8WAN
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![BU of 8wan by Molmil](/molmil-images/mine/8wan) | Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II positioned 4nt downstream of TSS. | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | 登録日 | 2023-09-07 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (6.07 Å) | 主引用文献 | Structural visualization of transcription initiation in action. Science, 382, 2023
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8WAL
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![BU of 8wal by Molmil](/molmil-images/mine/8wal) | Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II positioned 3nt downstream of TSS. | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | 登録日 | 2023-09-07 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (8.52 Å) | 主引用文献 | Structural visualization of transcription initiation in action. Science, 382, 2023
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8WAK
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![BU of 8wak by Molmil](/molmil-images/mine/8wak) | Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II positioned 2nt downstream of TSS. | 分子名称: | Alpha-amanitin, CDK-activating kinase assembly factor MAT1, DNA-directed RNA polymerase II subunit E, ... | 著者 | Chen, X, Liu, W, Wang, Q, Wang, X, Ren, Y, Qu, X, Li, W, Xu, Y. | 登録日 | 2023-09-07 | 公開日 | 2023-12-06 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (5.47 Å) | 主引用文献 | Structural visualization of transcription initiation in action. Science, 382, 2023
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8WAG
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![BU of 8wag by Molmil](/molmil-images/mine/8wag) | Crystal structure of the C-terminal fragment (residues 716-982) of Arabidopsis thaliana CHUP1 | 分子名称: | Protein CHUP1, chloroplastic | 著者 | Shimada, A, Nakamura, Y, Takano, A, Kohda, D. | 登録日 | 2023-09-07 | 公開日 | 2024-01-17 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (3.003 Å) | 主引用文献 | CHLOROPLAST UNUSUAL POSITIONING 1 is a plant-specific actin polymerization factor regulating chloroplast movement. Plant Cell, 36, 2024
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8WAF
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![BU of 8waf by Molmil](/molmil-images/mine/8waf) | Crystal structure of the C-terminal fragment (residues 756-982 with the C864S mutation) of Arabidopsis thaliana CHUP1 | 分子名称: | Protein CHUP1, chloroplastic | 著者 | Shimada, A, Takano, A, Nakamura, Y, Kohda, D. | 登録日 | 2023-09-07 | 公開日 | 2024-01-17 | 最終更新日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | CHLOROPLAST UNUSUAL POSITIONING 1 is a plant-specific actin polymerization factor regulating chloroplast movement. Plant Cell, 36, 2024
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8WAA
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![BU of 8waa by Molmil](/molmil-images/mine/8waa) | Human transketolase soaked with donor ketose D-xylulose | 分子名称: | 1,2-ETHANEDIOL, 2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, ... | 著者 | Liu, Z, Dai, S, Tittmann, K. | 登録日 | 2023-09-07 | 公開日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Multifaceted Role of the Substrate Phosphate Group in Transketolase Catalysis Acs Catalysis, 14, 2024
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8WA7
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![BU of 8wa7 by Molmil](/molmil-images/mine/8wa7) | E.coli transketolase soaked with donor ketose D-fructose | 分子名称: | 1,2-ETHANEDIOL, 2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, GLYCEROL, ... | 著者 | Liu, Z, Dai, S, Tittmann, K. | 登録日 | 2023-09-07 | 公開日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | 主引用文献 | Multifaceted Role of the Substrate Phosphate Group in Transketolase Catalysis Acs Catalysis, 14, 2024
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8WA5
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8WA3
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![BU of 8wa3 by Molmil](/molmil-images/mine/8wa3) | Cryo-EM structure of peptide free and Gs-coupled GIPR | 分子名称: | Gastric inhibitory polypeptide receptor,Fusion protein, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1,O-antigen polymerase, ... | 著者 | Cong, Z.T, Zhao, F.H, Li, Y, Luo, G, Zhou, Q.T, Yang, D.H, Wang, M.W. | 登録日 | 2023-09-06 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Molecular features of the ligand-free GLP-1R, GCGR and GIPR in complex with G s proteins. Cell Discov, 10, 2024
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8WA2
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![BU of 8wa2 by Molmil](/molmil-images/mine/8wa2) | cryo-EM structure of native mastigonemes isolated from Chlamydomonas reinhardtii at 3.0 angstrom resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Huang, J, Tao, H, Chen, J, Pan, J, Yan, C, Yan, N. | 登録日 | 2023-09-06 | 公開日 | 2024-04-10 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure-guided discovery of protein and glycan components in native mastigonemes. Cell, 187, 2024
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8W9Y
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![BU of 8w9y by Molmil](/molmil-images/mine/8w9y) | The cryo-EM structure of human sphingomyelin synthase-related protein | 分子名称: | Sphingomyelin synthase-related protein 1 | 著者 | Hu, K, Zhang, Q, Chen, Y, Yao, D, Zhou, L, Cao, Y. | 登録日 | 2023-09-06 | 公開日 | 2024-02-28 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis. Nat.Struct.Mol.Biol., 31, 2024
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8W9W
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![BU of 8w9w by Molmil](/molmil-images/mine/8w9w) | The cryo-EM structure of human sphingomyelin synthase-related protein in complex with ceramide/phosphoethanolamine | 分子名称: | PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, Sphingomyelin synthase-related protein 1, ~{N}-[(~{Z},2~{S},3~{R})-1,3-bis(oxidanyl)heptadec-4-en-2-yl]dodecanamide | 著者 | Hu, K, Zhang, Q, Chen, Y, Yao, D, Zhou, L, Cao, Y. | 登録日 | 2023-09-06 | 公開日 | 2024-02-28 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | 主引用文献 | Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis. Nat.Struct.Mol.Biol., 31, 2024
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8W9J
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8W9H
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![BU of 8w9h by Molmil](/molmil-images/mine/8w9h) | Crystal structure of anti-human CLEC12A antibody 50C1 | 分子名称: | 1,2-ETHANEDIOL, SULFATE ION, anti-human CLEC12A antibody 50C1 Fab Heavy chain, ... | 著者 | Mori, S, Nagae, M, Yamasaki, S. | 登録日 | 2023-09-05 | 公開日 | 2024-03-06 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands. Int.Immunol., 36, 2024
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8W8T
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![BU of 8w8t by Molmil](/molmil-images/mine/8w8t) | Crystal structure of human CLEC12A CRD | 分子名称: | C-type lectin domain family 12 member A, SULFATE ION | 著者 | Mori, S, Nagae, M, Yamasaki, S. | 登録日 | 2023-09-04 | 公開日 | 2024-03-06 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands. Int.Immunol., 36, 2024
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8W8K
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![BU of 8w8k by Molmil](/molmil-images/mine/8w8k) | Crystal structures of HSP90 and the compound Ganetespid in the "closed" conformation | 分子名称: | 5-[2,4-dihydroxy-5-(propan-2-yl)phenyl]-4-(1-methyl-1H-indol-5-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one, Heat shock protein HSP 90-alpha, MAGNESIUM ION | 著者 | Xu, C, Zhang, X.L, Bai, F. | 登録日 | 2023-09-03 | 公開日 | 2024-04-17 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Accurate Characterization of Binding Kinetics and Allosteric Mechanisms for the HSP90 Chaperone Inhibitors Using AI-Augmented Integrative Biophysical Studies. Jacs Au, 4, 2024
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8W87
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![BU of 8w87 by Molmil](/molmil-images/mine/8w87) | Cryo-EM structure of the METH-TAAR1 complex | 分子名称: | (2S)-N-methyl-1-phenylpropan-2-amine, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Liu, H, Zheng, Y, Wang, Y, Wang, Y, He, X, Xu, P, Huang, S, Yuan, Q, Zhang, X, Wang, S, Xu, H.E, Xu, F. | 登録日 | 2023-09-01 | 公開日 | 2023-11-22 | 最終更新日 | 2024-01-03 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Recognition of methamphetamine and other amines by trace amine receptor TAAR1. Nature, 624, 2023
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8W86
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![BU of 8w86 by Molmil](/molmil-images/mine/8w86) | HLA-DQ2.5-B/C hordein peptide in complex with DQN0385AE02 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DQN0385AE02 Fab heavy chain, DQN0385AE02 Fab light chain, ... | 著者 | Irie, M, Tsushima, T, Teranishi-Ikawa, Y, Takahashi, N, Ishii, S, Okura, Y, Fukami, T.A, Torizawa, T. | 登録日 | 2023-08-31 | 公開日 | 2023-11-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.236 Å) | 主引用文献 | Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease. Nat Commun, 14, 2023
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8W85
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![BU of 8w85 by Molmil](/molmil-images/mine/8w85) | HLA-DQ2.5-gamma2 gliadin peptide in complex with DQN0385AE01 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DQN0385AE01 Fab heavy chain, DQN0385AE01 Fab light chain, ... | 著者 | Irie, M, Tsushima, T, Teranishi-Ikawa, Y, Takahashi, N, Ishii, S, Okura, Y, Fukami, T.A, Torizawa, T. | 登録日 | 2023-08-31 | 公開日 | 2023-11-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.769 Å) | 主引用文献 | Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease. Nat Commun, 14, 2023
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8W84
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![BU of 8w84 by Molmil](/molmil-images/mine/8w84) | HLA-DQ2.5-alpha2 gliadin peptide in complex with DQN0344AE02 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DQN0344AE02 Fab heavy chain, DQN0344AE02 Fab light chain, ... | 著者 | Irie, M, Tsushima, T, Teranishi-Ikawa, Y, Takahashi, N, Ishii, S, Okura, Y, Fukami, T.A, Torizawa, T. | 登録日 | 2023-08-31 | 公開日 | 2023-11-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.105 Å) | 主引用文献 | Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease. Nat Commun, 14, 2023
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8W83
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![BU of 8w83 by Molmil](/molmil-images/mine/8w83) | HLA-DQ2.5-alpha1 gliadin peptide in complex with DQN0344AE02 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DQN0344AE02 Fab heavy chain, DQN0344AE02 Fab light chain, ... | 著者 | Irie, M, Tsushima, T, Teranishi-Ikawa, Y, Takahashi, N, Ishii, S, Okura, Y, Fukami, T.A, Torizawa, T. | 登録日 | 2023-08-31 | 公開日 | 2023-11-08 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.818 Å) | 主引用文献 | Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease. Nat Commun, 14, 2023
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8W7P
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![BU of 8w7p by Molmil](/molmil-images/mine/8w7p) | Extracellular domain of a sensor histidine kinase | 分子名称: | Extracellular domain of a sensor histidine kinase NagS, GLYCEROL | 著者 | Itoh, T, Ogawa, T, Hibi, T, Kimoto, H. | 登録日 | 2023-08-31 | 公開日 | 2024-01-10 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Characterization of the extracellular domain of sensor histidine kinase NagS from Paenibacillus sp. str. FPU-7: nagS interacts with oligosaccharide binding protein NagB1 in complexes with N, N'-diacetylchitobiose. Biosci.Biotechnol.Biochem., 88, 2024
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8W7N
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![BU of 8w7n by Molmil](/molmil-images/mine/8w7n) | Crystal structure of the in-cell Cry1Aa purified from Bacillus thuringiensis | 分子名称: | Pesticidal crystal protein Cry1Aa, UNKNOWN ATOM OR ION | 著者 | Tanaka, J, Abe, S, Hayakawa, T, Kojima, M, Yamashita, K, Hirata, K, Ueno, T. | 登録日 | 2023-08-31 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Crystal structure of the in-cell Cry1Aa purified from Bacillus thuringiensis. Biochem.Biophys.Res.Commun., 685, 2023
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8W7H
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![BU of 8w7h by Molmil](/molmil-images/mine/8w7h) | Purine Nucleoside Phosphorylase in complex with MMV000848 | 分子名称: | (2R)-1-(9H-carbazol-9-yl)-3-(cyclopentylamino)propan-2-ol, 1,2-ETHANEDIOL, PHOSPHATE ION, ... | 著者 | Chung, Z, Lin, J.Q, Lescar, J. | 登録日 | 2023-08-30 | 公開日 | 2024-01-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Identification and structural validation of purine nucleoside phosphorylase from Plasmodium falciparum as a target of MMV000848. J.Biol.Chem., 300, 2023
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8W7D
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![BU of 8w7d by Molmil](/molmil-images/mine/8w7d) | Crystal structure of EcPPAT-FR901483 complex | 分子名称: | Amidophosphoribosyltransferase, [(1S,3S,6S,7S,8R,9S)-6-[(4-methoxyphenyl)methyl]-3-(methylamino)-7-oxidanyl-5-azatricyclo[6.3.1.0^1,5]dodecan-9-yl] dihydrogen phosphate | 著者 | Hara, K, Hashimoto, H, Nakahara, M, Sato, M, Watanabe, K. | 登録日 | 2023-08-30 | 公開日 | 2023-12-13 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Uncommon Arrangement of Self-resistance Allows Biosynthesis of de novo Purine Biosynthesis Inhibitor that Acts as an Immunosuppressor. J.Am.Chem.Soc., 145, 2023
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