PDB: 31188 件ウェブページステータス検索Chemie searchBIRD

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9FB2	Gcase in complex with small molecule inhibitor 1 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Tisi, D, Cleasby, A. 登録日 2024-05-11 公開日 2024-07-03 最終更新日 2024-07-24 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of beta-Glucocerebrosidase. J.Med.Chem., 67, 2024
6X68	Cryo-EM structure of piggyBac transposase synaptic complex with hairpin DNA (SNHP) 分子名称: CALCIUM ION, Transposase, ZINC ION, ... 著者 Chen, Q, Hickman, A.B, Dyda, F. 登録日 2020-05-27 公開日 2020-07-22 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.66 Å) 主引用文献 Structural basis of seamless excision and specific targeting by piggyBac transposase Nat Commun, 11, 2020
6X67	Cryo-EM structure of piggyBac transposase strand transfer complex (STC) 分子名称: CALCIUM ION, DNA (37-MER), DNA (47-MER), ... 著者 Chen, Q, Hickman, A.B, Dyda, F. 登録日 2020-05-27 公開日 2020-07-22 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 Structural basis of seamless excision and specific targeting by piggyBac transposase Nat Commun, 11, 2020
4PI0	Crystal structure of particulate methane monooxygenase from Methylocystis sp. ATCC 49242 (Rockwell) soaked in copper 分子名称: COPPER (II) ION, Particulate methane monooxygenase subunit A, Particulate methane monooxygenase subunit B, ... 著者 Sirajuddin, S, Rosenzweig, A.C. 登録日 2014-05-07 公開日 2014-06-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.15 Å) 主引用文献 Effects of zinc on particulate methane monooxygenase activity and structure. J.Biol.Chem., 289, 2014
6XZW	Crystal structure of the meningococcal vaccine antigen fHbp in complex with a cross-reactive human Fab. 分子名称: 1,2-ETHANEDIOL, Fab 4B3 (heavy chain), Fab 4B3 (light chain), ... 著者 Veggi, D, Cozzi, R. 登録日 2020-02-05 公開日 2020-10-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp. Plos Pathog., 16, 2020
4PHZ	Crystal structure of particulate methane monooxygenase from Methylocystis sp. ATCC 49242 (Rockwell) 分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, COPPER (II) ION, Particulate methane monooxygenase subunit A, ... 著者 Sirajuddin, S, Rosenzweig, A.C. 登録日 2014-05-07 公開日 2014-06-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Effects of zinc on particulate methane monooxygenase activity and structure. J.Biol.Chem., 289, 2014
4PI2	Crystal structure of particulate methane monooxygenase from Methylocystis sp. ATCC 49242 (Rockwell) soaked in zinc 分子名称: CACODYLATE ION, COPPER (II) ION, Particulate methane monooxygenase subunit A, ... 著者 Sirajuddin, S, Rosenzweig, A.C. 登録日 2014-05-07 公開日 2014-06-25 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (3.33 Å) 主引用文献 Effects of zinc on particulate methane monooxygenase activity and structure. J.Biol.Chem., 289, 2014
4U9R	Structure of the N-terminal Extension from Cupriavidus metallidurans CzcP 分子名称: 3,3',3''-phosphanetriyltripropanoic acid, CADMIUM ION, CzcP cation efflux P1-ATPase 著者 Smith, A.T, Rosenzweig, A.C. 登録日 2014-08-06 公開日 2015-07-08 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 A new metal binding domain involved in cadmium, cobalt and zinc transport. Nat.Chem.Biol., 11, 2015
7R3W	Crystal structure of the albicidin resistance protein STM3175 from Salmonella typhimurium 分子名称: Putative bacterial regulatory helix-turn-helix protein 著者 Dimos, N, Kosol, S, Suessmuth, R, Loll, B. 登録日 2022-02-08 公開日 2022-09-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Gene amplifications cause high-level resistance against albicidin in gram-negative bacteria. Plos Biol., 21, 2023
6MLJ	Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) S70A mutant from Salmonella typhimurium complexed with arginine 分子名称: ACETATE ION, ARGININE, Lysine/arginine/ornithine transport protein 著者 Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. 登録日 2018-09-27 公開日 2019-08-07 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein. Febs J., 287, 2020
6MLV	Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) Y14A mutant from Salmonella typhimurium 分子名称: Lysine/arginine/ornithine-binding periplasmic protein 著者 Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. 登録日 2018-09-28 公開日 2019-08-07 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.082 Å) 主引用文献 The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein. Febs J., 287, 2020
6MLO	Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) Y14A mutant from Salmonella typhimurium complexed with arginine 分子名称: ACETATE ION, ARGININE, GLYCEROL, ... 著者 Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. 登録日 2018-09-27 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.717 Å) 主引用文献 The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein. Febs J., 287, 2020
6MLI	Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) R77A mutant from Salmonella typhimurium complexed with histidine 分子名称: ACETATE ION, GLYCEROL, HISTIDINE, ... 著者 Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. 登録日 2018-09-27 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.883 Å) 主引用文献 The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein. Febs J., 287, 2020
6MLG	Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) R77A mutant from Salmonella typhimurium complexed with arginine 分子名称: ACETATE ION, ARGININE, Lysine/arginine/ornithine-binding periplasmic protein, ... 著者 Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. 登録日 2018-09-27 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.892 Å) 主引用文献 The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein. Febs J., 287, 2020
6MLN	Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) S72A mutant from Salmonella typhimurium complexed with arginine 分子名称: ACETATE ION, ARGININE, GLYCEROL, ... 著者 Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. 登録日 2018-09-27 公開日 2019-08-07 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.721 Å) 主引用文献 The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein. Febs J., 287, 2020
6MLP	Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) Y14A mutant from Salmonella typhimurium complexed with histidine 分子名称: ACETATE ION, GLYCEROL, HISTIDINE, ... 著者 Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. 登録日 2018-09-27 公開日 2019-08-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.485 Å) 主引用文献 The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein. Febs J., 287, 2020
6MKW	Crystal structure of the periplasmic Lysine-, Arginine-, Ornithine-binding protein (LAO) D11A mutant from Salmonella typhimurium complexed with histidine 分子名称: GLYCEROL, HISTIDINE, Lysine/arginine/ornithine transport protein 著者 Romero-Romero, S, Vergara, R, Espinoza-Perez, G, Rodriguez-Romero, A. 登録日 2018-09-26 公開日 2019-08-07 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 The interplay of protein-ligand and water-mediated interactions shape affinity and selectivity in the LAO binding protein. Febs J., 287, 2020
6Y39	HapE-P88L mutant CCAAT-binding complex from Aspergillus nidulans with cycA DNA 分子名称: CBFD_NFYB_HMF domain-containing protein, CHLORIDE ION, DNA (25 mer), ... 著者 Groll, M, Huber, E.M. 登録日 2020-02-17 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis of HapE P88L -linked antifungal triazole resistance in Aspergillus fumigatus . Life Sci Alliance, 3, 2020
6P9S	E.coli LpxA in complex with UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc and Compound 7 分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Ma, X, Shia, S, Ornelas, E. 登録日 2019-06-10 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. J.Am.Chem.Soc., 142, 2020
6P9Q	E.coli LpxA in complex with UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc and Compound 2 分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Ma, X, Shia, S, Ornelas, E. 登録日 2019-06-10 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. J.Am.Chem.Soc., 142, 2020
5TR6	Discovery of TAK-659, an Orally Available Investigational Inhibitor of Spleen Tyrosine Kinase (SYK) 分子名称: 1,2-ETHANEDIOL, 6-{[(1R,2S)-2-aminocyclohexyl]amino}-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one, Tyrosine-protein kinase SYK 著者 Yano, J, Jennings, A, Lam, B, Hoffman, I.D. 登録日 2016-10-25 公開日 2016-11-30 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Discovery of TAK-659 an orally available investigational inhibitor of Spleen Tyrosine Kinase (SYK). Bioorg. Med. Chem. Lett., 26, 2016
6ZZB	Crystal structure of the Eimeria tenella surface antigen protein SAG19 分子名称: SAG family member (Sag19), SULFATE ION 著者 Dix, S.R, Rice, D.W. 登録日 2020-08-04 公開日 2021-03-24 最終更新日 2021-03-31 実験手法 X-RAY DIFFRACTION (1.322 Å) 主引用文献 The structure of a major surface antigen SAG19 from Eimeria tenella unifies the Eimeria SAG family. Commun Biol, 4, 2021
6P9P	E.coli LpxA in complex with Compound 1 分子名称: 3-[2-(4-methoxyphenyl)-2-oxoethyl]-5,5-diphenylimidazolidine-2,4-dione, Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, ... 著者 Ma, X, Shia, S, Ornelas, E. 登録日 2019-06-10 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. J.Am.Chem.Soc., 142, 2020
6CPD	Crystal structure of PmoD soluble domain from Methylocystis sp. ATCC 49242 (Rockwell) 分子名称: COPPER (I) ION, PmoD, SULFATE ION 著者 Fisher, O.S, Rosenzweig, A.C. 登録日 2018-03-13 公開日 2018-10-31 最終更新日 2019-12-04 実験手法 X-RAY DIFFRACTION (1.903 Å) 主引用文献 Characterization of a long overlooked copper protein from methane- and ammonia-oxidizing bacteria. Nat Commun, 9, 2018
6P9R	E.coli LpxA in complex with UDP-3-O-(R-3-hydroxymyristoyl)-GlcNAc and Compound 6 分子名称: Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, DIMETHYL SULFOXIDE, PHOSPHATE ION, ... 著者 Ma, X, Shia, S, Ornelas, E. 登録日 2019-06-10 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Two Distinct Mechanisms of Inhibition of LpxA Acyltransferase Essential for Lipopolysaccharide Biosynthesis. J.Am.Chem.Soc., 142, 2020

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