8W85
HLA-DQ2.5-gamma2 gliadin peptide in complex with DQN0385AE01
Summary for 8W85
Entry DOI | 10.2210/pdb8w85/pdb |
Descriptor | DQN0385AE01 Fab heavy chain, DQN0385AE01 Fab light chain, HLA class II histocompatibility antigen, DQ alpha 1 chain, ... (5 entities in total) |
Functional Keywords | celiac disease, antibody, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 188170.58 |
Authors | Irie, M.,Tsushima, T.,Teranishi-Ikawa, Y.,Takahashi, N.,Ishii, S.,Okura, Y.,Fukami, T.A.,Torizawa, T. (deposition date: 2023-08-31, release date: 2023-11-08, Last modification date: 2024-05-08) |
Primary citation | Okura, Y.,Ikawa-Teranishi, Y.,Mizoroki, A.,Takahashi, N.,Tsushima, T.,Irie, M.,Harfuddin, Z.,Miura-Okuda, M.,Ito, S.,Nakamura, G.,Takesue, H.,Ozono, Y.,Nishihara, M.,Yamada, K.,Gan, S.W.,Hayasaka, A.,Ishii, S.,Wakabayashi, T.,Muraoka, M.,Nagaya, N.,Hino, H.,Nemoto, T.,Kuramochi, T.,Torizawa, T.,Shimada, H.,Kitazawa, T.,Okazaki, M.,Nezu, J.,Sollid, L.M.,Igawa, T. Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease. Nat Commun, 14:8502-8502, 2023 Cited by PubMed: 38135691DOI: 10.1038/s41467-023-44083-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.769 Å) |
Structure validation
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