, Day, J.S, McPherson, A. 登録日 2013-11-05 公開日 2014-09-10 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Satellite tobacco mosaic virus refined to 1.4 angstrom resolution. Acta Crystallogr.,Sect.D, 70, 2014
4BTS	THE CRYSTAL STRUCTURE OF THE EUKARYOTIC 40S RIBOSOMAL SUBUNIT IN COMPLEX WITH EIF1 AND EIF1A 分子名称: 18S ribosomal RNA, 40S RIBOSOMAL PROTEIN RACK1, 40S RIBOSOMAL PROTEIN RPS10E, ... 著者 Weisser, M, Voigts-Hoffmann, F, Rabl, J, Leibundgut, M, Ban, N. 登録日 2013-06-19 公開日 2013-07-17 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.703 Å) 主引用文献 The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A. Nat. Struct. Mol. Biol., 20, 2013
4B3R	Crystal structure of the 30S ribosome in complex with compound 30 分子名称: (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-4,6-O-[(1R)-3-phenylpropylidene]-alpha-D-glucopyranoside, 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Ng, C.L, Lang, K, Shcherbakov, D, Matt, T, Perez-Fernandez, D, Patak, R, Meyer, M, Duscha, S, Akbergenov, R, Boukari, H, Freihofer, P, Kudyba, I, Reddy, M.S.K, Nandurikar, R.S, Ramakrishnan, V, Vasella, A, Bottger, E.C. 登録日 2012-07-26 公開日 2013-08-07 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics Nat.Commun., 5, 2014
4B3T	Crystal structure of the 30S ribosome in complex with compound 39 分子名称: (2S,3S,4R,5R,6R)-2-(aminomethyl)-5-azanyl-6-[(2R,3S,4R,5S)-5-[(1R,2R,3S,5R,6S)-3,5-bis(azanyl)-2-[(2S,3R,4R,5S,6R)-3-azanyl-5-[(4-chlorophenyl)methoxy]-6-(hydroxymethyl)-4-oxidanyl-oxan-2-yl]oxy-6-oxidanyl-cyclohexyl]oxy-2-(hydroxymethyl)-4-oxidanyl-oxolan-3-yl]oxy-oxane-3,4-diol, 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Ng, C.L, Lang, K, Shcherbakov, D, Matt, T, Perez-Fernandez, D, Patak, R, Meyer, M, Duscha, S, Akbergenov, R, Boukari, H, Freihofer, P, Kudyba, I, Reddy, M.S.K, Nandurikar, R.S, Ramakrishnan, V, Vasella, A, Bottger, E.C. 登録日 2012-07-26 公開日 2013-08-07 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 4'-O-Substitutions Determine Selectivity of Aminoglycoside Antibiotics Nat.Commun., 5, 2014
4OA5	X-ray crystal structure of an O-methyltransferase from Anaplasma phagocytophilum bound to SAH solved by iodide SAD phasing 分子名称: 1,2-ETHANEDIOL, GLYCEROL, IODIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2014-01-03 公開日 2014-03-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 An O-Methyltransferase Is Required for Infection of Tick Cells by Anaplasma phagocytophilum. Plos Pathog., 11, 2015
3PIP	Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the large ribosomal subunit 分子名称: 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, ... 著者 Belousoff, M.J, Shapira, T, Bashan, A, Zimmerman, E, Kinashi, H, Rozenberg, H, Yonath, A. 登録日 2010-11-07 公開日 2011-02-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. Proc.Natl.Acad.Sci.USA, 108, 2011

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